inositol has been researched along with Panic Disorder in 5 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The frequency and severity of panic attacks and the severity of agoraphobia declined significantly more after inositol than after placebo administration." | 9.08 | Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder. ( Aviv, A; Belmaker, RH; Benjamin, J; Fux, M; Levine, J; Levy, D, 1995) |
| "Only 70% of patients respond to current treatments for panic disorder, and many discontinue drugs because of side effects." | 6.70 | Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. ( Benjamin, J; Frolov, K; Fux, M; Palatnik, A, 2001) |
| "The frequency and severity of panic attacks and the severity of agoraphobia declined significantly more after inositol than after placebo administration." | 5.08 | Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder. ( Aviv, A; Belmaker, RH; Benjamin, J; Fux, M; Levine, J; Levy, D, 1995) |
| "Clinical trials indicate that inositol may be effective in the treatment of patients with depression, panic disorder and obsessive compulsive disorder (OCD), but not in the treatment of patients with schizophrenia, Alzheimer's disease, ADHD or autism." | 4.81 | The effects of inositol treatment in animal models of psychiatric disorders. ( Belmaker, RH; Einat, H, 2001) |
| "Only 70% of patients respond to current treatments for panic disorder, and many discontinue drugs because of side effects." | 2.70 | Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. ( Benjamin, J; Frolov, K; Fux, M; Palatnik, A, 2001) |
| "Inositol is a simple polyol precursor in a second messenger system important in the brain." | 2.68 | Controlled trials of inositol in psychiatry. ( Levine, J, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kinrys, G | 1 |
| Coleman, E | 1 |
| Rothstein, E | 1 |
| Benjamin, J | 2 |
| Levine, J | 2 |
| Fux, M | 2 |
| Aviv, A | 1 |
| Levy, D | 1 |
| Belmaker, RH | 2 |
| Einat, H | 1 |
| Palatnik, A | 1 |
| Frolov, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inositol for Comorbid Anxiety in Children and Adolescents With Bipolar Disorder[NCT02811133] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2023-08-31 | Withdrawn (stopped due to Funding terminated) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for inositol and Panic Disorder
| Article | Year |
|---|---|
Natural remedies for anxiety disorders: potential use and clinical applications.
Topics: Anti-Anxiety Agents; Antioxidants; Anxiety Disorders; Humans; Hypericum; Inositol; Kava; Melatonin; | 2009 |
The effects of inositol treatment in animal models of psychiatric disorders.
Topics: Affect; Animals; Arousal; Depressive Disorder; Disease Models, Animal; Humans; Inositol; Mental Diso | 2001 |
3 trials available for inositol and Panic Disorder
| Article | Year |
|---|---|
Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder.
Topics: Adult; Agoraphobia; Cross-Over Studies; Double-Blind Method; Female; Humans; Inositol; Male; Panic D | 1995 |
Controlled trials of inositol in psychiatry.
Topics: Adult; Alzheimer Disease; Depressive Disorder; Double-Blind Method; Female; Humans; Inositol; Male; | 1997 |
Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Anxiety Agents; Chi-Square Distribution; Cross-O | 2001 |