Page last updated: 2024-10-19

inositol and Panic Attacks

inositol has been researched along with Panic Attacks in 5 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
"The frequency and severity of panic attacks and the severity of agoraphobia declined significantly more after inositol than after placebo administration."9.08Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder. ( Aviv, A; Belmaker, RH; Benjamin, J; Fux, M; Levine, J; Levy, D, 1995)
"Only 70% of patients respond to current treatments for panic disorder, and many discontinue drugs because of side effects."6.70Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. ( Benjamin, J; Frolov, K; Fux, M; Palatnik, A, 2001)
"The frequency and severity of panic attacks and the severity of agoraphobia declined significantly more after inositol than after placebo administration."5.08Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder. ( Aviv, A; Belmaker, RH; Benjamin, J; Fux, M; Levine, J; Levy, D, 1995)
"Clinical trials indicate that inositol may be effective in the treatment of patients with depression, panic disorder and obsessive compulsive disorder (OCD), but not in the treatment of patients with schizophrenia, Alzheimer's disease, ADHD or autism."4.81The effects of inositol treatment in animal models of psychiatric disorders. ( Belmaker, RH; Einat, H, 2001)
"Only 70% of patients respond to current treatments for panic disorder, and many discontinue drugs because of side effects."2.70Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. ( Benjamin, J; Frolov, K; Fux, M; Palatnik, A, 2001)
"Inositol is a simple polyol precursor in a second messenger system important in the brain."2.68Controlled trials of inositol in psychiatry. ( Levine, J, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kinrys, G1
Coleman, E1
Rothstein, E1
Benjamin, J2
Levine, J2
Fux, M2
Aviv, A1
Levy, D1
Belmaker, RH2
Einat, H1
Palatnik, A1
Frolov, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Inositol for Comorbid Anxiety in Children and Adolescents With Bipolar Disorder[NCT02811133]Phase 1/Phase 20 participants (Actual)Interventional2023-08-31Withdrawn (stopped due to Funding terminated)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for inositol and Panic Attacks

ArticleYear
Natural remedies for anxiety disorders: potential use and clinical applications.
    Depression and anxiety, 2009, Volume: 26, Issue:3

    Topics: Anti-Anxiety Agents; Antioxidants; Anxiety Disorders; Humans; Hypericum; Inositol; Kava; Melatonin;

2009
The effects of inositol treatment in animal models of psychiatric disorders.
    Journal of affective disorders, 2001, Volume: 62, Issue:1-2

    Topics: Affect; Animals; Arousal; Depressive Disorder; Disease Models, Animal; Humans; Inositol; Mental Diso

2001

Trials

3 trials available for inositol and Panic Attacks

ArticleYear
Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder.
    The American journal of psychiatry, 1995, Volume: 152, Issue:7

    Topics: Adult; Agoraphobia; Cross-Over Studies; Double-Blind Method; Female; Humans; Inositol; Male; Panic D

1995
Controlled trials of inositol in psychiatry.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1997, Volume: 7, Issue:2

    Topics: Adult; Alzheimer Disease; Depressive Disorder; Double-Blind Method; Female; Humans; Inositol; Male;

1997
Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Anxiety Agents; Chi-Square Distribution; Cross-O

2001