inositol has been researched along with Non-alcoholic Fatty Liver Disease in 9 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Non-alcoholic Fatty Liver Disease: Fatty liver finding without excessive ALCOHOL CONSUMPTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In hepatic encephalopathy (HE), osmotic stressors promoting brain edema result in a compensatory drop in the astrocyte metabolite myo-inositol (mI)." | 3.96 | Brain MR Spectroscopy Markers of Encephalopathy Due to Nonalcoholic Steatohepatitis. ( Cole, S; Csete, M; King, KS; Mena, E; Tran, TT; Wei, K, 2020) |
| "Non-alcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic hepatic injury in the world." | 2.90 | Pinitol consumption improves liver health status by reducing oxidative stress and fatty acid accumulation in subjects with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial. ( Kwon, O; Kwon, SW; Lee, E; Lim, Y, 2019) |
| "Nonalcoholic fatty liver disease is the most prevalent liver disease characterized by excessive lipid accumulation in hepatocytes." | 1.72 | Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway. ( Huang, Y; Huo, Z; Liang, J; Luan, H; Shen, Y; Sheng, L; Wu, F; Zhang, X, 2022) |
| "The HFHFr diet induced severe NAFLD in terms of steatosis, hepatitis, and fibrosis." | 1.72 | The effects of the voglibose on non-alcoholic fatty liver disease in mice model. ( Bae, J; Cha, BS; Kang, ES; Lee, BW; Lee, JY; Lee, M; Lee, YH; Shin, E, 2022) |
| "Non-alcoholic fatty liver disease (NAFLD) is caused by imbalance in lipid metabolism." | 1.72 | Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis. ( Hu, C; Ji, N; Lu, Y; Luo, Y; Zhou, B, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 6 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Huo, Z | 1 |
| Luan, H | 1 |
| Huang, Y | 1 |
| Shen, Y | 1 |
| Sheng, L | 1 |
| Liang, J | 1 |
| Wu, F | 1 |
| Bae, J | 1 |
| Lee, JY | 1 |
| Shin, E | 1 |
| Lee, M | 1 |
| Lee, YH | 1 |
| Lee, BW | 1 |
| Kang, ES | 1 |
| Cha, BS | 1 |
| Zhou, B | 1 |
| Luo, Y | 1 |
| Ji, N | 1 |
| Hu, C | 1 |
| Lu, Y | 1 |
| Mukherjee, S | 1 |
| Chakraborty, M | 1 |
| Haubner, J | 1 |
| Ernst, G | 1 |
| DePasquale, M | 1 |
| Carpenter, D | 1 |
| Barrow, JC | 1 |
| Chakraborty, A | 1 |
| Tran, TT | 1 |
| Wei, K | 1 |
| Cole, S | 1 |
| Mena, E | 1 |
| Csete, M | 1 |
| King, KS | 1 |
| Pani, A | 1 |
| Giossi, R | 1 |
| Menichelli, D | 1 |
| Fittipaldo, VA | 1 |
| Agnelli, F | 1 |
| Inglese, E | 1 |
| Romandini, A | 1 |
| Roncato, R | 1 |
| Pintaudi, B | 1 |
| Del Sole, F | 1 |
| Scaglione, F | 1 |
| Shimada, M | 1 |
| Ichigo, Y | 1 |
| Shirouchi, B | 1 |
| Takashima, S | 1 |
| Inagaki, M | 1 |
| Nakagawa, T | 1 |
| Hayakawa, T | 1 |
| Lee, E | 1 |
| Lim, Y | 1 |
| Kwon, SW | 1 |
| Kwon, O | 1 |
| Kakazu, E | 1 |
| Mauer, AS | 1 |
| Yin, M | 1 |
| Malhi, H | 1 |
1 review available for inositol and Non-alcoholic Fatty Liver Disease
| Article | Year |
|---|---|
Inositol and Non-Alcoholic Fatty Liver Disease: A Systematic Review on Deficiencies and Supplementation.
Topics: Animals; Cholesterol; Dietary Supplements; Female; Glutathione Peroxidase; Humans; Inositol; Insulin | 2020 |
1 trial available for inositol and Non-alcoholic Fatty Liver Disease
| Article | Year |
|---|---|
Pinitol consumption improves liver health status by reducing oxidative stress and fatty acid accumulation in subjects with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial.
Topics: Dietary Supplements; Double-Blind Method; Enzymes; Fatty Acids; Female; Humans; Inositol; Lipids; Li | 2019 |
7 other studies available for inositol and Non-alcoholic Fatty Liver Disease
| Article | Year |
|---|---|
Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway.
Topics: Animals; Apigenin; Autophagy; Endoribonucleases; Fatty Acids; Glucuronates; Inositol; Lipid Metaboli | 2022 |
The effects of the voglibose on non-alcoholic fatty liver disease in mice model.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Fructose; Glucose; Glycoside Hydrolase Inhibitors; | 2022 |
Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis.
Topics: AMP-Activated Protein Kinases; Animals; Homeostasis; Inositol; Lipids; Lipogenesis; Mice; Non-alcoho | 2022 |
The IP6K Inhibitor LI-2242 Ameliorates Diet-Induced Obesity, Hyperglycemia, and Hepatic Steatosis in Mice by Improving Cell Metabolism and Insulin Signaling.
Topics: Animals; Diet; Diphosphates; Hyperglycemia; Inositol; Insulin; Insulin Resistance; Lipid Metabolism; | 2023 |
Brain MR Spectroscopy Markers of Encephalopathy Due to Nonalcoholic Steatohepatitis.
Topics: Aged; Biomarkers; Brain; Brain Edema; Female; Glutamine; Hepatic Encephalopathy; Humans; Inositol; M | 2020 |
Treatment with myo-inositol attenuates binding of the carbohydrate-responsive element-binding protein to the ChREBP-β and FASN genes in rat nonalcoholic fatty liver induced by high-fructose diet.
Topics: Acetyl-CoA Carboxylase; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Diet; | 2019 |
Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner.
Topics: Cells, Cultured; Ceramides; Endoplasmic Reticulum Stress; Endoribonucleases; Extracellular Vesicles; | 2016 |