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inositol and Neurofibromatosis 1

inositol has been researched along with Neurofibromatosis 1 in 3 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rodrigues, AC1
Ferraz-Filho, JR1
Torres, US1
da Rocha, AJ1
Muniz, MP1
Souza, AS1
Goloni-Bertollo, EM1
Pavarino, ÉC1
Pascual-Castroviejo, I1
Pascual-Pascual, SI1
Velazquez-Fragua, R1
Viaño, J1
Alkan, A1
Sarac, K1
Kutlu, R1
Yakinci, C1
Sigirci, A1
Aslan, M1
Ozcan, H1
Yologlu, S1

Reviews

1 review available for inositol and Neurofibromatosis 1

ArticleYear
[Corpus callosum tumor as the presenting symptom of neurofibromatosis type 1 in a patient and literature review].
    Revista de neurologia, 2012, Nov-01, Volume: 55, Issue:9

    Topics: Brain Neoplasms; Brain Stem Neoplasms; Cerebellar Neoplasms; Child, Preschool; Choline; Corpus Callo

2012

Other Studies

2 other studies available for inositol and Neurofibromatosis 1

ArticleYear
Is magnetic resonance spectroscopy capable of detecting metabolic abnormalities in neurofibromatosis type 1 that are not revealed in brain parenchyma of normal appearance?
    Pediatric neurology, 2015, Volume: 52, Issue:3

    Topics: Adolescent; Aspartic Acid; Brain; Case-Control Studies; Child; Child, Preschool; Choline; Creatine;

2015
Proton MR spectroscopy features of normal appearing white matter in neurofibromatosis type 1.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Child; Child, Preschool; Choline; Creatinine; Female; Human

2003