inositol has been researched along with Nerve Degeneration in 13 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Strongly elevated concentrations of myo-inositol in conjunction with normal or increased choline-containing compounds in all regions investigated point to astrocytosis and demyelination." | 3.72 | Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease. ( Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Haupt, M; Meins, M; Sperner, J; Stephani, U, 2003) |
| " We also did not find a correlation between the amount of Glx and the initial Glasgow Coma Scale score, duration of coma, nor with changes in spectral metabolites, including N-acetyl aspartate, choline, and myoinositol." | 3.72 | Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury. ( Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K, 2004) |
| "To evaluate cerebral biochemical abnormalities in patients with frontotemporal dementia and Alzheimer disease and to determine whether proton (hydrogen-1) magnetic resonance (MR) spectroscopy can help differentiate among these two patient groups and healthy (control) subjects." | 3.69 | Frontotemporal dementia and early Alzheimer disease: differentiation with frontal lobe H-1 MR spectroscopy. ( Chang, L; Ernst, T; Mehringer, CM; Melchor, R, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 8 (61.54) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erichsen, AK | 1 |
| Server, A | 1 |
| Landrø, NI | 1 |
| Sandvik, L | 1 |
| Tallaksen, CM | 1 |
| Duarte, JM | 1 |
| Carvalho, RA | 1 |
| Cunha, RA | 1 |
| Gruetter, R | 1 |
| Cosker, KE | 1 |
| Segal, RA | 1 |
| Brockmann, K | 1 |
| Dechent, P | 1 |
| Meins, M | 1 |
| Haupt, M | 1 |
| Sperner, J | 1 |
| Stephani, U | 1 |
| Frahm, J | 2 |
| Hanefeld, F | 2 |
| Ashwal, S | 1 |
| Holshouser, B | 1 |
| Tong, K | 1 |
| Serna, T | 1 |
| Osterdock, R | 1 |
| Gross, M | 1 |
| Kido, D | 1 |
| Brunetti-Pierri, N | 1 |
| Bhattacharjee, MB | 1 |
| Wang, ZJ | 1 |
| Wenger, DA | 1 |
| Potocki, L | 1 |
| Hunter, J | 1 |
| Scaglia, F | 1 |
| Kruse, B | 1 |
| Bruhn, H | 1 |
| Ernst, T | 1 |
| Chang, L | 1 |
| Melchor, R | 1 |
| Mehringer, CM | 1 |
| Sundkvist, G | 1 |
| Dahlin, LB | 1 |
| Nilsson, H | 1 |
| Eriksson, KF | 1 |
| Lindgärde, F | 1 |
| Rosén, I | 1 |
| Lattimer, SA | 1 |
| Sima, AA | 1 |
| Sullivan, K | 1 |
| Greene, DA | 1 |
| Tabata, H | 1 |
| Ikegami, H | 1 |
| Kariya, K | 1 |
| Khiat, A | 1 |
| Yared, Z | 1 |
| Bard, C | 1 |
| Lacroix, A | 1 |
| Boulanger, Y | 1 |
| Dubois-Dalcq, M | 1 |
| Menu, R | 1 |
| Buyse, M | 1 |
| Kusama, H | 1 |
| Stewart, MA | 1 |
13 other studies available for inositol and Nerve Degeneration
| Article | Year |
|---|---|
Proton magnetic resonance spectroscopy and cognition in patients with spastin mutations.
Topics: Adenosine Triphosphatases; Adult; Aspartic Acid; Biomarkers; Choline; Cognition Disorders; Creatine; | 2009 |
Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Caffeine; Central Nervous System Stimulants; Chronic Disease; Diabetes Melli | 2009 |
The longer U(T)R, the further you go.
Topics: 3' Untranslated Regions; Aging; Animals; Cell Enlargement; Gene Expression; Gene Expression Profilin | 2010 |
Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease.
Topics: Alexander Disease; Aspartic Acid; Brain; Child; Child, Preschool; Demyelinating Diseases; Disease Pr | 2003 |
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Com | 2004 |
Brain proton magnetic resonance spectroscopy and neuromuscular pathology in a patient with GM1 gangliosidosis.
Topics: Aspartic Acid; Axons; Biomarkers; Brain; Female; Gangliosidosis, GM1; Gliosis; Humans; Infant; Inosi | 2008 |
In vivo proton magnetic resonance spectroscopy of the brain in a patient with L-2-hydroxyglutaric acidemia.
Topics: Adolescent; Aspartic Acid; Biomarkers; Brain; Female; Glutarates; Humans; Inositol; Magnetic Resonan | 1994 |
Frontotemporal dementia and early Alzheimer disease: differentiation with frontal lobe H-1 MR spectroscopy.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Dementia; Discriminant Analysis; Female; | 1997 |
Sorbitol and myo-inositol levels and morphology of sural nerve in relation to peripheral nerve function and clinical neuropathy in men with diabetic, impaired, and normal glucose tolerance.
Topics: Diabetes Mellitus, Type 1; Diabetic Neuropathies; Glucose Intolerance; Glucose Tolerance Test; Human | 2000 |
Spontaneous age-related peripheral neuropathy in B6C3F1 mice.
Topics: Aging; Animals; Axons; Blood Glucose; Body Temperature; Cell Division; Female; Glycated Hemoglobin; | 2000 |
Long-term brain metabolic alterations in exogenous Cushing's syndrome as monitored by proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Brain Injuries; Cell Membrane; Choline; Crea | 2001 |
Influence of fatty acids on fine structure of cultured neurons. An experimental approach to Refsum's disease.
Topics: Animals; Culture Techniques; Fatty Acids; Ganglia, Spinal; Inositol; Microscopy, Electron; Nerve Deg | 1972 |
Levels of myo-inositol in normal and degenerating peripheral nerve.
Topics: Animals; Anura; Chromatography, Gas; Crustacea; Diet; Freeze Drying; Galactose; Haplorhini; Inositol | 1970 |