inositol has been researched along with Neoplasms in 31 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inositol is an essential nutrient, obtained either by uptake from the environment or by de novo synthesis from glucose." | 2.82 | The paradoxical role of inositol in cancer: a consequence of the metabolic state of a tumor. ( Case, KC; Greenberg, ML; Schmidtke, MW, 2022) |
| "Cell expansion and metastasis are considered hallmarks of tumour progression." | 2.46 | Glycosidated phospholipids: uncoupling of signalling pathways at the plasma membrane. ( Danker, K; Reutter, W; Semini, G, 2010) |
| "A striking anticancer action of IP(6) was demonstrated in different experimental models." | 2.43 | Protection against cancer by dietary IP6 and inositol. ( Shamsuddin, AM; Vucenik, I, 2006) |
| "A striking anticancer effect of IP6 was demonstrated in different experimental models." | 2.42 | Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic. ( Shamsuddin, AM; Vucenik, I, 2003) |
| "Prostate cancer, the most prevalent non-cutaneous cancer in men, is associated with increased age." | 1.35 | The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats. ( Lindgren, BR; Sinha, AA; Wilson, MJ, 2008) |
| "Multidrug-resistant (MDR) cancer cells have been shown to have an accumulation of glucosylceramide (GlcCer)." | 1.31 | Elevation of glucosylceramide in multidrug-resistant cancer cells and accumulation in cytoplasmic droplets. ( Aouali, N; Belhoussine, R; Levade, T; Manfait, M; Morjani, H; Veldman, RJ, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (45.16) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (19.35) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 7 (22.58) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, Q | 1 |
| Wang, L | 1 |
| Huang, J | 1 |
| Zhao, W | 1 |
| Wu, J | 1 |
| Collins, NB | 1 |
| Al Abosy, R | 1 |
| Miller, BC | 1 |
| Bi, K | 1 |
| Zhao, Q | 1 |
| Quigley, M | 1 |
| Ishizuka, JJ | 1 |
| Yates, KB | 1 |
| Pope, HW | 1 |
| Manguso, RT | 1 |
| Shrestha, Y | 1 |
| Wadsworth, M | 1 |
| Hughes, T | 1 |
| Shalek, AK | 1 |
| Boehm, JS | 1 |
| Hahn, WC | 1 |
| Doench, JG | 1 |
| Haining, WN | 1 |
| Case, KC | 1 |
| Schmidtke, MW | 1 |
| Greenberg, ML | 1 |
| Lu, Y | 1 |
| Shi, Y | 1 |
| Liu, Y | 1 |
| Luo, Z | 1 |
| Zhang, J | 1 |
| Jiang, M | 1 |
| Li, X | 1 |
| Liu, X | 1 |
| Guo, X | 1 |
| Qin, B | 1 |
| Yin, H | 1 |
| Du, Y | 1 |
| Qiu, Y | 1 |
| Lou, Y | 1 |
| Guan, G | 1 |
| Luo, L | 1 |
| You, J | 1 |
| Salvagno, C | 1 |
| Mandula, JK | 1 |
| Rodriguez, PC | 1 |
| Cubillos-Ruiz, JR | 1 |
| Chen, Q | 1 |
| Shen, L | 1 |
| Li, S | 1 |
| Yang, SX | 1 |
| Song, CG | 1 |
| Kuang, Y | 1 |
| Liu, B | 1 |
| Zhang, YX | 1 |
| Zhang, MZ | 1 |
| Zhang, CY | 1 |
| Ding, G | 1 |
| Qin, JC | 1 |
| Bizzarri, M | 1 |
| Dinicola, S | 1 |
| Cucina, A | 1 |
| Semini, G | 2 |
| Hildmann, A | 1 |
| von Haefen, C | 1 |
| Danker, K | 2 |
| Wilson, MJ | 1 |
| Lindgren, BR | 1 |
| Sinha, AA | 1 |
| HERBST, WP | 1 |
| BAGLEY, CE | 1 |
| Reutter, W | 1 |
| TATUM, EL | 1 |
| RITCHEY, MG | 1 |
| Serkova, NJ | 1 |
| Brown, MS | 1 |
| Cocco, L | 1 |
| Manzoli, L | 1 |
| Barnabei, O | 1 |
| Gilmour, RS | 1 |
| Martelli, AM | 1 |
| EAGLE, H | 2 |
| OYAMA, VI | 2 |
| LEVY, M | 2 |
| FREEMAN, A | 1 |
| FREEMAN, AE | 1 |
| AVIOLI, LV | 1 |
| MCDONALD, JE | 1 |
| SINGER, RA | 1 |
| HENNEMAN, PH | 1 |
| Vucenik, I | 2 |
| Shamsuddin, AM | 2 |
| SCHAEFER, AE | 1 |
| COPELAND, DH | 1 |
| SALMON, WD | 1 |
| HALE, OM | 1 |
| REBERT, AF | 1 |
| Lembach, K | 2 |
| Charalampous, FC | 3 |
| Jariwalla, RJ | 1 |
| Morjani, H | 1 |
| Aouali, N | 1 |
| Belhoussine, R | 1 |
| Veldman, RJ | 1 |
| Levade, T | 1 |
| Manfait, M | 1 |
| Trznadel, K | 1 |
| Walasek, L | 1 |
| Lutz, W | 1 |
| Nagański, T | 1 |
| Fajndt, S | 1 |
| Warmsley, AM | 1 |
| Phillips, B | 1 |
| Pasternak, CA | 1 |
| de Siebenthal, J | 1 |
| Jenny, M | 1 |
| Narumi, K | 1 |
| Arita, M | 1 |
| Kitagawa, M | 1 |
| Kumazawa, A | 1 |
| Tsumita, T | 1 |
11 reviews available for inositol and Neoplasms
| Article | Year |
|---|---|
The paradoxical role of inositol in cancer: a consequence of the metabolic state of a tumor.
Topics: Cell Proliferation; Humans; Inositol; Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Prot | 2022 |
Decoding endoplasmic reticulum stress signals in cancer cells and antitumor immunity.
Topics: Endoplasmic Reticulum Stress; Endoribonucleases; Humans; Inositol; Neoplasms; Protein Serine-Threoni | 2022 |
Emerging role of inositol monophosphatase in cancer.
Topics: 5'-Nucleotidase; Humans; Inositol; Inositol Phosphates; Neoplasms; Phosphoric Monoester Hydrolases | 2023 |
Modulation of both Insulin Resistance and Cancer Growth by Inositol.
Topics: Animals; Blood Glucose; Growth Inhibitors; Humans; Inositol; Insulin Resistance; Neoplasms; Tumor Bu | 2017 |
Glycosidated phospholipids - a promising group of anti-tumour lipids.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Differentiation; Cell Movement; Cell | 2014 |
Glycosidated phospholipids: uncoupling of signalling pathways at the plasma membrane.
Topics: Animals; Antineoplastic Agents; Cell Membrane; Cell Movement; Cell Proliferation; Glycosides; Humans | 2010 |
Quantitative analysis in magnetic resonance spectroscopy: from metabolic profiling to in vivo biomarkers.
Topics: Biomarkers; Body Fluids; Humans; Inositol; Isotope Labeling; Magnetic Resonance Imaging; Magnetic Re | 2012 |
Re-examination of the significance of nuclear localization of PLCbeta1 in the likelihood of its involvement in neoplastic cell growth.
Topics: Animals; Cell Division; Cell Nucleus; Gene Expression Regulation, Neoplastic; Humans; Inositol; Isoe | 2003 |
Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Colonic Neoplasms; Disease Mod | 2003 |
Protection against cancer by dietary IP6 and inositol.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic | 2006 |
Rice-bran products: phytonutrients with potential applications in preventive and clinical medicine.
Topics: Animals; Anticholesteremic Agents; Coumaric Acids; Dietary Fiber; Fatty Liver; Free Radical Scavenge | 2001 |
20 other studies available for inositol and Neoplasms
| Article | Year |
|---|---|
Topics: Amides; Amino Acids; Cell Line, Tumor; Drug Carriers; Esters; Inositol; Nanoparticles; Neoplasms; Pa | 2021 |
PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment.
Topics: Animals; Carcinogenesis; CD8-Positive T-Lymphocytes; Class I Phosphatidylinositol 3-Kinases; Disease | 2022 |
A therapeutic DC vaccine with maintained immunological activity exhibits robust anti-tumor efficacy.
Topics: alpha-Tocopherol; Antigens, Neoplasm; Cancer Vaccines; Dendritic Cells; Endoribonucleases; Humans; I | 2022 |
Cytotoxic Activity of Inositol Angelates and Tirucallane-Type Alkaloids from
Topics: Aglaia; Alkaloids; Cell Proliferation; Hep G2 Cells; Humans; Inositol; Neoplasms; Triterpenes | 2020 |
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats.
Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Cyclohexenes; Dietary Supplements; Disease Mode | 2008 |
Observations in the use of inositol in advanced malignancy of the genito-urinary tract.
Topics: Inositol; Neoplasms; Urinary Tract; Urogenital Neoplasms; Urogenital System; Urologic Neoplasms | 1948 |
Vitamin content of mouse epidermis during methylcholanthrene carcinogenesis; biotin, choline, inositol, rho-aminobenzoic acid, and pyridoxine.
Topics: 4-Aminobenzoic Acid; Acids; Biotin; Carcinogenesis; Choline; Epidermis; Inositol; Methylcholanthrene | 1946 |
Myo-inositol as an essential growth factor for normal and malignant human cells in tissue culture.
Topics: Inositol; Intercellular Signaling Peptides and Proteins; Neoplasms; Research Design; Tissue Culture | 1956 |
Myo-Inositol as an essential growth factor for normal and malignant human cells in tissue culture.
Topics: Carbohydrate Metabolism; Humans; Inositol; Intercellular Signaling Peptides and Proteins; Neoplasms | 1957 |
A NEW ORAL ISOTOPIC TEST OF CALCIUM ABSORPTION.
Topics: Adolescent; Bone Neoplasms; Calcinosis; Calcium; Calcium Isotopes; Ergocalciferols; Feces; Geriatric | 1965 |
The influence of riboflavin, pyridoxine, inositol, and protein depletion- repletion upon the induction of neoplasms by choline deficiency.
Topics: Choline Deficiency; Folic Acid; Humans; Inositol; Neoplasms; Pyridoxine; Riboflavin; Vitamin B Compl | 1950 |
[Vitamins E and K and inositol in the treatment of tumors of corn induced by colchicine].
Topics: Colchicine; Humans; Inositol; Neoplasms; Vitamin E; Vitamins; Zea mays | 1951 |
Metabolic functions of myo-inositol. V. Utilization of glycine and serine in nucleotide and nucleic acid biosynthesis by inositol-deficient KB cells.
Topics: Carbon Isotopes; Culture Techniques; Glycine; Humans; Inositol; Mouth Neoplasms; Neoplasms; Nucleic | 1967 |
Metabolic functions of myo-inositol. VI. Impairment of amino acid transport in KB cells caused by inositol deficiency.
Topics: Aminoisobutyric Acids; Carbon Isotopes; Culture Techniques; Glycine; Humans; Inositol; Kinetics; Mou | 1967 |
Elevation of glucosylceramide in multidrug-resistant cancer cells and accumulation in cytoplasmic droplets.
Topics: Cell Nucleus; Cytoplasm; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glucosy | 2001 |
[Blood serum concentration and urinary excretion of myoinositol in patients with malignant tumors].
Topics: Adult; Aged; Female; Humans; Inositol; Male; Middle Aged; Neoplasms | 1977 |
The use of zonal centrifugation to study membrane formation during the life cycle of mammalian cells. Synthesis of 'marker' enzymes and other components of cellular organelles.
Topics: Cell Division; Cell Nucleus; Centrifugation, Zonal; Choline; Culture Techniques; Electron Transport | 1970 |
[The hypercalcemias and their treatment].
Topics: Adrenal Cortex Hormones; Edetic Acid; Female; Humans; Hypercalcemia; Hyperthyroidism; Hypothyroidism | 1967 |
Gaschromatographic analysis of free myo- and scyllo-inositols in animal tissues.
Topics: Adrenal Glands; Animals; Aorta, Abdominal; Bone Marrow; Brain Chemistry; Cattle; Chromatography, Gas | 1969 |
Metabolic functions of myo-inositol. VII. Role of inositol in the transport of alpha-aminoisobutyric acid in KB cells.
Topics: Aminoisobutyric Acids; Biological Transport, Active; Carbon Isotopes; Culture Techniques; Depression | 1969 |