Page last updated: 2024-10-19

inositol and Neoplasm Metastasis

inositol has been researched along with Neoplasm Metastasis in 9 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"The most characteristic signatures on spectroscopy were high choline (Cho) in medulloblastoma (p < 0."3.91Magnetic resonance spectroscopy in posterior fossa tumours: the tumour spectroscopic signature may improve discrimination in adults among haemangioblastoma, ependymal tumours, medulloblastoma, and metastasis. ( Aguilera, C; Arús, C; Camins, A; Cos, M; Majós, C; Mora, P; Muntané, A; Pons, A, 2019)
"Cell expansion and metastasis are considered hallmarks of tumour progression."2.46Glycosidated phospholipids: uncoupling of signalling pathways at the plasma membrane. ( Danker, K; Reutter, W; Semini, G, 2010)
"In this study, we investigated the anti-metastasis effects of D-pinitol in human prostate cancer cells."1.39D-pinitol inhibits prostate cancer metastasis through inhibition of αVβ3 integrin by modulating FAK, c-Src and NF-κB pathways. ( Chen, CC; Chen, WC; Hsieh, TF; Lee, SS; Lin, TH; Liu, HH; Tan, TW; Tang, CH; Tsai, TH, 2013)
"Using 36 biopsies from patients with brain tumors [12 glioblastoma multiforme (GBM); 10 low-grade (LG), including 7 schwannoma and 3 pylocytic astrocytoma; 7 meningioma (MN); 7 brain metastases (MT), including 3 adenocarcinoma and 4 breast cancer] and 9 control biopsies from patients undergoing surgery for epilepsy, we tested the hypothesis that the presence of glycine may distinguish among these brain tumor types."1.36High-resolution magic angle spinning magnetic resonance spectroscopy detects glycine as a biomarker in brain tumors. ( Andronesi, OC; Black, PM; Mintzopoulos, D; Righi, V; Tzika, AA, 2010)
" Toxicity studies allowed us to establish the LD50 (750 mg/kg body weight)."1.30A synthetic, nitrogenated antimetastatic and anti-angiogenic compound with low toxicity in vivo. ( Cerutti, ML; Colombo, L; D'Orio, E; Davel, L; Diament, M; Eiján, AM; Gelpi, ME; Leicach, SR; Parma, P; Stillitani, I, 1999)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's5 (55.56)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Minini, M1
Senni, A1
He, X1
Proietti, S1
Liguoro, D1
Catizone, A1
Giuliani, A1
Mancini, R1
Fuso, A1
Cucina, A1
Cao, Y1
Bizzarri, M1
Mora, P1
Pons, A1
Cos, M1
Camins, A1
Muntané, A1
Aguilera, C1
Arús, C1
Majós, C1
Lin, TH1
Tan, TW1
Tsai, TH1
Chen, CC1
Hsieh, TF1
Lee, SS1
Liu, HH1
Chen, WC1
Tang, CH1
Fu, M1
Song, Y1
Wen, Z1
Lu, X1
Cui, L1
Righi, V1
Andronesi, OC1
Mintzopoulos, D1
Black, PM1
Tzika, AA1
Danker, K1
Reutter, W1
Semini, G1
AVIOLI, LV1
MCDONALD, JE1
SINGER, RA1
HENNEMAN, PH1
Eiján, AM2
Puricelli, L1
Bal de Kier Joffé, E1
Elías, C1
Leicach, SR2
Cadenas, RA1
Cerutti, ML1
D'Orio, E1
Davel, L1
Colombo, L1
Parma, P1
Diament, M1
Stillitani, I1
Gelpi, ME1

Reviews

1 review available for inositol and Neoplasm Metastasis

ArticleYear
Glycosidated phospholipids: uncoupling of signalling pathways at the plasma membrane.
    British journal of pharmacology, 2010, Volume: 160, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Membrane; Cell Movement; Cell Proliferation; Glycosides; Humans

2010

Other Studies

8 other studies available for inositol and Neoplasm Metastasis

ArticleYear
miR-125a-5p impairs the metastatic potential in breast cancer via IP
    Cancer letters, 2021, 11-01, Volume: 520

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transi

2021
Magnetic resonance spectroscopy in posterior fossa tumours: the tumour spectroscopic signature may improve discrimination in adults among haemangioblastoma, ependymal tumours, medulloblastoma, and metastasis.
    European radiology, 2019, Volume: 29, Issue:6

    Topics: Adult; Biomarkers, Tumor; Choline; Diagnosis, Differential; Female; Hemangioblastoma; Humans; Infrat

2019
D-pinitol inhibits prostate cancer metastasis through inhibition of αVβ3 integrin by modulating FAK, c-Src and NF-κB pathways.
    International journal of molecular sciences, 2013, May-08, Volume: 14, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; CSK Tyrosine-Protein Kinase; Focal Adhesion Kinase 1; Human

2013
Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice.
    Nutrients, 2016, May-12, Volume: 8, Issue:5

    Topics: Adenocarcinoma; Animals; Colorectal Neoplasms; Female; Inositol; Liver Neoplasms; Mice; Mice, Inbred

2016
High-resolution magic angle spinning magnetic resonance spectroscopy detects glycine as a biomarker in brain tumors.
    International journal of oncology, 2010, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Biomarkers, Tumor; Brain Neoplasms; Glioblastoma; Glycine; Humans; Inositol; Magn

2010
A NEW ORAL ISOTOPIC TEST OF CALCIUM ABSORPTION.
    The Journal of clinical investigation, 1965, Volume: 44

    Topics: Adolescent; Bone Neoplasms; Calcinosis; Calcium; Calcium Isotopes; Ergocalciferols; Feces; Geriatric

1965
Action of nitrogenated and sulfonylated inositol derivatives upon the proliferation in vitro of normal mouse cells and tumor mouse cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1994, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Survival; Cells, Cul

1994
A synthetic, nitrogenated antimetastatic and anti-angiogenic compound with low toxicity in vivo.
    International journal of oncology, 1999, Volume: 14, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Fem

1999