inositol has been researched along with Muscle Contraction in 27 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sympathetic denervation of the iris muscle produces increases in both the breakdown of phosphatidylinositol 4,5-bisphosphate (PIP2) and in muscle contraction in response to norepinephrine (NE)." | 7.67 | Surgical sympathetic denervation increases alpha 1-adrenoceptor-mediated accumulation of myo-inositol trisphosphate and muscle contraction in rabbit iris dilator smooth muscle. ( Abdel-Latif, AA; Akhtar, RA, 1986) |
| "To determine the effects of ischemia-reperfusion (I/R) on alpha(1)-adrenergic-receptor (alpha(1)-AR) functions, alpha(1)-AR-mediated contraction, inositol phosphate (IP) accumulation, and alpha(1)-AR-G protein coupling were examined in the tail arteries of anesthetized rats after 60 min of ischemia and 60 min of reperfusion." | 3.71 | Selected contribution: effects of ischemia-reperfusion on vascular contractility and alpha(1)-adrenergic-receptor signaling in the rat tail artery. ( Cai, G; Friedman, E; Seasholtz, TM; Wang, HY, 2001) |
| "The systemic effects of trauma from large body surface area (% BSA) burns were evaluated in terms of second messenger levels involving polyinositol phosphates as they related to adenosine 3':5'-cyclic monophosphate (cAMP), myoplasmic Ca2+, and active tension." | 3.68 | Cross-talk of second messengers during the systemic trauma response following burn injury: how, when, and where. ( Kukulka, SP; Lilford, K; Tomera, JF, 1993) |
| "Sympathetic denervation of the iris muscle produces increases in both the breakdown of phosphatidylinositol 4,5-bisphosphate (PIP2) and in muscle contraction in response to norepinephrine (NE)." | 3.67 | Surgical sympathetic denervation increases alpha 1-adrenoceptor-mediated accumulation of myo-inositol trisphosphate and muscle contraction in rabbit iris dilator smooth muscle. ( Abdel-Latif, AA; Akhtar, RA, 1986) |
| " There was a decrease in sensitivity to isoproterenol in spontaneously beating right atria, electrically driven left atria and field-stimulated vas deferens associated with hypothyroidism, with no change in maximum response." | 3.67 | Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness. ( Abel, PW; Fox, AW; Johnson, RD; Juberg, EN; May, JM; Minneman, KP, 1985) |
| "(3) Tetrodotoxin (TTX) was tested on the anti-ChE drugs-induced responses." | 1.30 | Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs. ( Hara, T; Iwanaga, S; Makita, T; Shibata, O; Shibata, S; Sumikawa, K; Tsuda, A, 1998) |
| "The effect of streptozotocin diabetes of 4-week duration on the adrenergic motor transmission and on the nonadrenergic, noncholinergic, inhibitory transmission in the rat anococcygeus was investigated by recording contractile and relaxant activity of isolated muscle preparations taken from diabetic and age-matched control animals." | 1.28 | Effect of streptozotocin diabetes on motor and inhibitory transmission in rat anococcygeus. ( Luheshi, GN; Zar, MA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (37.04) | 18.7374 |
| 1990's | 11 (40.74) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Perez-Zoghbi, JF | 1 |
| Sajorda, DR | 1 |
| Webb, DA | 1 |
| Arnold, LA | 1 |
| Emala, CW | 1 |
| Yocum, GT | 1 |
| Zheng, GQ | 1 |
| Tong, WJ | 1 |
| Yuan, BC | 1 |
| Luo, SY | 1 |
| Zhang, YL | 1 |
| Sun, SW | 1 |
| Tokuoka, SM | 1 |
| Saiardi, A | 1 |
| Nurrish, SJ | 1 |
| Sekar, MC | 1 |
| Roufogalis, BD | 1 |
| Watson, SP | 1 |
| Downes, CP | 1 |
| Yu, P | 1 |
| Harnett, KM | 1 |
| Biancani, P | 1 |
| De Petris, G | 1 |
| Behar, J | 1 |
| Tomera, JF | 1 |
| Kukulka, SP | 1 |
| Lilford, K | 1 |
| Queiroz-Neto, A | 1 |
| Mataqueiro, MI | 1 |
| Ballejo, G | 1 |
| Seasholtz, TM | 2 |
| Gurdal, H | 1 |
| Wang, HY | 2 |
| Johnson, MD | 1 |
| Friedman, E | 2 |
| Shibata, O | 1 |
| Tsuda, A | 1 |
| Makita, T | 1 |
| Iwanaga, S | 1 |
| Hara, T | 1 |
| Shibata, S | 1 |
| Sumikawa, K | 1 |
| Cai, G | 1 |
| Tempel, GE | 1 |
| Brown, AN | 1 |
| Morinelli, TA | 1 |
| Halushka, PV | 1 |
| Cook, JA | 1 |
| Nobe, K | 1 |
| Sakai, Y | 1 |
| Maruyama, Y | 1 |
| Momose, K | 1 |
| Anderson, WM | 1 |
| Zavecz, JH | 1 |
| Tso, P | 1 |
| Luheshi, GN | 1 |
| Zar, MA | 1 |
| Abebe, W | 1 |
| MacLeod, KM | 1 |
| Baron, CB | 1 |
| Pompeo, JN | 1 |
| Azim, S | 1 |
| Cameron, NE | 1 |
| Cotter, MA | 1 |
| Robertson, S | 1 |
| Yousufzai, SY | 1 |
| Tachado, SD | 1 |
| Abdel-Latif, AA | 2 |
| Legan, E | 1 |
| Miller-Hance, WC | 1 |
| Miller, JR | 1 |
| Wells, JN | 1 |
| Stull, JT | 1 |
| Kamm, KE | 1 |
| Coburn, RF | 1 |
| Baron, C | 1 |
| Papadopoulos, MT | 1 |
| Fox, AW | 2 |
| Friedman, PA | 1 |
| Abel, PW | 2 |
| Akhtar, RA | 1 |
| Juberg, EN | 1 |
| May, JM | 1 |
| Johnson, RD | 1 |
| Minneman, KP | 1 |
| Potus, J | 1 |
| Best, L | 1 |
| Bolton, TB | 1 |
27 other studies available for inositol and Muscle Contraction
| Article | Year |
|---|---|
Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization.
Topics: Animals; Asthma; Calcium; Calcium Signaling; Flumazenil; gamma-Aminobutyric Acid; Inositol; Ligands; | 2022 |
Melatonin Attenuates Vascular Smooth Muscle Contraction Through the γ-Secretase/Notch Intracellular Domain/Myocardin Pathway.
Topics: Amyloid Precursor Protein Secretases; Animals; Calcium; Contractile Proteins; Inositol; Melatonin; M | 2022 |
The mood stabilizer valproate inhibits both inositol- and diacylglycerol-signaling pathways in Caenorhabditis elegans.
Topics: Acetylcholine; Animals; Antimanic Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; C | 2008 |
Differential effects of phenylmethanesulfonyl fluoride (PMSF) on carbachol and potassium stimulated phosphoinositide turnover and contraction in longitudinal smooth muscle of guinea pig ileum.
Topics: Animals; Carbachol; Female; Guinea Pigs; Ileum; Inositol; Kinetics; Muscle Contraction; Muscle, Smoo | 1984 |
Substance P induced hydrolysis of inositol phospholipids in guinea-pig ileum and rat hypothalamus.
Topics: Animals; Calcium; Female; Guinea Pigs; Hydrolysis; Hypothalamus; Ileum; In Vitro Techniques; Inosito | 1983 |
Interaction between signal transduction pathways contributing to gallbladder tonic contraction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calmodulin; Cats; Diglycerides; Fem | 1993 |
Cross-talk of second messengers during the systemic trauma response following burn injury: how, when, and where.
Topics: Animals; Burns; Calcium; Chromatography, Ion Exchange; Cyclic AMP; Glycerophosphates; Inositol; Inos | 1993 |
Effects of lithium and myoinositol on the rat bisected vas deferens.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol; Lithium; Ma | 1995 |
Desensitization of norepinephrine receptor function is associated with G protein uncoupling in the rat aorta.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Aorta; Cell Membrane; Glycosylation; GTP-Bind | 1997 |
Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs.
Topics: Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Dimethylphenylpiperazinium Iodi | 1998 |
Selected contribution: effects of ischemia-reperfusion on vascular contractility and alpha(1)-adrenergic-receptor signaling in the rat tail artery.
Topics: Adenylyl Cyclases; Animals; Arteries; GTP-Binding Proteins; In Vitro Techniques; Inositol; Inositol | 2001 |
Changes in vascular responsiveness to a thromboxane mimetic in endotoxin tolerance.
Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Endotoxins; Fatty Acids, Unsaturated; GTP P | 2001 |
Hyper-reactivity of diacylglycerol kinase is involved in the dysfunction of aortic smooth muscle contractility in streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Calcium; Diabetes Mellitus, Experimental; Diacylglycerol Kinase; In Vitro Techniques | 2002 |
Effects of diaphragmatic fatigue on phosphoinositide hydrolysis.
Topics: Animals; Diaphragm; In Vitro Techniques; Inositol; Muscle Contraction; Muscles; Phosphatidylinositol | 1992 |
Effect of streptozotocin diabetes on motor and inhibitory transmission in rat anococcygeus.
Topics: Aldehyde Reductase; Animals; Autonomic Nervous System Diseases; Diabetes Mellitus, Experimental; Dia | 1992 |
Enhanced arterial contractility to noradrenaline in diabetic rats is associated with increased phosphoinositide metabolism.
Topics: Animals; Aorta, Thoracic; Arteries; Blood Glucose; Diabetes Mellitus, Experimental; Inositol; Inosit | 1991 |
Inositol 1,4,5-trisphosphate compartmentalization in tracheal smooth muscle.
Topics: Animals; Atropine; Carbachol; Chromatography, High Pressure Liquid; In Vitro Techniques; Inositol; I | 1992 |
Changes in skeletal muscle contractile properties in streptozocin-induced diabetic rats and role of polyol pathway and hypoinsulinemia.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet; Hypoglycemic Agen | 1990 |
Species differences in the effects of leukotriene D4 on inositol trisphosphate accumulation, cyclic AMP formation and contraction in iris sphincter of the mammalian eye.
Topics: Animals; Cats; Cattle; Cyclic AMP; Dinoprost; Humans; In Vitro Techniques; Inositol; Inositol 1,4,5- | 1990 |
Effects of streptozotocin-induced hyperglycemia on agonist-stimulated phosphatidylinositol turnover in rat aorta.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hyperglycemia | 1989 |
Biochemical events associated with activation of smooth muscle contraction.
Topics: Animals; Calmodulin; Cattle; Electric Stimulation; In Vitro Techniques; Inositol; Inositol Phosphate | 1988 |
Phosphoinositide metabolism and metabolism-contraction coupling in rabbit aorta.
Topics: Animals; Aorta, Thoracic; In Vitro Techniques; Inositol; Kinetics; Male; Muscle Contraction; Muscle, | 1988 |
Vasopressin receptor mediated contraction and [3H]inositol metabolism in rat tail artery.
Topics: Animals; Arteries; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Muscle Contraction; Mus | 1987 |
Surgical sympathetic denervation increases alpha 1-adrenoceptor-mediated accumulation of myo-inositol trisphosphate and muscle contraction in rabbit iris dilator smooth muscle.
Topics: Adenosine Triphosphatases; Animals; Arachidonic Acid; Arachidonic Acids; Female; Inositol; Inositol | 1986 |
Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness.
Topics: Animals; Cerebral Cortex; Ethanolamines; Heart; Heart Rate; Hyperthyroidism; Hypothyroidism; In Vitr | 1985 |
[Coupled excitation and contraction in skeletal muscles: arguments in favor of a mechanism implicating inositol metabolism].
Topics: Animals; Autoradiography; Carbon Radioisotopes; Inositol; Male; Mice; Muscle Contraction; Muscles; S | 1986 |
Depolarisation of guinea-pig visceral smooth muscle causes hydrolysis of inositol phospholipids.
Topics: Animals; Female; Guinea Pigs; Hydrolysis; In Vitro Techniques; Inositol; Inositol Phosphates; Jejunu | 1986 |