Page last updated: 2024-10-19

inositol and MELAS

inositol has been researched along with MELAS in 3 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
"1H magnetic resonance spectroscopy (MRS) of the brain and (31)P MRS and saturation transfer of resting skeletal muscle were used to investigate intracellular metabolites and fluxes through the creatine kinase (CK) reaction in a patient with the syndrome of mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS)."3.71Application of NMR spectroscopy to monitoring MELAS treatment: a case report. ( Hilbich, T; Kurlemann, G; Möller, HE; Schuierer, G; Wiedermann, D, 2002)
"Six patients with MELAS (age 28 ± 13 years, 3 [50%] female) and 17 with MSS (age 45 ± 11 years, 7 [41%] female) and 39 sex- and age-matched healthy controls (HC) were enrolled."1.62Brain MRS correlates with mitochondrial dysfunction biomarkers in MELAS-associated mtDNA mutations. ( Amore, G; Bianchini, C; Caporali, L; Carelli, V; Cortesi, I; Di Vito, L; Evangelisti, S; Gramegna, LL; La Morgia, C; Liguori, R; Lodi, R; Manners, DN; Maresca, A; Talozzi, L; Testa, C; Tonon, C; Valentino, ML, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Gramegna, LL1
Evangelisti, S1
Di Vito, L1
La Morgia, C1
Maresca, A1
Caporali, L1
Amore, G1
Talozzi, L1
Bianchini, C1
Testa, C1
Manners, DN1
Cortesi, I1
Valentino, ML1
Liguori, R1
Carelli, V1
Tonon, C1
Lodi, R1
Wilichowski, E1
Pouwels, PJ1
Frahm, J1
Hanefeld, F1
Möller, HE1
Wiedermann, D1
Kurlemann, G1
Hilbich, T1
Schuierer, G1

Other Studies

3 other studies available for inositol and MELAS

ArticleYear
Brain MRS correlates with mitochondrial dysfunction biomarkers in MELAS-associated mtDNA mutations.
    Annals of clinical and translational neurology, 2021, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Cerebellum; Cerebral Cortex; Choline; DNA, Mitoc

2021
Quantitative proton magnetic resonance spectroscopy of cerebral metabolic disturbances in patients with MELAS.
    Neuropediatrics, 1999, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Brain; Child; Disease Progression; Female; Humans; Inositol; Magnetic Resonance S

1999
Application of NMR spectroscopy to monitoring MELAS treatment: a case report.
    Muscle & nerve, 2002, Volume: 25, Issue:4

    Topics: Adolescent; Aspartic Acid; Brain; Creatine; Female; Glutamic Acid; Humans; Inositol; Lactic Acid; Ma

2002