inositol has been researched along with MELAS in 3 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1H magnetic resonance spectroscopy (MRS) of the brain and (31)P MRS and saturation transfer of resting skeletal muscle were used to investigate intracellular metabolites and fluxes through the creatine kinase (CK) reaction in a patient with the syndrome of mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS)." | 3.71 | Application of NMR spectroscopy to monitoring MELAS treatment: a case report. ( Hilbich, T; Kurlemann, G; Möller, HE; Schuierer, G; Wiedermann, D, 2002) |
| "Six patients with MELAS (age 28 ± 13 years, 3 [50%] female) and 17 with MSS (age 45 ± 11 years, 7 [41%] female) and 39 sex- and age-matched healthy controls (HC) were enrolled." | 1.62 | Brain MRS correlates with mitochondrial dysfunction biomarkers in MELAS-associated mtDNA mutations. ( Amore, G; Bianchini, C; Caporali, L; Carelli, V; Cortesi, I; Di Vito, L; Evangelisti, S; Gramegna, LL; La Morgia, C; Liguori, R; Lodi, R; Manners, DN; Maresca, A; Talozzi, L; Testa, C; Tonon, C; Valentino, ML, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gramegna, LL | 1 |
| Evangelisti, S | 1 |
| Di Vito, L | 1 |
| La Morgia, C | 1 |
| Maresca, A | 1 |
| Caporali, L | 1 |
| Amore, G | 1 |
| Talozzi, L | 1 |
| Bianchini, C | 1 |
| Testa, C | 1 |
| Manners, DN | 1 |
| Cortesi, I | 1 |
| Valentino, ML | 1 |
| Liguori, R | 1 |
| Carelli, V | 1 |
| Tonon, C | 1 |
| Lodi, R | 1 |
| Wilichowski, E | 1 |
| Pouwels, PJ | 1 |
| Frahm, J | 1 |
| Hanefeld, F | 1 |
| Möller, HE | 1 |
| Wiedermann, D | 1 |
| Kurlemann, G | 1 |
| Hilbich, T | 1 |
| Schuierer, G | 1 |
3 other studies available for inositol and MELAS
| Article | Year |
|---|---|
Brain MRS correlates with mitochondrial dysfunction biomarkers in MELAS-associated mtDNA mutations.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Cerebellum; Cerebral Cortex; Choline; DNA, Mitoc | 2021 |
Quantitative proton magnetic resonance spectroscopy of cerebral metabolic disturbances in patients with MELAS.
Topics: Adolescent; Adult; Brain; Child; Disease Progression; Female; Humans; Inositol; Magnetic Resonance S | 1999 |
Application of NMR spectroscopy to monitoring MELAS treatment: a case report.
Topics: Adolescent; Aspartic Acid; Brain; Creatine; Female; Glutamic Acid; Humans; Inositol; Lactic Acid; Ma | 2002 |