inositol has been researched along with Leukodystrophy, Globoid Cell in 3 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Leukodystrophy, Globoid Cell: An autosomal recessive metabolic disorder caused by a deficiency of GALACTOSYLCERAMIDASE leading to intralysosomal accumulation of galactolipids such as GALACTOSYLCERAMIDES and PSYCHOSINE. It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of MYELIN disrupts normal conduction of nerve impulses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Krabbe disease (globoid cell leukodystrophy [GLD]) is an autosomal recessive lysosomal disorder affecting the central and peripheral nervous system." | 2.71 | Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease. ( Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Rusch, O; Wilken, B, 2003) |
| "We present a case of infantile onset Krabbe disease with prolonged survival, initial intracranial optic nerves and optic chiasm hypertrophy, and serial changes on cranial magnetic resonance imaging and magnetic resonance spectroscopy." | 1.38 | Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease. ( Bunge, M; Mhanni, AA; Ryner, L; Salman, MS; Udow, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Udow, S | 1 |
| Bunge, M | 1 |
| Ryner, L | 1 |
| Mhanni, AA | 1 |
| Salman, MS | 1 |
| Brockmann, K | 1 |
| Dechent, P | 1 |
| Wilken, B | 1 |
| Rusch, O | 1 |
| Frahm, J | 1 |
| Hanefeld, F | 1 |
| Vanier, MT | 1 |
| Svennerholm, L | 1 |
1 trial available for inositol and Leukodystrophy, Globoid Cell
| Article | Year |
|---|---|
Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Child; Child, Preschool; Choline; Creatinine; Dipeptides | 2003 |
2 other studies available for inositol and Leukodystrophy, Globoid Cell
| Article | Year |
|---|---|
Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease.
Topics: Anticonvulsants; Aspartic Acid; Brain Chemistry; Choline; Combined Modality Therapy; Creatine; DNA M | 2012 |
Chemical pathology of Krabbe's disease. I. Lipid composition and fatty acid patterns of phosphoglycerides in brain.
Topics: Brain Chemistry; Cerebral Cortex; Cerebrosides; Child, Preschool; Cholesterol; Choline; Ethanolamine | 1974 |