Page last updated: 2024-10-19

inositol and Koch's Disease

inositol has been researched along with Koch's Disease in 11 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
"Inositol is utilized by Mycobacterium tuberculosis in the production of its major thiol and of essential cell wall lipoglycans."3.72The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence. ( Av-Gay, Y; Bancroft, GJ; Daffe, M; Dinadayala, P; Kendall, SL; McAlister, MS; McDonald, NQ; Movahedzadeh, F; Murray-Rust, J; Norman, RA; Rison, SC; Russell, DG; Smith, DA; Stoker, NG, 2004)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sao Emani, C3
Williams, MJ2
Van Helden, PD1
Taylor, MJC1
Wiid, IJ3
Baker, B3
Negri, A1
Javidnia, P1
Mu, R1
Zhang, X1
Vendome, J1
Gold, B1
Roberts, J1
Barman, D1
Ioerger, T1
Sacchettini, JC1
Jiang, X1
Burns-Huang, K1
Warrier, T1
Ling, Y1
Warren, JD1
Oren, DA1
Beuming, T1
Wang, H1
Wu, J1
Li, H1
Rhee, KY1
Nathan, CF1
Liu, G1
Somersan-Karakaya, S1
Gallant, JL1
Bhaskar, A1
Chawla, M1
Mehta, M1
Parikh, P1
Chandra, P1
Bhave, D1
Kumar, D1
Carroll, KS1
Singh, A1
Schiebler, M1
Brown, K1
Hegyi, K1
Newton, SM1
Renna, M1
Hepburn, L1
Klapholz, C1
Coulter, S1
Obregón-Henao, A1
Henao Tamayo, M1
Basaraba, R1
Kampmann, B1
Henry, KM1
Burgon, J1
Renshaw, SA1
Fleming, A1
Kay, RR1
Anderson, KE1
Hawkins, PT1
Ordway, DJ1
Rubinsztein, DC1
Floto, RA1
SCHAEFER, EL1
GREUEL, H1
Movahedzadeh, F1
Smith, DA1
Norman, RA1
Dinadayala, P1
Murray-Rust, J1
Russell, DG1
Kendall, SL1
Rison, SC1
McAlister, MS1
Bancroft, GJ1
McDonald, NQ1
Daffe, M1
Av-Gay, Y1
Stoker, NG1
Gilleron, M1
Lindner, B1
Puzo, G1
Sodikov, ES1
Gapon'ko, LA1
Kruchakova, FA1

Reviews

1 review available for inositol and Koch's Disease

ArticleYear
The role of low molecular weight thiols in Mycobacterium tuberculosis.
    Tuberculosis (Edinburgh, Scotland), 2019, Volume: 116

    Topics: Animals; Antitubercular Agents; Cysteine; Dipeptides; Enzyme Inhibitors; Enzymes; Ergothioneine; Gly

2019

Other Studies

10 other studies available for inositol and Koch's Disease

ArticleYear
Gamma-glutamylcysteine protects ergothioneine-deficient Mycobacterium tuberculosis mutants against oxidative and nitrosative stress.
    Biochemical and biophysical research communications, 2018, 01-01, Volume: 495, Issue:1

    Topics: Biosynthetic Pathways; Cysteine; Dipeptides; Ergothioneine; Gene Deletion; Glycopeptides; Humans; In

2018
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
    ACS infectious diseases, 2018, 05-11, Volume: 4, Issue:5

    Topics: Animals; Bacterial Proteins; Binding Sites; Cysteine; Disease Models, Animal; Enzyme Activation; Fem

2018
The functional interplay of low molecular weight thiols in Mycobacterium tuberculosis.
    Journal of biomedical science, 2018, Jul-12, Volume: 25, Issue:1

    Topics: Animals; Cysteine; Dipeptides; Ergothioneine; Glycopeptides; Humans; Inositol; Mice; Molecular Weigh

2018
Reengineering redox sensitive GFP to measure mycothiol redox potential of Mycobacterium tuberculosis during infection.
    PLoS pathogens, 2014, Volume: 10, Issue:1

    Topics: Cell Line, Tumor; Cysteine; Glycopeptides; Green Fluorescent Proteins; Humans; Inositol; Macrophages

2014
Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion.
    EMBO molecular medicine, 2015, Volume: 7, Issue:2

    Topics: Animals; Anticonvulsants; Antitubercular Agents; Autophagy; Carbamazepine; Cell Line; Disease Models

2015
[The effect of sodium phyate on guinea pig tuberculosis].
    Der Tuberkulosearzt, 1961, Volume: 15

    Topics: Guinea Pigs; Inositol; Sodium; Sodium, Dietary; Tuberculosis

1961
The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence.
    Molecular microbiology, 2004, Volume: 51, Issue:4

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Disaccharides; DNA Mutational Analysis; Gene

2004
MS/MS approach for characterization of the fatty acid distribution on mycobacterial phosphatidyl-myo-inositol mannosides.
    Analytical chemistry, 2006, Dec-15, Volume: 78, Issue:24

    Topics: Acylation; Antigens, CD1; Binding Sites; Fatty Acids; Glycerol; Immunologic Factors; Inositol; Ligan

2006
[Effect of combinations of trace elements and vitamins in inositol metabolism and the morphohistochemical indices in the isoniazid treatment of experimental tuberculosis].
    Problemy tuberkuleza, 1976, Issue:7

    Topics: Animals; Copper; Drug Therapy, Combination; Inositol; Isoniazid; Liver; Male; Rabbits; Trace Element

1976
[Changes in the biotin and inositol content of tissues of healthy and tubercular guinea pigs during administration of antibacterial preparations].
    Problemy tuberkuleza, 1970, Volume: 48, Issue:7

    Topics: Animals; Antitubercular Agents; Biotin; Brain; Guinea Pigs; Inositol; Liver; Lung; Muscles; Spleen;

1970