inositol has been researched along with Kidney Failure, Chronic in 30 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Teneligliptin is a novel DPP-4 inhibitor in development for treating type 2 diabetes mellitus that does not require dose adjustment for diabetic patients with end-stage renal disease; however, it had not been known whether or not teneligliptin is safe or potent in dialysis patients." | 2.79 | Safety and efficacy of teneligliptin: a novel DPP-4 inhibitor for hemodialysis patients with type 2 diabetes. ( Kosaka, T; Kuwahara, Y; Nakamura, K; Otsuki, H; Shimomura, F; Tsukamoto, T, 2014) |
| "In a series of patients with chronic renal failure managed conservatively, the rise in the plasma-myo-inositol (myoinositol) concentration has been found to be related to depression of sural-nerve conduction velocity." | 1.26 | Plasma-myoinositol concentrations in uraemic neuropathy. ( Reznek, RH; Salway, JG; Thomas, PK, 1977) |
| "In 12 patients with chronic renal failure who received kidney transplants from either cadavers (6) or related living donors (6), rapid improvement in median sensory and motor nerve conduction velocities (NCVs) was observed within a few days after transplantation." | 1.26 | Rapid improvement in nerve conduction velocity following renal transplantation. ( Clements, RS; Diethelm, AG; Lee, YW; Oh, SJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (76.67) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lepping, RJ | 1 |
| Montgomery, RN | 1 |
| Sharma, P | 1 |
| Mahnken, JD | 1 |
| Vidoni, ED | 1 |
| Choi, IY | 1 |
| Sarnak, MJ | 1 |
| Brooks, WM | 1 |
| Burns, JM | 1 |
| Gupta, A | 1 |
| Ferrer, MD | 1 |
| Ketteler, M | 1 |
| Tur, F | 1 |
| Tur, E | 1 |
| Isern, B | 1 |
| Salcedo, C | 1 |
| Joubert, PH | 1 |
| Behets, GJ | 1 |
| Neven, E | 1 |
| D'Haese, PC | 1 |
| Perelló, J | 1 |
| Otsuki, H | 1 |
| Kosaka, T | 1 |
| Nakamura, K | 1 |
| Shimomura, F | 1 |
| Kuwahara, Y | 1 |
| Tsukamoto, T | 1 |
| Nakashima, S | 1 |
| Gulak, PV | 1 |
| Navarro, J | 1 |
| Contreras, P | 1 |
| Touraine, JL | 1 |
| Freyria, AM | 1 |
| Later, R | 1 |
| Traeger, J | 1 |
| Delbono, O | 1 |
| Losavio, AS | 1 |
| Kotsias, BA | 1 |
| Obejero Paz, CA | 1 |
| Muchnik, S | 1 |
| Kuzuhara, K | 2 |
| Inou, T | 1 |
| Wada, E | 1 |
| Tsumita, T | 1 |
| Bartnicki, P | 1 |
| Luciak, M | 1 |
| Zbróg, Z | 1 |
| Tchórzewski, H | 1 |
| Geissler, A | 1 |
| Fründ, R | 1 |
| Kohler, S | 1 |
| Eichhorn, HM | 1 |
| Krämer, BK | 1 |
| Feuerbach, S | 1 |
| Reznek, RH | 1 |
| Salway, JG | 1 |
| Thomas, PK | 1 |
| Oh, SJ | 1 |
| Clements, RS | 3 |
| Lee, YW | 1 |
| Diethelm, AG | 2 |
| Walasek, L | 5 |
| Lutz, W | 4 |
| Trznadel, K | 5 |
| Kidawa, Z | 1 |
| Waldemar, L | 1 |
| Servo, C | 2 |
| Palo, J | 1 |
| Pitkänen, E | 2 |
| Gaszyński, W | 1 |
| Bardy, A | 1 |
| Pasternack, A | 1 |
| Kinoshita, M | 1 |
| Isoda, K | 1 |
| Hattori, H | 1 |
| Okano, Y | 1 |
| Nozawa, Y | 1 |
| Kudo, S | 1 |
| Troyer, DA | 1 |
| Schwertz, DW | 1 |
| Kreisberg, JI | 1 |
| Venkatachalam, MA | 1 |
| Kaniu, H | 1 |
| Tsuji, H | 1 |
| Furukawa, K | 1 |
| Miura, M | 1 |
| Hara, S | 1 |
| Suzuki, Y | 1 |
| Nihei, H | 1 |
| Akagi, K | 1 |
| Uchigata, M | 1 |
| Onishi, S | 1 |
| Kawasaki, T | 1 |
| Hamada, K | 1 |
| Powell, D | 1 |
| Bergstrom, J | 1 |
| Dzurik, R | 1 |
| Gulyassy, P | 1 |
| Lockwood, D | 1 |
| Phillips, L | 1 |
| Bednorz, R | 1 |
| DeJesus, PV | 1 |
| Winegrad, AI | 1 |
| Friis, T | 1 |
| Hahnemann, S | 1 |
| Weeke, E | 1 |
| Irnell, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cognitive Impairment and Imaging Correlates in End Stage Renal Disease[NCT01883349] | 140 participants (Anticipated) | Observational | 2013-03-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for inositol and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Inositol].
Topics: Animals; Atrophy; Biomarkers; Brain; Chromatography, Gas; Diabetic Neuropathies; Gas Chromatography- | 2004 |
[Physiological aspects of phosphoinositide metabolism].
Topics: Animals; Calcium; Cell Membrane Permeability; Cyclization; Diabetes Mellitus; Diabetes Mellitus, Exp | 1981 |
Are 'middle molecules' responsible for toxic phenomena in chronic renal failure?
Topics: Anemia; Animals; Humans; Immunity, Cellular; Inositol; Kidney Failure, Chronic; Neurotoxins; Parathy | 1982 |
[Neuromuscular disorders in chronic renal failure].
Topics: Animals; Dogs; Electromyography; Humans; Inositol; Kidney Failure, Chronic; Muscles; Neuromuscular D | 1983 |
Inositol phospholipid metabolism in the kidney.
Topics: Adenosine Triphosphatases; Aminoglycosides; Animals; Anti-Bacterial Agents; Biological Transport; Ca | 1986 |
Toxins and inhibitors in chronic renal failure.
Topics: Amines; Binding, Competitive; Child; Guanidines; Humans; Inositol; Insulin; Insulin Antagonists; Kid | 1986 |
2 trials available for inositol and Kidney Failure, Chronic
| Article | Year |
|---|---|
Safety and efficacy of teneligliptin: a novel DPP-4 inhibitor for hemodialysis patients with type 2 diabetes.
Topics: Adamantane; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Fema | 2014 |
[Changes in the serum calcium and the serum phosphorus in persons with uremia and in normal persons after administration of sodium phytate- and aluminum hydroxide].
Topics: Calcium; Clinical Trials as Topic; Female; Humans; Hydroxides; Inositol; Kidney Failure, Chronic; Ki | 1967 |
22 other studies available for inositol and Kidney Failure, Chronic
| Article | Year |
|---|---|
Normalization of Cerebral Blood Flow, Neurochemicals, and White Matter Integrity after Kidney Transplantation.
Topics: Adult; Aged; Case-Control Studies; Cerebrovascular Circulation; Choline; Cognition; Cognitive Dysfun | 2021 |
Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification.
Topics: Animals; Calcinosis; Cardiovascular Diseases; Cholecalciferol; Disease Models, Animal; Disease Progr | 2018 |
[Free myo-inositol levels in blood and renal function (author's transl)].
Topics: Adult; Female; Graft Rejection; Humans; Inositol; Kidney; Kidney Failure, Chronic; Kidney Transplant | 1980 |
Myoinositol incorporation into lymphocytes of chronic renal failure patients is impaired.
Topics: Adult; Aluminum; Cell Membrane; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone | 1995 |
Cerebral metabolite patterns in dialysis patients: evaluation with H-1 MR spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Glycine; Humans; Inositol; Kidney Failure, C | 1995 |
Plasma-myoinositol concentrations in uraemic neuropathy.
Topics: Action Potentials; Humans; Inositol; Kidney Failure, Chronic; Motor Neurons; Muscles; Neural Conduct | 1977 |
Rapid improvement in nerve conduction velocity following renal transplantation.
Topics: Adolescent; Adult; Child; Female; Humans; Inositol; Kidney Failure, Chronic; Kidney Transplantation; | 1978 |
The metabolism of myo-inositol by the human kidney.
Topics: Adolescent; Adult; Blood Urea Nitrogen; Creatinine; Female; Humans; Inositol; Kidney; Kidney Failure | 1979 |
[Phosphatidylinositol and myoinositol concentration in the erythrocytes and plasma in chronic renal insufficiency].
Topics: Adult; Erythrocytes; Female; Humans; Inositol; Kidney Failure, Chronic; Male; Middle Aged; Phosphati | 1979 |
Comparative studies on the effect of hemoperfusion and hemodialysis on the elimination of some uremic toxins.
Topics: Blood Platelets; Calcium; Cell Count; Creatinine; Fibrinogen; Hemoperfusion; Humans; Inositol; Kidne | 1978 |
[Relationship between serum myoinositol and serum lipid concentrations in patients with chronic renal failure].
Topics: Adult; Aged; Female; Humans; Inositol; Kidney Failure, Chronic; Lipids; Male; Middle Aged | 1977 |
The dynamics of serum myoinositol concentration changes during haemodialysis and peritoneal dialysis.
Topics: Adult; Creatinine; Female; Humans; Inositol; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal | 1977 |
Polyols in the cerebrospinal fluid and plasma of neurological, diabetic and uraemic patients.
Topics: Diabetes Mellitus; Humans; Inositol; Ischemic Attack, Transient; Kidney Failure, Chronic; Mannitol; | 1977 |
Myoinositol clearance from the serum after intravenous loading dose (experimental and clinical investigations)
Topics: Adult; Animals; Female; Glomerulonephritis; Humans; Injections, Intravenous; Inositol; Kidney; Kidne | 1977 |
Plasma, red cell and cerebrospinal fluid concentrations of myoinositol in patients with severe chronic renal failure.
Topics: Creatinine; Erythrocytes; Humans; Inositol; Kidney Failure, Chronic; Renal Dialysis | 1976 |
[Autonomic nerve dysfunction on chronic renal failure].
Topics: Autonomic Nervous System Diseases; Carnitine; Humans; Hyperparathyroidism, Secondary; Inositol; Kidn | 1992 |
[Significance of inositol analysis in clinical tests].
Topics: Animals; Biological Assay; Chromatography, Gas; Diabetes Mellitus; Humans; Inositol; Kidney Failure, | 1989 |
[Relationship between serum myo-inositol and peripheral neuropathy in patients with chronic renal failure].
Topics: Creatinine; Humans; Inositol; Kidney Failure, Chronic; Neural Conduction; Peripheral Nervous System | 1986 |
Experimental studies on pathogenesis and progression of uremic neuropathy in rats. II. Is plasma myoinositol a uremic neurotoxin?
Topics: Animals; Disease Models, Animal; Inositol; Kidney Failure, Chronic; Male; Nervous System Diseases; N | 1986 |
[Myoinositol level in the serum and urine of children with renal failure during conservative treatment and treatment with peritoneal dialysis].
Topics: Acute Kidney Injury; Adolescent; Child; Child, Preschool; Humans; Infant; Inositol; Kidney Failure, | 1986 |
Raised plasma-myoinositol levels in uraemia and experimental neuropathy.
Topics: Administration, Oral; Animals; Blood Urea Nitrogen; Chromatography, Gas; Evoked Potentials; Fasting; | 1973 |
Metastatic calcification of soft tissue on overdosage of vitamin D.
Topics: Adrenal Cortex Hormones; Adult; Calcium; Diet Therapy; Ergocalciferols; Female; Goiter; Humans; Hype | 1969 |