Page last updated: 2024-10-19

inositol and Hypoxia

inositol has been researched along with Hypoxia in 18 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
" The aim of the present study was to characterize the turnover rate of inositol phosphates (InsPs) and phosphoinositides (PIs) and their modifications by hypoxia in the rabbit CB in vitro."3.70Hypoxia inhibits the synthesis of phosphoinositides in the rabbit carotid body. ( Cachero, MT; González, C; Rigual, R; Rocher, A, 1999)
"We examined the effects of in vitro anoxia and in vivo hypoxia (8% O2/92% N2) on norepinephrine (NE)- and carbachol-stimulated phosphoinositide (PI) turnover in rat brain slices."3.67Effects of oxygen depletion on norepinephrine- and carbachol-stimulated phosphoinositide turnover in rat brain slices. ( Fujiwara, M; Kameyama, M; Ninomiya, H; Taniguchi, T, 1989)
"Myo-inositol (Myo-ins) is a marker of neuroglial cells, being present in the astrocytes of brain tissue, but also functions as an osmolyte."1.39Myo-inositol metabolism in appropriately grown and growth-restricted fetuses: a proton magnetic resonance spectroscopy study. ( Allsop, JM; Damodaram, MS; Kumar, S; Mcguinness, A; Patel, A; Rutherford, MA; Story, L; Supramaniam, V; Wylezinska, M, 2013)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's5 (27.78)18.2507
2000's2 (11.11)29.6817
2010's2 (11.11)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Correia, SC1
Alves, MG1
Oliveira, PF1
Casadesus, G1
LaManna, J1
Perry, G1
Moreira, PI1
Guo, X1
Meng, Y1
Wang, Y1
Nan, S1
Lu, Y1
Lu, D1
Yin, Y1
Story, L1
Damodaram, MS1
Supramaniam, V1
Allsop, JM1
Mcguinness, A1
Patel, A1
Wylezinska, M1
Kumar, S1
Rutherford, MA1
Bogdanova, OV1
Abdullah, O1
Kanekar, S1
Bogdanov, VB1
Prescot, AP1
Renshaw, PF1
Gardocki, ME1
Lopes, JM1
Cameron, NE1
Cotter, MA1
Maxfield, EK1
Hersey, K1
Hu, ZY1
Zhang, JP1
Rhodes, PG1
Sun, GY1
Rigual, R1
Cachero, MT1
Rocher, A1
González, C1
Van Cappellen Van Walsum, AM1
Jongsma, HW1
Wevers, RA1
Nijhuis, JG1
Crevels, J1
Engelke, UF1
De Abreu, RA1
Moolenaar, SH1
Oeseburg, B1
Nijland, R1
Daumerie-Goffinet, C1
Lambert, AE1
Willars, GB1
Calcutt, NA1
Tomlinson, DR2
Smith, WJ1
Diemel, LT1
Leach, RM1
Huang, HM1
Gibson, GE1
Ninomiya, H1
Taniguchi, T1
Fujiwara, M1
Kameyama, M1
Low, PA2
Schmelzer, JD1
Ward, KK1
Yao, JK1
Macfarlane, CM1
Duhm, J1
Gerlach, E1

Reviews

1 review available for inositol and Hypoxia

ArticleYear
[Diabetic microangiopathies].
    Acta clinica Belgica, 1978, Volume: 33, Issue:4

    Topics: Basement Membrane; Blood Viscosity; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies

1978

Other Studies

17 other studies available for inositol and Hypoxia

ArticleYear
Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria.
    Antioxidants & redox signaling, 2022, Volume: 37, Issue:10-12

    Topics: Alzheimer Disease; Animals; Disease Models, Animal; DNA, Mitochondrial; Glial Fibrillary Acidic Prot

2022
Mice lacking 1,4,5-triphosphate inositol type III receptor demonstrate inhibition of hypoxic pulmonary hypertension.
    Biochemical and biophysical research communications, 2022, 11-12, Volume: 629

    Topics: Animals; Calcium; Cell Proliferation; Endothelial Cells; Hypertension, Pulmonary; Hypoxia; Inositol;

2022
Myo-inositol metabolism in appropriately grown and growth-restricted fetuses: a proton magnetic resonance spectroscopy study.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 170, Issue:1

    Topics: Astrocytes; Brain; Case-Control Studies; Creatine; Female; Fetal Growth Retardation; Fetus; Humans;

2013
Neurochemical alterations in frontal cortex of the rat after one week of hypobaric hypoxia.
    Behavioural brain research, 2014, Apr-15, Volume: 263

    Topics: Alanine; Altitude; Animals; Corpus Striatum; Creatine; Depressive Disorder; Female; Frontal Lobe; Gl

2014
Expression of the yeast PIS1 gene requires multiple regulatory elements including a Rox1p binding site.
    The Journal of biological chemistry, 2003, Oct-03, Volume: 278, Issue:40

    Topics: Base Sequence; Binding Sites; Carbon; Chloramphenicol O-Acetyltransferase; Choline; Chromatography,

2003
Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats.
    Diabetologia, 1993, Volume: 36, Issue:4

    Topics: Action Potentials; Animals; Butylated Hydroxytoluene; Capillaries; Diabetes Mellitus, Experimental;

1993
In utero hypoxic ischemia decreases the cholinergic agonist-stimulated poly-phosphoinositide turnover in the developing rat brain.
    Neurochemical research, 1995, Volume: 20, Issue:12

    Topics: Animals; Brain; Carbachol; Constriction; Female; Hypoxia; Inositol; Ischemia; Lithium Chloride; Para

1995
Hypoxia inhibits the synthesis of phosphoinositides in the rabbit carotid body.
    Pflugers Archiv : European journal of physiology, 1999, Volume: 437, Issue:6

    Topics: Animals; Carotid Body; Hypoxia; Inositol; Inositol 1,4,5-Trisphosphate; Lithium Chloride; Phosphatid

1999
1H-NMR spectroscopy of cerebrospinal fluid of fetal sheep during hypoxia-induced acidemia and recovery.
    Pediatric research, 2002, Volume: 52, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Choline; Citric Acid; Creatinine; Energy Metabolism; Femal

2002
Nerve conduction velocity and axonal transport of 6-phosphofructokinase activity in galactose-fed rats.
    Journal of the neurological sciences, 1991, Volume: 104, Issue:1

    Topics: Aldehyde Reductase; Animals; Axonal Transport; Blood Glucose; Body Weight; Carbohydrate Metabolism;

1991
Central hypoxaemia in rats provokes neurological defects similar to those seen in experimental diabetes mellitus: evidence for a partial role of endoneurial hypoxia in diabetic neuropathy.
    Neuroscience, 1991, Volume: 45, Issue:2

    Topics: Animals; Diabetic Neuropathies; Glucose; Hypoxia; Inositol; Male; Nerve Tissue Proteins; Neural Cond

1991
Phosphatidylinositol metabolism during in vitro hypoxia.
    Journal of neurochemistry, 1989, Volume: 52, Issue:3

    Topics: Animals; Calcium; Cerebral Cortex; Chlorides; Hypoxia; Inositol; Lithium; Lithium Chloride; Male; Ph

1989
Effects of oxygen depletion on norepinephrine- and carbachol-stimulated phosphoinositide turnover in rat brain slices.
    Journal of neurochemistry, 1989, Volume: 53, Issue:1

    Topics: Animals; Brain; Carbachol; Hypoxia; In Vitro Techniques; Inositol; Inositol Phosphates; Norepinephri

1989
Experimental chronic hypoxic neuropathy: relevance to diabetic neuropathy.
    The American journal of physiology, 1986, Volume: 250, Issue:1 Pt 1

    Topics: Animals; Diabetic Neuropathies; Disease Models, Animal; Electrophysiology; Glycated Hemoglobin; Hexo

1986
Recent advances in the pathogenesis of diabetic neuropathy.
    Muscle & nerve, 1987, Volume: 10, Issue:2

    Topics: Animals; Capillaries; Diabetic Neuropathies; Humans; Hypoxia; Inositol; Ischemia; Neural Conduction;

1987
Secondary changes in diabetes mellitus with particular reference to retinopathy and neuropathy.
    Medical hypotheses, 1985, Volume: 17, Issue:4

    Topics: Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Glucose; Humans; Hypoxia; Inositol

1985
On the mechanisms of the hypoxia-induced increase of 2,3-diphosphoglycerate in erythrocytes. Studies on rat erythrocytes in vivo and on human erythrocytes in vitro.
    Pflugers Archiv : European journal of physiology, 1971, Volume: 326, Issue:3

    Topics: Adaptation, Biological; Altitude; Anemia; Animals; Columbidae; Erythrocytes; Glycerophosphates; Glyc

1971