inositol has been researched along with Hyponatremia in 12 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Hyponatremia: Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was recently demonstrated that renal failure and exogenous urea prevent myelinolysis induced by rapid correction of experimental hyponatremia." | 7.71 | Rapid (24-hour) reaccumulation of brain organic osmolytes (particularly myo-inositol) in azotemic rats after correction of chronic hyponatremia. ( Decaux, G; Schroöeder, B; Silver, S; Soupart, A; Sterns, R, 2002) |
| "Myoinositol-treated animals had significantly fewer demyelinating lesions than mannitol (2." | 5.33 | Myoinositol administration improves survival and reduces myelinolysis after rapid correction of chronic hyponatremia in rats. ( Rojiani, AM; Schroeder, BM; Silver, SM; Sterns, RH, 2006) |
| "It was recently demonstrated that renal failure and exogenous urea prevent myelinolysis induced by rapid correction of experimental hyponatremia." | 3.71 | Rapid (24-hour) reaccumulation of brain organic osmolytes (particularly myo-inositol) in azotemic rats after correction of chronic hyponatremia. ( Decaux, G; Schroöeder, B; Silver, S; Soupart, A; Sterns, R, 2002) |
| "To clarify the role of the sugar polyols, sorbitol and myo-inositol, in cerebral cell volume regulation, we studied the effect of sorbinil, an inhibitor of aldose and aldehyde reductase, on the size of the cerebral water compartments in rats with hypernatremia, hyponatremia and normonatremia." | 3.68 | The role of polyols in cerebral cell volume regulation in hypernatremic and hyponatremic states. ( Futterweit, S; Hammer, E; Oates, P; Siegel, TW; Trachtman, H, 1991) |
| "Hyponatremia has a complex, non-linear relationship with brain Glx and mI, cognition and HRQOL." | 1.39 | Differential impact of hyponatremia and hepatic encephalopathy on health-related quality of life and brain metabolite abnormalities in cirrhosis. ( Ahluwalia, V; Bajaj, JS; Bouneva, I; Fuchs, M; Gilles, H; Heuman, DM; Kraft, KA; Luketic, V; Puri, P; Sanyal, AJ; Sterling, RK; Stravitz, RT; Thacker, L; Wade, JB, 2013) |
| "Myo-inositol levels were strongly decreased already at 3h after treatment with NH4Cl; other intracellular osmolytes, such as hypotaurine and choline-containing compounds were also decreased, along with a concomitant increase of both the total concentration and the amount of newly synthesized glutamine, alanine, and glutathione." | 1.33 | Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response. ( Leibfritz, D; Zwingmann, C, 2005) |
| "Myoinositol-treated animals had significantly fewer demyelinating lesions than mannitol (2." | 1.33 | Myoinositol administration improves survival and reduces myelinolysis after rapid correction of chronic hyponatremia in rats. ( Rojiani, AM; Schroeder, BM; Silver, SM; Sterns, RH, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Asaki, Y | 1 |
| Murofushi, Y | 1 |
| Yasukawa, K | 1 |
| Hara, M | 1 |
| Takanashi, JI | 1 |
| Ahluwalia, V | 1 |
| Wade, JB | 1 |
| Thacker, L | 1 |
| Kraft, KA | 1 |
| Sterling, RK | 1 |
| Stravitz, RT | 1 |
| Fuchs, M | 1 |
| Bouneva, I | 1 |
| Puri, P | 1 |
| Luketic, V | 1 |
| Sanyal, AJ | 1 |
| Gilles, H | 1 |
| Heuman, DM | 1 |
| Bajaj, JS | 1 |
| Zwingmann, C | 1 |
| Leibfritz, D | 1 |
| Silver, SM | 3 |
| Schroeder, BM | 2 |
| Sterns, RH | 4 |
| Rojiani, AM | 1 |
| Videen, JS | 1 |
| Michaelis, T | 1 |
| Pinto, P | 1 |
| Ross, BD | 1 |
| Bersudsky, Y | 1 |
| Kaplan, Z | 1 |
| Shapiro, Y | 1 |
| Agam, G | 1 |
| Kofman, O | 1 |
| Belmaker, RH | 1 |
| Baer, J | 1 |
| Ebersol, S | 1 |
| Thomas, D | 1 |
| Lohr, JW | 1 |
| Kamm, DE | 1 |
| Soupart, A | 1 |
| Silver, S | 1 |
| Schroöeder, B | 1 |
| Sterns, R | 1 |
| Decaux, G | 1 |
| Trachtman, H | 1 |
| Futterweit, S | 1 |
| Hammer, E | 1 |
| Siegel, TW | 1 |
| Oates, P | 1 |
| Thurston, JH | 1 |
| Sherman, WR | 1 |
| Hauhart, RE | 1 |
| Kloepper, RF | 1 |
1 review available for inositol and Hyponatremia
| Article | Year |
|---|---|
Brain volume regulation in response to hypo-osmolality and its correction.
Topics: Acute Disease; Animals; Brain; Brain Edema; Chronic Disease; Demyelinating Diseases; Humans; Hyponat | 2006 |
1 trial available for inositol and Hyponatremia
| Article | Year |
|---|---|
Human cerebral osmolytes during chronic hyponatremia. A proton magnetic resonance spectroscopy study.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Creatine; Female; Follow-Up Studies; Humans; | 1995 |
10 other studies available for inositol and Hyponatremia
| Article | Year |
|---|---|
Neurochemistry of hyponatremic encephalopathy evaluated by MR spectroscopy.
Topics: Aspartic Acid; Child; Creatine; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Hyponatrem | 2020 |
Differential impact of hyponatremia and hepatic encephalopathy on health-related quality of life and brain metabolite abnormalities in cirrhosis.
Topics: Brain; Cognition; Cognition Disorders; Diuretics; Female; Glutamic Acid; Glutamine; Hepatic Encephal | 2013 |
Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response.
Topics: Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Animals, Newborn; Astrocytes; Brain Edema | 2005 |
Myoinositol administration improves survival and reduces myelinolysis after rapid correction of chronic hyponatremia in rats.
Topics: Animals; Arginine Vasopressin; Behavior, Animal; Blood Glucose; Brain; Demyelinating Diseases; Disea | 2006 |
Behavioral evidence for the existence of two pools of cellular inositol.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Hypernatremia; Hyponatremia; Inositol; | 1994 |
Organic osmolytes in acute hyponatremia.
Topics: Acute Disease; Amino Acids; Animals; Brain; Creatine; Deamino Arginine Vasopressin; Hyponatremia; In | 1993 |
Brain uptake of myoinositol after exogenous administration.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Brain; Hypernatremia; Hyponatremia; Infusi | 2002 |
Rapid (24-hour) reaccumulation of brain organic osmolytes (particularly myo-inositol) in azotemic rats after correction of chronic hyponatremia.
Topics: Animals; Body Water; Brain; Chronic Disease; Hyponatremia; Inositol; Male; Mercuric Chloride; Potass | 2002 |
The role of polyols in cerebral cell volume regulation in hypernatremic and hyponatremic states.
Topics: Aldehyde Reductase; Analysis of Variance; Animals; Brain; Electrolytes; Hypernatremia; Hyponatremia; | 1991 |
myo-inositol: a newly identified nonnitrogenous osmoregulatory molecule in mammalian brain.
Topics: Adaptation, Physiological; Animals; Brain; Hypernatremia; Hyponatremia; Inositol; Mice; Water-Electr | 1989 |