inositol has been researched along with Hyperglycemia, Postprandial in 78 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Hyperglycemia, Postprandial: Abnormally high BLOOD GLUCOSE level after a meal.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because it reflects the current status of hyperglycemia, urinary myo-inositol (UMI) may be useful." | 7.80 | The utility of urinary myo-inositol as a marker of glucose intolerance. ( Furusyo, N; Hayashi, J; Hayashi, T; Ihara, T; Ikezaki, H; Kainuma, M; Murata, M; Ogawa, E; Okada, K, 2014) |
| " The present experiment was designed to determine: 1) if hyperglycemia-induced membrane injury is associated with intracellular and/or extracellular lipid disturbances; 2) if supplemental myo-inositol therapy prevents hyperglycemia-induced embryopathy; 3) if a correlation exists between dietary myo-inositol, serum and tissue levels of myo-inositol, and conceptus development; and 4) the cellular content of arachidonic acid following myo-inositol supplementation." | 7.70 | Dietary myo-inositol therapy in hyperglycemia-induced embryopathy. ( Borenstein, M; Khandelwal, M; Reece, EA; Wu, YK, 1998) |
| "In many tissues, hyperglycemia alters the activities of the Na(+)-dependent myo-inositol (Na/MI) transporter, Na(+)-K(+)-ATPase, and protein kinase C (PKC)." | 7.69 | Hyperglycemia-induced changes in Na+/myo-inositol transport, Na(+)-K(+)-ATPase, and protein kinase C activity in proximal tubule cells. ( Cole, JA; Walker, RE; Yordy, MR, 1995) |
| " The current investigation was undertaken to assess the use of dietary myo-inositol supplementation as a pharmacologic prophylaxis to obviate the teratogenic effects of hyperglycemia in an in vivo study." | 7.69 | Dietary intake of myo-inositol and neural tube defects in offspring of diabetic rats. ( Borenstein, M; Khandelwal, M; Reece, EA; Wu, YK, 1997) |
| "myo-Inositol accumulation and incorporation into phosphoinositides was decreased in neuroblastoma cells chronically exposed to medium containing 30 mmol/L glucose or 30 mmol/L galactose." | 7.68 | Reversal of hyperglycemic-induced defects in myo-inositol metabolism and Na+/K+ pump activity in cultured neuroblastoma cells by normalizing glucose levels. ( Davidson, EP; Dunlap, JA; Stefani, MR; Yorek, MA, 1993) |
| "We have shown that myo-inositol in the cultured rat embryo is diminished whenever malformations are induced by hyperglycemia and that the malformations and reductions of tissue myo-inositol content are not corrected by aldose reductase inhibitors." | 7.68 | Uptake of myo-inositol by early-somite rat conceptus. Transport kinetics and effects of hyperglycemia. ( Freinkel, N; Garcia-Palmer, FJ; Weigensberg, MJ, 1990) |
| "We previously reported that a chronic supplementation with myo-inositol (MI) improved insulin sensitivity and reduced fat accretion in mice." | 3.81 | Abnormalities in myo-inositol metabolism associated with type 2 diabetes in mice fed a high-fat diet: benefits of a dietary myo-inositol supplementation. ( Croze, ML; Géloën, A; Soulage, CO, 2015) |
| "This study was designed to investigate the protective effects of d-Chiro-Inositol (DCI) enriched tartary buckwheat extract (DTBE) against high fructose (HF) diet-induced hyperglycemia and liver injury in mice." | 3.81 | Hypoglycemic and hepatoprotective effects of D-chiro-inositol-enriched tartary buckwheat extract in high fructose-fed mice. ( Guo, J; Hu, Y; Luo, Y; Ren, D; Yang, X; Zhao, Y, 2015) |
| " Because it reflects the current status of hyperglycemia, urinary myo-inositol (UMI) may be useful." | 3.80 | The utility of urinary myo-inositol as a marker of glucose intolerance. ( Furusyo, N; Hayashi, J; Hayashi, T; Ihara, T; Ikezaki, H; Kainuma, M; Murata, M; Ogawa, E; Okada, K, 2014) |
| "Peripheral hyperglycemia was associated with significant increases in brain sorbitol (7." | 3.74 | Hyperglycemia not hypoglycemia alters neuronal dendrites and impairs spatial memory. ( Chong, L; Diamond, DM; Hanna, S; Malone, JI; Mervis, RF; Park, CR; Saporta, S, 2008) |
| " The present experiment was designed to determine: 1) if hyperglycemia-induced membrane injury is associated with intracellular and/or extracellular lipid disturbances; 2) if supplemental myo-inositol therapy prevents hyperglycemia-induced embryopathy; 3) if a correlation exists between dietary myo-inositol, serum and tissue levels of myo-inositol, and conceptus development; and 4) the cellular content of arachidonic acid following myo-inositol supplementation." | 3.70 | Dietary myo-inositol therapy in hyperglycemia-induced embryopathy. ( Borenstein, M; Khandelwal, M; Reece, EA; Wu, YK, 1998) |
| "In many tissues, hyperglycemia alters the activities of the Na(+)-dependent myo-inositol (Na/MI) transporter, Na(+)-K(+)-ATPase, and protein kinase C (PKC)." | 3.69 | Hyperglycemia-induced changes in Na+/myo-inositol transport, Na(+)-K(+)-ATPase, and protein kinase C activity in proximal tubule cells. ( Cole, JA; Walker, RE; Yordy, MR, 1995) |
| " The current investigation was undertaken to assess the use of dietary myo-inositol supplementation as a pharmacologic prophylaxis to obviate the teratogenic effects of hyperglycemia in an in vivo study." | 3.69 | Dietary intake of myo-inositol and neural tube defects in offspring of diabetic rats. ( Borenstein, M; Khandelwal, M; Reece, EA; Wu, YK, 1997) |
| "myo-Inositol accumulation and incorporation into phosphoinositides was decreased in neuroblastoma cells chronically exposed to medium containing 30 mmol/L glucose or 30 mmol/L galactose." | 3.68 | Reversal of hyperglycemic-induced defects in myo-inositol metabolism and Na+/K+ pump activity in cultured neuroblastoma cells by normalizing glucose levels. ( Davidson, EP; Dunlap, JA; Stefani, MR; Yorek, MA, 1993) |
| "Since inositol (Ins) depletion appears to be an important mechanism of cell injury in diabetic glomerulopathy, we studied Ins transport in cultured rat mesangial cells during hyperglycemia." | 3.68 | Regulation of inositol transport by glucose and protein kinase C in mesangial cells. ( Crews, FT; Guzman, NJ, 1992) |
| "We have shown that myo-inositol in the cultured rat embryo is diminished whenever malformations are induced by hyperglycemia and that the malformations and reductions of tissue myo-inositol content are not corrected by aldose reductase inhibitors." | 3.68 | Uptake of myo-inositol by early-somite rat conceptus. Transport kinetics and effects of hyperglycemia. ( Freinkel, N; Garcia-Palmer, FJ; Weigensberg, MJ, 1990) |
| "Postprandial hyperglycemia and hyperlipidemia are considered risk factors for cardiovascular disease." | 2.72 | An alpha-glucosidase inhibitor, voglibose, reduces oxidative stress markers and soluble intercellular adhesion molecule 1 in obese type 2 diabetic patients. ( Aizawa-Abe, M; Kuzuya, H; Ogawa, Y; Satoh, N; Shimatsu, A; Suganami, T; Yamada, K, 2006) |
| "Postprandial hyperglycemia is frequently associated with visceral obesity which plays a key role in metabolic abnormalities such as dyslipidemia and hypertension." | 2.42 | [Pharmacological treatment of postprandial hyperglycemia in hypertensive patients with type 2 diabetes mellitus]. ( Yamada, K, 2003) |
| "The combination significantly reduced postprandial hyperglycemia after each meal." | 1.40 | The glycemic/metabolic responses to meal tolerance tests at breakfast, lunch and dinner, and effects of the mitiglinide/voglibose fixed-dose combination on postprandial profiles in Japanese patients with type 2 diabetes mellitus. ( Cho, KY; Nakamura, A; Nomoto, H; Ono, Y, 2014) |
| "Seventeen type 2 diabetes patients were given sitagliptin 50 mg/day or voglibose 0." | 1.39 | Comparison of glycemic variability in patients with type 2 diabetes given sitagliptin or voglibose: a continuous glucose monitoring-based pilot study. ( Ando, K; Morimoto, A; Nishimura, R; Sakamoto, M; Seo, C; Tsujino, D; Utsunomiya, K, 2013) |
| "The brain metabolites of 17 men with type 1 diabetes and 12 age-matched non-diabetic men (22-43 years old) were studied after an overnight fast (plasma glucose 9." | 1.35 | Hyperglycaemia is associated with changes in the regional concentrations of glucose and myo-inositol within the brain. ( Groop, PH; Heikkilä, O; Heikkinen, S; Lundbom, N; Mäkimattila, S; Timonen, M, 2009) |
| "A total of 21 inpatients with type 2 diabetes were recruited to a single-center, 2-period, crossover trial." | 1.33 | Effect of two alpha-glucosidase inhibitors, voglibose and acarbose, on postprandial hyperglycemia correlates with subjective abdominal symptoms. ( Fujisawa, T; Ikegami, H; Inoue, K; Kawabata, Y; Ogihara, T, 2005) |
| "However, the association between type 2 diabetes and oxidative stress in the pancreatic beta-cells has not been previously described." | 1.30 | Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes. ( Hiai, H; Ihara, Y; Ikeda, H; Odaka, H; Seino, Y; Tanaka, T; Toyokuni, S; Uchida, K; Yamada, Y, 1999) |
| "myo-Inositol uptake was restored to normal in a time-dependent manner during recovery of islets at 5." | 1.29 | Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATPase in glucose-desensitized rat islets. ( Laychock, SG; Xia, M, 1993) |
| "Both diabetic hyperglycemia and galactosemia caused the prolongation of peak latencies and in some cases a reduction in the amplitudes of oscillatory potentials on the b-wave." | 1.27 | The development of electroretinogram abnormalities and the possible role of polyol pathway activity in diabetic hyperglycemia and galactosemia. ( Fujimori, S; Hirata, Y; Okada, K; Segawa, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (17.95) | 18.7374 |
| 1990's | 23 (29.49) | 18.2507 |
| 2000's | 16 (20.51) | 29.6817 |
| 2010's | 21 (26.92) | 24.3611 |
| 2020's | 4 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| Mukherjee, S | 1 |
| Chakraborty, M | 1 |
| Haubner, J | 1 |
| Ernst, G | 1 |
| DePasquale, M | 1 |
| Carpenter, D | 1 |
| Barrow, JC | 1 |
| Chakraborty, A | 1 |
| Hedrington, MS | 1 |
| Davis, SN | 1 |
| Shah, P | 2 |
| Chavda, V | 2 |
| Patel, S | 1 |
| Bhadada, S | 2 |
| Ashraf, GM | 1 |
| Patel, SS | 1 |
| Baldassarre, MPA | 1 |
| Di Tomo, P | 1 |
| Centorame, G | 1 |
| Pandolfi, A | 1 |
| Di Pietro, N | 1 |
| Consoli, A | 1 |
| Formoso, G | 1 |
| Kaneko, K | 1 |
| Satake, C | 1 |
| Izumi, T | 1 |
| Tanaka, M | 1 |
| Yamamoto, J | 1 |
| Asai, Y | 1 |
| Sawada, S | 1 |
| Imai, J | 1 |
| Yamada, T | 1 |
| Katagiri, H | 1 |
| Ono, Y | 3 |
| Kameda, H | 1 |
| Cho, KY | 2 |
| Seo, C | 1 |
| Sakamoto, M | 1 |
| Nishimura, R | 1 |
| Tsujino, D | 1 |
| Ando, K | 1 |
| Morimoto, A | 1 |
| Utsunomiya, K | 1 |
| Hernández-Mijares, A | 2 |
| Bañuls, C | 2 |
| Peris, JE | 1 |
| Monzó, N | 2 |
| Jover, A | 1 |
| Bellod, L | 1 |
| Victor, VM | 2 |
| Rocha, M | 2 |
| Nakamura, A | 2 |
| Nomoto, H | 2 |
| Lee, BH | 1 |
| Lee, CC | 1 |
| Wu, SC | 1 |
| Ikezaki, H | 1 |
| Furusyo, N | 1 |
| Okada, K | 3 |
| Ihara, T | 1 |
| Hayashi, T | 1 |
| Ogawa, E | 1 |
| Kainuma, M | 1 |
| Murata, M | 1 |
| Hayashi, J | 1 |
| Kobayashi, K | 1 |
| Yokoh, H | 1 |
| Sato, Y | 2 |
| Takemoto, M | 1 |
| Uchida, D | 1 |
| Kanatsuka, A | 1 |
| Kuribayashi, N | 1 |
| Terano, T | 1 |
| Hashimoto, N | 1 |
| Sakurai, K | 1 |
| Hanaoka, H | 1 |
| Ishikawa, K | 1 |
| Onishi, S | 1 |
| Yokote, K | 1 |
| Osonoi, T | 1 |
| Saito, M | 1 |
| Tamasawa, A | 1 |
| Ishida, H | 1 |
| Osonoi, Y | 1 |
| Kamoshima, H | 1 |
| Croze, ML | 1 |
| Géloën, A | 1 |
| Soulage, CO | 1 |
| Rovira-Llopis, S | 1 |
| Falcón, R | 1 |
| Veses, S | 1 |
| Hu, Y | 1 |
| Zhao, Y | 1 |
| Ren, D | 1 |
| Guo, J | 1 |
| Luo, Y | 1 |
| Yang, X | 1 |
| Matsumoto, Y | 1 |
| Ishii, M | 1 |
| Sekimizu, K | 1 |
| Chukwuma, CI | 1 |
| Ibrahim, MA | 1 |
| Islam, MS | 1 |
| Hirasawa, Y | 1 |
| Matsui, Y | 1 |
| Ohtsu, S | 1 |
| Yamane, K | 1 |
| Toyoshi, T | 1 |
| Kyuki, K | 1 |
| Sakai, T | 1 |
| Feng, Y | 1 |
| Nagamatsu, T | 1 |
| Koh, N | 1 |
| Sakamoto, S | 1 |
| Chino, F | 1 |
| Malone, JI | 1 |
| Hanna, S | 1 |
| Saporta, S | 1 |
| Mervis, RF | 1 |
| Park, CR | 1 |
| Chong, L | 1 |
| Diamond, DM | 1 |
| Heikkilä, O | 1 |
| Lundbom, N | 1 |
| Timonen, M | 1 |
| Groop, PH | 1 |
| Heikkinen, S | 1 |
| Mäkimattila, S | 1 |
| Sivakumar, S | 2 |
| Subramanian, SP | 2 |
| Abe, M | 1 |
| Maruyama, T | 1 |
| Maruyama, N | 1 |
| Matsumoto, K | 1 |
| Palsamy, P | 1 |
| Shen, H | 1 |
| Shao, M | 1 |
| Cho, KW | 1 |
| Wang, S | 1 |
| Chen, Z | 1 |
| Sheng, L | 1 |
| Wang, T | 1 |
| Liu, Y | 1 |
| Rui, L | 1 |
| Standl, E | 1 |
| Schnell, O | 1 |
| Inoue, M | 1 |
| Odaka, H | 2 |
| Watanabe, K | 1 |
| Kawamori, R | 1 |
| Eriksson, UJ | 1 |
| Cederberg, J | 1 |
| Wentzel, P | 1 |
| Yamada, K | 2 |
| Fujisawa, T | 1 |
| Ikegami, H | 1 |
| Inoue, K | 1 |
| Kawabata, Y | 1 |
| Ogihara, T | 1 |
| Nakamura, J | 1 |
| Yamazaki, H | 1 |
| Philbrick, W | 1 |
| Zawalich, KC | 2 |
| Zawalich, WS | 2 |
| Liao, Y | 1 |
| Takashima, S | 1 |
| Zhao, H | 1 |
| Asano, Y | 1 |
| Shintani, Y | 1 |
| Minamino, T | 1 |
| Kim, J | 1 |
| Fujita, M | 1 |
| Hori, M | 1 |
| Kitakaze, M | 1 |
| Satoh, N | 1 |
| Shimatsu, A | 1 |
| Aizawa-Abe, M | 1 |
| Suganami, T | 1 |
| Kuzuya, H | 1 |
| Ogawa, Y | 1 |
| Yamazaki, K | 1 |
| Inoue, T | 1 |
| Yasuda, N | 1 |
| Nagakura, T | 1 |
| Takenaka, O | 1 |
| Clark, R | 1 |
| Saeki, T | 1 |
| Tanaka, I | 1 |
| Tomlinson, DR | 1 |
| Mayer, JH | 1 |
| Greene, DA | 5 |
| Cole, JA | 1 |
| Walker, RE | 1 |
| Yordy, MR | 1 |
| Sima, AA | 1 |
| Stevens, MJ | 2 |
| Feldman, EL | 1 |
| Killen, PD | 2 |
| Henry, DN | 2 |
| Thomas, T | 1 |
| Dananberg, J | 1 |
| Lattimer, SA | 1 |
| Thomas, TP | 1 |
| Xia, M | 1 |
| Laychock, SG | 1 |
| Yorek, MA | 1 |
| Dunlap, JA | 1 |
| Stefani, MR | 1 |
| Davidson, EP | 1 |
| Gruetter, R | 1 |
| Garwood, M | 1 |
| Uğurbil, K | 1 |
| Seaquist, ER | 1 |
| Reece, EA | 2 |
| Khandelwal, M | 2 |
| Wu, YK | 2 |
| Borenstein, M | 2 |
| Iwamoto, Y | 1 |
| Mooradian, AD | 1 |
| Thurman, JE | 1 |
| Ihara, Y | 1 |
| Toyokuni, S | 1 |
| Uchida, K | 1 |
| Tanaka, T | 1 |
| Ikeda, H | 1 |
| Hiai, H | 1 |
| Seino, Y | 1 |
| Yamada, Y | 1 |
| Fonteles, MC | 1 |
| Almeida, MQ | 1 |
| Larner, J | 1 |
| Anderson, JW | 1 |
| Winegrad, AI | 3 |
| Simmons, DA | 1 |
| Edwardson, JM | 1 |
| Dean, PM | 1 |
| McCaleb, ML | 1 |
| Sredy, J | 1 |
| Guzman, NJ | 1 |
| Crews, FT | 1 |
| Hod, M | 2 |
| Star, S | 2 |
| Passonneau, JV | 1 |
| Unterman, TG | 2 |
| Freinkel, N | 3 |
| Hotta, N | 1 |
| Sakamoto, N | 1 |
| Hashimoto, M | 1 |
| Akazawa, S | 1 |
| Akazawa, M | 1 |
| Akashi, M | 1 |
| Yamamoto, H | 1 |
| Maeda, Y | 1 |
| Yamaguchi, Y | 1 |
| Yamasaki, H | 1 |
| Tahara, D | 1 |
| Nakanishi, T | 1 |
| Shulman, GI | 1 |
| Rossetti, L | 1 |
| Moller, DE | 1 |
| Moses, AC | 1 |
| Passonneau, J | 1 |
| Weigensberg, MJ | 1 |
| Garcia-Palmer, FJ | 1 |
| Sinclair, SH | 1 |
| Nesler, CL | 1 |
| Schwartz, SS | 1 |
| Legan, E | 1 |
| Balabolkin, MI | 1 |
| Islambekov, RR | 1 |
| Mascardo, RN | 1 |
| Segawa, M | 1 |
| Hirata, Y | 1 |
| Fujimori, S | 1 |
| Varma, SD | 1 |
| Kinoshita, JH | 1 |
| Lewin, LM | 1 |
| Szeinberg, A | 1 |
| Lepkifker, E | 1 |
| Prockop, LD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Quercetin in Type 2 Diabetes: Impact on Glucose Tolerance and Postprandial Endothelial Function.[NCT01839344] | Phase 2 | 19 participants (Actual) | Interventional | 2013-05-31 | Completed | ||
| Inhibition of Intestinal Glucose Absorption by the Bioflavonoid Quercetin in the Obese and in Obese Type 2 Diabetics[NCT00065676] | Phase 2 | 24 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for inositol and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
Considerations when using alpha-glucosidase inhibitors in the treatment of type 2 diabetes.
Topics: 1-Deoxynojirimycin; Acarbose; Aged; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type | 2019 |
Alpha-glucosidase inhibitors 2012 - cardiovascular considerations and trial evaluation.
Topics: 1-Deoxynojirimycin; Acarbose; Cardiovascular Diseases; Diabetes Complications; Glycoside Hydrolase I | 2012 |
[alpha-Glucosidase inhibitor, its structure and mechanism of antidiabetic action].
Topics: Acarbose; Animals; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Hum | 2002 |
[Combination therapy with insulin and alpha-glucosidase inhibitor].
Topics: Acarbose; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Thera | 2002 |
Congenital malformations in offspring of diabetic mothers--animal and human studies.
Topics: Animals; Arachidonic Acid; Congenital Abnormalities; Diabetes Complications; Female; Gene Expression | 2003 |
[Pharmacological treatment of postprandial hyperglycemia in hypertensive patients with type 2 diabetes mellitus].
Topics: Acarbose; Cyclohexanes; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Enzyme | 2003 |
[Effects of voglibose, alpha-glucosidase inhibitor in treatment of impaired glucose tolerance].
Topics: Animals; Carbohydrate Metabolism; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucose Intolerance; | 2005 |
Defects of axonal transport in diabetes mellitus--a possible contribution to the aetiology of diabetic neuropathy.
Topics: Animals; Axonal Transport; Body Temperature; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dia | 1984 |
Aldose reductase inhibitors: an approach to the treatment of diabetic nerve damage.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Neuropathi | 1993 |
[Management of postprandial hyperglycemia].
Topics: Acarbose; Diabetes Mellitus, Type 2; Diet, Diabetic; Exercise Therapy; Humans; Hyperglycemia; Hypogl | 1997 |
Drug therapy of postprandial hyperglycaemia.
Topics: 1-Deoxynojirimycin; Acarbose; Amyloid; Carbamates; Diabetes Mellitus; Enzyme Inhibitors; Glucosamine | 1999 |
Metabolic abnormalities contributing to diabetic complications. II. Peripheral nerves.
Topics: Animals; Axons; Cricetinae; Diabetes Mellitus; Diabetic Neuropathies; Disease Models, Animal; Glucos | 1976 |
Acute and chronic complications of diabetes mellitus in older patients.
Topics: Adult; Aged; Aging; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Diabetic Coma; Diabet | 1986 |
10 trials available for inositol and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
Mitiglinide/voglibose fixed-dose combination improves postprandial glycemic excursions in Japanese patients with type 2 diabetes mellitus.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Combinations; Female; H | 2013 |
A single acute dose of pinitol from a naturally-occurring food ingredient decreases hyperglycaemia and circulating insulin levels in healthy subjects.
Topics: Adult; Beverages; Blood Glucose; Down-Regulation; Female; Humans; Hyperglycemia; Inositol; Insulin; | 2013 |
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin compared with α-glucosidase inhibitor in Japanese patients with type 2 diabetes inadequately controlled on sulfonylurea alone (SUCCESS-2): a multicenter, randomized, open-label, non-i
Topics: 1-Deoxynojirimycin; Aged; alpha-Glucosidases; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inh | 2014 |
Effects of sitagliptin or mitiglinide as an add-on to acarbose on daily blood glucose fluctuations measured by 72 h subcutaneous continuous glucose monitoring in Japanese patients with type 2 diabetes: a prospective randomized study.
Topics: Acarbose; Aged; Asian People; Blood Glucose; Diabetes Mellitus, Type 2; Drug Substitution; Drug Ther | 2014 |
Glycemic/metabolic responses to identical meal tolerance tests at breakfast, lunch and dinner in Japanese patients with type 2 diabetes mellitus treated with a dipeptidyl peptidase-4 inhibitor and the effects of adding a mitiglinide/voglibose fixed-dose c
Topics: Aged; Blood Glucose; Breakfast; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug | 2014 |
Chronic consumption of an inositol-enriched carob extract improves postprandial glycaemia and insulin sensitivity in healthy subjects: A randomized controlled trial.
Topics: Adult; Blood Glucose; Dietary Supplements; Double-Blind Method; Fabaceae; Female; Fruit; Humans; Hyp | 2016 |
Improvement in medication compliance and glycemic control with voglibose oral disintegrating tablet.
Topics: Administration, Oral; Aged; Female; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; | 2008 |
Combination therapy with mitiglinide and voglibose improves glycemic control in type 2 diabetic patients on hemodialysis.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; H | 2010 |
Tighter control of postprandial hyperglycemia with mitiglinide/voglibose fixed-dose combination in Japanese patients with type 2 diabetes mellitus.
Topics: Aged; Asian People; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Combinations; | 2012 |
An alpha-glucosidase inhibitor, voglibose, reduces oxidative stress markers and soluble intercellular adhesion molecule 1 in obese type 2 diabetic patients.
Topics: Adult; Biomarkers; Diabetes Mellitus, Type 2; Female; Glycoside Hydrolase Inhibitors; Humans; Hyperg | 2006 |
55 other studies available for inositol and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
The IP6K Inhibitor LI-2242 Ameliorates Diet-Induced Obesity, Hyperglycemia, and Hepatic Steatosis in Mice by Improving Cell Metabolism and Insulin Signaling.
Topics: Animals; Diet; Diphosphates; Hyperglycemia; Inositol; Insulin; Insulin Resistance; Lipid Metabolism; | 2023 |
Promising Anti-stroke Signature of Voglibose: Investigation through In- Silico Molecular Docking and Virtual Screening in In-Vivo Animal Studies.
Topics: Animals; Cerebrovascular Disorders; Computer Simulation; Diabetes Mellitus, Experimental; Diabetes M | 2020 |
Pre-exposure of voglibose exerts cerebroprotective effects through attenuating activation of the polyol pathway and inflammation.
Topics: Animals; Hyperglycemia; Inflammation; Inositol; Male; Polymers; Rats | 2021 |
Myoinositol Reduces Inflammation and Oxidative Stress in Human Endothelial Cells Exposed In Vivo to Chronic Hyperglycemia.
Topics: Adult; Antioxidants; Cell Adhesion; Cell Adhesion Molecules; Diabetes, Gestational; Female; Human Um | 2021 |
Enhancement of postprandial endogenous insulin secretion rather than exogenous insulin injection ameliorated insulin antibody-induced unstable diabetes: a case report.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Gl | 2019 |
Comparison of glycemic variability in patients with type 2 diabetes given sitagliptin or voglibose: a continuous glucose monitoring-based pilot study.
Topics: Aged; Asian People; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Drug Combinations; Fe | 2013 |
The glycemic/metabolic responses to meal tolerance tests at breakfast, lunch and dinner, and effects of the mitiglinide/voglibose fixed-dose combination on postprandial profiles in Japanese patients with type 2 diabetes mellitus.
Topics: Aged; Blood Glucose; Breakfast; C-Reactive Protein; Diabetes Mellitus, Type 2; Drug Combinations; Fa | 2014 |
Ice plant (Mesembryanthemum crystallinum) improves hyperglycaemia and memory impairments in a Wistar rat model of streptozotocin-induced diabetes.
Topics: Acetylcholinesterase; Animals; Avoidance Learning; Blood Glucose; Brain; Cholinesterase Inhibitors; | 2014 |
The utility of urinary myo-inositol as a marker of glucose intolerance.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Cross-Sectional Studies; Female; Glucose Intolerance; Glucos | 2014 |
Abnormalities in myo-inositol metabolism associated with type 2 diabetes in mice fed a high-fat diet: benefits of a dietary myo-inositol supplementation.
Topics: Adipokines; Adipose Tissue, White; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Dietary Suppl | 2015 |
Hypoglycemic and hepatoprotective effects of D-chiro-inositol-enriched tartary buckwheat extract in high fructose-fed mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; C-Reactive Protein; Chemi | 2015 |
An in vivo invertebrate evaluation system for identifying substances that suppress sucrose-induced postprandial hyperglycemia.
Topics: Acarbose; Animals; Bombyx; Dietary Sucrose; Disease Models, Animal; Glucose; Glycoside Hydrolase Inh | 2016 |
Myo-inositol inhibits intestinal glucose absorption and promotes muscle glucose uptake: a dual approach study.
Topics: Administration, Oral; Animals; Biological Transport; Blood Glucose; Carbohydrate Metabolism; Diabete | 2016 |
Involvement of hyperglycemia in deposition of aggregated protein in glomeruli of diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Glucose; Glycated Hemoglobin; Glycated Serum Albumin; Gly | 2008 |
Hyperglycemia not hypoglycemia alters neuronal dendrites and impairs spatial memory.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Dendrites; Dendritic Spines; Diabetes Mellitus, Experimen | 2008 |
Hyperglycaemia is associated with changes in the regional concentrations of glucose and myo-inositol within the brain.
Topics: Adult; Blood Glucose; Blood Pressure; Body Mass Index; Brain; C-Reactive Protein; Cholesterol, HDL; | 2009 |
Pancreatic tissue protective nature of D-Pinitol studied in streptozotocin-mediated oxidative stress in experimental diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Hyperglycemia; Inositol; Insulin-Secreting C | 2009 |
Impact of D-pinitol on the attenuation of proinflammatory cytokines, hyperglycemia-mediated oxidative stress and protection of kidney tissue ultrastructure in streptozotocin-induced diabetic rats.
Topics: Animals; Cytokines; Diabetes Mellitus, Experimental; Hyperglycemia; Inositol; Kidney; Microscopy, El | 2010 |
Herbal constituent sequoyitol improves hyperglycemia and glucose intolerance by targeting hepatocytes, adipocytes, and β-cells.
Topics: Adipocytes, White; Animals; Cell Line; Cells, Cultured; Diabetes Mellitus, Experimental; Female; Glu | 2012 |
Effect of two alpha-glucosidase inhibitors, voglibose and acarbose, on postprandial hyperglycemia correlates with subjective abdominal symptoms.
Topics: Acarbose; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Fem | 2005 |
Acute and chronic effects of glucose and carbachol on insulin secretion and phospholipase C activation: studies with diazoxide and atropine.
Topics: Animals; Atropine; Carbachol; Colforsin; Diazoxide; Enzyme Activation; Glucose; Hyperglycemia; In Vi | 2006 |
Control of plasma glucose with alpha-glucosidase inhibitor attenuates oxidative stress and slows the progression of heart failure in mice.
Topics: Acetophenones; Animals; Blotting, Western; Body Weight; Cells, Cultured; Disease Progression; Echoca | 2006 |
Comparison of efficacies of a dipeptidyl peptidase IV inhibitor and alpha-glucosidase inhibitors in oral carbohydrate and meal tolerance tests and the effects of their combination in mice.
Topics: Acarbose; Administration, Oral; Animals; Area Under Curve; Blood Glucose; Carbohydrate Metabolism; D | 2007 |
Metabolic abnormalities in diabetic peripheral nerve: relation to impaired function.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Energy Metabolism; Female; Gluc | 1983 |
Hyperglycemia-induced changes in Na+/myo-inositol transport, Na(+)-K(+)-ATPase, and protein kinase C activity in proximal tubule cells.
Topics: Biological Transport; Cell Membrane; Cells, Cultured; Cytosol; Humans; Hyperglycemia; In Vitro Techn | 1995 |
Aldose reductase gene expression and osmotic dysregulation in cultured human retinal pigment epithelial cells.
Topics: Aldehyde Reductase; Blood Glucose; Cell Line; Fructose; Gene Expression; Glucose; Humans; Hyperglyce | 1993 |
Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATPase in glucose-desensitized rat islets.
Topics: Animals; Arginine; Biological Transport; Carbachol; Cells, Cultured; Disease Models, Animal; Dose-Re | 1993 |
Reversal of hyperglycemic-induced defects in myo-inositol metabolism and Na+/K+ pump activity in cultured neuroblastoma cells by normalizing glucose levels.
Topics: Animals; Biological Transport; Blood Glucose; Galactose; Glucose; Hyperglycemia; Inositol; Neuroblas | 1993 |
Observation of resolved glucose signals in 1H NMR spectra of the human brain at 4 Tesla.
Topics: Blood Glucose; Body Water; Brain; Carbon Isotopes; Creatine; Glucose; Humans; Hydrogen; Hyperglycemi | 1996 |
Dietary intake of myo-inositol and neural tube defects in offspring of diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Embryonic and Fetal Development; Female; Hyperglycemia; In | 1997 |
Dietary myo-inositol therapy in hyperglycemia-induced embryopathy.
Topics: Animals; Arachidonic Acid; Blood Glucose; Diabetes Mellitus, Experimental; Embryo, Mammalian; Embryo | 1998 |
Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Blood Glucose; Deoxyguanosine; Diabetes Mellitus, T | 1999 |
Antihyperglycemic effects of 3-O-methyl-D-chiro-inositol and D-chiro-inositol associated with manganese in streptozotocin diabetic rats.
Topics: Animals; Blood Glucose; Chlorides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Femal | 2000 |
Diabetic polyneuropathy: the importance of insulin deficiency, hyperglycemia and alterations in myoinositol metabolism in its pathogenesis.
Topics: Acute Disease; Animals; Demyelinating Diseases; Diabetes Mellitus, Experimental; Diabetic Neuropathi | 1976 |
Mechanisms in rabbit aorta for hyperglycaemia-induced alterations in angiotensin II and norepinephrine effects.
Topics: Angiotensin II; Animals; Aorta; Glucose; Hyperglycemia; Inositol; Kinetics; Male; Muscle, Smooth, Va | 1992 |
Inhibition of alloxan-induced hyperglycaemia by compounds of similar molecular structure.
Topics: Allantoin; Alloxan; Animals; Barbiturates; Blood Glucose; Caffeine; Ethosuximide; Hyperglycemia; Ino | 1992 |
Metabolic abnormalities of the hyperglycemic obese Zucker rat.
Topics: Animals; Fructose; Glucose; Glycosuria; Hyperglycemia; Inositol; Male; Obesity; Rats; Rats, Zucker; | 1992 |
Regulation of inositol transport by glucose and protein kinase C in mesangial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Biological Transport, Active; Cel | 1992 |
Understanding diabetic neuropathy.
Topics: Diabetic Neuropathies; Humans; Hyperglycemia; Inositol; Nerve Growth Factors; Peripheral Nerves; Tim | 1991 |
Effect of hyperglycemia on sorbitol and myo-inositol content of cultured rat conceptus: prevention of dysmorphogenesis with aldose reductase inhibitors and myo-inositol.
Topics: Aldehyde Reductase; Animals; Blood; Congenital Abnormalities; Culture Media; Culture Techniques; Fem | 1991 |
[Abnormal metabolism of polyol pathway and diabetic complications].
Topics: Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Inositol; NADP; Osmotic Pressure; Polymers | 1991 |
Effects of hyperglycaemia on sorbitol and myo-inositol contents of cultured embryos: treatment with aldose reductase inhibitor and myo-inositol supplementation.
Topics: Aldehyde Reductase; Animals; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fetal Disea | 1990 |
Chronic in vivo hyperglycemia impairs phosphoinositide hydrolysis and insulin release in isolated perifused rat islets.
Topics: Animals; Blood Glucose; Chronic Disease; Glucose; Hydrolysis; Hyperglycemia; In Vitro Techniques; In | 1990 |
Advances in the diagnosis and pathogenesis of diabetes mellitus and its complications.
Topics: Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dia | 1990 |
Glucose-induced dysmorphogenesis in the cultured rat conceptus: prevention by supplementation with myo-inositol.
Topics: Animals; Congenital Abnormalities; Culture Media; Culture Techniques; Disease Models, Animal; Embryo | 1990 |
Uptake of myo-inositol by early-somite rat conceptus. Transport kinetics and effects of hyperglycemia.
Topics: Animals; Biological Transport; Congenital Abnormalities; Culture Techniques; DNA; Embryo, Mammalian; | 1990 |
Retinopathy in the pregnant diabetic.
Topics: Adult; Blood Flow Velocity; Diabetic Angiopathies; Diabetic Retinopathy; Enzymes; Female; Fluorescei | 1985 |
Effects of streptozotocin-induced hyperglycemia on agonist-stimulated phosphatidylinositol turnover in rat aorta.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hyperglycemia | 1989 |
[Diabetic polyneuropathy].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Humans; Hyperglycemia; Inositol; P | 1989 |
Banting lecture 1986. Does a common mechanism induce the diverse complications of diabetes?
Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Ne | 1987 |
The effects of hyperglycemia on the directed migration of wounded endothelial cell monolayers.
Topics: Animals; Cattle; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vasc | 1988 |
The development of electroretinogram abnormalities and the possible role of polyol pathway activity in diabetic hyperglycemia and galactosemia.
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Electroretinography; Galactitol; Galactosemias; | 1988 |
The absence of cataracts in mice with congenital hyperglycemia.
Topics: Alcohol Oxidoreductases; Animals; Cataract; Diabetes Mellitus; Diet; Fructose; Galactitol; Galactose | 1974 |
Gas chromatography measurement of myo-inositol in human blood, cerebrospinal fluid and seminal fluid.
Topics: Adult; Aged; Child, Preschool; Chromatography, Gas; Chromatography, Ion Exchange; Creatine Kinase; D | 1973 |
Hyperglycemia, polyol accumulation, and increased intracranial pressure.
Topics: Animals; Brain; Brain Edema; Cerebrospinal Fluid Proteins; Diabetic Ketoacidosis; Disease Models, An | 1971 |