Page last updated: 2024-10-19

inositol and Hyperandrogenism

inositol has been researched along with Hyperandrogenism in 9 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Hyperandrogenism: A condition caused by the excessive secretion of ANDROGENS from the ADRENAL CORTEX; the OVARIES; or the TESTES. The clinical significance in males is negligible. In women, the common manifestations are HIRSUTISM and VIRILISM as seen in patients with POLYCYSTIC OVARY SYNDROME and ADRENOCORTICAL HYPERFUNCTION.

Research Excerpts

ExcerptRelevanceReference
"The results of this study demonstrated a good efficacy of both treatments, although in the group treated with the combination of myo-inositol/monacolin K improvement in lipids and hyperandrogenism were significantly better."7.79[Evaluation of the myo-inositol-monacolin K association on hyperandrogenism and on the lipidic metabolism parameters in PCOS women]. ( Cappelli, V; De Leo, V; Di Sabatino, A; Morgante, G; Musacchio, MC, 2013)
"This new myo-inositol, monacolin K and lipoic acid association contains appropriate substances to contrast various etiopathogenic elements responsible for the onset of PCOS and the symptoms of hyperandrogenism and dyslipidemia related to it."5.20Polycystic ovary syndrome (PCOS) and hyperandrogenism: the role of a new natural association. ( Cappelli, V; De Leo, V; Di Sabatino, A; Massaro, MG; Morgante, G, 2015)
"Myo-inositol and D-chiro-inositol are capable of improving the ovarian function and metabolism of polycystic ovary syndrome (PCOS) patients."5.19Comparison between effects of myo-inositol and D-chiro-inositol on ovarian function and metabolic factors in women with PCOS. ( Barbaro, L; Laganà, AS; Pizzo, A, 2014)
"The results of this study demonstrated a good efficacy of both treatments, although in the group treated with the combination of myo-inositol/monacolin K improvement in lipids and hyperandrogenism were significantly better."3.79[Evaluation of the myo-inositol-monacolin K association on hyperandrogenism and on the lipidic metabolism parameters in PCOS women]. ( Cappelli, V; De Leo, V; Di Sabatino, A; Morgante, G; Musacchio, MC, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Menichini, D1
Ughetti, C1
Monari, F1
Di Vinci, PL1
Neri, I1
Facchinetti, F1
Fedeli, V1
Catizone, A1
Querqui, A1
Unfer, V2
Bizzarri, M1
Iervolino, M1
Lepore, E1
Forte, G1
Laganà, AS2
Buzzaccarini, G1
Morgante, G3
Massaro, MG2
Di Sabatino, A3
Cappelli, V3
De Leo, V3
Stracquadanio, M1
Ciotta, L1
Palumbo, MA1
Musacchio, MC1
Pizzo, A1
Barbaro, L1
Genazzani, AD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Inositols on Insulin Resistance in Children With Obesity (ONIRICO Trial)[NCT05701813]56 participants (Anticipated)Interventional2023-02-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for inositol and Hyperandrogenism

ArticleYear
Nutraceuticals and polycystic ovary syndrome: a systematic review of the literature.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2022, Volume: 38, Issue:8

    Topics: Dietary Supplements; Female; Glucose; Humans; Hyperandrogenism; Inositol; Polycystic Ovary Syndrome;

2022
The Role of Inositols in the Hyperandrogenic Phenotypes of PCOS: A Re-Reading of Larner's Results.
    International journal of molecular sciences, 2023, Mar-27, Volume: 24, Issue:7

    Topics: Androgens; Aromatase; Estrogens; Female; Follicle Stimulating Hormone; Humans; Hyperandrogenism; Ino

2023
Natural Molecules in the Management of Polycystic Ovary Syndrome (PCOS): An Analytical Review.
    Nutrients, 2021, May-15, Volume: 13, Issue:5

    Topics: Ascorbic Acid; Dietary Supplements; Dyslipidemias; Fatty Acids, Omega-3; Female; Flavanones; Flavono

2021
Therapeutic approach for metabolic disorders and infertility in women with PCOS.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2018, Volume: 34, Issue:1

    Topics: Androgen Antagonists; Anovulation; Clomiphene; Contraceptives, Oral, Hormonal; Female; Gonadotropins

2018
Inositol as putative integrative treatment for PCOS.
    Reproductive biomedicine online, 2016, Volume: 33, Issue:6

    Topics: Female; Humans; Hyperandrogenism; Hyperinsulinism; Inositol; Inositol Phosphates; Insulin; Insulin R

2016

Trials

2 trials available for inositol and Hyperandrogenism

ArticleYear
Comparison between effects of myo-inositol and D-chiro-inositol on ovarian function and metabolic factors in women with PCOS.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2014, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Amenorrhea; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follicl

2014
Polycystic ovary syndrome (PCOS) and hyperandrogenism: the role of a new natural association.
    Minerva ginecologica, 2015, Volume: 67, Issue:5

    Topics: Adult; Antioxidants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyslipidemias; Fem

2015

Other Studies

2 other studies available for inositol and Hyperandrogenism

ArticleYear
Effects of myo-inositol, gymnemic acid, and L-methylfolate in polycystic ovary syndrome patients.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2018, Volume: 34, Issue:6

    Topics: Adult; Blood Glucose; Body Mass Index; Body Weight; Drug Therapy, Combination; Female; Humans; Hyper

2018
[Evaluation of the myo-inositol-monacolin K association on hyperandrogenism and on the lipidic metabolism parameters in PCOS women].
    Minerva ginecologica, 2013, Volume: 65, Issue:1

    Topics: Adult; Drug Therapy, Combination; Female; Humans; Hyperandrogenism; Inositol; Lipid Metabolism; Lova

2013