inositol has been researched along with Huntington Disease in 4 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sturrock, A | 1 |
Laule, C | 1 |
Wyper, K | 1 |
Milner, RA | 1 |
Decolongon, J | 1 |
Dar Santos, R | 1 |
Coleman, AJ | 1 |
Carter, K | 1 |
Creighton, S | 1 |
Bechtel, N | 1 |
Bohlen, S | 1 |
Reilmann, R | 1 |
Johnson, HJ | 1 |
Hayden, MR | 1 |
Tabrizi, SJ | 1 |
Mackay, AL | 1 |
Leavitt, BR | 1 |
Graham, SF | 1 |
Kumar, PK | 1 |
Bjorndahl, T | 1 |
Han, B | 1 |
Yilmaz, A | 1 |
Sherman, E | 1 |
Bahado-Singh, RO | 1 |
Wishart, D | 1 |
Mann, D | 1 |
Green, BD | 1 |
Sarkar, S | 2 |
Rubinsztein, DC | 2 |
Krishna, G | 1 |
Imarisio, S | 1 |
Saiki, S | 1 |
O'Kane, CJ | 1 |
1 review available for inositol and Huntington Disease
Article | Year |
---|---|
Huntington's disease: degradation of mutant huntingtin by autophagy.
Topics: Autophagy; Humans; Huntingtin Protein; Huntington Disease; Inositol; Lithium Compounds; Mutation; Ne | 2008 |
3 other studies available for inositol and Huntington Disease
Article | Year |
---|---|
A longitudinal study of magnetic resonance spectroscopy Huntington's disease biomarkers.
Topics: Adult; Analysis of Variance; Aspartic Acid; Biomarkers; Brain; Cross-Sectional Studies; Female; Huma | 2015 |
Metabolic signatures of Huntington's disease (HD): (1)H NMR analysis of the polar metabolome in post-mortem human brain.
Topics: Brain; Case-Control Studies; Corpus Striatum; Frontal Lobe; Humans; Huntington Disease; Inositol; Le | 2016 |
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.
Topics: Animals; Autophagy; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Drosophila; Drosophila | 2008 |