inositol has been researched along with Heart Failure in 12 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Reduced myocardial levels of myo-inositol in the myocardium of MI animals point to altered phospholipid metabolism and membrane receptor function in heart failure." | 3.91 | Metabolomic analysis of serum and myocardium in compensated heart failure after myocardial infarction. ( Barupal, DK; Fan, S; Hammond, HK; Ichikawa, Y; McKirnan, MD; Patel, HH; Roth, DM; Zemljic-Harpf, AE; Zhang, Z, 2019) |
| "Since 1) dilated cardiomyopathy (DCM) causes chronic heart failure (CHF), and 2) augmentation of neurohumoral factors such as angiotensin II impairs glucose metabolism, we examined the rate of abnormal glucose metabolism in patients having both DCM and CHF and whether correction of the impairment of glucose metabolism would improve the pathophysiology of CHF in DCM patients." | 1.33 | Abnormal glucose tolerance contributes to the progression of chronic heart failure in patients with dilated cardiomyopathy. ( Asakura, M; Asanuma, H; Hashimura, K; Kanzaki, H; Kim, J; Kitakaze, M; Kokubo, Y; Komamura, K; Nakatani, S; Tomoike, H, 2006) |
| "The creatine level was independently correlated with half-recovery time and duration of heart failure symptoms in PWM (r = -0." | 1.30 | Cerebral metabolic abnormalities in congestive heart failure detected by proton magnetic resonance spectroscopy. ( Hong, MK; Kim, JJ; Kim, ST; Lee, CW; Lee, JH; Lim, TH; Park, SJ; Park, SW, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ejiri, K | 2 |
| Miyoshi, T | 2 |
| Kihara, H | 2 |
| Hata, Y | 2 |
| Nagano, T | 2 |
| Takaishi, A | 2 |
| Toda, H | 2 |
| Namba, S | 1 |
| Nakamura, Y | 2 |
| Akagi, S | 2 |
| Sakuragi, S | 2 |
| Minagawa, T | 2 |
| Kawai, Y | 2 |
| Nishii, N | 2 |
| Fuke, S | 2 |
| Yoshikawa, M | 2 |
| Nakamura, K | 2 |
| Ito, H | 2 |
| Nanba, S | 1 |
| McKirnan, MD | 1 |
| Ichikawa, Y | 1 |
| Zhang, Z | 1 |
| Zemljic-Harpf, AE | 1 |
| Fan, S | 1 |
| Barupal, DK | 1 |
| Patel, HH | 1 |
| Hammond, HK | 1 |
| Roth, DM | 1 |
| Woo, MA | 1 |
| Yadav, SK | 1 |
| Macey, PM | 1 |
| Fonarow, GC | 1 |
| Harper, RM | 1 |
| Kumar, R | 1 |
| Diercks, DB | 1 |
| Owen, K | 1 |
| Tolstikov, V | 1 |
| Sutter, M | 1 |
| Lee, CW | 3 |
| Lee, JH | 3 |
| Yang, HS | 2 |
| Lim, KH | 1 |
| Ahn, JM | 1 |
| Hong, MK | 3 |
| Park, SW | 3 |
| Park, SJ | 3 |
| Song, MG | 1 |
| Kim, JJ | 3 |
| Liao, Y | 1 |
| Takashima, S | 1 |
| Zhao, H | 1 |
| Asano, Y | 1 |
| Shintani, Y | 1 |
| Minamino, T | 1 |
| Kim, J | 2 |
| Fujita, M | 1 |
| Hori, M | 1 |
| Kitakaze, M | 2 |
| Nakatani, S | 1 |
| Hashimura, K | 1 |
| Komamura, K | 1 |
| Kanzaki, H | 1 |
| Asakura, M | 1 |
| Asanuma, H | 1 |
| Kokubo, Y | 1 |
| Tomoike, H | 1 |
| Kim, ST | 1 |
| Lim, TH | 2 |
| Nagai, Y | 1 |
| Hayakawa, T | 1 |
| Abe, T | 1 |
| Nomura, G | 1 |
| Malloy, CR | 1 |
| Song, JK | 1 |
3 trials available for inositol and Heart Failure
| Article | Year |
|---|---|
Effects of luseogliflozin and voglibose on high-risk lipid profiles and inflammatory markers in diabetes patients with heart failure.
Topics: Adiponectin; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Diabetes Mellitus, Type 2; Glucose; H | 2022 |
Effect of Luseogliflozin on Heart Failure With Preserved Ejection Fraction in Patients With Diabetes Mellitus.
Topics: Aged; Biomarkers; Diabetes Mellitus, Type 2; Drug Administration Schedule; Female; Heart Failure; Hu | 2020 |
Prognostic significance of cerebral metabolic abnormalities in patients with congestive heart failure.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Creatine; Female; Follow-Up Studies | 2001 |
9 other studies available for inositol and Heart Failure
| Article | Year |
|---|---|
Metabolomic analysis of serum and myocardium in compensated heart failure after myocardial infarction.
Topics: Animals; Echocardiography; Female; Heart Failure; Heart Ventricles; Inosine; Inositol; Male; Metabol | 2019 |
Brain metabolites in autonomic regulatory insular sites in heart failure.
Topics: Adult; Autonomic Nervous System; Cerebral Cortex; Choline; Creatine; Female; Heart Failure; Humans; | 2014 |
Urinary metabolomic analysis for the identification of renal injury in patients with acute heart failure.
Topics: Aged; Biomarkers; Creatinine; Discriminant Analysis; Female; Gas Chromatography-Mass Spectrometry; G | 2012 |
Effects of heart transplantation on cerebral metabolic abnormalities in patients with congestive heart failure.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Heart Failure; Heart Transplantation; Humans | 2006 |
Control of plasma glucose with alpha-glucosidase inhibitor attenuates oxidative stress and slows the progression of heart failure in mice.
Topics: Acetophenones; Animals; Blotting, Western; Body Weight; Cells, Cultured; Disease Progression; Echoca | 2006 |
Abnormal glucose tolerance contributes to the progression of chronic heart failure in patients with dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Chronic Disease; Disease Progression; Echocardiography; Female; Glucose Int | 2006 |
Cerebral metabolic abnormalities in congestive heart failure detected by proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Echocardiography, Doppler; Exercise Test; | 1999 |
Are there different effects of acarbose and voglibose on serum levels of digoxin in a diabetic patient with congestive heart failure?
Topics: Acarbose; Aged; Aged, 80 and over; Cardiotonic Agents; Diabetes Mellitus, Type 2; Digoxin; Drug Inte | 2000 |
Correlation of cerebral metabolites with clinical outcome among patients with severe congestive heart failure.
Topics: Aspartic Acid; Brain; Choline; Cognition Disorders; Creatine; Disease Progression; Heart Failure; Hu | 2001 |