inositol has been researched along with Glucose Intolerance in 24 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because it reflects the current status of hyperglycemia, urinary myo-inositol (UMI) may be useful." | 7.80 | The utility of urinary myo-inositol as a marker of glucose intolerance. ( Furusyo, N; Hayashi, J; Hayashi, T; Ihara, T; Ikezaki, H; Kainuma, M; Murata, M; Ogawa, E; Okada, K, 2014) |
| " Myoinositol can be measured in urine and has been found to be elevated in patients with diabetes and glucose intolerance; it has thus proven useful as a marker for the early detection of these conditions." | 7.74 | Lucica MI urinary myoinositol kit: a new diagnostic test for diabetes mellitus and glucose intolerance. ( Kawazu, S; Yamakoshi, M, 2008) |
| "We measured urinary myo-inositol enzymatically before and 2 h after a 75-g oral glucose tolerance test in 564 volunteers, who were divided into four groups [normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes mellitus (DM)]." | 7.72 | A study of urinary myo-inositol as a sensitive marker of glucose intolerance. ( Katsura, Y; Kawazu, S; Kure, M; Matsuoka, T; Noritake, M; Sarashina, G; Shiomi, H; Takahashi, M; Tominaga, M; Tsuboi, I; Yamagata, F; Yamakoshi, M, 2004) |
| " We conclude that plasma levels of both pinitol and D-chiro-inositol are very responsive to pinitol ingestion, but insulin sensitivity does not increase after pinitol treatment in individuals with obesity and mild type 2 diabetes." | 5.09 | Effect of pinitol treatment on insulin action in subjects with insulin resistance. ( Christiansen, M; Davis, A; Hellerstein, MK; Horowitz, JF; Klein, S; Ostlund, RE, 2000) |
| " Because it reflects the current status of hyperglycemia, urinary myo-inositol (UMI) may be useful." | 3.80 | The utility of urinary myo-inositol as a marker of glucose intolerance. ( Furusyo, N; Hayashi, J; Hayashi, T; Ihara, T; Ikezaki, H; Kainuma, M; Murata, M; Ogawa, E; Okada, K, 2014) |
| " Myoinositol can be measured in urine and has been found to be elevated in patients with diabetes and glucose intolerance; it has thus proven useful as a marker for the early detection of these conditions." | 3.74 | Lucica MI urinary myoinositol kit: a new diagnostic test for diabetes mellitus and glucose intolerance. ( Kawazu, S; Yamakoshi, M, 2008) |
| "We measured urinary myo-inositol enzymatically before and 2 h after a 75-g oral glucose tolerance test in 564 volunteers, who were divided into four groups [normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes mellitus (DM)]." | 3.72 | A study of urinary myo-inositol as a sensitive marker of glucose intolerance. ( Katsura, Y; Kawazu, S; Kure, M; Matsuoka, T; Noritake, M; Sarashina, G; Shiomi, H; Takahashi, M; Tominaga, M; Tsuboi, I; Yamagata, F; Yamakoshi, M, 2004) |
| "Patients with type 2 diabetes mellitus (T2DM) have a higher incidence of cardiovascular (CV) events." | 2.87 | Effects of a Carob-Pod-Derived Sweetener on Glucose Metabolism. ( Badimon, L; Cubedo, J; Hernández-Mijares, A; Lambert, C; López-Bernal, S; Padró, T; Rocha, M; Vilahur, G, 2018) |
| "The increased prevalence of type 2 diabetes mellitus is a major concern for health providers." | 2.74 | Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance. ( Iwamoto, Y; Kaku, K; Kashiwagi, A; Kawamori, R; Shimamoto, K; Tajima, N, 2009) |
| "Since 1) dilated cardiomyopathy (DCM) causes chronic heart failure (CHF), and 2) augmentation of neurohumoral factors such as angiotensin II impairs glucose metabolism, we examined the rate of abnormal glucose metabolism in patients having both DCM and CHF and whether correction of the impairment of glucose metabolism would improve the pathophysiology of CHF in DCM patients." | 1.33 | Abnormal glucose tolerance contributes to the progression of chronic heart failure in patients with dilated cardiomyopathy. ( Asakura, M; Asanuma, H; Hashimura, K; Kanzaki, H; Kim, J; Kitakaze, M; Kokubo, Y; Komamura, K; Nakatani, S; Tomoike, H, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (45.83) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 4 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Plows, JF | 1 |
| Ramos Nieves, JM | 1 |
| Budin, F | 1 |
| Mace, K | 1 |
| Reynolds, CM | 1 |
| Vickers, MH | 1 |
| Silva-Zolezzi, I | 1 |
| Baker, PN | 1 |
| Stanley, JL | 1 |
| Takakado, M | 1 |
| Takata, Y | 1 |
| Yamagata, F | 3 |
| Yaguchi, M | 1 |
| Hiasa, G | 1 |
| Sato, S | 1 |
| Funada, JI | 1 |
| Kawazu, S | 4 |
| Osawa, H | 1 |
| Pericuesta, E | 1 |
| Laguna-Barraza, R | 1 |
| Ramos-Ibeas, P | 1 |
| Gutierrez-Arroyo, JL | 1 |
| Navarro, JA | 1 |
| Vera, K | 1 |
| Sanjuan, C | 1 |
| Baixeras, E | 1 |
| de Fonseca, FR | 1 |
| Gutierrez-Adan, A | 1 |
| Asakura, M | 2 |
| Kim, J | 2 |
| Asanuma, H | 2 |
| Hamasaki, T | 1 |
| Tsukahara, K | 1 |
| Higashino, Y | 1 |
| Ishikawa, T | 1 |
| Nakama, Y | 1 |
| Koba, S | 1 |
| Maruyama, Y | 1 |
| Tsujimoto, M | 1 |
| Himeno, H | 1 |
| Ohkusa, T | 1 |
| Fujino, S | 1 |
| Shimizu, M | 1 |
| Endo, T | 1 |
| Yoda, S | 1 |
| Muroya, T | 1 |
| Murohara, T | 1 |
| Ohte, N | 1 |
| Suzuki, H | 1 |
| Kohno, T | 1 |
| Fukui, K | 1 |
| Shiono, T | 1 |
| Takase, H | 1 |
| Uzui, H | 1 |
| Nagai, Y | 1 |
| Hashimoto, Y | 1 |
| Ikeda, S | 1 |
| Mizuno, S | 1 |
| Tamita, K | 1 |
| Fujita, M | 1 |
| Satake, K | 1 |
| Kinoshita, Y | 1 |
| Nunohiro, T | 1 |
| Sakagami, S | 1 |
| Higaki, J | 1 |
| Morii, I | 1 |
| Sawada, R | 1 |
| Hiasa, Y | 1 |
| Shigemasa, T | 1 |
| Nakahama, M | 1 |
| Sata, M | 1 |
| Doi, O | 1 |
| Ueda, T | 1 |
| Yamada, T | 1 |
| Yamanouchi, T | 1 |
| Yamaguchi, H | 1 |
| Morita, Y | 1 |
| Hayashi, H | 1 |
| Kitakaze, M | 2 |
| Lambert, C | 1 |
| Cubedo, J | 1 |
| Padró, T | 1 |
| Vilahur, G | 1 |
| López-Bernal, S | 1 |
| Rocha, M | 1 |
| Hernández-Mijares, A | 1 |
| Badimon, L | 1 |
| Donnarumma, M | 1 |
| Marasca, C | 1 |
| Palma, M | 1 |
| Vastarella, M | 1 |
| Annunziata, MC | 1 |
| Fabbrocini, G | 1 |
| Ortiz-Flores, AE | 1 |
| Luque-Ramírez, M | 1 |
| Escobar-Morreale, HF | 1 |
| Moelands, SV | 1 |
| Lucassen, PL | 1 |
| Akkermans, RP | 1 |
| De Grauw, WJ | 1 |
| Van de Laar, FA | 1 |
| Fried, PJ | 1 |
| Pascual-Leone, A | 1 |
| Bolo, NR | 1 |
| Ikezaki, H | 1 |
| Furusyo, N | 1 |
| Okada, K | 1 |
| Ihara, T | 1 |
| Hayashi, T | 1 |
| Ogawa, E | 1 |
| Kainuma, M | 1 |
| Murata, M | 1 |
| Hayashi, J | 1 |
| Kaku, K | 3 |
| Yamakoshi, M | 2 |
| Aoki, K | 1 |
| Ito, Y | 1 |
| Saito, K | 1 |
| Shirakawa, J | 1 |
| Togashi, Y | 1 |
| Satoh, K | 1 |
| Muraoka, T | 1 |
| Shinoda, K | 1 |
| Masuda, K | 1 |
| Kimura, M | 1 |
| Terauchi, Y | 1 |
| Kawamori, R | 3 |
| Tajima, N | 2 |
| Iwamoto, Y | 2 |
| Kashiwagi, A | 2 |
| Shimamoto, K | 2 |
| Scheen, AJ | 1 |
| Shen, H | 1 |
| Shao, M | 1 |
| Cho, KW | 1 |
| Wang, S | 1 |
| Chen, Z | 1 |
| Sheng, L | 1 |
| Wang, T | 1 |
| Liu, Y | 1 |
| Rui, L | 1 |
| Sarashina, G | 1 |
| Noritake, M | 1 |
| Takahashi, M | 1 |
| Kure, M | 1 |
| Katsura, Y | 1 |
| Shiomi, H | 1 |
| Tsuboi, I | 1 |
| Tominaga, M | 1 |
| Matsuoka, T | 1 |
| Nakamura, J | 1 |
| Nakatani, S | 1 |
| Hashimura, K | 1 |
| Komamura, K | 1 |
| Kanzaki, H | 1 |
| Kokubo, Y | 1 |
| Tomoike, H | 1 |
| Sundkvist, G | 1 |
| Dahlin, LB | 1 |
| Nilsson, H | 1 |
| Eriksson, KF | 1 |
| Lindgärde, F | 1 |
| Rosén, I | 1 |
| Lattimer, SA | 1 |
| Sima, AA | 1 |
| Sullivan, K | 1 |
| Greene, DA | 1 |
| Davis, A | 1 |
| Christiansen, M | 1 |
| Horowitz, JF | 1 |
| Klein, S | 1 |
| Hellerstein, MK | 1 |
| Ostlund, RE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Japan Working Group for the Assessment That the Alpha-glucosidase Inhibitor Blocks Cardiac Events in Patients With Myocardial Infarction and IGT[NCT00212017] | 3,000 participants (Actual) | Interventional | 2005-04-30 | Terminated (stopped due to We obtained the final results due to the interim analysis.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for inositol and Glucose Intolerance
| Article | Year |
|---|---|
Pharmacotherapeutic management of comorbid polycystic ovary syndrome and diabetes.
Topics: Animals; Diabetes Mellitus; Female; Glucose Intolerance; Humans; Inositol; Insulin; Insulin Resistan | 2018 |
Alpha-glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased risk of developing type 2 diabetes mellitus.
Topics: Acarbose; Blood Glucose; Cause of Death; Diabetes Mellitus, Type 2; Diet; Exercise; Fasting; Glucose | 2018 |
Efficacy of voglibose in type 2 diabetes.
Topics: Atherosclerosis; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Glucos | 2014 |
[Detection of glucose intolerance by urinary myo-inositol].
Topics: Biomarkers; Gas Chromatography-Mass Spectrometry; Glucose Intolerance; Humans; Inositol; Mass Screen | 2005 |
[Effects of voglibose, alpha-glucosidase inhibitor in treatment of impaired glucose tolerance].
Topics: Animals; Carbohydrate Metabolism; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucose Intolerance; | 2005 |
7 trials available for inositol and Glucose Intolerance
| Article | Year |
|---|---|
Does Treatment of Impaired Glucose Tolerance Improve Cardiovascular Outcomes in Patients with Previous Myocardial Infarction?
Topics: Aged; Cardiovascular Diseases; Female; Glucose Intolerance; Glycoside Hydrolase Inhibitors; Humans; | 2017 |
Effects of a Carob-Pod-Derived Sweetener on Glucose Metabolism.
Topics: Adolescent; Adult; Aged; Animals; Beverages; Blood Glucose; Body Mass Index; Complement C4a; Diabete | 2018 |
Comparison of pre- versus post-meal administration of voglibose in men with or without impaired glucose tolerance.
Topics: Adult; Area Under Curve; Blood Glucose; Cross-Over Studies; Drug Administration Schedule; Eating; Gl | 2009 |
Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance.
Topics: Administration, Oral; Analysis of Variance; Diabetes Mellitus, Type 2; Disease Progression; Double-B | 2009 |
[Alpha-glucosidase inhibitor for the prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese subjects with impaired glucose tolerance].
Topics: Asian People; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Disease Progression; Enzyme Inhibi | 2009 |
[Evidence demonstrating the effect of voglibose for the prevention of type 2 diabetes mellitus: a randomised double-blind trial in Japanese subjects with inpaired glucose tolerance].
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Intolerance; Humans; Hy | 2011 |
Effect of pinitol treatment on insulin action in subjects with insulin resistance.
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Cl | 2000 |
12 other studies available for inositol and Glucose Intolerance
| Article | Year |
|---|---|
The effects of myo-inositol and probiotic supplementation in a high-fat-fed preclinical model of glucose intolerance in pregnancy.
Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes, Gestational; Diet, High-Fat; Dietary Supplements; | 2020 |
Simple and non-invasive screening method for diabetes based on myoinositol levels in urine samples collected at home.
Topics: Adult; Aged; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Diagnostic Tests, Routine; Fastin | 2020 |
D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome.
Topics: Aging; Animals; Blastocyst; Cumulus Cells; Dihydrotestosterone; Disease Models, Animal; Female; Gene | 2020 |
An oral supplementation based on myo-inositol, folic acid and liposomal magnesium may act synergistically with antibiotic therapy and can improve metabolic profile in patients affected by Hidradenitis suppurativa: our experience.
Topics: Administration, Cutaneous; Administration, Oral; Anti-Bacterial Agents; Clindamycin; Dietary Supplem | 2020 |
Diabetes and the link between neuroplasticity and glutamate in the aging human motor cortex.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Creatine; Diabetes Mellitus, Type 2; Female; Glucose; | 2019 |
The utility of urinary myo-inositol as a marker of glucose intolerance.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Cross-Sectional Studies; Female; Glucose Intolerance; Glucos | 2014 |
Lucica MI urinary myoinositol kit: a new diagnostic test for diabetes mellitus and glucose intolerance.
Topics: Clinical Trials as Topic; Diabetes Mellitus; Glucose Intolerance; Glucose Tolerance Test; Humans; In | 2008 |
Voglibose for prevention of type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Glucose Intolerance; Humans; Hypoglycemic Agents; Inositol; Life Style; P | 2009 |
Herbal constituent sequoyitol improves hyperglycemia and glucose intolerance by targeting hepatocytes, adipocytes, and β-cells.
Topics: Adipocytes, White; Animals; Cell Line; Cells, Cultured; Diabetes Mellitus, Experimental; Female; Glu | 2012 |
A study of urinary myo-inositol as a sensitive marker of glucose intolerance.
Topics: Adult; Age Factors; Biomarkers; Case-Control Studies; Female; Glucose Intolerance; Humans; Inositol; | 2004 |
Abnormal glucose tolerance contributes to the progression of chronic heart failure in patients with dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Chronic Disease; Disease Progression; Echocardiography; Female; Glucose Int | 2006 |
Sorbitol and myo-inositol levels and morphology of sural nerve in relation to peripheral nerve function and clinical neuropathy in men with diabetic, impaired, and normal glucose tolerance.
Topics: Diabetes Mellitus, Type 1; Diabetic Neuropathies; Glucose Intolerance; Glucose Tolerance Test; Human | 2000 |