Page last updated: 2024-10-19

inositol and Gestational Hypertension

inositol has been researched along with Gestational Hypertension in 6 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
" Inclusion criteria were randomized controlled trials (RCTs) that enrolled overweight and obese pregnant women and used myo-inositol supplementation."9.41The Efficacy and Safety of Myo-inositol Supplementation for the Prevention of Gestational Diabetes Mellitus in Overweight and Obese Pregnant Women: A Systematic Review and Meta-Analysis. ( Corpuz, H; Factor, PA, 2023)
"Evidence from seven studies shows that antenatal dietary supplementation with myo-inositol during pregnancy may reduce the incidence of gestational diabetes, hypertensive disorders of pregnancy and preterm birth."5.41Antenatal dietary supplementation with myo-inositol for preventing gestational diabetes. ( Alsweiler, J; Crawford, TJ; Crowther, CA; Lin, L; Motuhifonua, SK, 2023)
" Inclusion criteria were randomized controlled trials (RCTs) that enrolled overweight and obese pregnant women and used myo-inositol supplementation."5.41The Efficacy and Safety of Myo-inositol Supplementation for the Prevention of Gestational Diabetes Mellitus in Overweight and Obese Pregnant Women: A Systematic Review and Meta-Analysis. ( Corpuz, H; Factor, PA, 2023)
"Myo-inositol treatment in early pregnancy is associated with a reduction in the rate of gestational diabetes mellitus and in the risk of preterm birth and macrosomia in women who are at risk for gestational diabetes mellitus."3.88Clinical and metabolic outcomes in pregnant women at risk for gestational diabetes mellitus supplemented with myo-inositol: a secondary analysis from 3 RCTs. ( Alibrandi, A; Corrado, F; D'Anna, R; Di Benedetto, A; Facchinetti, F; Pintaudi, B; Santamaria, A, 2018)
"Although gestational diabetes mellitus (GDM) has several short- and long-term adverse effects on the mother and the offspring, no medicine is generally prescribed to prevent GDM."3.01Myoinositols Prevent Gestational Diabetes Mellitus and Related Complications: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ( Ács, N; Greff, D; Hegyi, P; Horváth, EM; Nyirády, P; Park, S; Szinte, J; Váncsa, S; Váradi, A; Várbíró, S, 2023)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's4 (66.67)2.80

Authors

AuthorsStudies
Motuhifonua, SK1
Lin, L1
Alsweiler, J1
Crawford, TJ1
Crowther, CA1
Greff, D1
Váncsa, S1
Váradi, A1
Szinte, J1
Park, S1
Hegyi, P1
Nyirády, P1
Ács, N1
Horváth, EM1
Várbíró, S1
Factor, PA1
Corpuz, H1
Arishe, OO1
Ebeigbe, AB1
Webb, RC1
Santamaria, A2
Alibrandi, A1
Di Benedetto, A1
Pintaudi, B1
Corrado, F2
Facchinetti, F1
D'Anna, R2
Baviera, G1
Carlomagno, G1
Unfer, V1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Myoinositol on Serum Asprosin Levels in Pregnant Women[NCT05943158]40 participants (Actual)Interventional2021-06-01Completed
Myoinositol Supplementation, Insulin Resistance and Fetal Sonographic Parameters in Gestational Diabetes, Diet Treated: a Prospective, Randomized, Placebo-controlled Study[NCT03763669]120 participants (Actual)Interventional2018-11-14Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for inositol and Gestational Hypertension

ArticleYear
Antenatal dietary supplementation with myo-inositol for preventing gestational diabetes.
    The Cochrane database of systematic reviews, 2023, 02-15, Volume: 2

    Topics: Adult; Diabetes Mellitus, Type 2; Diabetes, Gestational; Dietary Supplements; Female; Humans; Hypert

2023
Myoinositols Prevent Gestational Diabetes Mellitus and Related Complications: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Nutrients, 2023, Sep-30, Volume: 15, Issue:19

    Topics: Diabetes, Gestational; Female; Humans; Hypertension, Pregnancy-Induced; Hypoglycemia; Infant, Newbor

2023
The Efficacy and Safety of Myo-inositol Supplementation for the Prevention of Gestational Diabetes Mellitus in Overweight and Obese Pregnant Women: A Systematic Review and Meta-Analysis.
    Journal of the ASEAN Federation of Endocrine Societies, 2023, Volume: 38, Issue:2

    Topics: Diabetes, Gestational; Dietary Supplements; Female; Humans; Hypertension, Pregnancy-Induced; Infant,

2023

Other Studies

3 other studies available for inositol and Gestational Hypertension

ArticleYear
Use of a Combination of Insulin Sensitizers and Antioxidant Supplements in the Management of Pregnancy Hypertensive Disorders.
    American journal of hypertension, 2020, 07-18, Volume: 33, Issue:7

    Topics: Animals; Antioxidants; Dietary Supplements; Female; Humans; Hypertension, Pregnancy-Induced; Inosito

2020
Clinical and metabolic outcomes in pregnant women at risk for gestational diabetes mellitus supplemented with myo-inositol: a secondary analysis from 3 RCTs.
    American journal of obstetrics and gynecology, 2018, Volume: 219, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 2; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth R

2018
Second trimester amniotic fluid myo-inositol concentrations in women later developing gestational diabetes mellitus or pregnancy-induced hypertension.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2016, Volume: 29, Issue:14

    Topics: Adult; Amniotic Fluid; Case-Control Studies; Diabetes, Gestational; Female; Humans; Hypertension, Pr

2016