Page last updated: 2024-10-19

inositol and Folic Acid Deficiency

inositol has been researched along with Folic Acid Deficiency in 2 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)

Research Excerpts

ExcerptRelevanceReference
" Maternal periconceptional supplementation with folic acid significantly reduces the risk of an NTD-affected pregnancy, but does not prevent all NTDs, and "folic acid non-responsive" NTDs continue to occur."8.95Inositol, neural tube closure and the prevention of neural tube defects. ( Copp, AJ; Greene, ND; Leung, KY, 2017)
" Maternal periconceptional supplementation with folic acid significantly reduces the risk of an NTD-affected pregnancy, but does not prevent all NTDs, and "folic acid non-responsive" NTDs continue to occur."4.95Inositol, neural tube closure and the prevention of neural tube defects. ( Copp, AJ; Greene, ND; Leung, KY, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greene, ND2
Leung, KY1
Copp, AJ2
Burren, KA1
Scott, JM1

Reviews

1 review available for inositol and Folic Acid Deficiency

ArticleYear
Inositol, neural tube closure and the prevention of neural tube defects.
    Birth defects research, 2017, 01-30, Volume: 109, Issue:2

    Topics: Animals; Clinical Trials as Topic; Dietary Supplements; Disease Models, Animal; Female; Folic Acid;

2017

Other Studies

1 other study available for inositol and Folic Acid Deficiency

ArticleYear
The genetic background of the curly tail strain confers susceptibility to folate-deficiency-induced exencephaly.
    Birth defects research. Part A, Clinical and molecular teratology, 2010, Volume: 88, Issue:2

    Topics: Animals; Diet; DNA-Binding Proteins; Female; Folic Acid; Folic Acid Deficiency; Genetic Predispositi

2010