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inositol and Fetal Growth Retardation

inositol has been researched along with Fetal Growth Retardation in 13 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Fetal Growth Retardation: Failure of a FETUS to attain expected GROWTH.

Research Excerpts

ExcerptRelevanceReference
"Myo-inositol treatment in early pregnancy is associated with a reduction in the rate of gestational diabetes mellitus and in the risk of preterm birth and macrosomia in women who are at risk for gestational diabetes mellitus."3.88Clinical and metabolic outcomes in pregnant women at risk for gestational diabetes mellitus supplemented with myo-inositol: a secondary analysis from 3 RCTs. ( Alibrandi, A; Corrado, F; D'Anna, R; Di Benedetto, A; Facchinetti, F; Pintaudi, B; Santamaria, A, 2018)
"Inositol is a cyclic sugar alcohol which occurs naturally in a variety of stereoisomers, the most common of which is myo-inositol."2.49Myoinositol: a new marker of intrauterine growth restriction? ( Dessì, A; Fanos, V, 2013)
"A total of 26 prematurely born intrauterine growth restriction infants (birthweight <10th centile for gestational age), 22 prematurely born but adequate for gestational age controls, and 26 term adequate-for-gestational-age infants underwent brain magnetic resonance imaging and magnetic resonance spectroscopy at 1 year of age during natural sleep, on a 3 Tesla scanner."1.46Brain metabolite alterations in infants born preterm with intrauterine growth restriction: association with structural changes and neurodevelopmental outcome. ( Bargalló, N; Cruz-Lemini, M; Eixarch, E; Gratacós, E; Muñoz-Moreno, E; Sanz-Cortés, M; Simões, RV, 2017)
"The subgroup with late intrauterine growth restriction further showed lower estimated glutathione levels at age 1 year."1.42Brain metabolite differences in one-year-old infants born small at term and association with neurodevelopmental outcome. ( Bargalló, N; Cruz-Lemini, M; Gratacós, E; Sanz-Cortés, M; Simões, RV, 2015)
"Myo-inositol (Myo-ins) is a marker of neuroglial cells, being present in the astrocytes of brain tissue, but also functions as an osmolyte."1.39Myo-inositol metabolism in appropriately grown and growth-restricted fetuses: a proton magnetic resonance spectroscopy study. ( Allsop, JM; Damodaram, MS; Kumar, S; Mcguinness, A; Patel, A; Rutherford, MA; Story, L; Supramaniam, V; Wylezinska, M, 2013)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's1 (7.69)18.2507
2000's0 (0.00)29.6817
2010's11 (84.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santamaria, A1
Alibrandi, A1
Di Benedetto, A1
Pintaudi, B1
Corrado, F1
Facchinetti, F1
D'Anna, R1
Story, L1
Damodaram, MS1
Supramaniam, V1
Allsop, JM1
Mcguinness, A1
Patel, A1
Wylezinska, M1
Kumar, S1
Rutherford, MA1
Dessì, A2
Fanos, V2
Metges, CC1
Görs, S1
Lang, IS1
Hammon, HM1
Brüssow, KP1
Weitzel, JM1
Nürnberg, G1
Rehfeldt, C1
Otten, W1
Barberini, L1
Noto, A1
Fattuoni, C1
Grapov, D1
Casanova, A1
Fenu, G1
Gaviano, M1
Carboni, R1
Ottonello, G1
Crisafulli, M1
Simões, RV2
Cruz-Lemini, M2
Bargalló, N2
Gratacós, E2
Sanz-Cortés, M2
Muñoz-Moreno, E1
Eixarch, E1
Regnault, TR1
Teng, C1
de Vrijer, B1
Galan, HL2
Wilkening, RB1
Battaglia, FC2
Nissen, PM1
Nebel, C1
Oksbjerg, N1
Bertram, HC1
Arroyo, JA1
Garcia-Jones, P1
Graham, A1
Teng, CC1
Berger-Kulemann, V1
Brugger, PC1
Pugash, D1
Krssak, M1
Weber, M1
Wielandner, A1
Prayer, D1
Hallman, M1
Wermer, D1
Epstein, BL1
Gluck, L1
Cortey, A1
Jarvik, JG1
Lenkinski, RE1
Grossman, RI1
Frank, I1
Delivoria-Papadopoulos, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Myoinositol Supplementation, Insulin Resistance and Fetal Sonographic Parameters in Gestational Diabetes, Diet Treated: a Prospective, Randomized, Placebo-controlled Study[NCT03763669]120 participants (Actual)Interventional2018-11-14Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for inositol and Fetal Growth Retardation

ArticleYear
Myoinositol: a new marker of intrauterine growth restriction?
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2013, Volume: 33, Issue:8

    Topics: Biomarkers; Female; Fetal Growth Retardation; Humans; Inositol; Pregnancy

2013

Other Studies

12 other studies available for inositol and Fetal Growth Retardation

ArticleYear
Clinical and metabolic outcomes in pregnant women at risk for gestational diabetes mellitus supplemented with myo-inositol: a secondary analysis from 3 RCTs.
    American journal of obstetrics and gynecology, 2018, Volume: 219, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 2; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth R

2018
Myo-inositol metabolism in appropriately grown and growth-restricted fetuses: a proton magnetic resonance spectroscopy study.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 170, Issue:1

    Topics: Astrocytes; Brain; Case-Control Studies; Creatine; Female; Fetal Growth Retardation; Fetus; Humans;

2013
Low and high dietary protein:carbohydrate ratios during pregnancy affect materno-fetal glucose metabolism in pigs.
    The Journal of nutrition, 2014, Volume: 144, Issue:2

    Topics: Adaptation, Physiological; Animals; Area Under Curve; Blood Glucose; Brain; Diet; Diet, Carbohydrate

2014
Urinary metabolomics (GC-MS) reveals that low and high birth weight infants share elevated inositol concentrations at birth.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2014, Volume: 27 Suppl 2

    Topics: Biomarkers; Birth Weight; Female; Fetal Growth Retardation; Gas Chromatography-Mass Spectrometry; Ge

2014
Brain metabolite differences in one-year-old infants born small at term and association with neurodevelopmental outcome.
    American journal of obstetrics and gynecology, 2015, Volume: 213, Issue:2

    Topics: Adaptation, Psychological; Aspartic Acid; Brain; Child Development; Child, Preschool; Cognition; Cre

2015
Brain metabolite alterations in infants born preterm with intrauterine growth restriction: association with structural changes and neurodevelopmental outcome.
    American journal of obstetrics and gynecology, 2017, Volume: 216, Issue:1

    Topics: Adaptation, Psychological; Anisotropy; Aspartic Acid; Brain; Child, Preschool; Choline; Cognition; C

2017
The tissue and plasma concentration of polyols and sugars in sheep intrauterine growth retardation.
    Experimental biology and medicine (Maywood, N.J.), 2010, Volume: 235, Issue:8

    Topics: Animals; Carbohydrate Metabolism; Carbohydrates; Female; Fetal Growth Retardation; Fetus; Fructose;

2010
Metabolomics reveals relationship between plasma inositols and birth weight: possible markers for fetal programming of type 2 diabetes.
    Journal of biomedicine & biotechnology, 2011, Volume: 2011

    Topics: Animals; Biomarkers; Birth Weight; Diabetes Mellitus, Type 2; Female; Fetal Growth Retardation; Gas

2011
Placental TonEBP/NFAT5 osmolyte regulation in an ovine model of intrauterine growth restriction.
    Biology of reproduction, 2012, Volume: 86, Issue:3

    Topics: Aldehyde Reductase; Animals; Female; Fetal Growth Retardation; Inositol; Models, Animal; NADP; NFATC

2012
MR spectroscopy of the fetal brain: is it possible without sedation?
    AJNR. American journal of neuroradiology, 2013, Volume: 34, Issue:2

    Topics: Aspartic Acid; Brain; Choline; Conscious Sedation; Creatine; Female; Fetal Diseases; Fetal Growth Re

2013
Effects of maternal insulin or glucose infusion on the fetus: study on lung surfactant phospholipids, plasma myoinositol, and fetal growth in the rabbit.
    American journal of obstetrics and gynecology, 1982, Apr-01, Volume: 142, Issue:7

    Topics: Animals; Blood Glucose; Female; Fetal Growth Retardation; Fetal Organ Maturity; Fetus; Glucose; Infu

1982
Proton MR spectroscopy of brain abnormalities in neonates born to HIV-positive mothers.
    AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:10

    Topics: AIDS Dementia Complex; Aspartic Acid; Choline; Diagnosis, Differential; Energy Metabolism; Female; F

1994