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inositol and Experimental Mammary Neoplasms

inositol has been researched along with Experimental Mammary Neoplasms in 8 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
" Toxicity studies allowed us to establish the LD50 (750 mg/kg body weight)."1.30A synthetic, nitrogenated antimetastatic and anti-angiogenic compound with low toxicity in vivo. ( Cerutti, ML; Colombo, L; D'Orio, E; Davel, L; Diament, M; Eiján, AM; Gelpi, ME; Leicach, SR; Parma, P; Stillitani, I, 1999)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rengarajan, T2
Nandakumar, N2
Rajendran, P1
Ganesh, MK1
Balasubramanian, MP2
Nishigaki, I1
Vucenik, I1
Yang, GY1
Shamsuddin, AM1
Eiján, AM2
Puricelli, L1
Bal de Kier Joffé, E1
Elías, C1
Leicach, SR2
Cadenas, RA1
Cerutti, ML1
D'Orio, E1
Davel, L1
Colombo, L1
Parma, P1
Diament, M1
Stillitani, I1
Gelpi, ME1
Narayanan, U1
Hilf, R1
Monaco, ME1
Adelson, JR1
Tanino, T1
Narumi, K1
Tsumita, T1

Other Studies

8 other studies available for inositol and Experimental Mammary Neoplasms

ArticleYear
D-pinitol mitigates tumor growth by modulating interleukins and hormones and induces apoptosis in rat breast carcinogenesis through inhibition of NF-κB.
    Journal of physiology and biochemistry, 2015, Volume: 71, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Prot

2015
D-Pinitol attenuates 7, 12 dimethylbenz [a] anthracene induced hazards through modulating protein bound carbohydrates, adenosine triphosphatases and lysosomal enzymes during experimental mammary carcinogenesis.
    Journal of experimental therapeutics & oncology, 2012, Volume: 10, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosine Triphosphatases; Animals; Breast; Carcinogens, Environme

2012
Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer.
    Carcinogenesis, 1995, Volume: 16, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Bone and Bones; Female; Inositol

1995
Action of nitrogenated and sulfonylated inositol derivatives upon the proliferation in vitro of normal mouse cells and tumor mouse cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1994, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Survival; Cells, Cul

1994
A synthetic, nitrogenated antimetastatic and anti-angiogenic compound with low toxicity in vivo.
    International journal of oncology, 1999, Volume: 14, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Fem

1999
Effects of diabetes and insulin on phosphoinositide metabolism in R3230AC mammary tumors.
    Cancer biochemistry biophysics, 1992, Volume: 13, Issue:2

    Topics: Adenocarcinoma; Animals; Biological Transport, Active; Diabetes Mellitus, Experimental; Female; Inos

1992
Evidence for coupling of resynthesis to hydrolysis in the phosphoinositide cycle.
    The Biochemical journal, 1991, Oct-15, Volume: 279 ( Pt 2)

    Topics: Animals; Chlorides; Hydrolysis; Inositol; Inositol Phosphates; Lithium; Lithium Chloride; Mammary Ne

1991
Studies on tumor-host relationship. V. Effect of myo-inositol on tumor cell growth in vivo and on the resistant activity of the host.
    The Japanese journal of experimental medicine, 1972, Volume: 42, Issue:6

    Topics: Animals; Ascites; Female; Inositol; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mitosis

1972