inositol has been researched along with Epilepsy, Tonic-Clonic in 4 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
Excerpt | Relevance | Reference |
---|---|---|
"Valproate (VPA) interferes with mitochondrial metabolism causing hyperammonemia, thereby shifting the balance reaction of glutamine (Gln)/glutamate (Glu) toward Gln." | 3.75 | Valproate-induced metabolic changes in patients with epilepsy: assessment with H-MRS. ( Buechert, M; Garcia, M; Huppertz, HJ; Mader, I; Schumacher, M; Ziyeh, S, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Garcia, M | 1 |
Huppertz, HJ | 1 |
Ziyeh, S | 1 |
Buechert, M | 1 |
Schumacher, M | 1 |
Mader, I | 1 |
Doelken, MT | 1 |
Mennecke, A | 1 |
Stadlbauer, A | 1 |
Kecskeméti, L | 1 |
Kasper, BS | 1 |
Struffert, T | 1 |
Doerfler, A | 1 |
Stefan, H | 1 |
Hammen, T | 1 |
Savic, I | 1 |
Osterman, Y | 1 |
Helms, G | 1 |
Kofman, O | 1 |
Sherman, WR | 1 |
Katz, V | 1 |
Belmaker, RH | 1 |
4 other studies available for inositol and Epilepsy, Tonic-Clonic
Article | Year |
---|---|
Valproate-induced metabolic changes in patients with epilepsy: assessment with H-MRS.
Topics: Adolescent; Adult; Anticonvulsants; Aspartic Acid; Choline; Creatine; Energy Metabolism; Epilepsies, | 2009 |
Multi-voxel magnetic resonance spectroscopy at 3 T in patients with idiopathic generalised epilepsy.
Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Brain; Cerebral Cortex; Choline; Creatine; Epilepsy | 2010 |
MRS shows syndrome differentiated metabolite changes in human-generalized epilepsies.
Topics: Adolescent; Adult; Aspartic Acid; Cerebellum; Cerebral Cortex; Choline; Creatine; Dominance, Cerebra | 2004 |
Restoration of brain myo-inositol levels in rats increases latency to lithium-pilocarpine seizures.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Epilepsy, Tonic-Clonic; Injections, Int | 1993 |