inositol has been researched along with Epilepsy, Temporal Lobe in 7 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to quantitate and compare ipsilateral total N-acetyl aspartate (tNAA), creatine (Cr), choline (Cho), myo-inositol (m-Ins) and glutamate plus glutamine (Glx) levels in the hippocampi of patients with temporal lobe epilepsy (TLE) with and without magnetic resonance imaging (MRI) evidence for mesial temporal sclerosis (MRI positive/negative)." | 3.74 | (1)H-MRS profile in MRI positive- versus MRI negative patients with temporal lobe epilepsy. ( Doelken, MT; Doerfler, A; Engelhorn, T; Ganslandt, O; Hammen, T; Pauli, E; Richter, G; Stadlbauer, A; Stefan, H; Struffert, T, 2008) |
| "Mesial temporal lobe epilepsy (mTLE) is characterized by hippocampal atrophy, decreased N-acetyl-aspartate, and a low N-acetyl-aspartate/total creatine ratio, often attributed to neuron loss and gliosis." | 3.72 | N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus. ( Errante, LD; Kim, JH; Petroff, OA; Spencer, DD, 2003) |
| "We investigated myoinositol in TLE by using short-echo MRS in 34 TLE patients [26 late onset (LO-TLE), eight hippocampal sclerosis (HS-TLE)], and 16 controls." | 3.72 | Myoinositol abnormalities in temporal lobe epilepsy. ( Briellmann, RS; Jackson, GD; Prichard, JW; Syngeniotis, A; Wellard, RM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Pimentel-Silva, LR | 1 |
| Casseb, RF | 1 |
| Cordeiro, MM | 1 |
| Campos, BAG | 1 |
| Alvim, MKM | 1 |
| Rogerio, F | 1 |
| Yasuda, CL | 1 |
| Cendes, F | 1 |
| Wu, Y | 1 |
| Pearce, PS | 1 |
| Rapuano, A | 1 |
| Hitchens, TK | 1 |
| de Lanerolle, NC | 1 |
| Pan, JW | 1 |
| Petroff, OA | 1 |
| Errante, LD | 1 |
| Kim, JH | 1 |
| Spencer, DD | 1 |
| Wellard, RM | 1 |
| Briellmann, RS | 1 |
| Prichard, JW | 1 |
| Syngeniotis, A | 1 |
| Jackson, GD | 1 |
| Mueller, SG | 1 |
| Laxer, KD | 1 |
| Suhy, J | 1 |
| Lopez, RC | 1 |
| Flenniken, DL | 1 |
| Weiner, MW | 1 |
| Riederer, F | 1 |
| Bittsanský, M | 1 |
| Schmidt, C | 1 |
| Mlynárik, V | 1 |
| Baumgartner, C | 1 |
| Moser, E | 1 |
| Serles, W | 1 |
| Doelken, MT | 1 |
| Stefan, H | 1 |
| Pauli, E | 1 |
| Stadlbauer, A | 1 |
| Struffert, T | 1 |
| Engelhorn, T | 1 |
| Richter, G | 1 |
| Ganslandt, O | 1 |
| Doerfler, A | 1 |
| Hammen, T | 1 |
7 other studies available for inositol and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Interactions between in vivo neuronal-glial markers, side of hippocampal sclerosis, and pharmacoresponse in temporal lobe epilepsy.
Topics: Adult; Anticonvulsants; Biomarkers; Case-Control Studies; Creatine; Drug Resistant Epilepsy; Epileps | 2020 |
Metabolic changes in early poststatus epilepticus measured by MR spectroscopy in rats.
Topics: Animals; Antigens, Nuclear; Aspartic Acid; Brain Chemistry; Creatine; Epilepsy, Temporal Lobe; Gluta | 2015 |
N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus.
Topics: Adolescent; Adult; Anterior Temporal Lobectomy; Aspartic Acid; Atrophy; Creatine; Epilepsy, Temporal | 2003 |
Myoinositol abnormalities in temporal lobe epilepsy.
Topics: Adult; Age of Onset; Aspartic Acid; Epilepsy, Temporal Lobe; Female; Frontal Lobe; Functional Latera | 2003 |
Spectroscopic metabolic abnormalities in mTLE with and without MRI evidence for mesial temporal sclerosis using hippocampal short-TE MRSI.
Topics: Adult; Aspartic Acid; Choline; Creatine; Diagnosis, Differential; Dominance, Cerebral; Energy Metabo | 2003 |
1H magnetic resonance spectroscopy at 3 T in cryptogenic and mesial temporal lobe epilepsy.
Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Glutamic Acid; Glutamine; | 2006 |
(1)H-MRS profile in MRI positive- versus MRI negative patients with temporal lobe epilepsy.
Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Electroencephalography; Epilepsy, Temporal Lob | 2008 |