inositol has been researched along with Disease Exacerbation in 67 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The beneficial effects obtained by myo-inositol in association with seleno-methionine in patients affected by subclinical hypothyroidism have been recently demonstrated." | 9.24 | Myo-inositol and selenium reduce the risk of developing overt hypothyroidism in patients with autoimmune thyroiditis. ( Antonelli, A; Benvenga, S; Di Bari, F; Fallahi, P; Ferrari, SM; Vita, R, 2017) |
| "Adult-onset type II citrullinemia is an inborn error of urea cycle metabolism that can lead to hyperammonemic encephalopathy and coma." | 7.74 | Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients. ( Au, WL; Lim, CC; Wong, YC; Xu, M; Ye, J, 2007) |
| "The beneficial effects obtained by myo-inositol in association with seleno-methionine in patients affected by subclinical hypothyroidism have been recently demonstrated." | 5.24 | Myo-inositol and selenium reduce the risk of developing overt hypothyroidism in patients with autoimmune thyroiditis. ( Antonelli, A; Benvenga, S; Di Bari, F; Fallahi, P; Ferrari, SM; Vita, R, 2017) |
| "Adult-onset type II citrullinemia is an inborn error of urea cycle metabolism that can lead to hyperammonemic encephalopathy and coma." | 3.74 | Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients. ( Au, WL; Lim, CC; Wong, YC; Xu, M; Ye, J, 2007) |
| " Cerebral MRI shows hypomyelinated white matter and cerebellar atrophy; 1H-MRS of white matter reveals a marked elevation of myo-inositol." | 3.73 | Leukoencephalopathy with ataxia, hypodontia, and hypomyelination. ( Boltshauser, E; Ebinger, F; Harting, I; Hoffmann, GF; Koch, MJ; Martin, E; Rating, D; Schmitt-Mechelke, T; Uhlenberg, B; Weber, L; Wiegand, G; Wolf, NI; Zschocke, J, 2005) |
| " Strongly elevated concentrations of myo-inositol in conjunction with normal or increased choline-containing compounds in all regions investigated point to astrocytosis and demyelination." | 3.72 | Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease. ( Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Haupt, M; Meins, M; Sperner, J; Stephani, U, 2003) |
| " We also did not find a correlation between the amount of Glx and the initial Glasgow Coma Scale score, duration of coma, nor with changes in spectral metabolites, including N-acetyl aspartate, choline, and myoinositol." | 3.72 | Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury. ( Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K, 2004) |
| "The increased prevalence of type 2 diabetes mellitus is a major concern for health providers." | 2.74 | Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance. ( Iwamoto, Y; Kaku, K; Kashiwagi, A; Kawamori, R; Shimamoto, K; Tajima, N, 2009) |
| "To evaluate the mechanisms underlying disease progression in the early phase of PPMS by measuring metabolite concentrations in normal-appearing white matter (NAWM) and cortical gray matter (CGM) and to assess their relationship with clinical outcomes." | 2.71 | Metabolite changes in normal-appearing gray and white matter are linked with disability in early primary progressive multiple sclerosis. ( Chard, DT; Ingle, GT; McLean, MA; Miller, DH; Ramió-Torrentà, L; Sastre-Garriga, J; Thompson, AJ, 2005) |
| "Disease progression was investigated at 4 time points, from 9 to 18 months of age, and in 4 regions: cortex, hippocampus, striatum, and thalamus." | 1.72 | Spatio-temporal metabolic rewiring in the brain of TgF344-AD rat model of Alzheimer's disease. ( López-Gil, X; Muñoz-Moreno, E; Simões, RV; Soria, G; Tudela, R, 2022) |
| "Factors associated with disease progression despite optimal glucose control remain to be elucidated." | 1.40 | Clinical predictors of atheroma progression despite optimal glycemic control in early-stage diabetic patients with coronary artery disease: Insight from the DIANA study. ( Kataoka, Y; Kimura, K; Kosuge, M; Miyamoto, Y; Miyazaki, S; Sase, K; Yasuda, S; Yoshimasa, Y, 2014) |
| "Atherosclerosis is a multifactorial and progressive disease commonly correlated with a high fat diet." | 1.40 | Serum metabonomic analysis of apoE(-/-) mice reveals progression axes for atherosclerosis based on NMR spectroscopy. ( Guo, J; Li, J; Li, X; Liu, Y; Wang, L; Wu, T; Yang, Y; Yuan, F; Zhang, Q; Zheng, L, 2014) |
| "Neurological involvement in X-linked mucopolysaccharidosis type II (Hunter syndrome) is indicative of more severe disease, but is not attenuated by current enzyme replacement therapy which does not significantly penetrate the blood-brain barrier." | 1.36 | Quantitative in vivo brain magnetic resonance spectroscopic monitoring of neurological involvement in mucopolysaccharidosis type II (Hunter Syndrome). ( Davies, NP; Davison, JE; Gissen, P; Hendriksz, CJ; Peet, AC; Sun, Y, 2010) |
| "Prion diseases are fatal chronic neurodegenerative diseases." | 1.34 | MRI and MRS alterations in the preclinical phase of murine prion disease: association with neuropathological and behavioural changes. ( Anthony, DC; Blamire, AM; Broom, KA; Griffin, JL; Lowe, JP; Perry, VH; Scott, H; Sibson, NR; Styles, P, 2007) |
| "To analyze whether survival and disease progression in patients with ALS have changed during the past 20 years." | 1.33 | Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing? ( Appel, SH; Czaplinski, A; Simpson, EP; Yen, AA, 2006) |
| "Since 1) dilated cardiomyopathy (DCM) causes chronic heart failure (CHF), and 2) augmentation of neurohumoral factors such as angiotensin II impairs glucose metabolism, we examined the rate of abnormal glucose metabolism in patients having both DCM and CHF and whether correction of the impairment of glucose metabolism would improve the pathophysiology of CHF in DCM patients." | 1.33 | Abnormal glucose tolerance contributes to the progression of chronic heart failure in patients with dilated cardiomyopathy. ( Asakura, M; Asanuma, H; Hashimura, K; Kanzaki, H; Kim, J; Kitakaze, M; Kokubo, Y; Komamura, K; Nakatani, S; Tomoike, H, 2006) |
| "Pretreatment with pargyline attenuated the MPTP-induced clinical signs, MRI and MRS changes, and the histopathological and immunoreactivity alterations." | 1.32 | Proton magnetic resonance imaging and spectroscopy identify metabolic changes in the striatum in the MPTP feline model of parkinsonism. ( Hadjiconstantinou, M; Neff, NH; Podell, M; Smith, MA, 2003) |
| "The fulminating form of subacute sclerosing panencephalitis is an extremely rare condition." | 1.32 | Subacute sclerosing panencephalitis with fulminating course: follow-up magnetic resonance spectroscopy (MRS) findings. ( Alkan, A; Aslan, M; Kutlu, R; Sarac, K; Sigirci, A; Yakinci, C, 2004) |
| "The metabolic disturbances indicate disease progression but are less pronounced than in older patients with hemimegalencephaly." | 1.30 | Proton magnetic resonance spectroscopy of linear nevus sebaceus syndrome. ( Christen, HJ; Frahm, J; Hanefeld, FA; Kruse, B; Pouwels, PJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (4.48) | 18.2507 |
| 2000's | 36 (53.73) | 29.6817 |
| 2010's | 22 (32.84) | 24.3611 |
| 2020's | 6 (8.96) | 2.80 |
| Authors | Studies |
|---|---|
| Dekker, SEI | 1 |
| Verhoeven, A | 1 |
| Frey, D | 1 |
| Soonawala, D | 1 |
| Peters, DJM | 1 |
| Mayboroda, OA | 1 |
| de Fijter, JW | 1 |
| Muñoz-Moreno, E | 1 |
| Simões, RV | 1 |
| Tudela, R | 1 |
| López-Gil, X | 1 |
| Soria, G | 1 |
| Blicher, JU | 1 |
| Eskildsen, SF | 1 |
| Stærmose, TG | 1 |
| Møller, AT | 1 |
| Figlewski, K | 1 |
| Near, J | 1 |
| Pace, C | 1 |
| Tumino, D | 1 |
| Russo, M | 1 |
| Le Moli, R | 1 |
| Naselli, A | 1 |
| Borzì, G | 1 |
| Malandrino, P | 1 |
| Frasca, F | 1 |
| Laganà, AS | 1 |
| Unfer, V | 1 |
| Garzon, S | 1 |
| Bizzarri, M | 1 |
| Rackayová, V | 1 |
| Flatt, E | 1 |
| Braissant, O | 1 |
| Grosse, J | 1 |
| Capobianco, D | 1 |
| Mastromarino, P | 1 |
| McMillin, M | 1 |
| DeMorrow, S | 1 |
| McLin, VA | 1 |
| Cudalbu, C | 1 |
| Hanafy, MM | 1 |
| Lindeque, JZ | 1 |
| El-Maraghy, SA | 1 |
| Abdel-Hamid, AZ | 1 |
| Shahin, NN | 1 |
| Kirov, II | 1 |
| Liu, S | 1 |
| Tal, A | 1 |
| Wu, WE | 1 |
| Davitz, MS | 1 |
| Babb, JS | 1 |
| Rusinek, H | 1 |
| Herbert, J | 1 |
| Gonen, O | 1 |
| Ferrari, SM | 1 |
| Fallahi, P | 1 |
| Di Bari, F | 1 |
| Vita, R | 1 |
| Benvenga, S | 1 |
| Antonelli, A | 1 |
| Waragai, M | 1 |
| Moriya, M | 1 |
| Nojo, T | 1 |
| Joers, JM | 1 |
| Deelchand, DK | 1 |
| Lyu, T | 1 |
| Emir, UE | 1 |
| Hutter, D | 1 |
| Gomez, CM | 1 |
| Bushara, KO | 1 |
| Eberly, LE | 1 |
| Öz, G | 2 |
| Ferrer, MD | 1 |
| Ketteler, M | 1 |
| Tur, F | 1 |
| Tur, E | 1 |
| Isern, B | 1 |
| Salcedo, C | 1 |
| Joubert, PH | 1 |
| Behets, GJ | 1 |
| Neven, E | 1 |
| D'Haese, PC | 1 |
| Perelló, J | 1 |
| Weerasekera, A | 1 |
| Peeters, R | 1 |
| Sima, D | 1 |
| Dresselaers, T | 1 |
| Sunaert, S | 1 |
| De Vocht, J | 1 |
| Claeys, K | 1 |
| Van Huffel, S | 1 |
| Van Damme, P | 1 |
| Himmelreich, U | 1 |
| Kantarci, K | 2 |
| Gongvatana, A | 1 |
| Harezlak, J | 1 |
| Buchthal, S | 1 |
| Daar, E | 1 |
| Schifitto, G | 1 |
| Campbell, T | 1 |
| Taylor, M | 1 |
| Singer, E | 1 |
| Algers, J | 1 |
| Zhong, J | 1 |
| Brown, M | 1 |
| McMahon, D | 1 |
| So, YT | 1 |
| Mi, D | 1 |
| Heaton, R | 1 |
| Robertson, K | 1 |
| Yiannoutsos, C | 1 |
| Cohen, RA | 1 |
| Navia, B | 1 |
| Targosz-Gajniak, MG | 1 |
| Siuda, JS | 1 |
| Wicher, MM | 1 |
| Banasik, TJ | 1 |
| Bujak, MA | 1 |
| Augusciak-Duma, AM | 1 |
| Opala, G | 1 |
| Bruggers, CS | 1 |
| Moore, K | 1 |
| Kataoka, Y | 1 |
| Yasuda, S | 1 |
| Miyamoto, Y | 1 |
| Sase, K | 1 |
| Kosuge, M | 1 |
| Kimura, K | 1 |
| Yoshimasa, Y | 1 |
| Miyazaki, S | 1 |
| Lin, Y | 1 |
| Yao, J | 1 |
| Chen, Y | 1 |
| Pang, L | 1 |
| Li, H | 1 |
| Cao, Z | 1 |
| You, K | 1 |
| Dai, H | 1 |
| Wu, R | 1 |
| Llufriu, S | 1 |
| Kornak, J | 1 |
| Ratiney, H | 1 |
| Oh, J | 1 |
| Brenneman, D | 1 |
| Cree, BA | 1 |
| Sampat, M | 1 |
| Hauser, SL | 1 |
| Nelson, SJ | 1 |
| Pelletier, D | 1 |
| Guillen-Del Castillo, A | 1 |
| Alonso, J | 1 |
| Martínez-Valle, F | 1 |
| Alonso-Vila, S | 1 |
| Garrido-Castro, AC | 1 |
| Vilardell-Tarrés, M | 1 |
| Rovira, Á | 1 |
| Ordi-Ros, J | 1 |
| Yang, Y | 1 |
| Liu, Y | 1 |
| Zheng, L | 1 |
| Wu, T | 1 |
| Li, J | 1 |
| Zhang, Q | 1 |
| Li, X | 1 |
| Yuan, F | 1 |
| Wang, L | 1 |
| Guo, J | 1 |
| Almuqbel, M | 1 |
| Melzer, TR | 1 |
| Myall, DJ | 1 |
| MacAskill, MR | 1 |
| Pitcher, TL | 1 |
| Livingston, L | 1 |
| Wood, KL | 1 |
| Keenan, RJ | 1 |
| Dalrymple-Alford, JC | 1 |
| Anderson, TJ | 1 |
| Thambisetty, M | 1 |
| Hye, A | 1 |
| Foy, C | 1 |
| Daly, E | 1 |
| Glover, A | 1 |
| Cooper, A | 1 |
| Simmons, A | 1 |
| Murphy, D | 1 |
| Lovestone, S | 1 |
| Imamura, A | 1 |
| Miyajima, H | 1 |
| Ito, R | 1 |
| Orii, KO | 1 |
| Kawamori, R | 2 |
| Tajima, N | 2 |
| Iwamoto, Y | 2 |
| Kashiwagi, A | 2 |
| Shimamoto, K | 2 |
| Kaku, K | 2 |
| Pilatus, U | 1 |
| Lais, C | 1 |
| Rochmont, Adu M | 1 |
| Kratzsch, T | 1 |
| Frölich, L | 1 |
| Maurer, K | 1 |
| Zanella, FE | 1 |
| Lanfermann, H | 1 |
| Pantel, J | 1 |
| Mühlhauser, I | 1 |
| Shen, L | 1 |
| Sun, X | 1 |
| Yao, L | 1 |
| Davison, JE | 1 |
| Hendriksz, CJ | 1 |
| Sun, Y | 1 |
| Davies, NP | 1 |
| Gissen, P | 1 |
| Peet, AC | 1 |
| Haley, AP | 1 |
| Gonzales, MM | 1 |
| Tarumi, T | 1 |
| Miles, SC | 1 |
| Goudarzi, K | 1 |
| Tanaka, H | 1 |
| Walecki, J | 1 |
| Barcikowska, M | 1 |
| Ćwikła, JB | 1 |
| Gabryelewicz, T | 1 |
| Lim, TS | 1 |
| Hong, YH | 1 |
| Lee, HY | 1 |
| Choi, JY | 1 |
| Kim, HS | 1 |
| Moon, SY | 1 |
| Pascual-Castroviejo, I | 1 |
| Pascual-Pascual, SI | 1 |
| Velazquez-Fragua, R | 1 |
| Viaño, J | 1 |
| Podell, M | 1 |
| Hadjiconstantinou, M | 1 |
| Smith, MA | 1 |
| Neff, NH | 1 |
| Brockmann, K | 1 |
| Dechent, P | 1 |
| Meins, M | 1 |
| Haupt, M | 1 |
| Sperner, J | 1 |
| Stephani, U | 1 |
| Frahm, J | 3 |
| Hanefeld, F | 2 |
| Sener, RN | 1 |
| Estensen, RD | 1 |
| Jordan, MM | 1 |
| Wiedmann, TS | 1 |
| Galbraith, AR | 1 |
| Steele, VE | 1 |
| Wattenberg, LW | 1 |
| Fuller, RA | 1 |
| Westmoreland, SV | 1 |
| Ratai, E | 1 |
| Greco, JB | 1 |
| Kim, JP | 1 |
| Lentz, MR | 1 |
| He, J | 1 |
| Sehgal, PK | 1 |
| Masliah, E | 1 |
| Halpern, E | 1 |
| Lackner, AA | 1 |
| González, RG | 1 |
| Willemsen, MA | 1 |
| Van Der Graaf, M | 1 |
| Van Der Knaap, MS | 1 |
| Heerschap, A | 1 |
| Van Domburg, PH | 1 |
| Gabreëls, FJ | 1 |
| Rotteveel, JJ | 1 |
| Alkan, A | 1 |
| Kutlu, R | 1 |
| Sigirci, A | 1 |
| Aslan, M | 1 |
| Sarac, K | 1 |
| Yakinci, C | 1 |
| Katz-Brull, R | 1 |
| Lenkinski, RE | 1 |
| Du Pasquier, RA | 1 |
| Koralnik, IJ | 1 |
| Ashwal, S | 1 |
| Holshouser, B | 1 |
| Tong, K | 1 |
| Serna, T | 1 |
| Osterdock, R | 1 |
| Gross, M | 1 |
| Kido, D | 1 |
| Moser, HW | 1 |
| Barker, PB | 1 |
| Tkác, I | 1 |
| Charnas, LR | 1 |
| Choi, IY | 1 |
| Bjoraker, KJ | 1 |
| Shapiro, EG | 1 |
| Gruetter, R | 1 |
| Sastre-Garriga, J | 1 |
| Ingle, GT | 1 |
| Chard, DT | 1 |
| Ramió-Torrentà, L | 1 |
| McLean, MA | 1 |
| Miller, DH | 1 |
| Thompson, AJ | 1 |
| Wolf, NI | 1 |
| Harting, I | 1 |
| Boltshauser, E | 1 |
| Wiegand, G | 1 |
| Koch, MJ | 1 |
| Schmitt-Mechelke, T | 1 |
| Martin, E | 1 |
| Zschocke, J | 1 |
| Uhlenberg, B | 1 |
| Hoffmann, GF | 1 |
| Weber, L | 1 |
| Ebinger, F | 1 |
| Rating, D | 1 |
| Metastasio, A | 1 |
| Rinaldi, P | 1 |
| Tarducci, R | 1 |
| Mariani, E | 1 |
| Feliziani, FT | 1 |
| Cherubini, A | 1 |
| Pelliccioli, GP | 1 |
| Gobbi, G | 1 |
| Senin, U | 1 |
| Mecocci, P | 1 |
| Liao, Y | 1 |
| Takashima, S | 1 |
| Zhao, H | 1 |
| Asano, Y | 1 |
| Shintani, Y | 1 |
| Minamino, T | 1 |
| Kim, J | 2 |
| Fujita, M | 1 |
| Hori, M | 1 |
| Kitakaze, M | 2 |
| Kato, Z | 2 |
| Asano, T | 1 |
| Kondo, N | 2 |
| Czaplinski, A | 1 |
| Yen, AA | 1 |
| Simpson, EP | 1 |
| Appel, SH | 1 |
| Nakatani, S | 1 |
| Hashimura, K | 1 |
| Komamura, K | 1 |
| Kanzaki, H | 1 |
| Asakura, M | 1 |
| Asanuma, H | 1 |
| Kokubo, Y | 1 |
| Tomoike, H | 1 |
| Anlar, B | 1 |
| Broom, KA | 1 |
| Anthony, DC | 1 |
| Lowe, JP | 1 |
| Griffin, JL | 1 |
| Scott, H | 1 |
| Blamire, AM | 1 |
| Styles, P | 1 |
| Perry, VH | 1 |
| Sibson, NR | 1 |
| Pascual, JM | 1 |
| Solivera, J | 1 |
| Prieto, R | 1 |
| Barrios, L | 1 |
| López-Larrubia, P | 1 |
| Cerdán, S | 1 |
| Roda, JM | 1 |
| Wong, YC | 1 |
| Au, WL | 1 |
| Xu, M | 1 |
| Ye, J | 1 |
| Lim, CC | 1 |
| Alimenti, A | 1 |
| Delavelle, J | 1 |
| Lazeyras, F | 1 |
| Yilmaz, H | 1 |
| Dietrich, PY | 1 |
| de Tribolet, N | 1 |
| Lövblad, KO | 1 |
| Xu, YH | 1 |
| Reboulet, R | 1 |
| Quinn, B | 1 |
| Huelsken, J | 1 |
| Witte, D | 1 |
| Grabowski, GA | 1 |
| Kawashima, S | 1 |
| Kaneto, H | 1 |
| Sakamoto, K | 1 |
| Yasuda, T | 1 |
| Kuroda, A | 1 |
| Shiraiwa, T | 1 |
| Yamamoto, K | 1 |
| Kasami, R | 1 |
| Matsuoka, TA | 1 |
| Yamasaki, Y | 1 |
| Matsuhisa, M | 1 |
| Falini, A | 1 |
| Calabrese, G | 1 |
| Filippi, M | 1 |
| Origgi, D | 1 |
| Lipari, S | 1 |
| Colombo, B | 1 |
| Comi, G | 1 |
| Scotti, G | 1 |
| Kruse, B | 1 |
| Pouwels, PJ | 2 |
| Christen, HJ | 1 |
| Hanefeld, FA | 1 |
| Wilichowski, E | 1 |
| Jack, CR | 1 |
| Xu, YC | 1 |
| Campeau, NG | 1 |
| O'Brien, PC | 1 |
| Smith, GE | 1 |
| Ivnik, RJ | 1 |
| Boeve, BF | 1 |
| Kokmen, E | 1 |
| Tangalos, EG | 1 |
| Petersen, RC | 1 |
| Mizuno, S | 1 |
| Takahashi, Y | 1 |
| Goto, H | 1 |
| Hoshi, H | 1 |
| Oki, Y | 1 |
| Okubo, M | 1 |
| Tanaka, S | 1 |
| Nakanishi, K | 1 |
| Kobayashi, T | 1 |
| Murase, T | 1 |
| Malloy, CR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open Label Study for the Use of Tyrosine Kinase Inhibitors for Treatment of Cognitive Decline Due to Degenerative Dementias[NCT02921477] | Phase 1 | 150 participants (Anticipated) | Interventional | 2016-09-30 | Enrolling by invitation | ||
| Focused Ultrasound Delivery of Exosomes for Treatment of Refractory Depression, Anxiety, and Neurodegenerative Dementias[NCT04202770] | 300 participants (Anticipated) | Interventional | 2019-12-01 | Suspended (stopped due to Pending COVID-19 pandemic; pending status of product development) | |||
| Sjogren-Larsson Syndrome: A Longitudinal Study of Natural History, Clinical Variation and Evaluation of Biochemical Markers[NCT01971957] | 20 participants (Actual) | Observational [Patient Registry] | 2013-04-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for inositol and Disease Exacerbation
| Article | Year |
|---|---|
Proton MRS in mild cognitive impairment.
Topics: Alzheimer Disease; Animals; Aspartic Acid; Biomarkers; Brain; Choline; Cognitive Dysfunction; Creati | 2013 |
[Corpus callosum tumor as the presenting symptom of neurofibromatosis type 1 in a patient and literature review].
Topics: Brain Neoplasms; Brain Stem Neoplasms; Cerebellar Neoplasms; Child, Preschool; Choline; Corpus Callo | 2012 |
4 trials available for inositol and Disease Exacerbation
| Article | Year |
|---|---|
Myo-inositol and selenium reduce the risk of developing overt hypothyroidism in patients with autoimmune thyroiditis.
Topics: Autoantibodies; Chemokine CXCL10; Disease Progression; Drug Therapy, Combination; Female; Humans; Hy | 2017 |
Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance.
Topics: Administration, Oral; Analysis of Variance; Diabetes Mellitus, Type 2; Disease Progression; Double-B | 2009 |
[Alpha-glucosidase inhibitor for the prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese subjects with impaired glucose tolerance].
Topics: Asian People; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Disease Progression; Enzyme Inhibi | 2009 |
Metabolite changes in normal-appearing gray and white matter are linked with disability in early primary progressive multiple sclerosis.
Topics: Adult; Age of Onset; Aged; Aspartic Acid; Biomarkers; Case-Control Studies; Cerebral Cortex; Choline | 2005 |
61 other studies available for inositol and Disease Exacerbation
| Article | Year |
|---|---|
Change in Urinary Myoinositol/Citrate Ratio Associates with Progressive Loss of Renal Function in ADPKD Patients.
Topics: Citric Acid; Disease Progression; Female; Glomerular Filtration Rate; Humans; Inositol; Kidney; Male | 2022 |
Spatio-temporal metabolic rewiring in the brain of TgF344-AD rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Choline; Creatine; Disease Models, Animal; Disease Progression; G | 2022 |
Short echo-time Magnetic Resonance Spectroscopy in ALS, simultaneous quantification of glutamate and GABA at 3 T.
Topics: Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Atrophy; Choline; Creatine; Disease Progression; | 2019 |
Role of selenium and myo-inositol supplementation on autoimmune thyroiditis progression.
Topics: Adult; Autoantibodies; Disease Progression; Drug Therapy, Combination; Female; Hashimoto Disease; Hu | 2020 |
Role of inositol to improve surfactant functions and reduce IL-6 levels: A potential adjuvant strategy for SARS-CoV-2 pneumonia?
Topics: COVID-19; Cytokines; Disease Progression; Humans; Inflammation; Inositol; Interleukin-6; Lung; Phosp | 2020 |
Probiotics improve the neurometabolic profile of rats with chronic cholestatic liver disease.
Topics: Ammonium Compounds; Animals; Behavior, Animal; Bifidobacterium; Bile Ducts; Bilirubin; Blood Glucose | 2021 |
Time-based investigation of urinary metabolic markers for Type 2 diabetes: Metabolomics approach for diabetes management.
Topics: Animals; Biomarkers; Carnitine; Cluster Analysis; Deoxyglucose; Diabetes Mellitus, Experimental; Dis | 2021 |
Proton MR spectroscopy of lesion evolution in multiple sclerosis: Steady-state metabolism and its relationship to conventional imaging.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Cross-Sectional Studies; Disease Progression; Female | 2017 |
Decreased N-Acetyl Aspartate/Myo-Inositol Ratio in the Posterior Cingulate Cortex Shown by Magnetic Resonance Spectroscopy May Be One of the Risk Markers of Preclinical Alzheimer's Disease: A 7-Year Follow-Up Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Biomarkers; Cognitive Dysfunction; Diseas | 2017 |
Neurochemical abnormalities in premanifest and early spinocerebellar ataxias.
Topics: Activities of Daily Living; Adult; Aged; Aspartic Acid; Ataxins; Brain; Brain Diseases, Metabolic; C | 2018 |
Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification.
Topics: Animals; Calcinosis; Cardiovascular Diseases; Cholecalciferol; Disease Models, Animal; Disease Progr | 2018 |
Motor cortex metabolite alterations in amyotrophic lateral sclerosis assessed in vivo using edited and non-edited magnetic resonance spectroscopy.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Disease Progression; Female; Glutathione; Humans; Image | 2019 |
Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartic Acid; | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance imaging spectroscopy in pediatric atypical teratoid rhabdoid tumors of the brain.
Topics: Brain; Brain Neoplasms; Child, Preschool; Choline; Chromosomal Proteins, Non-Histone; Creatine; Diag | 2014 |
Clinical predictors of atheroma progression despite optimal glycemic control in early-stage diabetic patients with coronary artery disease: Insight from the DIANA study.
Topics: Blood Glucose; Coronary Angiography; Coronary Artery Disease; Cyclohexanes; Diabetes Mellitus; Disea | 2014 |
Hippocampal neurochemical changes in senescent mice induced with chronic injection of D-galactose and NaNO₂: an in vitro high-resolution NMR spectroscopy study at 9.4T.
Topics: Amyloid; Animals; Apoptosis; Aspartic Acid; Behavior, Animal; Cell Proliferation; Congo Red; Disease | 2014 |
Magnetic resonance spectroscopy markers of disease progression in multiple sclerosis.
Topics: Adult; Aspartic Acid; Atrophy; Biomarkers; Case-Control Studies; Disability Evaluation; Disease Prog | 2014 |
Increased myo-inositol in parietal white and gray matter as a biomarker of poor prognosis in neuropsychiatric lupus: a case report.
Topics: Atrophy; Biomarkers; Cognition; Disease Progression; Female; Gray Matter; Humans; Immunosuppressive | 2014 |
Serum metabonomic analysis of apoE(-/-) mice reveals progression axes for atherosclerosis based on NMR spectroscopy.
Topics: Animals; Atherosclerosis; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Choline; Diet, High-Fat; D | 2014 |
Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson's disease in a clinical setting.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Bayes Theorem; Case-Control Studies; Choline; Cognitive Dysf | 2016 |
Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease.
Topics: Aged; alpha-Macroglobulins; Alzheimer Disease; Aspartic Acid; Biomarkers; Complement Factor H; Disea | 2008 |
Serial MR imaging and 1H-MR spectroscopy in monozygotic twins with Tay-Sachs disease.
Topics: Aspartic Acid; Basal Ganglia; Brain; Cerebral Cortex; Child, Preschool; Choline; Corpus Callosum; Cr | 2008 |
Conversion to dementia in mild cognitive impairment is associated with decline of N-actylaspartate and creatine as revealed by magnetic resonance spectroscopy.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Choline; Cognition; Cognition Disorders; Creatine; De | 2009 |
Voglibose for prevention of type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Disease Progression; Humans; Hypoglycemic Agents; Inositol | 2009 |
Voglibose for prevention of type 2 diabetes mellitus.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Disease Progression; Glycated Hemoglobin; Humans; Hypoglyc | 2009 |
Quantitative in vivo brain magnetic resonance spectroscopic monitoring of neurological involvement in mucopolysaccharidosis type II (Hunter Syndrome).
Topics: Adolescent; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Case-Control Studies; Child; Child, Pre | 2010 |
Elevated cerebral glutamate and myo-inositol levels in cognitively normal middle-aged adults with metabolic syndrome.
Topics: Adult; Brain Chemistry; Cognition Disorders; Disease Progression; Female; Glutamic Acid; Humans; Ino | 2010 |
N-acetylaspartate, choline, myoinositol, glutamine and glutamate (glx) concentration changes in proton MR spectroscopy (1H MRS) in patients with mild cognitive impairment (MCI).
Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Disease Progression; Female; | 2011 |
Metabolite investigation in both anterior and posterior cingulate gyri in Alzheimer's disease spectrum using 3-tesla MR spectroscopy.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Cognition Disorders; Creatine; Disease Pr | 2012 |
Proton magnetic resonance imaging and spectroscopy identify metabolic changes in the striatum in the MPTP feline model of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aspartic Acid; Brain; Cats; Choline; Corpus S | 2003 |
Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease.
Topics: Alexander Disease; Aspartic Acid; Brain; Child; Child, Preschool; Demyelinating Diseases; Disease Pr | 2003 |
Pantothenate kinase-associated neurodegeneration: MR imaging, proton MR spectroscopy, and diffusion MR imaging findings.
Topics: Adolescent; Aspartic Acid; Brain; Cerebellar Nuclei; Choline; Creatine; Diagnosis, Differential; Dif | 2003 |
Effect of chemopreventive agents on separate stages of progression of benzo[alpha]pyrene induced lung tumors in A/J mice.
Topics: Adenoma; Aerosols; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Budesonide; Carcinogens; Disea | 2004 |
A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV/macaque model of neuroAIDS.
Topics: Acute Disease; AIDS Dementia Complex; Animals; Aspartic Acid; Brain; Choline; Chronic Disease; Creat | 2004 |
MR imaging and proton MR spectroscopic studies in Sjögren-Larsson syndrome: characterization of the leukoencephalopathy.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Cerebral Ventricles; Child; Child, Preschool; Choline; Crea | 2004 |
Subacute sclerosing panencephalitis with fulminating course: follow-up magnetic resonance spectroscopy (MRS) findings.
Topics: Aspartic Acid; Brain; Cerebral Cortex; Child, Preschool; Choline; Creatine; Diagnosis, Differential; | 2004 |
Elevation of myoinositol is associated with disease containment in progressive multifocal leukoencephalopathy.
Topics: Adult; Aspartic Acid; Cerebellum; Cerebral Cortex; Choline; Creatine; Disease Progression; Female; H | 2004 |
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Com | 2004 |
Magnetic resonance spectroscopy: a new guide for the therapy of adrenoleukodystrophy.
Topics: Adolescent; Adrenoleukodystrophy; Brain Chemistry; Child; Child, Preschool; Disease Progression; Hem | 2005 |
Assessment of adrenoleukodystrophy lesions by high field MRS in non-sedated pediatric patients.
Topics: Adolescent; Adrenoleukodystrophy; Aspartic Acid; Brain Chemistry; Child; Child, Preschool; Creatine; | 2005 |
Leukoencephalopathy with ataxia, hypodontia, and hypomyelination.
Topics: Age of Onset; Anodontia; Ataxia; Atrophy; Basal Ganglia; Body Height; Brain; Cerebellum; Child; Chil | 2005 |
Conversion of MCI to dementia: Role of proton magnetic resonance spectroscopy.
Topics: Aged; Amnesia; Aspartic Acid; Cerebral Cortex; Choline; Cognition Disorders; Creatine; Dementia; Dis | 2006 |
Control of plasma glucose with alpha-glucosidase inhibitor attenuates oxidative stress and slows the progression of heart failure in mice.
Topics: Acetophenones; Animals; Blotting, Western; Body Weight; Cells, Cultured; Disease Progression; Echoca | 2006 |
Inosiplex affects the spectra of proton magnetic resonance spectroscopy in subacute sclerosing panencephalitis.
Topics: Adolescent; Antiviral Agents; Artifacts; Aspartic Acid; Choline; Disease Progression; Dominance, Cer | 2006 |
Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing?
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Dipeptides; Disease Progression; Female; Hum | 2006 |
Abnormal glucose tolerance contributes to the progression of chronic heart failure in patients with dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Chronic Disease; Disease Progression; Echocardiography; Female; Glucose Int | 2006 |
Quantification of neurometabolites in subacute sclerosing panencephalitis by 1H-MRS.
Topics: Aspartic Acid; Brain Chemistry; Confounding Factors, Epidemiologic; Disease Progression; Humans; Ino | 2007 |
MRI and MRS alterations in the preclinical phase of murine prion disease: association with neuropathological and behavioural changes.
Topics: Animals; Aspartic Acid; Astrocytes; Body Water; Brain; Choline; Creatine; Diffusion; Disease Models, | 2007 |
Time course of early metabolic changes following diffuse traumatic brain injury in rats as detected by (1)H NMR spectroscopy.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Injuries; Creatine; Diffuse Axona | 2007 |
Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients.
Topics: Adult; Ammonia; Biomarkers; Brain; Brain Mapping; Cerebral Cortex; Choline; Citrulline; Citrullinemi | 2007 |
Monovoxel 1H magnetic resonance spectroscopy in the progression of gliomas.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Disease Progression; Female; Glioma; | 2007 |
Dependence of reversibility and progression of mouse neuronopathic Gaucher disease on acid beta-glucosidase residual activity levels.
Topics: Animals; Central Nervous System; Cytokines; Disease Models, Animal; Disease Progression; Female; Gau | 2008 |
Acute progression of severe insulin edema accompanied by pericardial and pleural effusion in a patient with type 2 diabetes.
Topics: Administration, Oral; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Progression; Ede | 2008 |
Benign versus secondary-progressive multiple sclerosis: the potential role of proton MR spectroscopy in defining the nature of disability.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Disease Progression; Female; Follow-Up Studies; Huma | 1998 |
Proton magnetic resonance spectroscopy of linear nevus sebaceus syndrome.
Topics: Aspartic Acid; Brain Chemistry; Cerebral Cortex; Child, Preschool; Choline; Creatine; Disease Progre | 1998 |
Quantitative proton magnetic resonance spectroscopy of cerebral metabolic disturbances in patients with MELAS.
Topics: Adolescent; Adult; Brain; Child; Disease Progression; Female; Humans; Inositol; Magnetic Resonance S | 1999 |
Regional metabolic patterns in mild cognitive impairment and Alzheimer's disease: A 1H MRS study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain Mapping; Choline; Cognition Disorde | 2000 |
Magnetic resonance spectroscopy of tubers in patients with tuberous sclerosis.
Topics: Adult; Age Factors; Aspartic Acid; Case-Control Studies; Child; Child, Preschool; Creatine; Disease | 2000 |
Diabetes mellitus secondary to glycogen storage disease type III.
Topics: Age of Onset; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Disease Progression; Enzyme Inhib | 2000 |
Correlation of cerebral metabolites with clinical outcome among patients with severe congestive heart failure.
Topics: Aspartic Acid; Brain; Choline; Cognition Disorders; Creatine; Disease Progression; Heart Failure; Hu | 2001 |