Page last updated: 2024-10-19

inositol and Diabetes Mellitus

inositol has been researched along with Diabetes Mellitus in 97 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
" Myoinositol can be measured in urine and has been found to be elevated in patients with diabetes and glucose intolerance; it has thus proven useful as a marker for the early detection of these conditions."7.74Lucica MI urinary myoinositol kit: a new diagnostic test for diabetes mellitus and glucose intolerance. ( Kawazu, S; Yamakoshi, M, 2008)
"To assess the therapeutic effect of losartan on type 2 diabetes mellitus (DM2) with gas chromatography (GC)-based metabonomics."7.74[Assessment of therapeutic effect of losartan on diabetes mellitus with gas chromatography-based metabonomics]. ( Gao, P; Lu, X; Shi, XZ; Xu, GW; Yuan, KL, 2007)
"A series of in vivo and in vitro investigations was performed to examine the localisation of sorbitol pathway activity in the rat renal cortex and to investigate the possible relation that the acculumation of sorbitol pathway intermediates in renal cortical tissue may have to the pathogenesis of renal complications in diabetes mellitus."7.65The localisation of sorbitol pathway activity in the rat renal cortex and its relationship to the pathogenesis of the renal complications of diabetes mellitus. ( Hollows, FC; Hutton, JC; Schofield, PJ; Williams, JF, 1975)
"The metabolism of myoinositol has been studied in 10 nondiabetic subjects and in six patients with diabetes mellitus before and after insulin therapy."7.65Myoinositol metabolism in diabetes mellitus. Effect of insulin treatment. ( Clements, RS; Reynertson, R, 1977)
"Serum and urinary myo-inositol and urinary glucose were estimated by means of gas-liquid chromatography in 54 patients with glomerulonephritis with and without renal failure."7.65Changes in serum and urinary myo-inositol levels in chronic glomerulonephritis. ( Pitkänen, E, 1976)
" We conclude that plasma levels of both pinitol and D-chiro-inositol are very responsive to pinitol ingestion, but insulin sensitivity does not increase after pinitol treatment in individuals with obesity and mild type 2 diabetes."5.09Effect of pinitol treatment on insulin action in subjects with insulin resistance. ( Christiansen, M; Davis, A; Hellerstein, MK; Horowitz, JF; Klein, S; Ostlund, RE, 2000)
" Myoinositol can be measured in urine and has been found to be elevated in patients with diabetes and glucose intolerance; it has thus proven useful as a marker for the early detection of these conditions."3.74Lucica MI urinary myoinositol kit: a new diagnostic test for diabetes mellitus and glucose intolerance. ( Kawazu, S; Yamakoshi, M, 2008)
"To assess the therapeutic effect of losartan on type 2 diabetes mellitus (DM2) with gas chromatography (GC)-based metabonomics."3.74[Assessment of therapeutic effect of losartan on diabetes mellitus with gas chromatography-based metabonomics]. ( Gao, P; Lu, X; Shi, XZ; Xu, GW; Yuan, KL, 2007)
" The patient started prednisone treatment, but one month later treatment with voglibose, an alpha-glucosidase inhibitor (alpha-GI), was started because of prednisone-induced diabetes mellitus."3.73Pneumatosis cystoides intestinalis after alpha-glucosidase inhibitor treatment in a patient with interstitial pneumonitis. ( Haruta, Y; Hisamoto, A; Matsuo, K; Mizushima, T; Sato, K; Tanimoto, M; Tanimoto, Y, 2006)
"A series of in vivo and in vitro investigations was performed to examine the localisation of sorbitol pathway activity in the rat renal cortex and to investigate the possible relation that the acculumation of sorbitol pathway intermediates in renal cortical tissue may have to the pathogenesis of renal complications in diabetes mellitus."3.65The localisation of sorbitol pathway activity in the rat renal cortex and its relationship to the pathogenesis of the renal complications of diabetes mellitus. ( Hollows, FC; Hutton, JC; Schofield, PJ; Williams, JF, 1975)
"Serum and urinary myo-inositol and urinary glucose were estimated by means of gas-liquid chromatography in 54 patients with glomerulonephritis with and without renal failure."3.65Changes in serum and urinary myo-inositol levels in chronic glomerulonephritis. ( Pitkänen, E, 1976)
"Sorbinil was detected in both lens and aqueous."2.66The penetration of Sorbinil, an aldose reductase inhibitor, into lens, aqueous humour and erythrocytes of patients undergoing cataract extraction. ( Burgess, SE; Cheng, H; Crabbe, MJ; Petchey, M, 1985)
"Postprandial hyperglycemia is frequently associated with visceral obesity which plays a key role in metabolic abnormalities such as dyslipidemia and hypertension."2.42[Pharmacological treatment of postprandial hyperglycemia in hypertensive patients with type 2 diabetes mellitus]. ( Yamada, K, 2003)
"The severe intestinal lipodystrophy that develops in female gerbils consuming inositol-deficient diets is likely mediated by a reduced synthesis of PI and the associated impairment of chylomicron assembly and secretion."2.37Metabolism and function of myo-inositol and inositol phospholipids. ( Holub, BJ, 1986)
"Mononeuritis (or mononeuritis multiplex) seems to be the result of ischaemia due to intrinsic or extrinsic (altered coagulability) vascular disease."2.37[Pathogenesis of diabetic neuropathies]. ( Arlot, S; Lalau, JD; Quichaud, J, 1985)
"Myo-inositol treatment resulted in positive modulation of PINK1/Parkin pathway as well as PHB2 and NIX."1.72Renoprotective potential of myo-inositol on diabetic kidney disease: Focus on the role of the PINK1/Parkin pathway and mitophagy receptors. ( Arruri, VK; Kalvala, AK; Khatri, DK; Sherkhane, B; Singh, SB, 2022)
"Factors associated with disease progression despite optimal glucose control remain to be elucidated."1.40Clinical predictors of atheroma progression despite optimal glycemic control in early-stage diabetic patients with coronary artery disease: Insight from the DIANA study. ( Kataoka, Y; Kimura, K; Kosuge, M; Miyamoto, Y; Miyazaki, S; Sase, K; Yasuda, S; Yoshimasa, Y, 2014)
"Myo-inositol (MI) is a stereoisomer of inositol and serves as a precursor of inositol phospholipids."1.37Evaluation of serum and urine 1,5-anhydro-D-glucitol and myo-inositol concentrations in healthy dogs. ( Arai, T; Hayakawa, N; Ishioka, K; Miki, Y; Mori, A; Niki, T; Oda, H; Saeki, K; Sako, T; Sato, T; Tazaki, H, 2011)
"Diabetes mellitus is associated with a significant reduction in the serum concentration of Mg2+."1.28Effect of Mg2+ on Na(+)-dependent inositol transport. Role for Mg2+ in etiology of diabetic complications. ( Baxter, MA; Brown, G; Bunce, CM; Grafton, G; Sheppard, MC, 1992)

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-199059 (60.82)18.7374
1990's14 (14.43)18.2507
2000's11 (11.34)29.6817
2010's7 (7.22)24.3611
2020's6 (6.19)2.80

Authors

AuthorsStudies
Sherkhane, B1
Kalvala, AK1
Arruri, VK1
Khatri, DK1
Singh, SB1
Chen, J1
Guo, P1
Liu, X2
Liao, H1
Chen, K1
Wang, Y1
Qin, J1
Yang, F1
Koyama, T1
Omoruyi, FO1
Stennett, D1
Foster, S1
Dilworth, L1
Alssema, M1
Ruijgrok, C1
Blaak, EE1
Egli, L1
Dussort, P1
Vinoy, S1
Dekker, JM1
Denise Robertson, M1
Kaur, N1
Kumar, V1
Nayak, SK1
Wadhwa, P1
Kaur, P1
Sahu, SK1
Maki, N1
Nishie, W1
Takazawa, M1
Kakurai, M1
Yamada, T1
Umemoto, N1
Kawase, M1
Izumi, K1
Shimizu, H1
Demitsu, T1
Ortiz-Flores, AE1
Luque-Ramírez, M1
Escobar-Morreale, HF1
Kataoka, Y2
Yasuda, S2
Miyamoto, Y2
Sase, K2
Kosuge, M2
Kimura, K2
Yoshimasa, Y2
Miyazaki, S2
Adams, GG1
Imran, S1
Wang, S1
Mohammad, A1
Kok, MS1
Gray, DA1
Channell, GA1
Harding, SE1
Yamakoshi, M1
Kawazu, S1
Yuan, KL1
Shi, XZ1
Lu, X1
Gao, P1
Xu, GW1
Tsujimoto, T1
Shioyama, E1
Moriya, K1
Kawaratani, H1
Shirai, Y1
Toyohara, M1
Mitoro, A1
Yamao, J1
Fujii, H1
Fukui, H1
Hirasawa, Y1
Matsui, Y1
Ohtsu, S1
Yamane, K1
Toyoshi, T1
Kyuki, K1
Sakai, T1
Feng, Y1
Nagamatsu, T1
Miki, Y1
Mori, A1
Hayakawa, N1
Niki, T1
Oda, H1
Saeki, K1
Sato, T1
Tazaki, H1
Ishioka, K1
Arai, T1
Sako, T1
Shimabukuro, M1
Masuzaki, H1
Sata, M1
Yamada, K1
DAUGHADAY, WH1
LARNER, J1
GONZALEZ ALVAREZ, J2
PERLES, R3
COLAS, MC3
PIRIE, A2
VANHEYNINGEN, R1
Kawamori, R1
Kadowaki, T1
Ishida, H1
FELCH, WC1
DOTTI, LB1
Yamanouchi, T1
Hisamoto, A1
Mizushima, T1
Sato, K1
Haruta, Y1
Tanimoto, Y1
Tanimoto, M1
Matsuo, K1
Maruta, T1
Komai, K1
Takamori, M1
Yamada, M1
Greene, DA5
Yagihashi, S1
Lattimer, SA3
Sima, AA2
Tomlinson, DR2
Mayer, JH1
Gulak, PV1
Varma, SD3
Richards, RD2
Sherman, WR3
Dyck, PJ2
Tarui, S1
Mayhew, JA1
Gillon, KR2
Hawthorne, JN3
Gregersen, G2
Bertelsen, B1
Harbo, H1
Larsen, E1
Andersen, JR1
Helles, A1
Schmiegelow, M1
Christensen, JE1
Servo, C4
Ostlund, RE3
Stevens, MJ1
Feldman, EL1
Killen, PD1
Henry, DN1
Thomas, T1
Dananberg, J1
McGill, JB1
Herskowitz, I1
Kipnis, DM1
Santiago, JV1
Niwa, T1
Dewald, L1
Sone, J1
Miyazaki, T1
Kajita, M1
Belpoliti, M1
Maraini, G1
Nakashima, S1
Nozawa, Y2
Kudo, S2
Hara, T1
Hotta, N3
Nakamura, J1
Kinne, RK1
Mooradian, AD1
Thurman, JE1
Davis, A1
Christiansen, M1
Horowitz, JF1
Klein, S1
Hellerstein, MK1
Luo, H1
Imoto, T1
Hiji, Y1
Salway, JG1
Whitehead, L1
Finnegan, JA1
Karunanayaka, A1
Barnett, D1
Payne, RB1
Schocket, SS1
De Jesus, PV1
Winegrad, AI1
Hutton, JC3
Schofield, PJ2
Williams, JF3
Hollows, FC3
Schofield, PH1
Regtop, HL1
Anderson, JW1
Daumerie-Goffinet, C1
Lambert, AE1
Clements, RS2
Trznadel, K2
Lutz, W2
Reynertson, R1
Palo, J1
Pitkänen, E4
Walasek, L1
Pfaffenberger, CD1
Szafranek, J1
Horning, EC1
Renold, AE1
Heaf, DJ1
Galton, DJ1
Radhakrishnamurthy, B1
Berenson, GS1
Pargaonkar, PS1
Voors, AW1
Srinivasan, SR1
Plavidal, F1
Dolan, P1
Dalferes, ER1
Kreis, R1
Ross, BD1
Grafton, G1
Bunce, CM1
Sheppard, MC1
Brown, G1
Baxter, MA1
Sakamoto, N1
Moller, DE1
Moses, AC1
Holub, BJ1
Hatano, M1
Uno, K1
Fuda, H1
Sugiura, M1
Harada, K1
Kawano, Y1
Maruyama, S1
Airey, CM1
Price, DE1
Kemp, JV1
Perkins, CM2
Wales, JK1
Hattori, H1
Okano, Y1
Balabolkin, MI1
Islambekov, RR1
Arendrup, K1
Hawley, J1
Troyer, DA1
Schwertz, DW1
Kreisberg, JI1
Venkatachalam, MA1
Zimmerman, BR1
Vilen, TH1
Minnerath, SR1
Karnes, JL1
Yao, JK1
Poduslo, JF1
Whiteley, SJ1
Hasegawa, M1
Doi, K1
Baba, S1
Hale, PJ1
Nattrass, M1
Silverman, SH1
Sennit, C1
Uden, A1
Sundkvist, G1
Lalau, JD1
Arlot, S1
Quichaud, J1
Crabbe, MJ1
Petchey, M1
Burgess, SE1
Cheng, H1
Macfarlane, CM1
Aloia, JF2
Nilakantan, S1
Kinoshita, JH1
Niedermeier, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Targeted Proteomic Analysis in the Plasma of Children With Diabetes Type 1 and Its Association With Peripheral Diabetic Neuropathy[NCT04257877]50 participants (Anticipated)Observational2018-11-20Recruiting
Inhibition of Intestinal Glucose Absorption by the Bioflavonoid Quercetin in the Obese and in Obese Type 2 Diabetics[NCT00065676]Phase 224 participants (Actual)Interventional2010-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

25 reviews available for inositol and Diabetes Mellitus

ArticleYear
New Frontiers for the Use of IP6 and Inositol Combination in Treating Diabetes Mellitus: A Review.
    Molecules (Basel, Switzerland), 2020, Apr-10, Volume: 25, Issue:7

    Topics: Animals; Biomarkers; Blood Cell Count; Carbohydrate Metabolism; Diabetes Mellitus; Dietary Supplemen

2020
Effects of alpha-glucosidase-inhibiting drugs on acute postprandial glucose and insulin responses: a systematic review and meta-analysis.
    Nutrition & diabetes, 2021, 03-03, Volume: 11, Issue:1

    Topics: 1-Deoxynojirimycin; Acarbose; Diabetes Mellitus; Glucose; Glycoside Hydrolase Inhibitors; Humans; In

2021
Alpha-amylase as molecular target for treatment of diabetes mellitus: A comprehensive review.
    Chemical biology & drug design, 2021, Volume: 98, Issue:4

    Topics: 1-Deoxynojirimycin; Acarbose; alpha-Amylases; Benzofurans; Blood Glucose; Diabetes Mellitus; Drug Di

2021
Pharmacotherapeutic management of comorbid polycystic ovary syndrome and diabetes.
    Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:17

    Topics: Animals; Diabetes Mellitus; Female; Glucose Intolerance; Humans; Inositol; Insulin; Insulin Resistan

2018
The hypoglycemic effect of pumpkin seeds, Trigonelline (TRG), Nicotinic acid (NA), and D-Chiro-inositol (DCI) in controlling glycemic levels in diabetes mellitus.
    Critical reviews in food science and nutrition, 2014, Volume: 54, Issue:10

    Topics: Alkaloids; Animals; Blood Glucose; Cucurbita; Diabetes Mellitus; Humans; Hypoglycemic Agents; Inosit

2014
Pneumatosis cystoides intestinalis following alpha-glucosidase inhibitor treatment: a case report and review of the literature.
    World journal of gastroenterology, 2008, Oct-21, Volume: 14, Issue:39

    Topics: Aged; Diabetes Mellitus; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Inositol; Male

2008
[Pharmacological treatment of postprandial hyperglycemia in hypertensive patients with type 2 diabetes mellitus].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61, Issue:7

    Topics: Acarbose; Cyclohexanes; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Enzyme

2003
Defects of axonal transport in diabetes mellitus--a possible contribution to the aetiology of diabetic neuropathy.
    Journal of autonomic pharmacology, 1984, Volume: 4, Issue:1

    Topics: Animals; Axonal Transport; Body Temperature; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dia

1984
[Physiological aspects of phosphoinositide metabolism].
    Uspekhi sovremennoi biologii, 1981, Volume: 91, Issue:2

    Topics: Animals; Calcium; Cell Membrane Permeability; Cyclization; Diabetes Mellitus; Diabetes Mellitus, Exp

1981
[Metabolic alterations and diabetic complications (author's transl)].
    Horumon to rinsho. Clinical endocrinology, 1980, Volume: 28, Issue:2

    Topics: Biological Transport, Active; Blood Glucose; Diabetes Mellitus; Diabetic Ketoacidosis; Hemoglobins;

1980
Aldose reductase inhibitors: an approach to the treatment of diabetic nerve damage.
    Diabetes/metabolism reviews, 1993, Volume: 9, Issue:3

    Topics: Aldehyde Reductase; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Neuropathi

1993
[Inositol].
    Nihon rinsho. Japanese journal of clinical medicine, 1995, Volume: 53 Su Pt 1

    Topics: Diabetes Mellitus; Humans; Inositol; Methods; Renal Insufficiency

1995
[Voglibose].
    Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55 Suppl

    Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus; Diet, Diabetic; Dietary Carbohydrates; Glyco

1997
[Myo-inositol].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56 Suppl 3

    Topics: Diabetes Mellitus; Diabetic Neuropathies; Gas Chromatography-Mass Spectrometry; Humans; Inositol

1998
Mechanisms of osmolyte release.
    Contributions to nephrology, 1998, Volume: 123

    Topics: Animals; Betaine; Calcium Signaling; Cell Membrane Permeability; Cell Polarity; Diabetes Mellitus; G

1998
Drug therapy of postprandial hyperglycaemia.
    Drugs, 1999, Volume: 57, Issue:1

    Topics: 1-Deoxynojirimycin; Acarbose; Amyloid; Carbamates; Diabetes Mellitus; Enzyme Inhibitors; Glucosamine

1999
Metabolic abnormalities contributing to diabetic complications. II. Peripheral nerves.
    The American journal of clinical nutrition, 1976, Volume: 29, Issue:4

    Topics: Animals; Axons; Cricetinae; Diabetes Mellitus; Diabetic Neuropathies; Disease Models, Animal; Glucos

1976
[Diabetic microangiopathies].
    Acta clinica Belgica, 1978, Volume: 33, Issue:4

    Topics: Basement Membrane; Blood Viscosity; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies

1978
Biochemical derangements in diabetes mellitus.
    Advances in experimental medicine and biology, 1979, Volume: 124

    Topics: Aorta; Basement Membrane; Blood Platelets; Blood Proteins; Carbohydrate Metabolism; Diabetes Mellitu

1979
[Biochemical and clinical aspects of myoinositol].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1976, Oct-25, Volume: 31, Issue:43

    Topics: Animals; Biological Transport, Active; Cell Membrane; Diabetes Mellitus; Fatty Liver; Guinea Pigs; H

1976
Metabolism and function of myo-inositol and inositol phospholipids.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport, Active; Carrier Prot

1986
Acute and chronic complications of diabetes mellitus in older patients.
    The American journal of medicine, 1986, May-16, Volume: 80, Issue:5A

    Topics: Adult; Aged; Aging; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Diabetic Coma; Diabet

1986
Inositol phospholipid metabolism in the kidney.
    Annual review of physiology, 1986, Volume: 48

    Topics: Adenosine Triphosphatases; Aminoglycosides; Animals; Anti-Bacterial Agents; Biological Transport; Ca

1986
Biochemical alterations and complications in diabetes.
    Clinical chemistry, 1986, Volume: 32, Issue:10 Suppl

    Topics: Biological Transport; Diabetes Complications; Diabetes Mellitus; Energy Metabolism; Glucose; Humans;

1986
[Pathogenesis of diabetic neuropathies].
    Annales de medecine interne, 1985, Volume: 136, Issue:6

    Topics: Animals; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Neuropathies; Energy Metabolism; Humans;

1985

Trials

8 trials available for inositol and Diabetes Mellitus

ArticleYear
Effects of voglibose and nateglinide on glycemic status and coronary atherosclerosis in early-stage diabetic patients.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:3

    Topics: Aged; Coronary Artery Disease; Cyclohexanes; Diabetes Complications; Diabetes Mellitus; Female; Glyc

2012
Voglibose inhibits postprandial hypotension in neurologic disorders and elderly people.
    Neurology, 2006, May-09, Volume: 66, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Autonomic Nervous System Diseases; Blood Glucose; Diabetes Mellitus;

2006
Oral supplementation of myoinositol: effects on peripheral nerve function in human diabetics and on the concentration in plasma, erythrocytes, urine and muscle tissue in human diabetics and normals.
    Acta neurologica Scandinavica, 1983, Volume: 67, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Diabetes Mellitus; Erythrocytes; Humans; Inositol; Muscles;

1983
Effect of pinitol treatment on insulin action in subjects with insulin resistance.
    Diabetes care, 2000, Volume: 23, Issue:7

    Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Cl

2000
Effect of myo-inositol on peripheral-nerve function in diabetes.
    Lancet (London, England), 1978, Dec-16, Volume: 2, Issue:8103

    Topics: Aged; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Neuropathies; Dose-Response Relationship

1978
The effect of aldose reductase inhibition on erythrocyte polyols and galactitol accumulation in diabetic patients.
    Diabetic medicine : a journal of the British Diabetic Association, 1989, Volume: 6, Issue:9

    Topics: Aldehyde Reductase; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus,

1989
The penetration of Sorbinil, an aldose reductase inhibitor, into lens, aqueous humour and erythrocytes of patients undergoing cataract extraction.
    Experimental eye research, 1985, Volume: 40, Issue:1

    Topics: Aged; Aldehyde Reductase; Aqueous Humor; Cataract Extraction; Chromatography, High Pressure Liquid;

1985
[Experiences in the treatment of diabetic retinopathies].
    Munchener medizinische Wochenschrift (1950), 1966, Dec-09, Volume: 108, Issue:49

    Topics: Clinical Trials as Topic; Diabetes Mellitus; Diabetic Retinopathy; Humans; Inositol; Rutin; Vitamin

1966

Other Studies

64 other studies available for inositol and Diabetes Mellitus

ArticleYear
Renoprotective potential of myo-inositol on diabetic kidney disease: Focus on the role of the PINK1/Parkin pathway and mitophagy receptors.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:6

    Topics: Animals; Diabetes Mellitus; Diabetic Nephropathies; Glucose; Inositol; Mitophagy; Protein Kinases; R

2022
Sinomenine alleviates diabetic peripheral neuropathic pain through inhibition of the inositol-requiring enzyme 1 alpha-X-box binding protein 1 pathway by downregulating prostaglandin-endoperoxide synthase 2.
    Journal of diabetes investigation, 2023, Volume: 14, Issue:3

    Topics: Animals; Cyclooxygenase 2; Diabetes Mellitus; Diabetic Neuropathies; Inositol; Microglia; Neuralgia;

2023
D-Pinitol Improved Glucose Metabolism and Inhibited Bone Loss in Mice with Diabetic Osteoporosis.
    Molecules (Basel, Switzerland), 2023, May-04, Volume: 28, Issue:9

    Topics: Animals; Biomarkers; Diabetes Mellitus; Glucose; Inositol; Mice; Osteoporosis

2023
Dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid in a patient with acquired reactive perforating collagenosis.
    The Journal of dermatology, 2018, Volume: 45, Issue:5

    Topics: Aged; Autoantigens; Biopsy; Collagen Diseases; Collagen Type XVII; Diabetes Mellitus; Dipeptidyl-Pep

2018
Clinical predictors of atheroma progression despite optimal glycemic control in early-stage diabetic patients with coronary artery disease: Insight from the DIANA study.
    Journal of atherosclerosis and thrombosis, 2014, Volume: 21, Issue:5

    Topics: Blood Glucose; Coronary Angiography; Coronary Artery Disease; Cyclohexanes; Diabetes Mellitus; Disea

2014
Lucica MI urinary myoinositol kit: a new diagnostic test for diabetes mellitus and glucose intolerance.
    Molecular diagnosis & therapy, 2008, Volume: 12, Issue:3

    Topics: Clinical Trials as Topic; Diabetes Mellitus; Glucose Intolerance; Glucose Tolerance Test; Humans; In

2008
[Assessment of therapeutic effect of losartan on diabetes mellitus with gas chromatography-based metabonomics].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2007, Volume: 29, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Albuminuria; Biomarkers; Chromatography, Gas; Creatinine; Deoxyguanosin

2007
Involvement of hyperglycemia in deposition of aggregated protein in glomeruli of diabetic mice.
    European journal of pharmacology, 2008, Dec-28, Volume: 601, Issue:1-3

    Topics: Animals; Blood Glucose; Diabetes Mellitus; Glucose; Glycated Hemoglobin; Glycated Serum Albumin; Gly

2008
Evaluation of serum and urine 1,5-anhydro-D-glucitol and myo-inositol concentrations in healthy dogs.
    The Journal of veterinary medical science, 2011, Volume: 73, Issue:9

    Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus; Dog Diseases; Dogs; Female; Inositol; Insul

2011
Intensive glucose lowering in cardiovascular risk management - unsolved questions - .
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:3

    Topics: Coronary Artery Disease; Cyclohexanes; Diabetes Mellitus; Female; Glycemic Index; Humans; Inositol;

2012
The renal excretion of inositol in normal and diabetic human beings.
    The Journal of clinical investigation, 1954, Volume: 33, Issue:3

    Topics: Body Fluids; Diabetes Mellitus; Humans; Inositol; Renal Elimination; Urine

1954
[Electrophoresis on paper. V. Effect of cholineinositol on blood lipids and proteins].
    Archivos de medicina experimental; trabajos del Instituto Nacional de Ciencias Medicas, 1955, Volume: 18, Issue:4

    Topics: Arteriosclerosis; Blood Proteins; Cholesterol; Choline; Diabetes Mellitus; Electrophoresis; Humans;

1955
[Electrophoresis on paper. V. Effect of cholineinositol on blood lipids and proteins].
    Archivos de medicina experimental; trabajos del Instituto Nacional de Ciencias Medicas, 1955, Volume: 18, Issue:4

    Topics: Arteriosclerosis; Blood Proteins; Cholesterol; Choline; Diabetes Mellitus; Electrophoresis; Humans;

1955
[Electrophoresis on paper. V. Effect of cholineinositol on blood lipids and proteins].
    Archivos de medicina experimental; trabajos del Instituto Nacional de Ciencias Medicas, 1955, Volume: 18, Issue:4

    Topics: Arteriosclerosis; Blood Proteins; Cholesterol; Choline; Diabetes Mellitus; Electrophoresis; Humans;

1955
[Electrophoresis on paper. V. Effect of cholineinositol on blood lipids and proteins].
    Archivos de medicina experimental; trabajos del Instituto Nacional de Ciencias Medicas, 1955, Volume: 18, Issue:4

    Topics: Arteriosclerosis; Blood Proteins; Cholesterol; Choline; Diabetes Mellitus; Electrophoresis; Humans;

1955
[Study of the urinary elimination of mesoinositol in diabetics].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1957, Volume: 151, Issue:11

    Topics: Body Fluids; Diabetes Mellitus; Humans; Inositol

1957
[Study of the urinary excretion of meso-inositol in various diseases].
    Bulletin de la Societe de chimie biologique, 1958, Volume: 40, Issue:5-6

    Topics: Body Fluids; Diabetes Mellitus; Humans; Inositol; Nephritis; Nephrosis

1958
[Serum meso-inositol: determination and normal and pathological values].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1959, Volume: 153, Issue:3

    Topics: Diabetes Mellitus; Disease; Humans; Inositol; Kidney; Muscles; Muscular Diseases; Nephritis

1959
THE EFFECT OF DIABETES ON THE CONTENT OF SORBITOL, GLUCOSE, FRUCTOSE AND INOSITOL IN THE HUMAN LENS.
    Experimental eye research, 1964, Volume: 3

    Topics: Aging; Cataract; Diabetes Mellitus; Fructose; Geriatrics; Glucose; Humans; Inositol; Lens, Crystalli

1964
EPIDEMIOLOGICAL AND BIOCHEMICAL STUDIES OF CATARACT AND DIABETES.
    Investigative ophthalmology, 1965, Volume: 4

    Topics: Carbohydrate Metabolism; Cataract; Cataract Extraction; Diabetes Mellitus; England; Epidemiology; Fr

1965
[Achieving better control of blood sugar--understanding of oral hypoglycemic agents according to their characteristics in pharmacological action mechanism (discussion)].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62, Issue:4

    Topics: Administration, Oral; Cardiovascular Diseases; Cyclohexanes; Diabetes Complications; Diabetes Mellit

2004
Depressing effect of inositol on serum cholesterol and lipid phosphorus in diabetics.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1949, Volume: 72, Issue:2

    Topics: Blood; Cholesterol; Diabetes Mellitus; Humans; Inositol; Lipids; Phosphorus

1949
[Myoinositol].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 11

    Topics: Diabetes Complications; Diabetes Mellitus; Humans; Inositol

2004
Pneumatosis cystoides intestinalis after alpha-glucosidase inhibitor treatment in a patient with interstitial pneumonitis.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:2

    Topics: Diabetes Mellitus; Enzyme Inhibitors; Female; Glucocorticoids; Glucosidases; Humans; Hypoglycemic Ag

2006
Nerve Na+-K+-ATPase, conduction, and myo-inositol in the insulin-deficient BB rat.
    The American journal of physiology, 1984, Volume: 247, Issue:4 Pt 1

    Topics: Adenosine Triphosphatases; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diuresis; Inosito

1984
Etiology of cataracts in diabetics.
    International ophthalmology clinics, 1984,Winter, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aldehyde Reductase; Animals; Blood Glucose; Cataract; Child; Child, Preschool; Di

1984
Free inositol, sorbitol and fructose levels in sciatic nerve.
    Diabetologia, 1983, Volume: 25, Issue:5

    Topics: Diabetes Mellitus; Fructose; Humans; Inositol; Reference Values; Sciatic Nerve; Sorbitol

1983
Free and lipid inositol, sorbitol and sugars in sciatic nerve obtained post-mortem from diabetic patients and control subjects.
    Diabetologia, 1983, Volume: 24, Issue:1

    Topics: Aged; Carbohydrate Metabolism; Diabetes Mellitus; Female; Fructose; Glucose; Humans; Inositol; Lipid

1983
Sorbitol, inositol and nerve conduction in diabetes.
    Life sciences, 1983, Apr-25, Volume: 32, Issue:17

    Topics: Animals; Diabetes Mellitus; Fructose; Glucose; Imidazoles; Imidazolidines; Inositol; Male; Mice; Mic

1983
Sorbitol and myoinositol levels in the cerebrospinal fluid of diabetic patients.
    Acta endocrinologica. Supplementum, 1980, Volume: 238

    Topics: Diabetes Mellitus; Humans; Inositol; Reference Values; Sorbitol

1980
Measurement of D-chiro-inositol in clinical studies.
    Diabetes care, 1995, Volume: 18, Issue:7

    Topics: Biomarkers; Diabetes Mellitus; Gas Chromatography-Mass Spectrometry; Glycosuria; Humans; Inositol; I

1995
D-chiro-inositol metabolism in diabetes mellitus.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21

    Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gas Chromatography-M

1993
Quantification of serum 1,5-anhydroglucitol in uremic and diabetic patients by liquid chromatography/mass spectrometry.
    Clinical chemistry, 1994, Volume: 40, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus; Female; Fru

1994
Sugar alcohols in the lens epithelium of age-related cataract.
    Experimental eye research, 1993, Volume: 56, Issue:1

    Topics: Aged; Blood Glucose; Cataract; Diabetes Mellitus; Epithelium; Female; Humans; Inositol; Lens, Crysta

1993
Inhibitory effect of voglibose and gymnemic acid on maltose absorption in vivo.
    World journal of gastroenterology, 2001, Volume: 7, Issue:2

    Topics: Animals; Diabetes Mellitus; Enzyme Inhibitors; Inositol; Intestine, Small; Male; Maltose; Rats; Rats

2001
Implications of aldose reductase in cataracts in human diabetes.
    Investigative ophthalmology & visual science, 1979, Volume: 18, Issue:3

    Topics: Aldehyde Reductase; Blood Glucose; Cataract; Diabetes Mellitus; Fructose; Glucose; Humans; Inositol;

1979
Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:6

    Topics: Animals; Diabetes Mellitus; Diabetic Neuropathies; Inositol; Insulin; Male; Neural Conduction; Perip

1975
The localisation of sorbitol pathway activity in the rat renal cortex and its relationship to the pathogenesis of the renal complications of diabetes mellitus.
    The Australian journal of experimental biology and medical science, 1975, Volume: 53, Issue:1

    Topics: Animals; Chromatography, Gas; Diabetes Mellitus; Diabetic Nephropathies; Fructose; Glucose; Inositol

1975
The effect of an unsaturated-fat diet on cataract formation in streptozotocin-induced diabetic rats.
    The British journal of nutrition, 1976, Volume: 36, Issue:2

    Topics: Animals; Aqueous Humor; Carbohydrate Metabolism; Cataract; Diabetes Mellitus; Dietary Fats; Eye; Fat

1976
Accumulation of myoinositol in plasma and red cells of diabetic patients.
    Acta medica Scandinavica, 1977, Volume: 201, Issue:1-2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Diabetes Mellitus; Erythrocytes; Glomerular Filtra

1977
Myoinositol metabolism in diabetes mellitus. Effect of insulin treatment.
    Diabetes, 1977, Volume: 26, Issue:3

    Topics: Adult; Diabetes Mellitus; Feces; Humans; Inositol; Insulin; Male

1977
Polyols in the cerebrospinal fluid and plasma of neurological, diabetic and uraemic patients.
    Acta neurologica Scandinavica, 1977, Volume: 56, Issue:2

    Topics: Diabetes Mellitus; Humans; Inositol; Ischemic Attack, Transient; Kidney Failure, Chronic; Mannitol;

1977
[Simple method of quantitative determination of myoinositol in the serum and urine].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1976, May-26, Volume: 31, Issue:17

    Topics: Chromatography, Paper; Densitometry; Diabetes Mellitus; Humans; Inositol; Kidney Diseases; Methods

1976
Changes in serum and urinary myo-inositol levels in chronic glomerulonephritis.
    Clinica chimica acta; international journal of clinical chemistry, 1976, Sep-20, Volume: 71, Issue:3

    Topics: Chronic Disease; Creatinine; Diabetes Mellitus; Glomerulonephritis; Humans; Inositol; Kidney Disease

1976
Gas chromatographic study of free polyols and aldoses in cataractous human lens tissue.
    Journal of chromatography, 1976, Nov-03, Volume: 126

    Topics: Cataract; Chromatography, Gas; Diabetes Mellitus; Galactose; Glucose; Humans; Inositol; Lens, Crysta

1976
Quantitatively minor areas of metabolism of both sugar alcohols and sugars.
    Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Beiheft, 1976, Volume: 15

    Topics: Animals; Carbohydrate Metabolism; Diabetes Mellitus; Glucosamine; Glucose; Inositol; Sorbitol; Sugar

1976
Sorbitol and other polyols in lens, adipose tissue and urine in diabetes mellitus.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Aug-18, Volume: 63, Issue:1

    Topics: Adipose Tissue; Cataract; Chromatography, Gas; Diabetes Mellitus; Fructose; Glucose; Humans; Inosito

1975
Variation in polyol levels in cerebrospinal fluid and serum in diabetic patients.
    Diabetologia, 1975, Volume: 11, Issue:6

    Topics: Aged; Blood Glucose; Creatinine; Deoxyglucose; Diabetes Mellitus; Diabetic Nephropathies; Ethers, Cy

1975
Serum-free and protein-bound sugars and cardiovascular complications in diabetes mellitus.
    Laboratory investigation; a journal of technical methods and pathology, 1976, Volume: 34, Issue:2

    Topics: Adult; Age Factors; Aged; Analysis of Variance; Blood Glucose; Blood Pressure; Cardiovascular Diseas

1976
Cerebral metabolic disturbances in patients with subacute and chronic diabetes mellitus: detection with proton MR spectroscopy.
    Radiology, 1992, Volume: 184, Issue:1

    Topics: Adult; Aged; Brain; Chronic Disease; Diabetes Mellitus; Diabetic Ketoacidosis; Female; Glucose; Huma

1992
Effect of Mg2+ on Na(+)-dependent inositol transport. Role for Mg2+ in etiology of diabetic complications.
    Diabetes, 1992, Volume: 41, Issue:1

    Topics: Biological Transport; Cell Line; Diabetes Complications; Diabetes Mellitus; Humans; Inositol; Kineti

1992
[Abnormal metabolism of polyol pathway and diabetic complications].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Inositol; NADP; Osmotic Pressure; Polymers

1991
Advances in the diagnosis and pathogenesis of diabetes mellitus and its complications.
    Comprehensive therapy, 1990, Volume: 16, Issue:7

    Topics: Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dia

1990
[Diabetes markers (1)--with special reference to alpha(1)-microglobulin, beta(2)-microglobulin, N-acetyl glucosaminidase, myoinositol and 1,5-anhydroglucitol].
    Josai Shika Daigaku kiyo. The Bulletin of the Josai Dental University, 1986, Volume: 15, Issue:3

    Topics: Acetylglucosaminidase; Alpha-Globulins; beta 2-Microglobulin; Deoxy Sugars; Deoxyglucose; Diabetes M

1986
[Significance of inositol analysis in clinical tests].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 48 Suppl

    Topics: Animals; Biological Assay; Chromatography, Gas; Diabetes Mellitus; Humans; Inositol; Kidney Failure,

1989
[Diabetic polyneuropathy].
    Klinicheskaia meditsina, 1989, Volume: 67, Issue:4

    Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Humans; Hyperglycemia; Inositol; P

1989
High-dose dietary myo-inositol supplementation does not alter the ischaemia phenomenon in human diabetics.
    Acta neurologica Scandinavica, 1989, Volume: 80, Issue:2

    Topics: Adolescent; Adult; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Dose-Response R

1989
Nerve glucose, fructose, sorbitol, myo-inositol, and fiber degeneration and regeneration in diabetic neuropathy.
    The New England journal of medicine, 1988, Sep-01, Volume: 319, Issue:9

    Topics: Adolescent; Adult; Aged; Aldehyde Reductase; Diabetes Mellitus; Diabetic Neuropathies; Erythrocytes;

1988
Motor nerve conduction velocity and nerve polyols in mice with short-term genetic or streptozotocin-induced diabetes.
    Experimental neurology, 1985, Volume: 89, Issue:2

    Topics: Acute Disease; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Female; Fructose; Glucos

1985
Measurement of myo-inositol in diabetic sera by GC/MS/SIM using n-butylboronate derivatives.
    Clinica chimica acta; international journal of clinical chemistry, 1988, Aug-31, Volume: 176, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Boron Compounds; Boronic Acids; Chromatography, Paper; D

1988
Peripheral nerve concentrations of glucose, fructose, sorbitol and myoinositol in diabetic and non-diabetic patients.
    Diabetologia, 1987, Volume: 30, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Carbohydrate Metabolism; Diabetes Mellitus; Female; Fructose; Glucos

1987
Secondary changes in diabetes mellitus with particular reference to retinopathy and neuropathy.
    Medical hypotheses, 1985, Volume: 17, Issue:4

    Topics: Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Glucose; Humans; Hypoxia; Inositol

1985
The cerebrospinal fluid in uncontrolled diabetes mellitus.
    The American journal of the medical sciences, 1973, Volume: 266, Issue:3

    Topics: Adolescent; Adult; Aged; Alcohol Oxidoreductases; Blood Glucose; Diabetes Mellitus; Diabetic Ketoaci

1973
Sorbitol metabolism in the retina: accumulation of pathway intermediates in streptozotocin induced diabetes in the rat.
    The Australian journal of experimental biology and medical science, 1974, Volume: 52, Issue:2

    Topics: Animals; Aqueous Humor; Blood Glucose; Chromatography, Gas; Diabetes Mellitus; Fatty Acids, Nonester

1974
The absence of cataracts in mice with congenital hyperglycemia.
    Experimental eye research, 1974, Volume: 19, Issue:6

    Topics: Alcohol Oxidoreductases; Animals; Cataract; Diabetes Mellitus; Diet; Fructose; Galactitol; Galactose

1974
Monosaccharides and polyols in diabetes mellitus and uremia.
    The Journal of laboratory and clinical medicine, 1973, Volume: 82, Issue:5

    Topics: Adult; Aged; Blood Glucose; Chromatography, Gas; Diabetes Mellitus; Female; Fructose; Humans; Inosit

1973
The serum polyol pattern and the urinary polyol excretion in diabetic and in uremic patients.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 38, Issue:1

    Topics: Acetobacter; Biological Assay; Borohydrides; Chromatography, Gas; Chromatography, Paper; Diabetes Me

1972