inositol has been researched along with Cystic Fibrosis in 4 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Activation of the inositol cycle by a factor capable of by-passing the normal controls on exocrine secretion by an interaction with a coupling protein could produce effects similar to a calcium ionophore or the ciliary dyskinesia factor." | 7.67 | The end organ defect in cystic fibrosis; a hypothesis: disinhibited inositol cycle activation? ( van Woerkom, AE, 1987) |
| "Activation of the inositol cycle by a factor capable of by-passing the normal controls on exocrine secretion by an interaction with a coupling protein could produce effects similar to a calcium ionophore or the ciliary dyskinesia factor." | 3.67 | The end organ defect in cystic fibrosis; a hypothesis: disinhibited inositol cycle activation? ( van Woerkom, AE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ribeiro, CMP | 1 |
| Hull-Ryde, EA | 1 |
| HOKIN, LE | 2 |
| HOKIN, MR | 1 |
| LOBECK, CC | 2 |
| van Woerkom, AE | 1 |
| Gerber, DE | 1 |
1 review available for inositol and Cystic Fibrosis
| Article | Year |
|---|---|
Functional role of the ER stress transducer IRE1α in CF airway epithelial inflammation.
Topics: Cystic Fibrosis; Endoplasmic Reticulum Stress; Endoribonucleases; Humans; Inflammation; Inositol; Pr | 2022 |
3 other studies available for inositol and Cystic Fibrosis
| Article | Year |
|---|---|
EFFECTS OF ACETYLCHOLINE ON THE INCORPORATION OF P32 INTO THE PHOSPHOLIPIDS IN SLICES OF SKIN FROM CHILDREN WITH AND WITHOUT CYSTIC FIBROSIS OF THE PANCREAS.
Topics: Acetylcholine; Biopsy; Child; Cystic Fibrosis; Humans; Inositol; Iontophoresis; Lipid Metabolism; Ph | 1963 |
The end organ defect in cystic fibrosis; a hypothesis: disinhibited inositol cycle activation?
Topics: Blood Proteins; Calcium; Cell Membrane Permeability; Chlorides; Ciliary Motility Disorders; Cystic F | 1987 |
Radioautographic localization of the acetylcholine-stimulated synthesis of phosphatidylinositol in skin from patients with and without cystic fibrosis.
Topics: Acetylcholine; Adult; Autoradiography; Child; Child, Preschool; Chloroform; Cystic Fibrosis; Cytopla | 1971 |