inositol has been researched along with Complications of Diabetes Mellitus in 28 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a patient with neuropsychiatric systemic lupus erythematosus (NPSLE) complicated by diabetes mellitus (DM) who showed pneumatosis cystoides intestinalis (PCI) while being treated with prednisolone (PSL) and an alpha-glucosidase inhibitor (αGI)." | 4.87 | Pneumatosis cystoides intestinalis in neuropsychiatric systemic lupus erythematosus with diabetes mellitus: case report and literature review. ( Ikeda, S; Ishii, W; Matsuda, M; Shimojima, Y; Tojo, K; Watanabe, R, 2011) |
| "Postprandial hyperglycemia is frequently associated with visceral obesity which plays a key role in metabolic abnormalities such as dyslipidemia and hypertension." | 2.42 | [Pharmacological treatment of postprandial hyperglycemia in hypertensive patients with type 2 diabetes mellitus]. ( Yamada, K, 2003) |
| "LV functional parameters and the reactive hyperemia index also remained unchanged after the 24-week treatment." | 1.48 | Effect of Sitagliptin on Coronary Flow Reserve Assessed by Magnetic Resonance Imaging in Type 2 Diabetic Patients With Coronary Artery Disease. ( Dohi, K; Fujimoto, N; Ishida, M; Ito, M; Kumagai, N; Masuda, J; Moriwaki, K; Nakamori, S; Nakamura, M; Sakuma, H; Sato, Y; Sawai, T; Takeuchi, T; Yamada, N, 2018) |
| "Diabetic gastroparesis is a common complication of diabetes mellitus (DM) that is characterized by decreased serum insulin and insulin-like growth factor-1 (IGF-1)." | 1.46 | Impaired insulin/IGF-1 is responsible for diabetic gastroparesis by damaging myenteric cholinergic neurones and interstitial cells of Cajal. ( Han, K; Ji, F; Li, D; Sun, H; Sun, T; Wu, B; Yang, S; Zhang, G; Zhou, D, 2017) |
| "Patients with type 2 diabetes and major depression (n=20) were scanned along with patients with diabetes alone (n=24) and healthy controls (n=21) on a 1." | 1.34 | Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy. ( Ajilore, O; Binesh, N; Darwin, C; Haroon, E; Kumar, A; Kumaran, S; Miller, J; Mintz, J; Thomas, MA, 2007) |
| "Diabetes mellitus is associated with a significant reduction in the serum concentration of Mg2+." | 1.28 | Effect of Mg2+ on Na(+)-dependent inositol transport. Role for Mg2+ in etiology of diabetic complications. ( Baxter, MA; Brown, G; Bunce, CM; Grafton, G; Sheppard, MC, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (42.86) | 18.7374 |
| 1990's | 4 (14.29) | 18.2507 |
| 2000's | 6 (21.43) | 29.6817 |
| 2010's | 5 (17.86) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Guimarães, VHD | 1 |
| Basilio Silva, JN | 1 |
| de Freitas, DF | 1 |
| Filho, OC | 1 |
| da Silveira, LH | 1 |
| Marinho, BM | 1 |
| de Paula, AMB | 1 |
| Melo, GA | 1 |
| Santos, SHS | 1 |
| Yang, S | 1 |
| Wu, B | 1 |
| Sun, H | 1 |
| Sun, T | 1 |
| Han, K | 1 |
| Li, D | 1 |
| Ji, F | 1 |
| Zhang, G | 1 |
| Zhou, D | 1 |
| Moriwaki, K | 1 |
| Takeuchi, T | 1 |
| Fujimoto, N | 1 |
| Sawai, T | 1 |
| Sato, Y | 1 |
| Kumagai, N | 1 |
| Masuda, J | 1 |
| Nakamori, S | 1 |
| Ishida, M | 1 |
| Yamada, N | 1 |
| Nakamura, M | 1 |
| Sakuma, H | 1 |
| Ito, M | 1 |
| Dohi, K | 1 |
| Shimojima, Y | 1 |
| Ishii, W | 1 |
| Matsuda, M | 1 |
| Tojo, K | 1 |
| Watanabe, R | 1 |
| Ikeda, S | 1 |
| Kataoka, Y | 1 |
| Yasuda, S | 1 |
| Miyamoto, Y | 1 |
| Sase, K | 1 |
| Kosuge, M | 1 |
| Kimura, K | 1 |
| Yoshimasa, Y | 1 |
| Miyazaki, S | 1 |
| Standl, E | 1 |
| Schnell, O | 1 |
| Eriksson, UJ | 1 |
| Cederberg, J | 1 |
| Wentzel, P | 1 |
| Yamada, K | 1 |
| HILGARTNER, HL | 1 |
| Kawamori, R | 1 |
| Kadowaki, T | 1 |
| Ishida, H | 1 |
| Yamanouchi, T | 1 |
| Ajilore, O | 1 |
| Haroon, E | 1 |
| Kumaran, S | 1 |
| Darwin, C | 1 |
| Binesh, N | 1 |
| Mintz, J | 1 |
| Miller, J | 1 |
| Thomas, MA | 1 |
| Kumar, A | 1 |
| Thorsell, AG | 1 |
| Persson, C | 1 |
| Voevodskaya, N | 1 |
| Busam, RD | 1 |
| Hammarström, M | 1 |
| Gräslund, S | 1 |
| Gräslund, A | 1 |
| Hallberg, BM | 1 |
| Varma, SD | 2 |
| Richards, RD | 1 |
| Zhao, W | 1 |
| Devamanoharan, PS | 1 |
| Radhakrishnamurthy, B | 1 |
| Berenson, GS | 1 |
| Pargaonkar, PS | 1 |
| Voors, AW | 1 |
| Srinivasan, SR | 1 |
| Plavidal, F | 1 |
| Dolan, P | 1 |
| Dalferes, ER | 1 |
| Borejszo, I | 1 |
| Grafton, G | 1 |
| Bunce, CM | 1 |
| Sheppard, MC | 1 |
| Brown, G | 1 |
| Baxter, MA | 1 |
| Moller, DE | 1 |
| Moses, AC | 1 |
| Balabolkin, MI | 1 |
| Islambekov, RR | 1 |
| Arendrup, K | 1 |
| Gregersen, G | 1 |
| Hawley, J | 1 |
| Hawthorne, JN | 1 |
| Greene, DA | 3 |
| Lattimer, SA | 2 |
| Winegrad, AI | 1 |
| Sima, AA | 1 |
| Clements, RS | 1 |
| Broekhuyse, RM | 1 |
| Pisi, E | 1 |
| Bianchi, FB | 1 |
| Nigro, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Quercetin in Type 2 Diabetes: Impact on Glucose Tolerance and Postprandial Endothelial Function.[NCT01839344] | Phase 2 | 19 participants (Actual) | Interventional | 2013-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for inositol and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Pneumatosis cystoides intestinalis in neuropsychiatric systemic lupus erythematosus with diabetes mellitus: case report and literature review.
Topics: Diabetes Complications; Drug Therapy, Combination; Glucocorticoids; Humans; Hypoglycemic Agents; Ino | 2011 |
Alpha-glucosidase inhibitors 2012 - cardiovascular considerations and trial evaluation.
Topics: 1-Deoxynojirimycin; Acarbose; Cardiovascular Diseases; Diabetes Complications; Glycoside Hydrolase I | 2012 |
Congenital malformations in offspring of diabetic mothers--animal and human studies.
Topics: Animals; Arachidonic Acid; Congenital Abnormalities; Diabetes Complications; Female; Gene Expression | 2003 |
[Pharmacological treatment of postprandial hyperglycemia in hypertensive patients with type 2 diabetes mellitus].
Topics: Acarbose; Cyclohexanes; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Enzyme | 2003 |
[Role of the polyol cycle and disturbances of myoinositol metabolism in pathogenesis of chronic complications in diabetes mellitus].
Topics: Ampholyte Mixtures; Animals; Chronic Disease; Diabetes Complications; Humans; Inositol; Periodicity; | 1992 |
Acute and chronic complications of diabetes mellitus in older patients.
Topics: Adult; Aged; Aging; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Diabetic Coma; Diabet | 1986 |
Biochemical alterations and complications in diabetes.
Topics: Biological Transport; Diabetes Complications; Diabetes Mellitus; Energy Metabolism; Glucose; Humans; | 1986 |
Sorbitol, phosphoinositides, and sodium-potassium-ATPase in the pathogenesis of diabetic complications.
Topics: Animals; Diabetes Complications; Humans; Inositol; Phosphatidylinositols; Protein Kinase C; Rats; So | 1987 |
New therapies for the chronic complications of older diabetic patients.
Topics: Aged; Aldehyde Reductase; Blood Glucose; Cell Membrane Permeability; Coronary Disease; Diabetes Comp | 1986 |
1 trial available for inositol and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Effects of voglibose and nateglinide on glycemic status and coronary atherosclerosis in early-stage diabetic patients.
Topics: Aged; Coronary Artery Disease; Cyclohexanes; Diabetes Complications; Diabetes Mellitus; Female; Glyc | 2012 |
18 other studies available for inositol and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Hydroalcoholic Extract of Solanum lycocarpum A. St. Hil. (Solanaceae) Leaves Improves Alloxan-Induced Diabetes Complications in Mice.
Topics: Alanine Transaminase; Alkaline Phosphatase; Alloxan; alpha-Tocopherol; Animals; Aspartate Aminotrans | 2021 |
Impaired insulin/IGF-1 is responsible for diabetic gastroparesis by damaging myenteric cholinergic neurones and interstitial cells of Cajal.
Topics: Animals; Antigens, CD; Choline O-Acetyltransferase; Cholinergic Neurons; Diabetes Complications; Dis | 2017 |
Effect of Sitagliptin on Coronary Flow Reserve Assessed by Magnetic Resonance Imaging in Type 2 Diabetic Patients With Coronary Artery Disease.
Topics: Aged; Coronary Artery Disease; Coronary Circulation; Diabetes Complications; Diabetes Mellitus, Type | 2018 |
Diabetic retinopathies, effect of lipotropic substances (lipotriad) in treatment.
Topics: Choline; Diabetes Complications; Diabetic Retinopathy; Disease; Fats; Humans; Inositol; Lipid Metabo | 1955 |
[Achieving better control of blood sugar--understanding of oral hypoglycemic agents according to their characteristics in pharmacological action mechanism (discussion)].
Topics: Administration, Oral; Cardiovascular Diseases; Cyclohexanes; Diabetes Complications; Diabetes Mellit | 2004 |
[Myoinositol].
Topics: Diabetes Complications; Diabetes Mellitus; Humans; Inositol | 2004 |
Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Choline; Creatine; Depressive Disord | 2007 |
Structural and biophysical characterization of human myo-inositol oxygenase.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Diabetes Complications; Humans; Inositol | 2008 |
Etiology of cataracts in diabetics.
Topics: Adolescent; Adult; Aldehyde Reductase; Animals; Blood Glucose; Cataract; Child; Child, Preschool; Di | 1984 |
Fructose induced deactivation of glucose-6-phosphate dehydrogenase activity and its prevention by pyruvate: implications in cataract prevention.
Topics: Animals; Catalase; Cataract; Cytochrome c Group; Diabetes Complications; Dose-Response Relationship, | 1998 |
Serum-free and protein-bound sugars and cardiovascular complications in diabetes mellitus.
Topics: Adult; Age Factors; Aged; Analysis of Variance; Blood Glucose; Blood Pressure; Cardiovascular Diseas | 1976 |
Effect of Mg2+ on Na(+)-dependent inositol transport. Role for Mg2+ in etiology of diabetic complications.
Topics: Biological Transport; Cell Line; Diabetes Complications; Diabetes Mellitus; Humans; Inositol; Kineti | 1992 |
Advances in the diagnosis and pathogenesis of diabetes mellitus and its complications.
Topics: Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dia | 1990 |
[Diabetic polyneuropathy].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Humans; Hyperglycemia; Inositol; P | 1989 |
High-dose dietary myo-inositol supplementation does not alter the ischaemia phenomenon in human diabetics.
Topics: Adolescent; Adult; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Dose-Response R | 1989 |
Banting lecture 1986. Does a common mechanism induce the diverse complications of diabetes?
Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Ne | 1987 |
Changes in myo-inositol permeability in the lens due to cataractous conditions.
Topics: Alcohols; Animals; Cataract; Diabetes Complications; Female; Galactosemias; Inositol; Lens, Crystall | 1968 |
[Considerations on the therapy of hepatic steatosis].
Topics: Adult; Aged; Alcoholism; Choline; Colitis, Ulcerative; Diabetes Complications; Fatty Liver; Gout; He | 1969 |