Page last updated: 2024-10-19

inositol and Complications, Pregnancy

inositol has been researched along with Complications, Pregnancy in 15 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
"Inositols (INOs) supplementation during pregnancy, specifically the combination of myo-inositol (MI) and D-chiro-inositol (DCI), has been reported to improve vascular parameters in women with gestational diabetes mellitus."7.91Vascular and metabolic profiles in offspring born to pregnant mice with metabolic syndrome treated with inositols. ( Alrais, M; Blackwell, SC; Facchinetti, F; Ferrari, F; Longo, M; Refuerzo, JS; Sibai, BM; Tamayo, EH, 2019)
"Authors would like to demonstrate the beneficial effect of myo-inositol supplementation in a pregnant woman with insulin-dependent type 2 diabetes mellitus and polycystic ovary syndrome."7.85[The myo-inositol is beneficial in the therapy of pregnancy with insulin-dependent type 2 diabetes and polycystic ovary syndrome]. ( Kun, A; Tornóczky, J, 2017)
"Myoinositol and D-chiroinositol improve insulin resistance in women with obesity and gestational diabetes and in postmenopausal women with metabolic syndrome."7.83The effect of combined inositol supplementation on maternal metabolic profile in pregnancies complicated by metabolic syndrome and obesity. ( Blackwell, SC; Facchinetti, F; Ferrari, F; Longo, M; Ontiveros, AE; Refuerzo, JS; Roberts, RP; Saade, MM; Sibai, BM, 2016)
"To investigate myo-inositol, glucose and zinc status in mothers and their infants on cleft lip with or without cleft palate risk (CLP)."7.72Myo-inositol, glucose and zinc status as risk factors for non-syndromic cleft lip with or without cleft palate in offspring: a case-control study. ( Brussel, W; Krapels, IP; Rooij, IA; Spauwen, PH; Steegers-Theunissen, RP; Wevers, RA; Zielhuis, GA, 2004)
"Inositols (INOs) supplementation during pregnancy, specifically the combination of myo-inositol (MI) and D-chiro-inositol (DCI), has been reported to improve vascular parameters in women with gestational diabetes mellitus."3.91Vascular and metabolic profiles in offspring born to pregnant mice with metabolic syndrome treated with inositols. ( Alrais, M; Blackwell, SC; Facchinetti, F; Ferrari, F; Longo, M; Refuerzo, JS; Sibai, BM; Tamayo, EH, 2019)
"Authors would like to demonstrate the beneficial effect of myo-inositol supplementation in a pregnant woman with insulin-dependent type 2 diabetes mellitus and polycystic ovary syndrome."3.85[The myo-inositol is beneficial in the therapy of pregnancy with insulin-dependent type 2 diabetes and polycystic ovary syndrome]. ( Kun, A; Tornóczky, J, 2017)
"Myoinositol and D-chiroinositol improve insulin resistance in women with obesity and gestational diabetes and in postmenopausal women with metabolic syndrome."3.83The effect of combined inositol supplementation on maternal metabolic profile in pregnancies complicated by metabolic syndrome and obesity. ( Blackwell, SC; Facchinetti, F; Ferrari, F; Longo, M; Ontiveros, AE; Refuerzo, JS; Roberts, RP; Saade, MM; Sibai, BM, 2016)
"To evaluate retrospectively the prevalence of gestational diabetes (GD) in pregnancies obtained with myo-inositol administration in women with polycystic ovary syndrome."3.78Myo-inositol may prevent gestational diabetes in PCOS women. ( Corrado, F; D'Anna, R; Di Benedetto, A; Di Benedetto, V; Interdonato, ML; Raffone, E; Rizzo, P, 2012)
"To investigate myo-inositol, glucose and zinc status in mothers and their infants on cleft lip with or without cleft palate risk (CLP)."3.72Myo-inositol, glucose and zinc status as risk factors for non-syndromic cleft lip with or without cleft palate in offspring: a case-control study. ( Brussel, W; Krapels, IP; Rooij, IA; Spauwen, PH; Steegers-Theunissen, RP; Wevers, RA; Zielhuis, GA, 2004)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's7 (46.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Plows, JF1
Ramos Nieves, JM1
Budin, F1
Mace, K1
Reynolds, CM1
Vickers, MH1
Silva-Zolezzi, I1
Baker, PN1
Stanley, JL1
Kun, A1
Tornóczky, J1
Longo, M2
Alrais, M1
Tamayo, EH1
Ferrari, F2
Facchinetti, F2
Refuerzo, JS2
Blackwell, SC2
Sibai, BM2
Metges, CC1
Görs, S1
Lang, IS1
Hammon, HM1
Brüssow, KP1
Weitzel, JM1
Nürnberg, G1
Rehfeldt, C1
Otten, W1
Li, Q1
Leung, YO1
Zhou, I1
Ho, LC1
Kong, W1
Basil, P1
Wei, R1
Lam, S1
Zhang, X1
Law, AC1
Chua, SE1
Sham, PC1
Wu, EX1
McAlonan, GM1
Ontiveros, AE1
Roberts, RP1
Saade, MM1
D'Anna, R1
Di Benedetto, V1
Rizzo, P1
Raffone, E1
Interdonato, ML1
Corrado, F1
Di Benedetto, A1
Staat, BC1
Galan, HL1
Harwood, JE1
Lee, G1
Marconi, AM1
Paolini, CL1
Cheung, A1
Battaglia, FC1
BALESTRI, F1
BONINO, A1
Krapels, IP1
Rooij, IA1
Wevers, RA1
Zielhuis, GA1
Spauwen, PH1
Brussel, W1
Steegers-Theunissen, RP1
Gojnic, M1
Pervulov, M1
Burton, LE2
Wells, WW2
Brivet, M1
Migayron, F1
Roger, J1
Cheron, G1
Lemonnier, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT01511822]Phase 40 participants InterventionalCompleted
Reduction of Insulin Therapy Under Myo-inositol for the Treatment of Gestational Diabetes Mellitus: a Randomized Multicenter and Prospective Trial. MYO-GDM Study[NCT03875755]1,080 participants (Anticipated)Interventional2020-03-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for inositol and Complications, Pregnancy

ArticleYear
Artificial fetal lung maturation--prevention of antenatal complications in premature deliveries.
    Clinical and experimental obstetrics & gynecology, 2005, Volume: 32, Issue:1

    Topics: Adrenergic beta-Agonists; Aminophylline; Bronchodilator Agents; Drug Administration Schedule; Female

2005

Trials

1 trial available for inositol and Complications, Pregnancy

ArticleYear
Transplacental supply of mannose and inositol in uncomplicated pregnancies using stable isotopes.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:7

    Topics: Adult; Carbon Isotopes; Cesarean Section; Female; Humans; Hydrogen; Infant, Newborn; Inositol; Isoto

2012

Other Studies

13 other studies available for inositol and Complications, Pregnancy

ArticleYear
The effects of myo-inositol and probiotic supplementation in a high-fat-fed preclinical model of glucose intolerance in pregnancy.
    The British journal of nutrition, 2020, 03-14, Volume: 123, Issue:5

    Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes, Gestational; Diet, High-Fat; Dietary Supplements;

2020
[The myo-inositol is beneficial in the therapy of pregnancy with insulin-dependent type 2 diabetes and polycystic ovary syndrome].
    Orvosi hetilap, 2017, Volume: 158, Issue:14

    Topics: Adult; Diabetes Mellitus, Type 1; Female; Humans; Infant, Newborn; Inositol; Polycystic Ovary Syndro

2017
Vascular and metabolic profiles in offspring born to pregnant mice with metabolic syndrome treated with inositols.
    American journal of obstetrics and gynecology, 2019, Volume: 220, Issue:3

    Topics: Animals; Biomarkers; Drug Administration Schedule; Female; Hypertension; Inositol; Male; Metabolic S

2019
Low and high dietary protein:carbohydrate ratios during pregnancy affect materno-fetal glucose metabolism in pigs.
    The Journal of nutrition, 2014, Volume: 144, Issue:2

    Topics: Adaptation, Physiological; Animals; Area Under Curve; Blood Glucose; Brain; Diet; Diet, Carbohydrate

2014
Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model.
    Translational psychiatry, 2015, Sep-22, Volume: 5

    Topics: Animals; Aspartic Acid; Behavior, Animal; Creatine; Diet, High-Fat; Dietary Supplements; Fatty Acids

2015
The effect of combined inositol supplementation on maternal metabolic profile in pregnancies complicated by metabolic syndrome and obesity.
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:4

    Topics: Animals; Biomarkers; Blood Glucose; Dietary Supplements; Disease Models, Animal; Female; Gastric Inh

2016
Myo-inositol may prevent gestational diabetes in PCOS women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:6

    Topics: Adult; Diabetes, Gestational; Female; Humans; Hypoglycemic Agents; Inositol; Metformin; Polycystic O

2012
Myo-inositol may prevent gestational diabetes in PCOS women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:6

    Topics: Adult; Diabetes, Gestational; Female; Humans; Hypoglycemic Agents; Inositol; Metformin; Polycystic O

2012
Myo-inositol may prevent gestational diabetes in PCOS women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:6

    Topics: Adult; Diabetes, Gestational; Female; Humans; Hypoglycemic Agents; Inositol; Metformin; Polycystic O

2012
Myo-inositol may prevent gestational diabetes in PCOS women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:6

    Topics: Adult; Diabetes, Gestational; Female; Humans; Hypoglycemic Agents; Inositol; Metformin; Polycystic O

2012
[Treatment of hyperemesis gravidarum with combined inositol and pyridoxine].
    Gazzetta medica italiana, 1955, Volume: 114, Issue:10

    Topics: Female; Humans; Hyperemesis Gravidarum; Inositol; Pregnancy; Pregnancy Complications; Pyridoxine; Vi

1955
[Inositol in vomiting in pregnancy].
    Minerva ginecologica, 1956, Feb-29, Volume: 8, Issue:4

    Topics: Female; Humans; Inositol; Pregnancy; Pregnancy Complications; Vomiting

1956
Myo-inositol, glucose and zinc status as risk factors for non-syndromic cleft lip with or without cleft palate in offspring: a case-control study.
    BJOG : an international journal of obstetrics and gynaecology, 2004, Volume: 111, Issue:7

    Topics: Adult; Blood Glucose; Case-Control Studies; Cleft Lip; Cleft Palate; Dietary Supplements; Erythrocyt

2004
Characterization of the lactation-dependent fatty liver in myo-inositol deficient rats.
    The Journal of nutrition, 1977, Volume: 107, Issue:10

    Topics: Animals; Cholesterol; Cholesterol Esters; Fatty Liver; Female; Inositol; Lactation; Lipid Metabolism

1977
myo-Inositol metabolism during lactation and development in the rat. The prevention of lactation-induced fatty liver by dietary myo-inositol.
    The Journal of nutrition, 1976, Volume: 106, Issue:11

    Topics: Amniotic Fluid; Animals; Body Weight; Disaccharides; Fatty Liver; Female; Galactose; Inositol; Lacta

1976
Lens hexitols and cataract formation during lactation in a woman heterozygote for galactosaemia.
    Journal of inherited metabolic disease, 1989, Volume: 12 Suppl 2

    Topics: Adult; Cataract; Female; Galactitol; Galactokinase; Galactosemias; Genetic Carrier Screening; Humans

1989