inositol has been researched along with Colorectal Neoplasms in 8 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inositol hexaphosphate (IP6), a widely found natural bioactive substance in grains, effectively inhibits the progression of colorectal cancer (CRC) when used in combination with inositol (INS)." | 8.31 | The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7. ( Chen, Z; Han, Y; Lan, T; Li, H; Ma, X; Song, Y; Tao, M; Wang, C; Wang, H; Xu, Z; Yang, N, 2023) |
| "To investigate the effects of inositol hexaphosphate (IP6) and inositol (INS) with capecitabine treatment on colorectal cancer (CRC) growth and liver metastasis in mice, we established an orthotopic xenograft mouse model." | 8.02 | Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model. ( Chen, C; Ci, Y; Li, C; Li, Q; Li, X; Liu, C; Liu, X; Song, Y, 2021) |
| "The inositol compounds were administered via the drinking fluid." | 5.34 | Inhibition of chronic ulcerative colitis associated adenocarcinoma development in mice by inositol compounds. ( Liao, J; Lu, GG; Seril, DN; Yang, AL; Yang, GY, 2007) |
| "Inositol hexaphosphate (IP6), a widely found natural bioactive substance in grains, effectively inhibits the progression of colorectal cancer (CRC) when used in combination with inositol (INS)." | 4.31 | The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7. ( Chen, Z; Han, Y; Lan, T; Li, H; Ma, X; Song, Y; Tao, M; Wang, C; Wang, H; Xu, Z; Yang, N, 2023) |
| "To investigate the effects of inositol hexaphosphate (IP6) and inositol (INS) with capecitabine treatment on colorectal cancer (CRC) growth and liver metastasis in mice, we established an orthotopic xenograft mouse model." | 4.02 | Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model. ( Chen, C; Ci, Y; Li, C; Li, Q; Li, X; Liu, C; Liu, X; Song, Y, 2021) |
| "Chronic inflammation is a well-recognized risk factor for the development of human cancer." | 1.35 | Inflammatory bowel disease: a model of chronic inflammation-induced cancer. ( Liao, J; Taboada, S; Yang, GY, 2009) |
| "The inositol compounds were administered via the drinking fluid." | 1.34 | Inhibition of chronic ulcerative colitis associated adenocarcinoma development in mice by inositol compounds. ( Liao, J; Lu, GG; Seril, DN; Yang, AL; Yang, GY, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, Y | 1 |
| Lan, T | 1 |
| Ma, X | 1 |
| Yang, N | 1 |
| Wang, C | 1 |
| Xu, Z | 1 |
| Chen, Z | 1 |
| Tao, M | 1 |
| Li, H | 1 |
| Wang, H | 1 |
| Song, Y | 3 |
| Li, C | 1 |
| Ci, Y | 1 |
| Liu, X | 1 |
| Chen, C | 1 |
| Liu, C | 1 |
| Li, X | 1 |
| Li, Q | 1 |
| Bradford, EM | 1 |
| Thompson, CA | 1 |
| Goretsky, T | 1 |
| Yang, GY | 3 |
| Rodriguez, LM | 1 |
| Li, L | 1 |
| Barrett, TA | 1 |
| Fu, M | 1 |
| Wen, Z | 1 |
| Lu, X | 1 |
| Cui, L | 1 |
| Taboada, S | 1 |
| Liao, J | 2 |
| Schröterová, L | 1 |
| Hasková, P | 1 |
| Rudolf, E | 1 |
| Cervinka, M | 1 |
| Seril, DN | 1 |
| Yang, AL | 1 |
| Lu, GG | 1 |
| Fedier, A | 1 |
| Erdmann, R | 1 |
| Boulikas, T | 1 |
| Fink, D | 1 |
1 trial available for inositol and Colorectal Neoplasms
| Article | Year |
|---|---|
Myo-inositol reduces β-catenin activation in colitis.
Topics: Animals; beta Catenin; Biomarkers, Tumor; Biopsy; Cell Nucleus; Cell Proliferation; Colitis, Ulcerat | 2017 |
7 other studies available for inositol and Colorectal Neoplasms
| Article | Year |
|---|---|
The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7.
Topics: Animals; Cell Line, Tumor; Claudins; Colonic Neoplasms; Colorectal Neoplasms; Epithelial-Mesenchymal | 2023 |
Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model.
Topics: Animals; Capecitabine; Colorectal Neoplasms; Humans; Inositol; Liver Neoplasms; Mice; Phytic Acid | 2021 |
Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice.
Topics: Adenocarcinoma; Animals; Colorectal Neoplasms; Female; Inositol; Liver Neoplasms; Mice; Mice, Inbred | 2016 |
Inflammatory bowel disease: a model of chronic inflammation-induced cancer.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Transformation, Neoplastic; Colorectal Neoplasms; | 2009 |
Effect of phytic acid and inositol on the proliferation and apoptosis of cells derived from colorectal carcinoma.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Inositol; | 2010 |
Inhibition of chronic ulcerative colitis associated adenocarcinoma development in mice by inositol compounds.
Topics: Adenocarcinoma; Animals; Body Weight; Chronic Disease; Colitis, Ulcerative; Colorectal Neoplasms; Fe | 2007 |
Potential of the Akt inhibitor LY294005 to antagonize the efficacy of Cisplatin against HCT116 tumor cells in a DNA mismatch repair-dependent manner.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antineoplastic Agents; Base Pair Mismatch; Car | 2006 |