inositol has been researched along with Colonic Neoplasms in 11 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inositol hexaphosphate (IP6), a widely found natural bioactive substance in grains, effectively inhibits the progression of colorectal cancer (CRC) when used in combination with inositol (INS)." | 8.31 | The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7. ( Chen, Z; Han, Y; Lan, T; Li, H; Ma, X; Song, Y; Tao, M; Wang, C; Wang, H; Xu, Z; Yang, N, 2023) |
| "Inositol hexaphosphate (IP6), a widely found natural bioactive substance in grains, effectively inhibits the progression of colorectal cancer (CRC) when used in combination with inositol (INS)." | 4.31 | The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7. ( Chen, Z; Han, Y; Lan, T; Li, H; Ma, X; Song, Y; Tao, M; Wang, C; Wang, H; Xu, Z; Yang, N, 2023) |
| "A striking anticancer effect of IP6 was demonstrated in different experimental models." | 2.42 | Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic. ( Shamsuddin, AM; Vucenik, I, 2003) |
| "Phytic acid (PA) also acts as a natural antioxidant and may have numerous health benefits." | 1.37 | Green tea, phytic acid, and inositol in combination reduced the incidence of azoxymethane-induced colon tumors in Fisher 344 male rats. ( Davis, S; Khatiwada, J; Verghese, M; Williams, LL, 2011) |
| "Three human colon cancer cell lines were treated with BB-pol: HT-29, HCT-116, and Caco-2." | 1.32 | Anticancerogenic effect of a novel chiroinositol-containing polysaccharide from Bifidobacterium bifidum BGN4. ( Ji, GE; Oh, DK; You, HJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Han, Y | 1 |
| Lan, T | 1 |
| Ma, X | 1 |
| Yang, N | 1 |
| Wang, C | 1 |
| Xu, Z | 1 |
| Chen, Z | 1 |
| Tao, M | 1 |
| Li, H | 1 |
| Wang, H | 1 |
| Song, Y | 1 |
| Kato, J | 1 |
| Shirakami, Y | 1 |
| Mizutani, T | 1 |
| Kubota, M | 1 |
| Sakai, H | 1 |
| Ibuka, T | 1 |
| Shimizu, M | 1 |
| Weinberg, SE | 1 |
| Sun, LY | 1 |
| Yang, AL | 1 |
| Liao, J | 1 |
| Yang, GY | 1 |
| Khatiwada, J | 1 |
| Verghese, M | 1 |
| Davis, S | 1 |
| Williams, LL | 1 |
| Vucenik, I | 1 |
| Shamsuddin, AM | 1 |
| You, HJ | 1 |
| Oh, DK | 1 |
| Ji, GE | 1 |
| Awad, AB | 1 |
| Fink, CS | 1 |
| Horvath, PJ | 1 |
| Moreno, A | 1 |
| Arús, C | 1 |
| Wali, RK | 1 |
| Baum, CL | 1 |
| Bolt, MJ | 1 |
| Brasitus, TA | 1 |
| Sitrin, MD | 1 |
| Kopp, R | 1 |
| Mayer, P | 1 |
| Pfeiffer, A | 1 |
| Galons, JP | 1 |
| Fantini, J | 1 |
| Vion-Dury, J | 1 |
| Cozzone, PJ | 1 |
| Canioni, P | 1 |
2 reviews available for inositol and Colonic Neoplasms
| Article | Year |
|---|---|
Overview of Inositol and Inositol Phosphates on Chemoprevention of Colitis-Induced Carcinogenesis.
Topics: Animals; Colitis; Colonic Neoplasms; Humans; Inositol; Inositol Phosphates | 2020 |
Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Colonic Neoplasms; Disease Mod | 2003 |
9 other studies available for inositol and Colonic Neoplasms
| Article | Year |
|---|---|
The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7.
Topics: Animals; Cell Line, Tumor; Claudins; Colonic Neoplasms; Colorectal Neoplasms; Epithelial-Mesenchymal | 2023 |
Alpha-Glucosidase Inhibitor Voglibose Suppresses Azoxymethane-Induced Colonic Preneoplastic Lesions in Diabetic and Obese Mice.
Topics: Animals; Antioxidants; Azoxymethane; Biomarkers; Biopsy; Cell Proliferation; Colonic Neoplasms; Cyto | 2020 |
Green tea, phytic acid, and inositol in combination reduced the incidence of azoxymethane-induced colon tumors in Fisher 344 male rats.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protoco | 2011 |
Anticancerogenic effect of a novel chiroinositol-containing polysaccharide from Bifidobacterium bifidum BGN4.
Topics: Antineoplastic Agents; Bifidobacterium; Bromodeoxyuridine; Cell Count; Cell Line, Tumor; Cell Prolif | 2004 |
Alteration of membrane fatty acid composition and inositol phosphate metabolism in HT-29 human colon cancer cells.
Topics: Colonic Neoplasms; Fatty Acids; Humans; Inositol; Inositol Phosphates; Membrane Lipids; Phosphatidyl | 1993 |
Quantitative and qualitative characterization of 1H NMR spectra of colon tumors, normal mucosa and their perchloric acid extracts: decreased levels of myo-inositol in tumours can be detected in intact biopsies.
Topics: Biopsy; Colonic Neoplasms; Female; Glutathione; Humans; Inositol; Intestinal Mucosa; Magnetic Resona | 1996 |
1,25-dihydroxyvitamin D3 inhibits Na(+)-H+ exchange by stimulating membrane phosphoinositide turnover and increasing cytosolic calcium in CaCo-2 cells.
Topics: Amiloride; Calcitriol; Carrier Proteins; Cell Line; Cell Membrane; Colonic Neoplasms; Cytosol; Digly | 1992 |
Agonist-induced desensitization of cholinergically stimulated phosphoinositide breakdown is independent of endogenously activated protein kinase C in HT-29 human colon carcinoma cells.
Topics: Carbachol; Colonic Neoplasms; Enzyme Activation; GTP-Binding Proteins; Humans; Hydrolysis; Inositol; | 1990 |
Metabolic changes in undifferentiated and differentiated human colon adenocarcinoma cells studied by multinuclear magnetic resonance spectroscopy.
Topics: Acetates; Adenocarcinoma; Carbon Isotopes; Cell Differentiation; Colonic Neoplasms; Energy Metabolis | 1989 |