inositol has been researched along with Cleft Spine in 8 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Supplementation with myo-inositol during the periconceptional period of pregnancy may ameliorate the recurrence risk of having a fetus affected by a neural tube defect (NTD; e." | 8.02 | Maternal Inositol Status and Neural Tube Defects: A Role for the Human Yolk Sac in Embryonic Inositol Delivery? ( Copp, AJ; D'Souza, SW; Glazier, JD; Greene, NDE, 2021) |
| "Among mouse genetic mutants that develop neural tube defects (NTDs), some respond to folic acid administration during early pregnancy, whereas NTDs in other mutants are not prevented." | 7.71 | D-chiro-inositol is more effective than myo-inositol in preventing folate-resistant mouse neural tube defects. ( Allan, G; Cogram, P; Copp, AJ; Greene, ND; Tesh, J; Tesh, S; Wade, A, 2002) |
| "Inositol is closely related to the occurrence of neural tube defects (NTDs)." | 4.31 | Genetic Effects of ITPK1 Polymorphisms on the Risk of Neural Tube Defects: a Population-Based Study. ( Guan, Z; Li, S; Liang, Y; Wang, J; Wang, X; Yang, A; Zhu, Z, 2023) |
| "Supplementation with myo-inositol during the periconceptional period of pregnancy may ameliorate the recurrence risk of having a fetus affected by a neural tube defect (NTD; e." | 4.02 | Maternal Inositol Status and Neural Tube Defects: A Role for the Human Yolk Sac in Embryonic Inositol Delivery? ( Copp, AJ; D'Souza, SW; Glazier, JD; Greene, NDE, 2021) |
| "Myo-inositol (MI) deficiency is associated with an increased risk for neural tube defects (NTDs), mental disorders and metabolic diseases." | 3.83 | Quantification of plasma myo-inositol using gas chromatography-mass spectrometry. ( Guo, J; Niu, B; Shi, Y; Wang, J; Xu, C; Zhang, F; Zhang, T; Zhong, R, 2016) |
| " In the spina bifida group, amniotic fluid myo-inositol, glucose and zinc concentrations gradually declined throughout pregnancy." | 3.72 | Are myo-inositol, glucose and zinc concentrations in amniotic fluid of fetuses with spina bifida different from controls? ( Groenen, PM; Janssen, FS; Merkus, JM; Steegers-Theunissen, RP; Tuerlings, JH; Wevers, RA, 2003) |
| "Among mouse genetic mutants that develop neural tube defects (NTDs), some respond to folic acid administration during early pregnancy, whereas NTDs in other mutants are not prevented." | 3.71 | D-chiro-inositol is more effective than myo-inositol in preventing folate-resistant mouse neural tube defects. ( Allan, G; Cogram, P; Copp, AJ; Greene, ND; Tesh, J; Tesh, S; Wade, A, 2002) |
| "The association with spina bifida was expressed by the ratio of geometric means and by odds ratios and 95% CI for a cutoff value at the extreme 10th percentile of the control group." | 1.32 | Maternal myo-inositol, glucose, and zinc status is associated with the risk of offspring with spina bifida. ( Franke, B; Groenen, PM; Mariman, EC; Peer, PG; Steegers-Theunissen, RP; Swinkels, DW; Wevers, RA, 2003) |
| "Seventy-six spina bifida triads only were ascertained." | 1.32 | Spina bifida and genetic factors related to myo-inositol, glucose, and zinc. ( Franke, B; Groenen, PM; Klootwijk, R; Mariman, EC; Schijvenaars, MM; Steegers-Theunissen, RP; Straatman, H, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guan, Z | 2 |
| Liang, Y | 1 |
| Zhu, Z | 1 |
| Yang, A | 1 |
| Li, S | 1 |
| Wang, X | 2 |
| Wang, J | 3 |
| D'Souza, SW | 1 |
| Copp, AJ | 2 |
| Greene, NDE | 1 |
| Glazier, JD | 1 |
| Guo, J | 2 |
| Wang, F | 1 |
| Li, G | 1 |
| Xie, Q | 1 |
| Han, X | 1 |
| Niu, B | 2 |
| Zhang, T | 2 |
| Shi, Y | 1 |
| Xu, C | 1 |
| Zhong, R | 1 |
| Zhang, F | 1 |
| Cogram, P | 1 |
| Tesh, S | 1 |
| Tesh, J | 1 |
| Wade, A | 1 |
| Allan, G | 1 |
| Greene, ND | 1 |
| Groenen, PM | 3 |
| Wevers, RA | 2 |
| Janssen, FS | 1 |
| Tuerlings, JH | 1 |
| Merkus, JM | 1 |
| Steegers-Theunissen, RP | 3 |
| Peer, PG | 1 |
| Swinkels, DW | 1 |
| Franke, B | 2 |
| Mariman, EC | 2 |
| Klootwijk, R | 1 |
| Schijvenaars, MM | 1 |
| Straatman, H | 1 |
8 other studies available for inositol and Cleft Spine
| Article | Year |
|---|---|
Genetic Effects of ITPK1 Polymorphisms on the Risk of Neural Tube Defects: a Population-Based Study.
Topics: Case-Control Studies; Female; Genotype; Humans; Inositol; Neural Tube Defects; Polymorphism, Single | 2023 |
Maternal Inositol Status and Neural Tube Defects: A Role for the Human Yolk Sac in Embryonic Inositol Delivery?
Topics: Female; Folic Acid; Humans; Inositol; Neural Tube Defects; Pregnancy; Spinal Dysraphism; Yolk Sac | 2021 |
The maternal ITPK1 gene polymorphism is associated with neural tube defects in a high-risk Chinese population.
Topics: Adult; Asian People; Case-Control Studies; China; Female; Genotype; Humans; Inositol; Inositol Phosp | 2014 |
Quantification of plasma myo-inositol using gas chromatography-mass spectrometry.
Topics: Anencephaly; Female; Gas Chromatography-Mass Spectrometry; Humans; Inositol; Male; Mass Screening; N | 2016 |
D-chiro-inositol is more effective than myo-inositol in preventing folate-resistant mouse neural tube defects.
Topics: Administration, Oral; Animals; Drug Resistance; Embryonic and Fetal Development; Female; Folic Acid; | 2002 |
Are myo-inositol, glucose and zinc concentrations in amniotic fluid of fetuses with spina bifida different from controls?
Topics: Adult; Amniotic Fluid; Female; Gestational Age; Glucose; Humans; Inositol; Maternal Age; Pregnancy; | 2003 |
Maternal myo-inositol, glucose, and zinc status is associated with the risk of offspring with spina bifida.
Topics: Adult; Biomarkers; Blood Glucose; Case-Control Studies; Child, Preschool; Confidence Intervals; Fema | 2003 |
Spina bifida and genetic factors related to myo-inositol, glucose, and zinc.
Topics: Alcohol Drinking; Blood Glucose; Body Mass Index; Case-Control Studies; Child, Preschool; Erythrocyt | 2004 |