inositol has been researched along with Classic Globoid Cell Leukodystrophy in 3 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Krabbe disease (globoid cell leukodystrophy [GLD]) is an autosomal recessive lysosomal disorder affecting the central and peripheral nervous system." | 2.71 | Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease. ( Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Rusch, O; Wilken, B, 2003) |
| "We present a case of infantile onset Krabbe disease with prolonged survival, initial intracranial optic nerves and optic chiasm hypertrophy, and serial changes on cranial magnetic resonance imaging and magnetic resonance spectroscopy." | 1.38 | Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease. ( Bunge, M; Mhanni, AA; Ryner, L; Salman, MS; Udow, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Udow, S | 1 |
| Bunge, M | 1 |
| Ryner, L | 1 |
| Mhanni, AA | 1 |
| Salman, MS | 1 |
| Brockmann, K | 1 |
| Dechent, P | 1 |
| Wilken, B | 1 |
| Rusch, O | 1 |
| Frahm, J | 1 |
| Hanefeld, F | 1 |
| Vanier, MT | 1 |
| Svennerholm, L | 1 |
1 trial available for inositol and Classic Globoid Cell Leukodystrophy
| Article | Year |
|---|---|
Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Child; Child, Preschool; Choline; Creatinine; Dipeptides | 2003 |
2 other studies available for inositol and Classic Globoid Cell Leukodystrophy
| Article | Year |
|---|---|
Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease.
Topics: Anticonvulsants; Aspartic Acid; Brain Chemistry; Choline; Combined Modality Therapy; Creatine; DNA M | 2012 |
Chemical pathology of Krabbe's disease. I. Lipid composition and fatty acid patterns of phosphoglycerides in brain.
Topics: Brain Chemistry; Cerebral Cortex; Cerebrosides; Child, Preschool; Cholesterol; Choline; Ethanolamine | 1974 |