inositol has been researched along with Chronic Progressive Multiple Sclerosis in 5 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Concentrations of glutamate + glutamin (Glx), cholin (Cho), myoinositol (mIns), N-acetyl aspartate (NAA) expressed as ratio with creatine (Cr) and NAA were correlated with markers of disease activity (RIO score), Multiple Sclerosis Severity Scale (MSSS), Depressive-Severity Status Scale and Simple Numerical Fatigue Scale." | 3.85 | Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue. ( Baranovičová, E; Bittšanský, M; Čierny, D; Hnilicová, P; Kantorová, E; Kurča, E; Nosáľ, V; Poláček, H; Sivák, Š; Zeleňák, K, 2017) |
| "To evaluate the mechanisms underlying disease progression in the early phase of PPMS by measuring metabolite concentrations in normal-appearing white matter (NAWM) and cortical gray matter (CGM) and to assess their relationship with clinical outcomes." | 2.71 | Metabolite changes in normal-appearing gray and white matter are linked with disability in early primary progressive multiple sclerosis. ( Chard, DT; Ingle, GT; McLean, MA; Miller, DH; Ramió-Torrentà, L; Sastre-Garriga, J; Thompson, AJ, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kantorová, E | 1 |
| Poláček, H | 1 |
| Bittšanský, M | 1 |
| Baranovičová, E | 1 |
| Hnilicová, P | 1 |
| Čierny, D | 1 |
| Sivák, Š | 1 |
| Nosáľ, V | 1 |
| Zeleňák, K | 1 |
| Kurča, E | 1 |
| Tur, C | 1 |
| Wheeler-Kingshott, CA | 1 |
| Altmann, DR | 1 |
| Miller, DH | 2 |
| Thompson, AJ | 2 |
| Ciccarelli, O | 1 |
| Sastre-Garriga, J | 1 |
| Ingle, GT | 1 |
| Chard, DT | 1 |
| Ramió-Torrentà, L | 1 |
| McLean, MA | 1 |
| Mader, I | 1 |
| Roser, W | 1 |
| Kappos, L | 1 |
| Hagberg, G | 1 |
| Seelig, J | 1 |
| Radue, EW | 1 |
| Steinbrich, W | 1 |
| Pozdniakov, AV | 1 |
| Tiutin, LA | 1 |
| Bisaga, GN | 1 |
| Odinak, MM | 1 |
2 trials available for inositol and Chronic Progressive Multiple Sclerosis
| Article | Year |
|---|---|
Metabolite changes in normal-appearing gray and white matter are linked with disability in early primary progressive multiple sclerosis.
Topics: Adult; Age of Onset; Aged; Aspartic Acid; Biomarkers; Case-Control Studies; Cerebral Cortex; Choline | 2005 |
Serial proton MR spectroscopy of contrast-enhancing multiple sclerosis plaques: absolute metabolic values over 2 years during a clinical pharmacological study.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Follow-Up Studies; Guanidines; Humans; Image | 2000 |
3 other studies available for inositol and Chronic Progressive Multiple Sclerosis
| Article | Year |
|---|---|
Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue.
Topics: Adult; Aging; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depre | 2017 |
Spatial variability and changes of metabolite concentrations in the cortico-spinal tract in multiple sclerosis using coronal CSI.
Topics: Adult; Aged; Choline; Disability Evaluation; Humans; Hydrogen; Inositol; Magnetic Resonance Imaging; | 2014 |
[Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis].
Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Demyelinating Diseases; Female; gamma-Am | 2001 |