inositol has been researched along with Chromosomal Triplication in 3 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "myo-Inositol is elevated in the Down syndrome (DS; trisomy 21) brain and may play a role in mental retardation." | 7.70 | Ts65Dn mouse, a Down syndrome model, exhibits elevated myo-inositol in selected brain regions and peripheral tissues. ( Galdzicki, Z; Rapoport, SI; Shetty, HU; Siarey, RJ; Stoll, J, 2000) |
| "myo-Inositol is elevated in the Down syndrome (DS; trisomy 21) brain and may play a role in mental retardation." | 3.70 | Ts65Dn mouse, a Down syndrome model, exhibits elevated myo-inositol in selected brain regions and peripheral tissues. ( Galdzicki, Z; Rapoport, SI; Shetty, HU; Siarey, RJ; Stoll, J, 2000) |
| "myo-Inositol was found to be selectively elevated in the brain of the trisomy 16 mouse." | 1.29 | Brain accumulation of myo-inositol in the trisomy 16 mouse, an animal model of Down's syndrome. ( Acevedo, LD; Galdzicki, Z; Holloway, HW; Shetty, HU, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shetty, HU | 3 |
| Holloway, HW | 2 |
| Acevedo, LD | 2 |
| Galdzicki, Z | 2 |
| Rapoport, SI | 2 |
| Siarey, RJ | 1 |
| Stoll, J | 1 |
3 other studies available for inositol and Chromosomal Triplication
| Article | Year |
|---|---|
Brain accumulation of myo-inositol in the trisomy 16 mouse, an animal model of Down's syndrome.
Topics: Animals; Brain; Diploidy; Disease Models, Animal; Down Syndrome; Female; Homeostasis; Humans; Inosit | 1996 |
Application of stable isotope tracer combined with mass spectrometric detection for studying myo-inositol uptake by cultured neurons from fetal mouse: effect of trisomy 16.
Topics: Adult; Animals; Cells, Cultured; Diploidy; Down Syndrome; Female; Gas Chromatography-Mass Spectromet | 1997 |
Ts65Dn mouse, a Down syndrome model, exhibits elevated myo-inositol in selected brain regions and peripheral tissues.
Topics: Animals; Brain; Brain Stem; Cerebellum; Disease Models, Animal; Down Syndrome; Female; Frontal Lobe; | 2000 |