inositol has been researched along with Chemical Dependence in 8 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of pilocarpine or physostigmine to rats treated with lithium chloride produced sustained limbic seizures, widespread brain damage, and increased concentrations of D-myo-inositol-1-phosphate (a metabolite of the phosphoinositides, lipids involved in membrane receptor function) in the brain." | 7.66 | Systemic cholinergic agents induce seizures and brain damage in lithium-treated rats. ( Honchar, MP; Olney, JW; Sherman, WR, 1983) |
| "Administration of pilocarpine or physostigmine to rats treated with lithium chloride produced sustained limbic seizures, widespread brain damage, and increased concentrations of D-myo-inositol-1-phosphate (a metabolite of the phosphoinositides, lipids involved in membrane receptor function) in the brain." | 3.66 | Systemic cholinergic agents induce seizures and brain damage in lithium-treated rats. ( Honchar, MP; Olney, JW; Sherman, WR, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Smucny, J | 1 |
| Maddock, RJ | 1 |
| Howells, FM | 1 |
| Uhlmann, A | 1 |
| Temmingh, H | 1 |
| Sinclair, H | 1 |
| Meintjes, E | 1 |
| Wilson, D | 1 |
| Stein, DJ | 1 |
| Cowan, RL | 2 |
| Joers, JM | 1 |
| Dietrich, MS | 1 |
| Licata, SC | 1 |
| Renshaw, PF | 2 |
| Parikh, SV | 1 |
| LeBlanc, SR | 1 |
| Ovanessian, MM | 1 |
| Bolo, NR | 1 |
| Dietrich, M | 1 |
| Haga, E | 1 |
| Lukas, SE | 1 |
| Honchar, MP | 1 |
| Olney, JW | 1 |
| Sherman, WR | 1 |
| Chang, L | 1 |
| Ernst, T | 1 |
| Grob, CS | 1 |
| Poland, RE | 1 |
2 reviews available for inositol and Chemical Dependence
| Article | Year |
|---|---|
Spectroscopic meta-analyses reveal novel metabolite profiles across methamphetamine and cocaine substance use disorder.
Topics: Brain; Choline; Creatine; Glutamic Acid; Humans; Inositol; Magnetic Resonance Spectroscopy; Methamph | 2023 |
Neurochemistry of drug action: insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction.
Topics: Alcoholism; Animals; Appetite Stimulants; Aspartic Acid; Brain; Choline; Cocaine; Creatine; Glutamic | 2010 |
6 other studies available for inositol and Chemical Dependence
| Article | Year |
|---|---|
(1)H-magnetic resonance spectroscopy ((1)H-MRS) in methamphetamine dependence and methamphetamine induced psychosis.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Glutamine; Humans; Inositol; Mag | 2014 |
N-acetylaspartate (NAA) correlates inversely with cannabis use in a frontal language processing region of neocortex in MDMA (Ecstasy) polydrug users: a 3 T magnetic resonance spectroscopy study.
Topics: Amphetamine-Related Disorders; Aspartic Acid; Biomarkers; Brain Chemistry; Female; Hallucinogens; Hu | 2009 |
Advancing bipolar disorder: key lessons from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
Topics: Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Anxiety Disorders; | 2010 |
Occipital cortical proton MRS at 4 Tesla in human moderate MDMA polydrug users.
Topics: Adolescent; Adult; Amphetamines; Analgesics, Opioid; Aspartic Acid; Cannabis; Cocaine; Female; Hallu | 2007 |
Systemic cholinergic agents induce seizures and brain damage in lithium-treated rats.
Topics: Animals; Atropine; Brain Chemistry; Chlorides; Drug Interactions; Humans; Inositol; Inositol Phospha | 1983 |
Cerebral (1)H MRS alterations in recreational 3, 4-methylenedioxymethamphetamine (MDMA, "ecstasy") users.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; Ha | 1999 |