Page last updated: 2024-10-19

inositol and Chagas Disease

inositol has been researched along with Chagas Disease in 2 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.

Research Excerpts

ExcerptRelevanceReference
"Chagas' disease is a debilitating and often fatal disease caused by the protozoan parasite Trypanosoma cruzi."6.41Inositol metabolism in Trypanosoma cruzi: potential target for chemotherapy against Chagas' disease. ( Einicker-Lamas, M; Oliveira, MM, 2000)
"Chagas' disease is a debilitating and often fatal disease caused by the protozoan parasite Trypanosoma cruzi."2.41Inositol metabolism in Trypanosoma cruzi: potential target for chemotherapy against Chagas' disease. ( Einicker-Lamas, M; Oliveira, MM, 2000)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Dos Santos, NSA1
Estevez-Castro, CF1
Macedo, JP1
Chame, DF1
Castro-Gomes, T1
Santos-Cardoso, M1
Burle-Caldas, GA1
Covington, CN1
Steel, PG1
Smith, TK1
Denny, PW1
Teixeira, SMR1
Oliveira, MM1
Einicker-Lamas, M1

Reviews

1 review available for inositol and Chagas Disease

ArticleYear
Inositol metabolism in Trypanosoma cruzi: potential target for chemotherapy against Chagas' disease.
    Anais da Academia Brasileira de Ciencias, 2000, Volume: 72, Issue:3

    Topics: Animals; Chagas Disease; Humans; Inositol; Lipid Metabolism; Trypanosoma cruzi

2000

Other Studies

1 other study available for inositol and Chagas Disease

ArticleYear
Disruption of the inositol phosphorylceramide synthase gene affects Trypanosoma cruzi differentiation and infection capacity.
    PLoS neglected tropical diseases, 2023, Volume: 17, Issue:9

    Topics: Animals; Cell Differentiation; Chagas Disease; Inositol; Leishmania major; Mammals; Mice; Trypanosom

2023