inositol has been researched along with Cerebral Ischemia in 12 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Roflumilast (Roflu) is an FDA-approved PDE4 inhibitor for the treatment of chronic obstructive pulmonary disease." | 5.62 | Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway. ( Cai, N; Li, M; Li, X; Liu, L; Qin, Y; Wang, H; Xu, B; Xu, J, 2021) |
| " First, in patients with cerebral infarctions, increased concentrations of lactate were found in the majority of patients, and N-acetyl aspartate (NAA) was reduced to a significantly greater extent than choline (Cho) or creatine (Cre)." | 3.68 | Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities. ( Calabrese, G; Deicken, R; Fein, G; Fisher, SN; Hetherington, HP; Sappey-Marinier, D; Van Dyke, C; Weiner, MW, 1992) |
| "Roflumilast (Roflu) is an FDA-approved PDE4 inhibitor for the treatment of chronic obstructive pulmonary disease." | 1.62 | Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway. ( Cai, N; Li, M; Li, X; Liu, L; Qin, Y; Wang, H; Xu, B; Xu, J, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, B | 1 |
| Xu, J | 1 |
| Cai, N | 1 |
| Li, M | 1 |
| Liu, L | 1 |
| Qin, Y | 1 |
| Li, X | 1 |
| Wang, H | 1 |
| Villalba, H | 1 |
| Shah, K | 1 |
| Albekairi, TH | 1 |
| Sifat, AE | 1 |
| Vaidya, B | 1 |
| Abbruscato, TJ | 1 |
| Jiménez-Xarrié, E | 1 |
| Davila, M | 1 |
| Candiota, AP | 1 |
| Delgado-Mederos, R | 1 |
| Ortega-Martorell, S | 1 |
| Julià-Sapé, M | 1 |
| Arús, C | 1 |
| Martí-Fàbregas, J | 1 |
| Shiino, A | 1 |
| Watanabe, T | 1 |
| Shirakashi, Y | 1 |
| Kotani, E | 1 |
| Yoshimura, M | 1 |
| Morikawa, S | 1 |
| Inubushi, T | 1 |
| Akiguchi, I | 1 |
| Tzeng, HF | 1 |
| Chen, JY | 1 |
| Huang, SW | 1 |
| Wang, YJ | 1 |
| Yang, CS | 1 |
| Nitkunan, A | 1 |
| Charlton, RA | 1 |
| McIntyre, DJ | 1 |
| Barrick, TR | 1 |
| Howe, FA | 1 |
| Markus, HS | 1 |
| Cucinotta, D | 1 |
| Silvestrini, C | 1 |
| Mancini, M | 1 |
| Maini, C | 1 |
| Passeri, M | 1 |
| Wick, M | 2 |
| Nagatomo, Y | 1 |
| Prielmeier, F | 1 |
| Frahm, J | 2 |
| Fujimori, H | 1 |
| Michaelis, T | 1 |
| Sun, GY | 2 |
| Lu, FL | 1 |
| Lin, SE | 1 |
| Ko, MR | 1 |
| Sappey-Marinier, D | 1 |
| Calabrese, G | 1 |
| Hetherington, HP | 1 |
| Fisher, SN | 1 |
| Deicken, R | 1 |
| Van Dyke, C | 1 |
| Fein, G | 1 |
| Weiner, MW | 1 |
| Lin, TN | 1 |
| Premkumar, N | 1 |
| MacQuarrie, RA | 1 |
| Carter, SR | 1 |
2 trials available for inositol and Cerebral Ischemia
| Article | Year |
|---|---|
The profile of hippocampal metabolites differs between Alzheimer's disease and subcortical ischemic vascular dementia, as measured by proton magnetic resonance spectroscopy.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Brain Ischemia; Dementia, Vascular; Female; | 2012 |
[Experience with the medical treatment of chronic cerebrovascular insufficiency: bamethan and inositol nicotinate versus placebo].
Topics: Aged; Brain Ischemia; Chronic Disease; Clinical Trials as Topic; Ethanolamines; Female; Humans; Inos | 1981 |
10 other studies available for inositol and Cerebral Ischemia
| Article | Year |
|---|---|
Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway.
Topics: Aminopyridines; Animals; Apoptosis; Benzamides; Brain Ischemia; Cyclopropanes; Endoribonucleases; Gl | 2021 |
Potential role of myo-inositol to improve ischemic stroke outcome in diabetic mouse.
Topics: Animals; Brain; Brain Ischemia; Cell Hypoxia; Diabetes Mellitus, Experimental; Glucose; Inositol; Ma | 2018 |
Brain metabolic pattern analysis using a magnetic resonance spectra classification software in experimental stroke.
Topics: Animals; Brain; Brain Ischemia; Creatine; Image Processing, Computer-Assisted; Inositol; Lactic Acid | 2017 |
Simultaneous determination of myo-inositol and scyllo-inositol by MEKC as a rapid monitoring tool for inositol levels.
Topics: Anhydrides; Animals; Brain Ischemia; Chromatography, Micellar Electrokinetic Capillary; Glucose; Gly | 2007 |
Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease.
Topics: Aged; Aspartic Acid; Brain Diseases; Brain Ischemia; Case-Control Studies; Cerebrovascular Circulati | 2008 |
Alteration of intracellular metabolite diffusion in rat brain in vivo during ischemia and reperfusion.
Topics: Animals; Aspartic Acid; Body Water; Brain; Brain Ischemia; Choline; Creatine; Diffusion; Inositol; I | 1995 |
Proton T2 relaxation of cerebral metabolites during transient global ischemia in rat brain.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Image Processing, Computer-Assiste | 1998 |
Decapitation ischemia-induced release of free fatty acids in mouse brain. Relationship with diacylglycerols and lysophospholipids.
Topics: Animals; Brain Chemistry; Brain Ischemia; Choline; Diglycerides; Fatty Acids, Nonesterified; Female; | 1992 |
Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Ischemia; Cerebral Infarction; | 1992 |
Decapitation-induced changes in inositol phosphates in rat brain.
Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Decerebrate State; Inositol; Inositol Phosphates; K | 1990 |