Page last updated: 2024-10-19

inositol and Cerebellar Ataxia

inositol has been researched along with Cerebellar Ataxia in 5 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)

Research Excerpts

ExcerptRelevanceReference
"In 2014, we first described novel autoantibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1-IgG/anti-Sj) in patients with autoimmune cerebellar ataxia (ACA) in this journal."9.22Inositol 1,4,5-trisphosphate receptor type 1 autoantibody (ITPR1-IgG/anti-Sj)-associated autoimmune cerebellar ataxia, encephalitis and peripheral neuropathy: review of the literature. ( Bräuninger, S; Chung, HY; Geis, C; Haas, J; Jarius, S; Komorowski, L; Roth, C; Wildemann, B, 2022)
"In 2014, we first described novel autoantibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1-IgG/anti-Sj) in patients with autoimmune cerebellar ataxia (ACA) in this journal."5.22Inositol 1,4,5-trisphosphate receptor type 1 autoantibody (ITPR1-IgG/anti-Sj)-associated autoimmune cerebellar ataxia, encephalitis and peripheral neuropathy: review of the literature. ( Bräuninger, S; Chung, HY; Geis, C; Haas, J; Jarius, S; Komorowski, L; Roth, C; Wildemann, B, 2022)
"Five patients with undefined ataxia had a substantial decrease of pontine or cerebellar NAA/Cr ratio when compared with that of the control subjects."1.31Proton MR spectroscopy of the cerebellum and pons in patients with degenerative ataxia. ( Cosottini, M; Ferlini, A; Lolli, F; Macucci, M; Mascalchi, M; Plasmati, R; Salvi, F; Tassinari, CA; Tessa, C; Tosetti, M; Villari, N, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Jarius, S1
Bräuninger, S1
Chung, HY1
Geis, C1
Haas, J1
Komorowski, L1
Wildemann, B1
Roth, C1
Ridley, CM1
Thur, KE1
Shanahan, J1
Thillaiappan, NB1
Shen, A1
Uhl, K1
Walden, CM1
Rahim, AA1
Waddington, SN1
Platt, FM1
van der Spoel, AC1
Moghadam, KK1
Pizza, F1
Tonon, C1
Lodi, R1
Carelli, V1
Poli, F1
Franceschini, C1
Barboni, P1
Seri, M1
Ferrari, S1
La Morgia, C1
Testa, C1
Cornelio, F1
Liguori, R1
Winkelmann, J1
Lin, L1
Mignot, E1
Plazzi, G1
Wilkinson, ID1
Hadjivassiliou, M1
Dickson, JM1
Wallis, L1
Grünewald, RA1
Coley, SC1
Widjaja, E1
Griffiths, PD1
Mascalchi, M1
Cosottini, M1
Lolli, F1
Salvi, F1
Tessa, C1
Macucci, M1
Tosetti, M1
Plasmati, R1
Ferlini, A1
Tassinari, CA1
Villari, N1

Reviews

1 review available for inositol and Cerebellar Ataxia

ArticleYear
Inositol 1,4,5-trisphosphate receptor type 1 autoantibody (ITPR1-IgG/anti-Sj)-associated autoimmune cerebellar ataxia, encephalitis and peripheral neuropathy: review of the literature.
    Journal of neuroinflammation, 2022, Jul-30, Volume: 19, Issue:1

    Topics: Autoantibodies; Carrier Proteins; Cerebellar Ataxia; Encephalitis; Female; Humans; Immunoglobulin G;

2022

Other Studies

4 other studies available for inositol and Cerebellar Ataxia

ArticleYear
β-Glucosidase 2 (GBA2) activity and imino sugar pharmacology.
    The Journal of biological chemistry, 2013, Sep-06, Volume: 288, Issue:36

    Topics: 1-Deoxynojirimycin; Animals; beta-Glucosidase; Cell Line, Tumor; Cerebellar Ataxia; Chlorocebus aeth

2013
Polysomnographic and neurometabolic features may mark preclinical autosomal dominant cerebellar ataxia, deafness, and narcolepsy due to a mutation in the DNA (cytosine-5-)-methyltransferase gene, DNMT1.
    Sleep medicine, 2014, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asymptomatic Diseases; Brain; Cerebellar Ataxia; Cerebel

2014
Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia.
    Journal of neurology, neurosurgery, and psychiatry, 2005, Volume: 76, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Celiac Disease; Cerebellar Ataxia; Cerebellar Nuclei;

2005
Proton MR spectroscopy of the cerebellum and pons in patients with degenerative ataxia.
    Radiology, 2002, Volume: 223, Issue:2

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Aspartic Acid; Ataxia; Case-Control Studies; Cerebell

2002