inositol has been researched along with Cell Transformation, Neoplastic in 17 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A striking anticancer action of IP(6) was demonstrated in different experimental models." | 2.43 | Protection against cancer by dietary IP6 and inositol. ( Shamsuddin, AM; Vucenik, I, 2006) |
| "Chronic inflammation is a well-recognized risk factor for the development of human cancer." | 1.35 | Inflammatory bowel disease: a model of chronic inflammation-induced cancer. ( Liao, J; Taboada, S; Yang, GY, 2009) |
| " Down-regulation of protein kinase C by chronic administration of phorbol ester did not block the mitogenic effect of p60v-src." | 1.28 | The oncogenic protein p60v-src has competence activity but does not activate phosphatidylinositol turnover or protein kinase C in Balb/c 3T3 cells. ( Burstein, E; Gaut, J; Han, JW; Macara, IG; Sadowski, H; Young, D, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Backshall, A | 1 |
| Alferez, D | 1 |
| Teichert, F | 1 |
| Wilson, ID | 1 |
| Wilkinson, RW | 1 |
| Goodlad, RA | 1 |
| Keun, HC | 2 |
| Yang, GY | 1 |
| Taboada, S | 1 |
| Liao, J | 1 |
| Kassie, F | 1 |
| Melkamu, T | 1 |
| Endalew, A | 1 |
| Upadhyaya, P | 2 |
| Luo, X | 1 |
| Hecht, SS | 2 |
| Yakoub, D | 1 |
| Goldin, R | 1 |
| Hanna, GB | 1 |
| Wang, M | 1 |
| Bliss, RL | 1 |
| McIntee, EJ | 1 |
| Kenney, PM | 1 |
| Berrie, CP | 1 |
| Dragani, LK | 1 |
| van der Kaay, J | 1 |
| Iurisci, C | 1 |
| Brancaccio, A | 1 |
| Rotilio, D | 1 |
| Corda, D | 1 |
| Vucenik, I | 1 |
| Shamsuddin, AM | 1 |
| Bunce, CM | 1 |
| French, PJ | 1 |
| Allen, P | 1 |
| Mountford, JC | 1 |
| Moor, B | 1 |
| Greaves, MF | 1 |
| Michell, RH | 1 |
| Brown, G | 1 |
| Hervagault, JF | 1 |
| Ortoleva, PJ | 1 |
| Ross, J | 1 |
| Han, JW | 1 |
| Gaut, J | 1 |
| Burstein, E | 1 |
| Sadowski, H | 1 |
| Young, D | 1 |
| Macara, IG | 1 |
| Alonso, T | 2 |
| Srivastava, S | 1 |
| Santos, E | 2 |
| Kubota, Y | 1 |
| Inoue, H | 1 |
| Yoshioka, T | 1 |
| Jackowski, S | 1 |
| Rettenmier, CW | 1 |
| Sherr, CJ | 1 |
| Rock, CO | 1 |
| Morgan, RO | 1 |
| Marvizon, JC | 1 |
| Zarbl, H | 1 |
| Benjamin, CW | 1 |
| Connor, JA | 1 |
| Tarpley, WG | 1 |
| Gorman, RR | 1 |
| Koch, MA | 1 |
| Diringer, H | 1 |
| Bather, R | 1 |
| Yang, J | 1 |
1 review available for inositol and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Protection against cancer by dietary IP6 and inositol.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic | 2006 |
16 other studies available for inositol and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Detection of metabolic alterations in non-tumor gastrointestinal tissue of the Apc(Min/+) mouse by (1)H MAS NMR spectroscopy.
Topics: Adenomatous Polyposis Coli Protein; Animals; Cell Transformation, Neoplastic; Colon; Dimethylamines; | 2009 |
Inflammatory bowel disease: a model of chronic inflammation-induced cancer.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Transformation, Neoplastic; Colorectal Neoplasms; | 2009 |
Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Be | 2010 |
Metabolic profiling detects field effects in nondysplastic tissue from esophageal cancer patients.
Topics: Adenocarcinoma; Barrett Esophagus; Cell Transformation, Neoplastic; Diagnosis, Differential; Esophag | 2010 |
Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination.
Topics: Animals; Antineoplastic Agents; Carcinogenicity Tests; Cell Transformation, Neoplastic; Cysteine; Di | 2002 |
Maintenance of PtdIns45P2 pools under limiting inositol conditions, as assessed by liquid chromatography-tandem mass spectrometry and PtdIns45P2 mass evaluation in Ras-transformed cells.
Topics: Cell Transformation, Neoplastic; Chromatography, Liquid; Genes, ras; Humans; Inositol; Inositol Phos | 2002 |
Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts.
Topics: Animals; B-Lymphocytes; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation | 1993 |
A plausible model for reversal of neoplastic transformations in plants based on multiple steady states.
Topics: Calcium; Cell Transformation, Neoplastic; Inositol; Inositol Phosphates; Models, Biological; Neoplas | 1991 |
The oncogenic protein p60v-src has competence activity but does not activate phosphatidylinositol turnover or protein kinase C in Balb/c 3T3 cells.
Topics: Animals; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Enz | 1990 |
Alterations of G-protein coupling function in phosphoinositide signaling pathways of cells transformed by ras and other membrane-associated and cytoplasmic oncogenes.
Topics: Aluminum; Aluminum Compounds; Animals; Bradykinin; Calcium; Cell Line; Cell Membrane; Cell Transform | 1990 |
Increased labelling of polyphosphoinositide in chemically transformed cell line C3H10T1/2 CL8.
Topics: Animals; Biological Transport; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Inositol | 1986 |
A guanine nucleotide-dependent phosphatidylinositol 4,5-diphosphate phospholipase C in cells transformed by the v-fms and v-fes oncogenes.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Calcium; Cell Line; Cell Membrane; Cell Transformation, Ne | 1986 |
Malignant transformation by ras and other oncogenes produces common alterations in inositol phospholipid signaling pathways.
Topics: Animals; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Genes, | 1988 |
NIH-3T3 cells transformed by the EJ-ras oncogene exhibit reduced platelet-derived growth factor-mediated Ca2+ mobilization.
Topics: Animals; Calcium; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Genes, r | 1988 |
Isolation of cyclic inositol-1,2-phosphate from mammalian cells and a probable function of phosphatidylinositol turnover.
Topics: Cell Line; Cell Transformation, Neoplastic; Chromatography, Paper; Cyclic P-Oxides; Glycerol; Inosit | 1974 |
Myo-inositol influences release and inactivation of murine sarcoma virus from desiccated transformed mouse embryo cells.
Topics: Animals; Cell Transformation, Neoplastic; Embryo, Mammalian; Freeze Drying; Humidity; Inositol; Mice | 1969 |