inositol has been researched along with Cardiomegaly in 3 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac hypertrophy was produced in Sprague-Dawley rats by abdominal aortic constriction and treated with lisinopril (15 mg/kg) or pinitol (5, 10, and 20 mg/kg)." | 1.62 | Elucidation of the mechanism of action of pinitol against pressure overload-induced cardiac hypertrophy and fibrosis in an animal model of aortic stenosis. ( Feng, Z; Hu, X; L V, X; Zhu, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Tappia, PS | 1 |
| Ramjiawan, B | 1 |
| Dhalla, NS | 1 |
| Hu, X | 1 |
| Zhu, Y | 1 |
| L V, X | 1 |
| Feng, Z | 1 |
| Jaeger, JJ | 1 |
| McGrath, JJ | 1 |
1 review available for inositol and Cardiomegaly
| Article | Year |
|---|---|
Role of phospholipase C in catecholamine-induced increase in myocardial protein synthesis.
Topics: Adenylyl Cyclases; Cardiomegaly; Catecholamines; GTP-Binding Proteins; Humans; Inositol; Isoenzymes; | 2022 |
2 other studies available for inositol and Cardiomegaly
| Article | Year |
|---|---|
Elucidation of the mechanism of action of pinitol against pressure overload-induced cardiac hypertrophy and fibrosis in an animal model of aortic stenosis.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Gene Expression Profiling; Heart Function Tests; Inos | 2021 |
Hematologic and biochemical effects of simulated high altitude on the Japanese quail.
Topics: Altitude; Animals; Blood Glucose; Blood Volume; Body Weight; Carbohydrate Metabolism; Cardiomegaly; | 1974 |