Page last updated: 2024-10-19

inositol and Cardiac Hypertrophy

inositol has been researched along with Cardiac Hypertrophy in 3 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
"Cardiac hypertrophy was produced in Sprague-Dawley rats by abdominal aortic constriction and treated with lisinopril (15 mg/kg) or pinitol (5, 10, and 20 mg/kg)."1.62Elucidation of the mechanism of action of pinitol against pressure overload-induced cardiac hypertrophy and fibrosis in an animal model of aortic stenosis. ( Feng, Z; Hu, X; L V, X; Zhu, Y, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Tappia, PS1
Ramjiawan, B1
Dhalla, NS1
Hu, X1
Zhu, Y1
L V, X1
Feng, Z1
Jaeger, JJ1
McGrath, JJ1

Reviews

1 review available for inositol and Cardiac Hypertrophy

ArticleYear
Role of phospholipase C in catecholamine-induced increase in myocardial protein synthesis.
    Canadian journal of physiology and pharmacology, 2022, Oct-01, Volume: 100, Issue:10

    Topics: Adenylyl Cyclases; Cardiomegaly; Catecholamines; GTP-Binding Proteins; Humans; Inositol; Isoenzymes;

2022

Other Studies

2 other studies available for inositol and Cardiac Hypertrophy

ArticleYear
Elucidation of the mechanism of action of pinitol against pressure overload-induced cardiac hypertrophy and fibrosis in an animal model of aortic stenosis.
    Bioscience, biotechnology, and biochemistry, 2021, Feb-24, Volume: 85, Issue:3

    Topics: Animals; Cardiomegaly; Disease Models, Animal; Gene Expression Profiling; Heart Function Tests; Inos

2021
Hematologic and biochemical effects of simulated high altitude on the Japanese quail.
    Journal of applied physiology, 1974, Volume: 37, Issue:3

    Topics: Altitude; Animals; Blood Glucose; Blood Volume; Body Weight; Carbohydrate Metabolism; Cardiomegaly;

1974