Page last updated: 2024-10-19

inositol and Cardiac Failure

inositol has been researched along with Cardiac Failure in 12 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
" Reduced myocardial levels of myo-inositol in the myocardium of MI animals point to altered phospholipid metabolism and membrane receptor function in heart failure."3.91Metabolomic analysis of serum and myocardium in compensated heart failure after myocardial infarction. ( Barupal, DK; Fan, S; Hammond, HK; Ichikawa, Y; McKirnan, MD; Patel, HH; Roth, DM; Zemljic-Harpf, AE; Zhang, Z, 2019)
"Since 1) dilated cardiomyopathy (DCM) causes chronic heart failure (CHF), and 2) augmentation of neurohumoral factors such as angiotensin II impairs glucose metabolism, we examined the rate of abnormal glucose metabolism in patients having both DCM and CHF and whether correction of the impairment of glucose metabolism would improve the pathophysiology of CHF in DCM patients."1.33Abnormal glucose tolerance contributes to the progression of chronic heart failure in patients with dilated cardiomyopathy. ( Asakura, M; Asanuma, H; Hashimura, K; Kanzaki, H; Kim, J; Kitakaze, M; Kokubo, Y; Komamura, K; Nakatani, S; Tomoike, H, 2006)
"The creatine level was independently correlated with half-recovery time and duration of heart failure symptoms in PWM (r = -0."1.30Cerebral metabolic abnormalities in congestive heart failure detected by proton magnetic resonance spectroscopy. ( Hong, MK; Kim, JJ; Kim, ST; Lee, CW; Lee, JH; Lim, TH; Park, SJ; Park, SW, 1999)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's6 (50.00)29.6817
2010's3 (25.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Ejiri, K2
Miyoshi, T2
Kihara, H2
Hata, Y2
Nagano, T2
Takaishi, A2
Toda, H2
Namba, S1
Nakamura, Y2
Akagi, S2
Sakuragi, S2
Minagawa, T2
Kawai, Y2
Nishii, N2
Fuke, S2
Yoshikawa, M2
Nakamura, K2
Ito, H2
Nanba, S1
McKirnan, MD1
Ichikawa, Y1
Zhang, Z1
Zemljic-Harpf, AE1
Fan, S1
Barupal, DK1
Patel, HH1
Hammond, HK1
Roth, DM1
Woo, MA1
Yadav, SK1
Macey, PM1
Fonarow, GC1
Harper, RM1
Kumar, R1
Diercks, DB1
Owen, K1
Tolstikov, V1
Sutter, M1
Lee, CW3
Lee, JH3
Yang, HS2
Lim, KH1
Ahn, JM1
Hong, MK3
Park, SW3
Park, SJ3
Song, MG1
Kim, JJ3
Liao, Y1
Takashima, S1
Zhao, H1
Asano, Y1
Shintani, Y1
Minamino, T1
Kim, J2
Fujita, M1
Hori, M1
Kitakaze, M2
Nakatani, S1
Hashimura, K1
Komamura, K1
Kanzaki, H1
Asakura, M1
Asanuma, H1
Kokubo, Y1
Tomoike, H1
Kim, ST1
Lim, TH2
Nagai, Y1
Hayakawa, T1
Abe, T1
Nomura, G1
Malloy, CR1
Song, JK1

Trials

3 trials available for inositol and Cardiac Failure

ArticleYear
Effects of luseogliflozin and voglibose on high-risk lipid profiles and inflammatory markers in diabetes patients with heart failure.
    Scientific reports, 2022, 09-14, Volume: 12, Issue:1

    Topics: Adiponectin; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Diabetes Mellitus, Type 2; Glucose; H

2022
Effect of Luseogliflozin on Heart Failure With Preserved Ejection Fraction in Patients With Diabetes Mellitus.
    Journal of the American Heart Association, 2020, 08-18, Volume: 9, Issue:16

    Topics: Aged; Biomarkers; Diabetes Mellitus, Type 2; Drug Administration Schedule; Female; Heart Failure; Hu

2020
Prognostic significance of cerebral metabolic abnormalities in patients with congestive heart failure.
    Circulation, 2001, Jun-12, Volume: 103, Issue:23

    Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Creatine; Female; Follow-Up Studies

2001

Other Studies

9 other studies available for inositol and Cardiac Failure

ArticleYear
Metabolomic analysis of serum and myocardium in compensated heart failure after myocardial infarction.
    Life sciences, 2019, Mar-15, Volume: 221

    Topics: Animals; Echocardiography; Female; Heart Failure; Heart Ventricles; Inosine; Inositol; Male; Metabol

2019
Brain metabolites in autonomic regulatory insular sites in heart failure.
    Journal of the neurological sciences, 2014, Nov-15, Volume: 346, Issue:1-2

    Topics: Adult; Autonomic Nervous System; Cerebral Cortex; Choline; Creatine; Female; Heart Failure; Humans;

2014
Urinary metabolomic analysis for the identification of renal injury in patients with acute heart failure.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2012, Volume: 19, Issue:1

    Topics: Aged; Biomarkers; Creatinine; Discriminant Analysis; Female; Gas Chromatography-Mass Spectrometry; G

2012
Effects of heart transplantation on cerebral metabolic abnormalities in patients with congestive heart failure.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2006, Volume: 25, Issue:3

    Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Heart Failure; Heart Transplantation; Humans

2006
Control of plasma glucose with alpha-glucosidase inhibitor attenuates oxidative stress and slows the progression of heart failure in mice.
    Cardiovascular research, 2006, Apr-01, Volume: 70, Issue:1

    Topics: Acetophenones; Animals; Blotting, Western; Body Weight; Cells, Cultured; Disease Progression; Echoca

2006
Abnormal glucose tolerance contributes to the progression of chronic heart failure in patients with dilated cardiomyopathy.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:10

    Topics: Cardiomyopathy, Dilated; Chronic Disease; Disease Progression; Echocardiography; Female; Glucose Int

2006
Cerebral metabolic abnormalities in congestive heart failure detected by proton magnetic resonance spectroscopy.
    Journal of the American College of Cardiology, 1999, Volume: 33, Issue:5

    Topics: Adult; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Echocardiography, Doppler; Exercise Test;

1999
Are there different effects of acarbose and voglibose on serum levels of digoxin in a diabetic patient with congestive heart failure?
    Diabetes care, 2000, Volume: 23, Issue:11

    Topics: Acarbose; Aged; Aged, 80 and over; Cardiotonic Agents; Diabetes Mellitus, Type 2; Digoxin; Drug Inte

2000
Correlation of cerebral metabolites with clinical outcome among patients with severe congestive heart failure.
    Circulation, 2001, Jun-12, Volume: 103, Issue:23

    Topics: Aspartic Acid; Brain; Choline; Cognition Disorders; Creatine; Disease Progression; Heart Failure; Hu

2001