inositol has been researched along with Brain Ischemia in 12 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Roflumilast (Roflu) is an FDA-approved PDE4 inhibitor for the treatment of chronic obstructive pulmonary disease." | 5.62 | Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway. ( Cai, N; Li, M; Li, X; Liu, L; Qin, Y; Wang, H; Xu, B; Xu, J, 2021) |
| " First, in patients with cerebral infarctions, increased concentrations of lactate were found in the majority of patients, and N-acetyl aspartate (NAA) was reduced to a significantly greater extent than choline (Cho) or creatine (Cre)." | 3.68 | Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities. ( Calabrese, G; Deicken, R; Fein, G; Fisher, SN; Hetherington, HP; Sappey-Marinier, D; Van Dyke, C; Weiner, MW, 1992) |
| "Roflumilast (Roflu) is an FDA-approved PDE4 inhibitor for the treatment of chronic obstructive pulmonary disease." | 1.62 | Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway. ( Cai, N; Li, M; Li, X; Liu, L; Qin, Y; Wang, H; Xu, B; Xu, J, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, B | 1 |
| Xu, J | 1 |
| Cai, N | 1 |
| Li, M | 1 |
| Liu, L | 1 |
| Qin, Y | 1 |
| Li, X | 1 |
| Wang, H | 1 |
| Villalba, H | 1 |
| Shah, K | 1 |
| Albekairi, TH | 1 |
| Sifat, AE | 1 |
| Vaidya, B | 1 |
| Abbruscato, TJ | 1 |
| Jiménez-Xarrié, E | 1 |
| Davila, M | 1 |
| Candiota, AP | 1 |
| Delgado-Mederos, R | 1 |
| Ortega-Martorell, S | 1 |
| Julià-Sapé, M | 1 |
| Arús, C | 1 |
| Martí-Fàbregas, J | 1 |
| Shiino, A | 1 |
| Watanabe, T | 1 |
| Shirakashi, Y | 1 |
| Kotani, E | 1 |
| Yoshimura, M | 1 |
| Morikawa, S | 1 |
| Inubushi, T | 1 |
| Akiguchi, I | 1 |
| Tzeng, HF | 1 |
| Chen, JY | 1 |
| Huang, SW | 1 |
| Wang, YJ | 1 |
| Yang, CS | 1 |
| Nitkunan, A | 1 |
| Charlton, RA | 1 |
| McIntyre, DJ | 1 |
| Barrick, TR | 1 |
| Howe, FA | 1 |
| Markus, HS | 1 |
| Cucinotta, D | 1 |
| Silvestrini, C | 1 |
| Mancini, M | 1 |
| Maini, C | 1 |
| Passeri, M | 1 |
| Wick, M | 2 |
| Nagatomo, Y | 1 |
| Prielmeier, F | 1 |
| Frahm, J | 2 |
| Fujimori, H | 1 |
| Michaelis, T | 1 |
| Sun, GY | 2 |
| Lu, FL | 1 |
| Lin, SE | 1 |
| Ko, MR | 1 |
| Sappey-Marinier, D | 1 |
| Calabrese, G | 1 |
| Hetherington, HP | 1 |
| Fisher, SN | 1 |
| Deicken, R | 1 |
| Van Dyke, C | 1 |
| Fein, G | 1 |
| Weiner, MW | 1 |
| Lin, TN | 1 |
| Premkumar, N | 1 |
| MacQuarrie, RA | 1 |
| Carter, SR | 1 |
2 trials available for inositol and Brain Ischemia
| Article | Year |
|---|---|
The profile of hippocampal metabolites differs between Alzheimer's disease and subcortical ischemic vascular dementia, as measured by proton magnetic resonance spectroscopy.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Brain Ischemia; Dementia, Vascular; Female; | 2012 |
[Experience with the medical treatment of chronic cerebrovascular insufficiency: bamethan and inositol nicotinate versus placebo].
Topics: Aged; Brain Ischemia; Chronic Disease; Clinical Trials as Topic; Ethanolamines; Female; Humans; Inos | 1981 |
10 other studies available for inositol and Brain Ischemia
| Article | Year |
|---|---|
Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway.
Topics: Aminopyridines; Animals; Apoptosis; Benzamides; Brain Ischemia; Cyclopropanes; Endoribonucleases; Gl | 2021 |
Potential role of myo-inositol to improve ischemic stroke outcome in diabetic mouse.
Topics: Animals; Brain; Brain Ischemia; Cell Hypoxia; Diabetes Mellitus, Experimental; Glucose; Inositol; Ma | 2018 |
Brain metabolic pattern analysis using a magnetic resonance spectra classification software in experimental stroke.
Topics: Animals; Brain; Brain Ischemia; Creatine; Image Processing, Computer-Assisted; Inositol; Lactic Acid | 2017 |
Simultaneous determination of myo-inositol and scyllo-inositol by MEKC as a rapid monitoring tool for inositol levels.
Topics: Anhydrides; Animals; Brain Ischemia; Chromatography, Micellar Electrokinetic Capillary; Glucose; Gly | 2007 |
Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease.
Topics: Aged; Aspartic Acid; Brain Diseases; Brain Ischemia; Case-Control Studies; Cerebrovascular Circulati | 2008 |
Alteration of intracellular metabolite diffusion in rat brain in vivo during ischemia and reperfusion.
Topics: Animals; Aspartic Acid; Body Water; Brain; Brain Ischemia; Choline; Creatine; Diffusion; Inositol; I | 1995 |
Proton T2 relaxation of cerebral metabolites during transient global ischemia in rat brain.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Image Processing, Computer-Assiste | 1998 |
Decapitation ischemia-induced release of free fatty acids in mouse brain. Relationship with diacylglycerols and lysophospholipids.
Topics: Animals; Brain Chemistry; Brain Ischemia; Choline; Diglycerides; Fatty Acids, Nonesterified; Female; | 1992 |
Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Ischemia; Cerebral Infarction; | 1992 |
Decapitation-induced changes in inositol phosphates in rat brain.
Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Decerebrate State; Inositol; Inositol Phosphates; K | 1990 |