inositol has been researched along with Brain Injuries in 16 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Excerpt | Relevance | Reference |
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" We also did not find a correlation between the amount of Glx and the initial Glasgow Coma Scale score, duration of coma, nor with changes in spectral metabolites, including N-acetyl aspartate, choline, and myoinositol." | 3.72 | Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury. ( Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (12.50) | 18.2507 |
2000's | 9 (56.25) | 29.6817 |
2010's | 5 (31.25) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kierans, AS | 1 |
Kirov, II | 3 |
Gonen, O | 3 |
Haemer, G | 1 |
Nisenbaum, E | 1 |
Babb, JS | 2 |
Grossman, RI | 3 |
Lui, YW | 3 |
Sajja, VS | 1 |
Perrine, SA | 1 |
Ghoddoussi, F | 1 |
Hall, CS | 1 |
Galloway, MP | 1 |
VandeVord, PJ | 1 |
Grossman, EJ | 1 |
Novikov, DS | 1 |
Davitz, MS | 1 |
Inglese, M | 1 |
Fieremans, E | 1 |
Semenova, NA | 1 |
Akhadov, TA | 1 |
Petryaykin, AV | 1 |
Sidorin, SS | 1 |
Lukovenkov, AV | 1 |
Varfolomeev, SD | 1 |
Tal, A | 1 |
Schuhmann, MU | 1 |
Stiller, D | 1 |
Skardelly, M | 1 |
Bernarding, J | 1 |
Klinge, PM | 1 |
Samii, A | 1 |
Samii, M | 1 |
Brinker, T | 1 |
Ashwal, S | 3 |
Holshouser, B | 2 |
Tong, K | 2 |
Serna, T | 2 |
Osterdock, R | 2 |
Gross, M | 2 |
Kido, D | 2 |
Shutter, L | 1 |
Tong, KA | 1 |
Holshouser, BA | 2 |
Babikian, T | 1 |
Freier, MC | 1 |
Riggs, ML | 1 |
Burley, T | 1 |
Pascual, JM | 1 |
Solivera, J | 1 |
Prieto, R | 1 |
Barrios, L | 1 |
López-Larrubia, P | 1 |
Cerdán, S | 1 |
Roda, JM | 1 |
Danielsen, ER | 1 |
Michaelis, T | 1 |
Ross, BD | 1 |
Yamashita, T | 1 |
Shimada, S | 1 |
Yamauchi, A | 1 |
Guo, W | 1 |
Kohmura, E | 1 |
Hayakawa, T | 1 |
Tohyama, M | 1 |
Brooks, WM | 1 |
Stidley, CA | 1 |
Petropoulos, H | 1 |
Jung, RE | 1 |
Weers, DC | 1 |
Friedman, SD | 1 |
Barlow, MA | 1 |
Sibbitt, WL | 1 |
Yeo, RA | 1 |
Garnett, MR | 1 |
Blamire, AM | 1 |
Corkill, RG | 1 |
Cadoux-Hudson, TA | 1 |
Rajagopalan, B | 1 |
Styles, P | 1 |
Khiat, A | 1 |
Yared, Z | 1 |
Bard, C | 1 |
Lacroix, A | 1 |
Boulanger, Y | 1 |
1 trial available for inositol and Brain Injuries
Article | Year |
---|---|
Early proton magnetic resonance spectroscopy in normal-appearing brain correlates with outcome in patients following traumatic brain injury.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Injuries; Choline; Creatine; Disabili | 2000 |
15 other studies available for inositol and Brain Injuries
Article | Year |
---|---|
Myoinositol and glutamate complex neurometabolite abnormality after mild traumatic brain injury.
Topics: Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Caudate Nucleus; Choline; Corpus Striatu | 2014 |
Blast neurotrauma impairs working memory and disrupts prefrontal myo-inositol levels in rats.
Topics: Animals; Betaine; Blast Injuries; Brain Injuries; Creatine; Ethanolamines; gamma-Aminobutyric Acid; | 2014 |
N-acetyl-aspartate levels correlate with intra-axonal compartment parameters from diffusion MRI.
Topics: Adult; Aspartic Acid; Axons; Brain; Brain Injuries; Choline; Creatine; Diffusion Magnetic Resonance | 2015 |
Metabolic dysfunction and relationship in human frontoparietal cortex in severe traumatic brain injury: single-voxel (1)H magnetic resonance spectroscopy study.
Topics: Adolescent; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Child; Child, Preschool; Choline; | 2012 |
Diffuse axonal injury in mild traumatic brain injury: a 3D multivoxel proton MR spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Brain Mapping; Choline; Creatine; Diffuse Axonal I | 2013 |
Metabolic changes in the vicinity of brain contusions: a proton magnetic resonance spectroscopy and histology study.
Topics: Animals; Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatine; Functional Laterality; Glutam | 2003 |
Proton spectroscopy detected myoinositol in children with traumatic brain injury.
Topics: Adolescent; Biomarkers; Brain; Brain Injuries; Child; Child, Preschool; Gliosis; Glutamic Acid; Glut | 2004 |
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Com | 2004 |
Proton MRS in acute traumatic brain injury: role for glutamate/glutamine and choline for outcome prediction.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Cerebral Cortex; Choline; Creatinine; Evoked | 2004 |
MR spectroscopy: predicting long-term neuropsychological outcome following pediatric TBI.
Topics: Adolescent; Aspartic Acid; Brain Injuries; Child; Child, Preschool; Creatine; Female; Glutamic Acid; | 2006 |
Time course of early metabolic changes following diffuse traumatic brain injury in rats as detected by (1)H NMR spectroscopy.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Injuries; Creatine; Diffuse Axona | 2007 |
Three methods of calibration in quantitative proton MR spectroscopy.
Topics: Adult; Aspartic Acid; Body Water; Brain; Brain Chemistry; Brain Injuries; Calibration; Choline; Crea | 1995 |
Induction of Na+/myo-inositol co-transporter mRNA after rat cryogenic injury.
Topics: Animals; Biological Transport; Brain Injuries; Cerebral Cortex; In Situ Hybridization; Inositol; Ion | 1997 |
Metabolic and cognitive response to human traumatic brain injury: a quantitative proton magnetic resonance study.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Choline; Cognition Disorders; Creatinine; Cr | 2000 |
Long-term brain metabolic alterations in exogenous Cushing's syndrome as monitored by proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Brain Injuries; Cell Membrane; Choline; Crea | 2001 |