Page last updated: 2024-10-19

inositol and Aura

inositol has been researched along with Aura in 22 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
" Inositols have proved effective in many disorders; hence, in the current study, we tested potential antiepileptic properties of scyllo-inositol (SCI)-one of the most common commercially available inositols-in zebrafish larvae with pentylenetetrazol-induced seizures."8.31Antiepileptic Properties of Scyllo-Inositol on Pentylenetetrazol-Induced Seizures. ( Antonowski, T; Juranek, J; Podlasz, P; Wiśniewski, K; Wojtkiewicz, J, 2023)
"The effects of seizures on brain lipid metabolism and some recent studies from our laboratory are described in this chapter."6.37The accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy. ( Bazan, NG; Birkle, DL; Reddy, TS; Tang, W, 1986)
"Epilepsy is one of the most devastating neurological diseases and despite significant efforts there is no cure available."5.51Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis. ( Gamkrelidze, G; Kandashvili, M; Kokaia, M; Lepsveridze, E; Lortkipanidze, T; Margvelani, G; Solomonia, R; Tsverava, L, 2019)
" Inositols have proved effective in many disorders; hence, in the current study, we tested potential antiepileptic properties of scyllo-inositol (SCI)-one of the most common commercially available inositols-in zebrafish larvae with pentylenetetrazol-induced seizures."4.31Antiepileptic Properties of Scyllo-Inositol on Pentylenetetrazol-Induced Seizures. ( Antonowski, T; Juranek, J; Podlasz, P; Wiśniewski, K; Wojtkiewicz, J, 2023)
"Valproic acid (VPA) is the most widely prescribed epilepsy treatment worldwide, but its mechanism of action remains unclear."3.78The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. ( Bialer, M; Chang, P; Deranieh, RM; Dham, M; Greenberg, ML; Hoeller, O; Orabi, B; Shimshoni, JA; Walker, MC; Williams, RS; Yagen, B, 2012)
"Compared with normal gray matter, hypothalamic hamartomas were hyperintense on T2-weighted images (93%), hypointense on T1-weighted images (74%), and had reduced N-acetylaspartate and increased myoinositol content shown by MR spectroscopy."3.72MR imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: analysis of 72 cases. ( Berkovic, SF; Coleman, LT; Freeman, JL; Harvey, AS; Jackson, GD; Kean, MJ; Rosenfeld, JV; Wellard, RM, 2004)
"The effects of seizures on brain lipid metabolism and some recent studies from our laboratory are described in this chapter."2.37The accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy. ( Bazan, NG; Birkle, DL; Reddy, TS; Tang, W, 1986)
"Epilepsy is a severe neurological disease characterized by spontaneous recurrent seizures (SRS)."1.72Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats. ( Burjanadze, M; Dashniani, M; Gamkrelidze, G; Kandashvili, M; Kokaia, M; Lagani, V; Lepsveridze, E; Lordkipanidze, T; Solomonia, R; Tsverava, L, 2022)
"Epilepsy is one of the most widespread neurological diseases characterized by spontaneous recurrent seizures."1.51Concentration- and time-dependent effects of myo-inositol on evoked epileptic afterdischarge in the hippocampus in vivo. ( Bilanishvili, IG; Gamkrelidze, GN; Kandashvili, M; Kokaia, M; Lordkipanidze, T; Nanobashvili, ZI; Solomonia, RO, 2019)
"Epilepsy is one of the most devastating neurological diseases and despite significant efforts there is no cure available."1.51Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis. ( Gamkrelidze, G; Kandashvili, M; Kokaia, M; Lepsveridze, E; Lortkipanidze, T; Margvelani, G; Solomonia, R; Tsverava, L, 2019)
"We present a case of infantile onset Krabbe disease with prolonged survival, initial intracranial optic nerves and optic chiasm hypertrophy, and serial changes on cranial magnetic resonance imaging and magnetic resonance spectroscopy."1.38Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease. ( Bunge, M; Mhanni, AA; Ryner, L; Salman, MS; Udow, S, 2012)
"Intracranial arachnoid cysts (ACs) are usually asymptomatic, benign developmental anomalies."1.35Single-voxel magnetic resonance spectroscopy of brain tissue adjacent to arachnoid cysts of epileptic patients. ( Ozcan, C; Ozisik, HI; Sarac, K, 2008)
"Myo-inositol was found to be lower while taking VPA, although no relationship between the change in metabolite concentration, VPA dose or seizure control was observed."1.34The effect of sodium valproate on proton MRS visible neurochemical concentrations. ( Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ, 2007)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's1 (4.55)18.2507
2000's11 (50.00)29.6817
2010's6 (27.27)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Kandashvili, M3
Gamkrelidze, G2
Tsverava, L2
Lordkipanidze, T2
Lepsveridze, E2
Lagani, V1
Burjanadze, M1
Dashniani, M1
Kokaia, M3
Solomonia, R2
Cai, J1
Li, X2
Wu, S1
Tian, Y1
Zhang, Y1
Wei, Z1
Jin, Z1
Chen, X1
Chen, WX1
Gamkrelidze, GN1
Nanobashvili, ZI1
Bilanishvili, IG1
Solomonia, RO1
Barta, H1
Jermendy, A1
Kolossvary, M1
Kozak, LR1
Lakatos, A1
Meder, U1
Szabo, M1
Rudas, G1
Margvelani, G1
Lortkipanidze, T1
Tschampa, HJ1
Urbach, H1
Träber, F1
Sprinkart, AM1
Greschus, S1
Malter, MP1
Surges, R1
Gieseke, J1
Block, W1
Ozisik, HI1
Sarac, K1
Ozcan, C1
Terbach, N1
Williams, RS2
Chang, P1
Orabi, B1
Deranieh, RM1
Dham, M1
Hoeller, O1
Shimshoni, JA1
Yagen, B1
Bialer, M1
Greenberg, ML1
Walker, MC1
Udow, S1
Bunge, M1
Ryner, L1
Mhanni, AA1
Salman, MS1
Ziyeh, S1
Thiel, T1
Spreer, J1
Klisch, J1
Schumacher, M1
Freeman, JL1
Coleman, LT1
Wellard, RM2
Kean, MJ1
Rosenfeld, JV1
Jackson, GD2
Berkovic, SF1
Harvey, AS1
Briellmann, RS1
Musto, A1
Bazan, NG2
Simister, RJ1
McLean, MA3
Barker, GJ3
Duncan, JS3
Zhvaniia, MG1
Solomoniia, RO1
Bikashvili, TZ1
Kotariia, NT1
Chkhikvishvili, TsG1
Kiladze, MT1
Nozadze, MB1
Dzhaparidze, ND1
Stanimirovic, DB1
Bacic, F1
Uematsu, S1
Spatz, M1
Woermann, FG2
Mizuno, S1
Takahashi, Y1
Kato, Z1
Goto, H1
Kondo, N1
Hoshi, H1
Bartlett, PA1
Birkle, DL1
Tang, W1
Reddy, TS1
Wiśniewski, K1
Antonowski, T1
Juranek, J1
Podlasz, P1
Wojtkiewicz, J1

Reviews

4 reviews available for inositol and Aura

ArticleYear
Assessing the causal association between human blood metabolites and the risk of epilepsy.
    Journal of translational medicine, 2022, 09-30, Volume: 20, Issue:1

    Topics: Epilepsy; Genome-Wide Association Study; Humans; Inositol; Mendelian Randomization Analysis; Polymor

2022
Structure-function studies for the panacea, valproic acid.
    Biochemical Society transactions, 2009, Volume: 37, Issue:Pt 5

    Topics: Animals; Anticonvulsants; Bipolar Disorder; Epilepsy; gamma-Aminobutyric Acid; Glycogen Synthase Kin

2009
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
    Epilepsia, 2005, Volume: 46, Issue:5

    Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn

2005
The accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy.
    Advances in neurology, 1986, Volume: 44

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Biomechanical Phenomena; Brain; Diglycerides; Epilepsy

1986

Trials

2 trials available for inositol and Aura

ArticleYear
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
    Magnetic resonance in medicine, 2000, Volume: 44, Issue:3

    Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; D

2000
Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy.
    Brain : a journal of neurology, 2001, Volume: 124, Issue:Pt 2

    Topics: Adult; Analysis of Variance; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Dipeptides; Epilepsy

2001

Other Studies

16 other studies available for inositol and Aura

ArticleYear
Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats.
    International journal of molecular sciences, 2022, Jan-21, Volume: 23, Issue:3

    Topics: Animals; Antinematodal Agents; Disease Models, Animal; Epilepsy; Inositol; Kainic Acid; Male; Memory

2022
Concentration- and time-dependent effects of myo-inositol on evoked epileptic afterdischarge in the hippocampus in vivo.
    Neuroreport, 2019, 11-06, Volume: 30, Issue:16

    Topics: Anticonvulsants; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy; Hipp

2019
Prognostic value of early, conventional proton magnetic resonance spectroscopy in cooled asphyxiated infants.
    BMC pediatrics, 2018, 09-15, Volume: 18, Issue:1

    Topics: Aspartic Acid; Brain; Creatine; Epilepsy; Female; Hearing Loss; Hospital Mortality; Humans; Hypother

2018
Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis.
    BioMed research international, 2019, Volume: 2019

    Topics: Animals; Behavior, Animal; Epilepsy; Inositol; Kainic Acid; Seizures; Time Factors

2019
Proton magnetic resonance spectroscopy in focal cortical dysplasia at 3T.
    Seizure, 2015, Volume: 32

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Child, Preschool; Choline; Creatine; Drug Resistant E

2015
Single-voxel magnetic resonance spectroscopy of brain tissue adjacent to arachnoid cysts of epileptic patients.
    The neurologist, 2008, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Arachnoid Cysts; Aspartic Acid; Brain; Brain Mapping; Child; Choline; Creatine; E

2008
The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium.
    Disease models & mechanisms, 2012, Volume: 5, Issue:1

    Topics: Animals; Anticonvulsants; Dictyostelium; Disease Models, Animal; Dose-Response Relationship, Drug; E

2012
Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease.
    Pediatric neurology, 2012, Volume: 47, Issue:4

    Topics: Anticonvulsants; Aspartic Acid; Brain Chemistry; Choline; Combined Modality Therapy; Creatine; DNA M

2012
Valproate-induced encephalopathy: assessment with MR imaging and 1H MR spectroscopy.
    Epilepsia, 2002, Volume: 43, Issue:9

    Topics: Adult; Anticonvulsants; Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Creatine; Epilepsy

2002
MR imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: analysis of 72 cases.
    AJNR. American journal of neuroradiology, 2004, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Cell Count; Cerebral Cortex; Child; Child, Preschool; Dominance, C

2004
Diacylglycerol kinase epsilon modulates rapid kindling epileptogenesis.
    Epilepsia, 2006, Volume: 47, Issue:2

    Topics: Animals; Diacylglycerol Kinase; Disease Susceptibility; Electric Stimulation; Electrodes, Implanted;

2006
The effect of sodium valproate on proton MRS visible neurochemical concentrations.
    Epilepsy research, 2007, Volume: 74, Issue:2-3

    Topics: Adolescent; Adult; Algorithms; Anticonvulsants; Brain Chemistry; Dipeptides; Epilepsy; Female; Gluta

2007
[The influence of myo-inositol on the ultrastructure of hippocampal CA1 area in kainate treated rats].
    Tsitologiia, 2007, Volume: 49, Issue:11

    Topics: Animals; Anticonvulsants; Astrocytes; Epilepsy; Hippocampus; Inositol; Kainic Acid; Male; Neurons; O

2007
Profile of prostaglandins induced by endothelin-1 in human brain capillary endothelium.
    Neurochemistry international, 1993, Volume: 23, Issue:4

    Topics: Analysis of Variance; Capillaries; Cell Line; Dexamethasone; Endothelin Receptor Antagonists; Endoth

1993
Magnetic resonance spectroscopy of tubers in patients with tuberous sclerosis.
    Acta neurologica Scandinavica, 2000, Volume: 102, Issue:3

    Topics: Adult; Age Factors; Aspartic Acid; Case-Control Studies; Child; Child, Preschool; Creatine; Disease

2000
Antiepileptic Properties of Scyllo-Inositol on Pentylenetetrazol-Induced Seizures.
    International journal of molecular sciences, 2023, Apr-20, Volume: 24, Issue:8

    Topics: Animals; Anticonvulsants; Epilepsy; Larva; Pentylenetetrazole; Seizures; Zebrafish

2023