inositol and Aura
inositol has been researched along with Aura in 22 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Inositols have proved effective in many disorders; hence, in the current study, we tested potential antiepileptic properties of scyllo-inositol (SCI)-one of the most common commercially available inositols-in zebrafish larvae with pentylenetetrazol-induced seizures." | 8.31 | Antiepileptic Properties of Scyllo-Inositol on Pentylenetetrazol-Induced Seizures. ( Antonowski, T; Juranek, J; Podlasz, P; Wiśniewski, K; Wojtkiewicz, J, 2023) |
| "The effects of seizures on brain lipid metabolism and some recent studies from our laboratory are described in this chapter." | 6.37 | The accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy. ( Bazan, NG; Birkle, DL; Reddy, TS; Tang, W, 1986) |
| "Epilepsy is one of the most devastating neurological diseases and despite significant efforts there is no cure available." | 5.51 | Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis. ( Gamkrelidze, G; Kandashvili, M; Kokaia, M; Lepsveridze, E; Lortkipanidze, T; Margvelani, G; Solomonia, R; Tsverava, L, 2019) |
| " Inositols have proved effective in many disorders; hence, in the current study, we tested potential antiepileptic properties of scyllo-inositol (SCI)-one of the most common commercially available inositols-in zebrafish larvae with pentylenetetrazol-induced seizures." | 4.31 | Antiepileptic Properties of Scyllo-Inositol on Pentylenetetrazol-Induced Seizures. ( Antonowski, T; Juranek, J; Podlasz, P; Wiśniewski, K; Wojtkiewicz, J, 2023) |
| "Valproic acid (VPA) is the most widely prescribed epilepsy treatment worldwide, but its mechanism of action remains unclear." | 3.78 | The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. ( Bialer, M; Chang, P; Deranieh, RM; Dham, M; Greenberg, ML; Hoeller, O; Orabi, B; Shimshoni, JA; Walker, MC; Williams, RS; Yagen, B, 2012) |
| "Compared with normal gray matter, hypothalamic hamartomas were hyperintense on T2-weighted images (93%), hypointense on T1-weighted images (74%), and had reduced N-acetylaspartate and increased myoinositol content shown by MR spectroscopy." | 3.72 | MR imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: analysis of 72 cases. ( Berkovic, SF; Coleman, LT; Freeman, JL; Harvey, AS; Jackson, GD; Kean, MJ; Rosenfeld, JV; Wellard, RM, 2004) |
| "The effects of seizures on brain lipid metabolism and some recent studies from our laboratory are described in this chapter." | 2.37 | The accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy. ( Bazan, NG; Birkle, DL; Reddy, TS; Tang, W, 1986) |
| "Epilepsy is a severe neurological disease characterized by spontaneous recurrent seizures (SRS)." | 1.72 | Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats. ( Burjanadze, M; Dashniani, M; Gamkrelidze, G; Kandashvili, M; Kokaia, M; Lagani, V; Lepsveridze, E; Lordkipanidze, T; Solomonia, R; Tsverava, L, 2022) |
| "Epilepsy is one of the most widespread neurological diseases characterized by spontaneous recurrent seizures." | 1.51 | Concentration- and time-dependent effects of myo-inositol on evoked epileptic afterdischarge in the hippocampus in vivo. ( Bilanishvili, IG; Gamkrelidze, GN; Kandashvili, M; Kokaia, M; Lordkipanidze, T; Nanobashvili, ZI; Solomonia, RO, 2019) |
| "Epilepsy is one of the most devastating neurological diseases and despite significant efforts there is no cure available." | 1.51 | Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis. ( Gamkrelidze, G; Kandashvili, M; Kokaia, M; Lepsveridze, E; Lortkipanidze, T; Margvelani, G; Solomonia, R; Tsverava, L, 2019) |
| "We present a case of infantile onset Krabbe disease with prolonged survival, initial intracranial optic nerves and optic chiasm hypertrophy, and serial changes on cranial magnetic resonance imaging and magnetic resonance spectroscopy." | 1.38 | Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease. ( Bunge, M; Mhanni, AA; Ryner, L; Salman, MS; Udow, S, 2012) |
| "Intracranial arachnoid cysts (ACs) are usually asymptomatic, benign developmental anomalies." | 1.35 | Single-voxel magnetic resonance spectroscopy of brain tissue adjacent to arachnoid cysts of epileptic patients. ( Ozcan, C; Ozisik, HI; Sarac, K, 2008) |
| "Myo-inositol was found to be lower while taking VPA, although no relationship between the change in metabolite concentration, VPA dose or seizure control was observed." | 1.34 | The effect of sodium valproate on proton MRS visible neurochemical concentrations. ( Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ, 2007) |
Research
Studies (22)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Kandashvili, M | 3 |
| Gamkrelidze, G | 2 |
| Tsverava, L | 2 |
| Lordkipanidze, T | 2 |
| Lepsveridze, E | 2 |
| Lagani, V | 1 |
| Burjanadze, M | 1 |
| Dashniani, M | 1 |
| Kokaia, M | 3 |
| Solomonia, R | 2 |
| Cai, J | 1 |
| Li, X | 2 |
| Wu, S | 1 |
| Tian, Y | 1 |
| Zhang, Y | 1 |
| Wei, Z | 1 |
| Jin, Z | 1 |
| Chen, X | 1 |
| Chen, WX | 1 |
| Gamkrelidze, GN | 1 |
| Nanobashvili, ZI | 1 |
| Bilanishvili, IG | 1 |
| Solomonia, RO | 1 |
| Barta, H | 1 |
| Jermendy, A | 1 |
| Kolossvary, M | 1 |
| Kozak, LR | 1 |
| Lakatos, A | 1 |
| Meder, U | 1 |
| Szabo, M | 1 |
| Rudas, G | 1 |
| Margvelani, G | 1 |
| Lortkipanidze, T | 1 |
| Tschampa, HJ | 1 |
| Urbach, H | 1 |
| Träber, F | 1 |
| Sprinkart, AM | 1 |
| Greschus, S | 1 |
| Malter, MP | 1 |
| Surges, R | 1 |
| Gieseke, J | 1 |
| Block, W | 1 |
| Ozisik, HI | 1 |
| Sarac, K | 1 |
| Ozcan, C | 1 |
| Terbach, N | 1 |
| Williams, RS | 2 |
| Chang, P | 1 |
| Orabi, B | 1 |
| Deranieh, RM | 1 |
| Dham, M | 1 |
| Hoeller, O | 1 |
| Shimshoni, JA | 1 |
| Yagen, B | 1 |
| Bialer, M | 1 |
| Greenberg, ML | 1 |
| Walker, MC | 1 |
| Udow, S | 1 |
| Bunge, M | 1 |
| Ryner, L | 1 |
| Mhanni, AA | 1 |
| Salman, MS | 1 |
| Ziyeh, S | 1 |
| Thiel, T | 1 |
| Spreer, J | 1 |
| Klisch, J | 1 |
| Schumacher, M | 1 |
| Freeman, JL | 1 |
| Coleman, LT | 1 |
| Wellard, RM | 2 |
| Kean, MJ | 1 |
| Rosenfeld, JV | 1 |
| Jackson, GD | 2 |
| Berkovic, SF | 1 |
| Harvey, AS | 1 |
| Briellmann, RS | 1 |
| Musto, A | 1 |
| Bazan, NG | 2 |
| Simister, RJ | 1 |
| McLean, MA | 3 |
| Barker, GJ | 3 |
| Duncan, JS | 3 |
| Zhvaniia, MG | 1 |
| Solomoniia, RO | 1 |
| Bikashvili, TZ | 1 |
| Kotariia, NT | 1 |
| Chkhikvishvili, TsG | 1 |
| Kiladze, MT | 1 |
| Nozadze, MB | 1 |
| Dzhaparidze, ND | 1 |
| Stanimirovic, DB | 1 |
| Bacic, F | 1 |
| Uematsu, S | 1 |
| Spatz, M | 1 |
| Woermann, FG | 2 |
| Mizuno, S | 1 |
| Takahashi, Y | 1 |
| Kato, Z | 1 |
| Goto, H | 1 |
| Kondo, N | 1 |
| Hoshi, H | 1 |
| Bartlett, PA | 1 |
| Birkle, DL | 1 |
| Tang, W | 1 |
| Reddy, TS | 1 |
| Wiśniewski, K | 1 |
| Antonowski, T | 1 |
| Juranek, J | 1 |
| Podlasz, P | 1 |
| Wojtkiewicz, J | 1 |
Reviews
4 reviews available for inositol and Aura
| Article | Year |
|---|---|
Assessing the causal association between human blood metabolites and the risk of epilepsy.
Topics: Epilepsy; Genome-Wide Association Study; Humans; Inositol; Mendelian Randomization Analysis; Polymor | 2022 |
Structure-function studies for the panacea, valproic acid.
Topics: Animals; Anticonvulsants; Bipolar Disorder; Epilepsy; gamma-Aminobutyric Acid; Glycogen Synthase Kin | 2009 |
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn | 2005 |
The accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Biomechanical Phenomena; Brain; Diglycerides; Epilepsy | 1986 |
Trials
2 trials available for inositol and Aura
| Article | Year |
|---|---|
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; D | 2000 |
Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy.
Topics: Adult; Analysis of Variance; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Dipeptides; Epilepsy | 2001 |
Other Studies
16 other studies available for inositol and Aura
| Article | Year |
|---|---|
Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats.
Topics: Animals; Antinematodal Agents; Disease Models, Animal; Epilepsy; Inositol; Kainic Acid; Male; Memory | 2022 |
Concentration- and time-dependent effects of myo-inositol on evoked epileptic afterdischarge in the hippocampus in vivo.
Topics: Anticonvulsants; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy; Hipp | 2019 |
Prognostic value of early, conventional proton magnetic resonance spectroscopy in cooled asphyxiated infants.
Topics: Aspartic Acid; Brain; Creatine; Epilepsy; Female; Hearing Loss; Hospital Mortality; Humans; Hypother | 2018 |
Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis.
Topics: Animals; Behavior, Animal; Epilepsy; Inositol; Kainic Acid; Seizures; Time Factors | 2019 |
Proton magnetic resonance spectroscopy in focal cortical dysplasia at 3T.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Child, Preschool; Choline; Creatine; Drug Resistant E | 2015 |
Single-voxel magnetic resonance spectroscopy of brain tissue adjacent to arachnoid cysts of epileptic patients.
Topics: Adolescent; Adult; Arachnoid Cysts; Aspartic Acid; Brain; Brain Mapping; Child; Choline; Creatine; E | 2008 |
The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium.
Topics: Animals; Anticonvulsants; Dictyostelium; Disease Models, Animal; Dose-Response Relationship, Drug; E | 2012 |
Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease.
Topics: Anticonvulsants; Aspartic Acid; Brain Chemistry; Choline; Combined Modality Therapy; Creatine; DNA M | 2012 |
Valproate-induced encephalopathy: assessment with MR imaging and 1H MR spectroscopy.
Topics: Adult; Anticonvulsants; Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Creatine; Epilepsy | 2002 |
MR imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: analysis of 72 cases.
Topics: Adolescent; Adult; Aspartic Acid; Cell Count; Cerebral Cortex; Child; Child, Preschool; Dominance, C | 2004 |
Diacylglycerol kinase epsilon modulates rapid kindling epileptogenesis.
Topics: Animals; Diacylglycerol Kinase; Disease Susceptibility; Electric Stimulation; Electrodes, Implanted; | 2006 |
The effect of sodium valproate on proton MRS visible neurochemical concentrations.
Topics: Adolescent; Adult; Algorithms; Anticonvulsants; Brain Chemistry; Dipeptides; Epilepsy; Female; Gluta | 2007 |
[The influence of myo-inositol on the ultrastructure of hippocampal CA1 area in kainate treated rats].
Topics: Animals; Anticonvulsants; Astrocytes; Epilepsy; Hippocampus; Inositol; Kainic Acid; Male; Neurons; O | 2007 |
Profile of prostaglandins induced by endothelin-1 in human brain capillary endothelium.
Topics: Analysis of Variance; Capillaries; Cell Line; Dexamethasone; Endothelin Receptor Antagonists; Endoth | 1993 |
Magnetic resonance spectroscopy of tubers in patients with tuberous sclerosis.
Topics: Adult; Age Factors; Aspartic Acid; Case-Control Studies; Child; Child, Preschool; Creatine; Disease | 2000 |
Antiepileptic Properties of Scyllo-Inositol on Pentylenetetrazol-Induced Seizures.
Topics: Animals; Anticonvulsants; Epilepsy; Larva; Pentylenetetrazole; Seizures; Zebrafish | 2023 |