Page last updated: 2024-10-19

inositol and Atrophy

inositol has been researched along with Atrophy in 14 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
" Cerebral MRI shows hypomyelinated white matter and cerebellar atrophy; 1H-MRS of white matter reveals a marked elevation of myo-inositol."3.73Leukoencephalopathy with ataxia, hypodontia, and hypomyelination. ( Boltshauser, E; Ebinger, F; Harting, I; Hoffmann, GF; Koch, MJ; Martin, E; Rating, D; Schmitt-Mechelke, T; Uhlenberg, B; Weber, L; Wiegand, G; Wolf, NI; Zschocke, J, 2005)
"Mesial temporal lobe epilepsy (mTLE) is characterized by hippocampal atrophy, decreased N-acetyl-aspartate, and a low N-acetyl-aspartate/total creatine ratio, often attributed to neuron loss and gliosis."3.72N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus. ( Errante, LD; Kim, JH; Petroff, OA; Spencer, DD, 2003)
"Furthermore, patients suffering from vascular dementia (VD) had remarkably enhanced TMA/tCr ratios, potentially due to ongoing degradation of myelin."1.32Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy. ( Dierks, T; Frölich, L; Gorriz, C; Herminghaus, S; Lanfermann, H; Maurer, K; Pilatus, U; Wittsack, HJ; Zanella, FE, 2003)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's8 (57.14)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blicher, JU1
Eskildsen, SF1
Stærmose, TG1
Møller, AT1
Figlewski, K1
Near, J1
Wang, W1
Sun, H1
Su, X1
Tan, Q1
Zhang, S1
Xia, C1
Li, L1
Kemp, GJ1
Yue, Q1
Gong, Q1
Llufriu, S1
Kornak, J1
Ratiney, H1
Oh, J1
Brenneman, D1
Cree, BA1
Sampat, M1
Hauser, SL1
Nelson, SJ1
Pelletier, D1
Guillen-Del Castillo, A1
Alonso, J1
Martínez-Valle, F1
Alonso-Vila, S1
Garrido-Castro, AC1
Vilardell-Tarrés, M1
Rovira, Á1
Ordi-Ros, J1
Petroff, OA1
Errante, LD1
Kim, JH1
Spencer, DD1
Herminghaus, S1
Frölich, L1
Gorriz, C1
Pilatus, U1
Dierks, T1
Wittsack, HJ1
Lanfermann, H1
Maurer, K1
Zanella, FE1
Nakashima, S1
Wolf, NI1
Harting, I1
Boltshauser, E1
Wiegand, G1
Koch, MJ1
Schmitt-Mechelke, T1
Martin, E1
Zschocke, J1
Uhlenberg, B1
Hoffmann, GF1
Weber, L1
Ebinger, F1
Rating, D1
Briellmann, RS1
Wellard, RM1
Jackson, GD1
Garrard, P1
Schott, JM1
MacManus, DG1
Hodges, JR1
Fox, NC1
Waldman, AD1
Schubert, MI1
Kalisch, R1
Sotiropoulos, I1
Catania, C1
Sousa, N1
Almeida, OF1
Auer, DP1
Summers, M1
Swanton, J1
Fernando, K1
Dalton, C1
Miller, DH1
Cipolotti, L1
Ron, MA1
Gupta, RK1
Saraswat, VA1
Poptani, H1
Dhiman, RK1
Kohli, A1
Gujral, RB1
Naik, SR1
van der Knaap, MS1
Bakker, HD1
Valk, J1

Reviews

2 reviews available for inositol and Atrophy

ArticleYear
[Inositol].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 12

    Topics: Animals; Atrophy; Biomarkers; Brain; Chromatography, Gas; Diabetic Neuropathies; Gas Chromatography-

2004
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
    Epilepsia, 2005, Volume: 46, Issue:5

    Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn

2005

Other Studies

12 other studies available for inositol and Atrophy

ArticleYear
Short echo-time Magnetic Resonance Spectroscopy in ALS, simultaneous quantification of glutamate and GABA at 3 T.
    Scientific reports, 2019, 11-26, Volume: 9, Issue:1

    Topics: Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Atrophy; Choline; Creatine; Disease Progression;

2019
Increased right amygdala metabolite concentrations in the absence of atrophy in children and adolescents with PTSD.
    European child & adolescent psychiatry, 2019, Volume: 28, Issue:6

    Topics: Adolescent; Amygdala; Aspartic Acid; Atrophy; Biomarkers; Child; Choline; Creatine; Cross-Sectional

2019
Magnetic resonance spectroscopy markers of disease progression in multiple sclerosis.
    JAMA neurology, 2014, Jul-01, Volume: 71, Issue:7

    Topics: Adult; Aspartic Acid; Atrophy; Biomarkers; Case-Control Studies; Disability Evaluation; Disease Prog

2014
Increased myo-inositol in parietal white and gray matter as a biomarker of poor prognosis in neuropsychiatric lupus: a case report.
    Lupus, 2014, Volume: 23, Issue:10

    Topics: Atrophy; Biomarkers; Cognition; Disease Progression; Female; Gray Matter; Humans; Immunosuppressive

2014
N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus.
    Neurology, 2003, May-27, Volume: 60, Issue:10

    Topics: Adolescent; Adult; Anterior Temporal Lobectomy; Aspartic Acid; Atrophy; Creatine; Epilepsy, Temporal

2003
Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy.
    Psychiatry research, 2003, Jul-30, Volume: 123, Issue:3

    Topics: Aged; Alzheimer Disease; Atrophy; Brain; Dementia, Vascular; Energy Metabolism; Female; Glutamic Aci

2003
Leukoencephalopathy with ataxia, hypodontia, and hypomyelination.
    Neurology, 2005, Apr-26, Volume: 64, Issue:8

    Topics: Age of Onset; Anodontia; Ataxia; Atrophy; Basal Ganglia; Body Height; Brain; Cerebellum; Child; Chil

2005
Posterior cingulate neurometabolite profiles and clinical phenotype in frontotemporal dementia.
    Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 2006, Volume: 19, Issue:4

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Atrophy; Dementia; Diagnosis, Differential; Female; Frontal

2006
Effects of altered corticosteroid milieu on rat hippocampal neurochemistry and structure--an in vivo magnetic resonance spectroscopy and imaging study.
    Journal of psychiatric research, 2008, Volume: 42, Issue:11

    Topics: Animals; Aspartic Acid; Atrophy; Choline; Creatine; Dexamethasone; Energy Metabolism; Glucocorticoid

2008
Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:8

    Topics: Adolescent; Adult; Aspartic Acid; Atrophy; Brain; Cerebral Ventricles; Cognition Disorders; Cohort S

2008
Magnetic resonance imaging and localized in vivo proton spectroscopy in patients with fulminant hepatic failure.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:5

    Topics: Adult; Atrophy; Brain; Cerebral Cortex; Female; Glutamine; Hepatic Encephalopathy; Humans; Inositol;

1993
MR imaging and proton spectroscopy in 3-hydroxy-3-methylglutaryl coenzyme A lyase deficiency.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Atrophy; Brain; Brain Diseases, Metabolic; Chil

1998