inositol has been researched along with Atrophy in 14 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
Excerpt | Relevance | Reference |
---|---|---|
" Cerebral MRI shows hypomyelinated white matter and cerebellar atrophy; 1H-MRS of white matter reveals a marked elevation of myo-inositol." | 3.73 | Leukoencephalopathy with ataxia, hypodontia, and hypomyelination. ( Boltshauser, E; Ebinger, F; Harting, I; Hoffmann, GF; Koch, MJ; Martin, E; Rating, D; Schmitt-Mechelke, T; Uhlenberg, B; Weber, L; Wiegand, G; Wolf, NI; Zschocke, J, 2005) |
"Mesial temporal lobe epilepsy (mTLE) is characterized by hippocampal atrophy, decreased N-acetyl-aspartate, and a low N-acetyl-aspartate/total creatine ratio, often attributed to neuron loss and gliosis." | 3.72 | N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus. ( Errante, LD; Kim, JH; Petroff, OA; Spencer, DD, 2003) |
"Furthermore, patients suffering from vascular dementia (VD) had remarkably enhanced TMA/tCr ratios, potentially due to ongoing degradation of myelin." | 1.32 | Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy. ( Dierks, T; Frölich, L; Gorriz, C; Herminghaus, S; Lanfermann, H; Maurer, K; Pilatus, U; Wittsack, HJ; Zanella, FE, 2003) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (14.29) | 18.2507 |
2000's | 8 (57.14) | 29.6817 |
2010's | 4 (28.57) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Blicher, JU | 1 |
Eskildsen, SF | 1 |
Stærmose, TG | 1 |
Møller, AT | 1 |
Figlewski, K | 1 |
Near, J | 1 |
Wang, W | 1 |
Sun, H | 1 |
Su, X | 1 |
Tan, Q | 1 |
Zhang, S | 1 |
Xia, C | 1 |
Li, L | 1 |
Kemp, GJ | 1 |
Yue, Q | 1 |
Gong, Q | 1 |
Llufriu, S | 1 |
Kornak, J | 1 |
Ratiney, H | 1 |
Oh, J | 1 |
Brenneman, D | 1 |
Cree, BA | 1 |
Sampat, M | 1 |
Hauser, SL | 1 |
Nelson, SJ | 1 |
Pelletier, D | 1 |
Guillen-Del Castillo, A | 1 |
Alonso, J | 1 |
Martínez-Valle, F | 1 |
Alonso-Vila, S | 1 |
Garrido-Castro, AC | 1 |
Vilardell-Tarrés, M | 1 |
Rovira, Á | 1 |
Ordi-Ros, J | 1 |
Petroff, OA | 1 |
Errante, LD | 1 |
Kim, JH | 1 |
Spencer, DD | 1 |
Herminghaus, S | 1 |
Frölich, L | 1 |
Gorriz, C | 1 |
Pilatus, U | 1 |
Dierks, T | 1 |
Wittsack, HJ | 1 |
Lanfermann, H | 1 |
Maurer, K | 1 |
Zanella, FE | 1 |
Nakashima, S | 1 |
Wolf, NI | 1 |
Harting, I | 1 |
Boltshauser, E | 1 |
Wiegand, G | 1 |
Koch, MJ | 1 |
Schmitt-Mechelke, T | 1 |
Martin, E | 1 |
Zschocke, J | 1 |
Uhlenberg, B | 1 |
Hoffmann, GF | 1 |
Weber, L | 1 |
Ebinger, F | 1 |
Rating, D | 1 |
Briellmann, RS | 1 |
Wellard, RM | 1 |
Jackson, GD | 1 |
Garrard, P | 1 |
Schott, JM | 1 |
MacManus, DG | 1 |
Hodges, JR | 1 |
Fox, NC | 1 |
Waldman, AD | 1 |
Schubert, MI | 1 |
Kalisch, R | 1 |
Sotiropoulos, I | 1 |
Catania, C | 1 |
Sousa, N | 1 |
Almeida, OF | 1 |
Auer, DP | 1 |
Summers, M | 1 |
Swanton, J | 1 |
Fernando, K | 1 |
Dalton, C | 1 |
Miller, DH | 1 |
Cipolotti, L | 1 |
Ron, MA | 1 |
Gupta, RK | 1 |
Saraswat, VA | 1 |
Poptani, H | 1 |
Dhiman, RK | 1 |
Kohli, A | 1 |
Gujral, RB | 1 |
Naik, SR | 1 |
van der Knaap, MS | 1 |
Bakker, HD | 1 |
Valk, J | 1 |
2 reviews available for inositol and Atrophy
Article | Year |
---|---|
[Inositol].
Topics: Animals; Atrophy; Biomarkers; Brain; Chromatography, Gas; Diabetic Neuropathies; Gas Chromatography- | 2004 |
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn | 2005 |
12 other studies available for inositol and Atrophy
Article | Year |
---|---|
Short echo-time Magnetic Resonance Spectroscopy in ALS, simultaneous quantification of glutamate and GABA at 3 T.
Topics: Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Atrophy; Choline; Creatine; Disease Progression; | 2019 |
Increased right amygdala metabolite concentrations in the absence of atrophy in children and adolescents with PTSD.
Topics: Adolescent; Amygdala; Aspartic Acid; Atrophy; Biomarkers; Child; Choline; Creatine; Cross-Sectional | 2019 |
Magnetic resonance spectroscopy markers of disease progression in multiple sclerosis.
Topics: Adult; Aspartic Acid; Atrophy; Biomarkers; Case-Control Studies; Disability Evaluation; Disease Prog | 2014 |
Increased myo-inositol in parietal white and gray matter as a biomarker of poor prognosis in neuropsychiatric lupus: a case report.
Topics: Atrophy; Biomarkers; Cognition; Disease Progression; Female; Gray Matter; Humans; Immunosuppressive | 2014 |
N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus.
Topics: Adolescent; Adult; Anterior Temporal Lobectomy; Aspartic Acid; Atrophy; Creatine; Epilepsy, Temporal | 2003 |
Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy.
Topics: Aged; Alzheimer Disease; Atrophy; Brain; Dementia, Vascular; Energy Metabolism; Female; Glutamic Aci | 2003 |
Leukoencephalopathy with ataxia, hypodontia, and hypomyelination.
Topics: Age of Onset; Anodontia; Ataxia; Atrophy; Basal Ganglia; Body Height; Brain; Cerebellum; Child; Chil | 2005 |
Posterior cingulate neurometabolite profiles and clinical phenotype in frontotemporal dementia.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Atrophy; Dementia; Diagnosis, Differential; Female; Frontal | 2006 |
Effects of altered corticosteroid milieu on rat hippocampal neurochemistry and structure--an in vivo magnetic resonance spectroscopy and imaging study.
Topics: Animals; Aspartic Acid; Atrophy; Choline; Creatine; Dexamethasone; Energy Metabolism; Glucocorticoid | 2008 |
Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease.
Topics: Adolescent; Adult; Aspartic Acid; Atrophy; Brain; Cerebral Ventricles; Cognition Disorders; Cohort S | 2008 |
Magnetic resonance imaging and localized in vivo proton spectroscopy in patients with fulminant hepatic failure.
Topics: Adult; Atrophy; Brain; Cerebral Cortex; Female; Glutamine; Hepatic Encephalopathy; Humans; Inositol; | 1993 |
MR imaging and proton spectroscopy in 3-hydroxy-3-methylglutaryl coenzyme A lyase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Atrophy; Brain; Brain Diseases, Metabolic; Chil | 1998 |