inositol and Atrophy
inositol has been researched along with Atrophy in 14 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Cerebral MRI shows hypomyelinated white matter and cerebellar atrophy; 1H-MRS of white matter reveals a marked elevation of myo-inositol." | 3.73 | Leukoencephalopathy with ataxia, hypodontia, and hypomyelination. ( Boltshauser, E; Ebinger, F; Harting, I; Hoffmann, GF; Koch, MJ; Martin, E; Rating, D; Schmitt-Mechelke, T; Uhlenberg, B; Weber, L; Wiegand, G; Wolf, NI; Zschocke, J, 2005) |
| "Mesial temporal lobe epilepsy (mTLE) is characterized by hippocampal atrophy, decreased N-acetyl-aspartate, and a low N-acetyl-aspartate/total creatine ratio, often attributed to neuron loss and gliosis." | 3.72 | N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus. ( Errante, LD; Kim, JH; Petroff, OA; Spencer, DD, 2003) |
| "Furthermore, patients suffering from vascular dementia (VD) had remarkably enhanced TMA/tCr ratios, potentially due to ongoing degradation of myelin." | 1.32 | Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy. ( Dierks, T; Frölich, L; Gorriz, C; Herminghaus, S; Lanfermann, H; Maurer, K; Pilatus, U; Wittsack, HJ; Zanella, FE, 2003) |
Research
Studies (14)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Blicher, JU | 1 |
| Eskildsen, SF | 1 |
| Stærmose, TG | 1 |
| Møller, AT | 1 |
| Figlewski, K | 1 |
| Near, J | 1 |
| Wang, W | 1 |
| Sun, H | 1 |
| Su, X | 1 |
| Tan, Q | 1 |
| Zhang, S | 1 |
| Xia, C | 1 |
| Li, L | 1 |
| Kemp, GJ | 1 |
| Yue, Q | 1 |
| Gong, Q | 1 |
| Llufriu, S | 1 |
| Kornak, J | 1 |
| Ratiney, H | 1 |
| Oh, J | 1 |
| Brenneman, D | 1 |
| Cree, BA | 1 |
| Sampat, M | 1 |
| Hauser, SL | 1 |
| Nelson, SJ | 1 |
| Pelletier, D | 1 |
| Guillen-Del Castillo, A | 1 |
| Alonso, J | 1 |
| Martínez-Valle, F | 1 |
| Alonso-Vila, S | 1 |
| Garrido-Castro, AC | 1 |
| Vilardell-Tarrés, M | 1 |
| Rovira, Á | 1 |
| Ordi-Ros, J | 1 |
| Petroff, OA | 1 |
| Errante, LD | 1 |
| Kim, JH | 1 |
| Spencer, DD | 1 |
| Herminghaus, S | 1 |
| Frölich, L | 1 |
| Gorriz, C | 1 |
| Pilatus, U | 1 |
| Dierks, T | 1 |
| Wittsack, HJ | 1 |
| Lanfermann, H | 1 |
| Maurer, K | 1 |
| Zanella, FE | 1 |
| Nakashima, S | 1 |
| Wolf, NI | 1 |
| Harting, I | 1 |
| Boltshauser, E | 1 |
| Wiegand, G | 1 |
| Koch, MJ | 1 |
| Schmitt-Mechelke, T | 1 |
| Martin, E | 1 |
| Zschocke, J | 1 |
| Uhlenberg, B | 1 |
| Hoffmann, GF | 1 |
| Weber, L | 1 |
| Ebinger, F | 1 |
| Rating, D | 1 |
| Briellmann, RS | 1 |
| Wellard, RM | 1 |
| Jackson, GD | 1 |
| Garrard, P | 1 |
| Schott, JM | 1 |
| MacManus, DG | 1 |
| Hodges, JR | 1 |
| Fox, NC | 1 |
| Waldman, AD | 1 |
| Schubert, MI | 1 |
| Kalisch, R | 1 |
| Sotiropoulos, I | 1 |
| Catania, C | 1 |
| Sousa, N | 1 |
| Almeida, OF | 1 |
| Auer, DP | 1 |
| Summers, M | 1 |
| Swanton, J | 1 |
| Fernando, K | 1 |
| Dalton, C | 1 |
| Miller, DH | 1 |
| Cipolotti, L | 1 |
| Ron, MA | 1 |
| Gupta, RK | 1 |
| Saraswat, VA | 1 |
| Poptani, H | 1 |
| Dhiman, RK | 1 |
| Kohli, A | 1 |
| Gujral, RB | 1 |
| Naik, SR | 1 |
| van der Knaap, MS | 1 |
| Bakker, HD | 1 |
| Valk, J | 1 |
Reviews
2 reviews available for inositol and Atrophy
| Article | Year |
|---|---|
[Inositol].
Topics: Animals; Atrophy; Biomarkers; Brain; Chromatography, Gas; Diabetic Neuropathies; Gas Chromatography- | 2004 |
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn | 2005 |
Other Studies
12 other studies available for inositol and Atrophy
| Article | Year |
|---|---|
Short echo-time Magnetic Resonance Spectroscopy in ALS, simultaneous quantification of glutamate and GABA at 3 T.
Topics: Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Atrophy; Choline; Creatine; Disease Progression; | 2019 |
Increased right amygdala metabolite concentrations in the absence of atrophy in children and adolescents with PTSD.
Topics: Adolescent; Amygdala; Aspartic Acid; Atrophy; Biomarkers; Child; Choline; Creatine; Cross-Sectional | 2019 |
Magnetic resonance spectroscopy markers of disease progression in multiple sclerosis.
Topics: Adult; Aspartic Acid; Atrophy; Biomarkers; Case-Control Studies; Disability Evaluation; Disease Prog | 2014 |
Increased myo-inositol in parietal white and gray matter as a biomarker of poor prognosis in neuropsychiatric lupus: a case report.
Topics: Atrophy; Biomarkers; Cognition; Disease Progression; Female; Gray Matter; Humans; Immunosuppressive | 2014 |
N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus.
Topics: Adolescent; Adult; Anterior Temporal Lobectomy; Aspartic Acid; Atrophy; Creatine; Epilepsy, Temporal | 2003 |
Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy.
Topics: Aged; Alzheimer Disease; Atrophy; Brain; Dementia, Vascular; Energy Metabolism; Female; Glutamic Aci | 2003 |
Leukoencephalopathy with ataxia, hypodontia, and hypomyelination.
Topics: Age of Onset; Anodontia; Ataxia; Atrophy; Basal Ganglia; Body Height; Brain; Cerebellum; Child; Chil | 2005 |
Posterior cingulate neurometabolite profiles and clinical phenotype in frontotemporal dementia.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Atrophy; Dementia; Diagnosis, Differential; Female; Frontal | 2006 |
Effects of altered corticosteroid milieu on rat hippocampal neurochemistry and structure--an in vivo magnetic resonance spectroscopy and imaging study.
Topics: Animals; Aspartic Acid; Atrophy; Choline; Creatine; Dexamethasone; Energy Metabolism; Glucocorticoid | 2008 |
Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease.
Topics: Adolescent; Adult; Aspartic Acid; Atrophy; Brain; Cerebral Ventricles; Cognition Disorders; Cohort S | 2008 |
Magnetic resonance imaging and localized in vivo proton spectroscopy in patients with fulminant hepatic failure.
Topics: Adult; Atrophy; Brain; Cerebral Cortex; Female; Glutamine; Hepatic Encephalopathy; Humans; Inositol; | 1993 |
MR imaging and proton spectroscopy in 3-hydroxy-3-methylglutaryl coenzyme A lyase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Atrophy; Brain; Brain Diseases, Metabolic; Chil | 1998 |