inositol has been researched along with Astrocytosis in 19 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Strongly elevated concentrations of myo-inositol in conjunction with normal or increased choline-containing compounds in all regions investigated point to astrocytosis and demyelination." | 3.72 | Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease. ( Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Haupt, M; Meins, M; Sperner, J; Stephani, U, 2003) |
| "Mesial temporal lobe epilepsy (mTLE) is characterized by hippocampal atrophy, decreased N-acetyl-aspartate, and a low N-acetyl-aspartate/total creatine ratio, often attributed to neuron loss and gliosis." | 3.72 | N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus. ( Errante, LD; Kim, JH; Petroff, OA; Spencer, DD, 2003) |
| "Compared with normal gray matter, hypothalamic hamartomas were hyperintense on T2-weighted images (93%), hypointense on T1-weighted images (74%), and had reduced N-acetylaspartate and increased myoinositol content shown by MR spectroscopy." | 3.72 | MR imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: analysis of 72 cases. ( Berkovic, SF; Coleman, LT; Freeman, JL; Harvey, AS; Jackson, GD; Kean, MJ; Rosenfeld, JV; Wellard, RM, 2004) |
| " Clinical studies of SI showed promising benefits on mild to moderate AD, however, with limitations on dosage regime." | 1.46 | A guanidine-appended scyllo-inositol derivative AAD-66 enhances brain delivery and ameliorates Alzheimer's phenotypes. ( Chung, SK; Das, S; Jung, HY; Kim, KT; Kim, YK; Lee, D; Lee, J; Lee, WS; Lim, S; Luo, W, 2017) |
| "Prion diseases are fatal chronic neurodegenerative diseases." | 1.34 | MRI and MRS alterations in the preclinical phase of murine prion disease: association with neuropathological and behavioural changes. ( Anthony, DC; Blamire, AM; Broom, KA; Griffin, JL; Lowe, JP; Perry, VH; Scott, H; Sibson, NR; Styles, P, 2007) |
| "The fulminating form of subacute sclerosing panencephalitis is an extremely rare condition." | 1.32 | Subacute sclerosing panencephalitis with fulminating course: follow-up magnetic resonance spectroscopy (MRS) findings. ( Alkan, A; Aslan, M; Kutlu, R; Sarac, K; Sigirci, A; Yakinci, C, 2004) |
| "A 3-year-old boy with Lowe syndrome had bilateral periatrial hyperintense lesions intermixed with small cyst-like changes in the periatial regions of the deep white matter at MR imaging." | 1.32 | Lowe syndrome: proton mr spectroscopy, and diffusion mr imaging. ( Sener, RN, 2004) |
| "Most of the brain tumors were characterized by strongly reduced total N-acetylaspartyl compounds and marked increases of myo-inositol and choline-containing compounds, consistent with a lack of neuroaxonal tissue and a proliferation of glial cells." | 1.31 | Quantitative proton magnetic resonance spectroscopy of focal brain lesions. ( Dechent, P; Frahm, J; Hanefeld, F; Herms, J; Markakis, E; Maxton, C; Wilken, B, 2000) |
| "The mechanisms behind the demyelination that is characteristic of multiple sclerosis (MS) are still poorly understood." | 1.30 | Inflammatory CNS demyelination: histopathologic correlation with in vivo quantitative proton MR spectroscopy. ( Bitsch, A; Brück, W; Bruhn, H; Frahm, J; Lassmann, H; Stringaris, A; Vougioukas, V, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 14 (73.68) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Jung, C | 1 |
| Ichesco, E | 1 |
| Ratai, EM | 2 |
| Gonzalez, RG | 2 |
| Burdo, T | 1 |
| Loggia, ML | 1 |
| Harris, RE | 1 |
| Napadow, V | 1 |
| Tackley, G | 1 |
| Kong, Y | 1 |
| Minne, R | 1 |
| Messina, S | 1 |
| Winkler, A | 1 |
| Cavey, A | 1 |
| Everett, R | 1 |
| DeLuca, GC | 1 |
| Weir, A | 1 |
| Craner, M | 1 |
| Tracey, I | 1 |
| Palace, J | 1 |
| Stagg, CJ | 1 |
| Emir, U | 1 |
| Lee, D | 1 |
| Lee, WS | 1 |
| Lim, S | 1 |
| Kim, YK | 1 |
| Jung, HY | 1 |
| Das, S | 1 |
| Lee, J | 1 |
| Luo, W | 1 |
| Kim, KT | 1 |
| Chung, SK | 1 |
| Mazgaj, R | 1 |
| Tal, A | 1 |
| Goetz, R | 1 |
| Lazar, M | 1 |
| Rothman, K | 1 |
| Messinger, JW | 1 |
| Malaspina, D | 1 |
| Gonen, O | 1 |
| Sarchielli, P | 1 |
| Presciutti, O | 1 |
| Alberti, A | 1 |
| Tarducci, R | 1 |
| Gobbi, G | 1 |
| Galletti, F | 1 |
| Costa, C | 1 |
| Eusebi, P | 1 |
| Calabresi, P | 1 |
| Duarte, JM | 1 |
| Carvalho, RA | 1 |
| Cunha, RA | 1 |
| Gruetter, R | 1 |
| Brockmann, K | 1 |
| Dechent, P | 2 |
| Meins, M | 1 |
| Haupt, M | 1 |
| Sperner, J | 1 |
| Stephani, U | 1 |
| Frahm, J | 3 |
| Hanefeld, F | 2 |
| Petroff, OA | 1 |
| Errante, LD | 1 |
| Kim, JH | 1 |
| Spencer, DD | 1 |
| Freeman, JL | 1 |
| Coleman, LT | 1 |
| Wellard, RM | 1 |
| Kean, MJ | 1 |
| Rosenfeld, JV | 1 |
| Jackson, GD | 1 |
| Berkovic, SF | 1 |
| Harvey, AS | 1 |
| Alkan, A | 1 |
| Kutlu, R | 1 |
| Sigirci, A | 1 |
| Aslan, M | 1 |
| Sarac, K | 1 |
| Yakinci, C | 1 |
| Ashwal, S | 1 |
| Holshouser, B | 1 |
| Tong, K | 1 |
| Serna, T | 1 |
| Osterdock, R | 1 |
| Gross, M | 1 |
| Kido, D | 1 |
| Sener, RN | 1 |
| Kim, JP | 1 |
| Lentz, MR | 1 |
| Westmoreland, SV | 1 |
| Greco, JB | 1 |
| Halpern, E | 1 |
| Lackner, AA | 1 |
| Masliah, E | 1 |
| Coulthard, E | 1 |
| Firbank, M | 1 |
| English, P | 1 |
| Welch, J | 1 |
| Birchall, D | 1 |
| O'Brien, J | 1 |
| Griffiths, TD | 1 |
| Broom, KA | 1 |
| Anthony, DC | 1 |
| Lowe, JP | 1 |
| Griffin, JL | 1 |
| Scott, H | 1 |
| Blamire, AM | 1 |
| Styles, P | 1 |
| Perry, VH | 1 |
| Sibson, NR | 1 |
| Brunetti-Pierri, N | 1 |
| Bhattacharjee, MB | 1 |
| Wang, ZJ | 1 |
| Wenger, DA | 1 |
| Potocki, L | 1 |
| Hunter, J | 1 |
| Scaglia, F | 1 |
| Prestel, J | 1 |
| Gempel, K | 1 |
| Hauser, TK | 1 |
| Schweitzer, K | 1 |
| Prokisch, H | 1 |
| Ahting, U | 1 |
| Freudenstein, D | 1 |
| Bueltmann, E | 1 |
| Naegele, T | 1 |
| Berg, D | 1 |
| Klopstock, T | 1 |
| Gasser, T | 1 |
| Bitsch, A | 1 |
| Bruhn, H | 1 |
| Vougioukas, V | 1 |
| Stringaris, A | 1 |
| Lassmann, H | 1 |
| Brück, W | 1 |
| Wilken, B | 1 |
| Herms, J | 1 |
| Maxton, C | 1 |
| Markakis, E | 1 |
19 other studies available for inositol and Astrocytosis
| Article | Year |
|---|---|
Magnetic resonance imaging of neuroinflammation in chronic pain: a role for astrogliosis?
Topics: Choline; Chronic Pain; Creatine; Gliosis; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Res | 2020 |
An In-vivo 1H-MRS short-echo time technique at 7T: Quantification of metabolites in chronic multiple sclerosis and neuromyelitis optica brain lesions and normal appearing brain tissue.
Topics: Adult; Aquaporin 4; Aspartic Acid; Autoantibodies; Autoantigens; Brain Chemistry; Female; Gliosis; G | 2021 |
A guanidine-appended scyllo-inositol derivative AAD-66 enhances brain delivery and ameliorates Alzheimer's phenotypes.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Brain; Cognition; Gliosis; G | 2017 |
Hypo-metabolism of the rostral anterior cingulate cortex associated with working memory impairment in 18 cases of schizophrenia.
Topics: Adult; Aging; Aspartic Acid; Creatine; Female; Gliosis; Gyrus Cinguli; Humans; Inositol; Intelligenc | 2016 |
A 1H magnetic resonance spectroscopy study in patients with obstructive sleep apnea.
Topics: Adult; Aged; Aspartic Acid; Brain Chemistry; Cell Death; Choline; Comorbidity; Creatinine; Female; F | 2008 |
Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Caffeine; Central Nervous System Stimulants; Chronic Disease; Diabetes Melli | 2009 |
Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease.
Topics: Alexander Disease; Aspartic Acid; Brain; Child; Child, Preschool; Demyelinating Diseases; Disease Pr | 2003 |
N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus.
Topics: Adolescent; Adult; Anterior Temporal Lobectomy; Aspartic Acid; Atrophy; Creatine; Epilepsy, Temporal | 2003 |
MR imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: analysis of 72 cases.
Topics: Adolescent; Adult; Aspartic Acid; Cell Count; Cerebral Cortex; Child; Child, Preschool; Dominance, C | 2004 |
Subacute sclerosing panencephalitis with fulminating course: follow-up magnetic resonance spectroscopy (MRS) findings.
Topics: Aspartic Acid; Brain; Cerebral Cortex; Child, Preschool; Choline; Creatine; Diagnosis, Differential; | 2004 |
Proton spectroscopy detected myoinositol in children with traumatic brain injury.
Topics: Adolescent; Biomarkers; Brain; Brain Injuries; Child; Child, Preschool; Gliosis; Glutamic Acid; Glut | 2004 |
Lowe syndrome: proton mr spectroscopy, and diffusion mr imaging.
Topics: Aspartic Acid; Brain; Child, Preschool; Choline; Creatine; Cysts; Diffusion Magnetic Resonance Imagi | 2004 |
Relationships between astrogliosis and 1H MR spectroscopic measures of brain choline/creatine and myo-inositol/creatine in a primate model.
Topics: Animals; Choline; Creatine; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Hydrog | 2005 |
Proton magnetic resonance spectroscopy in frontotemporal dementia.
Topics: Aged; Aspartic Acid; Biomarkers; Cerebral Cortex; Dementia; Female; Frontal Lobe; Gliosis; Gyrus Cin | 2006 |
MRI and MRS alterations in the preclinical phase of murine prion disease: association with neuropathological and behavioural changes.
Topics: Animals; Aspartic Acid; Astrocytes; Body Water; Brain; Choline; Creatine; Diffusion; Disease Models, | 2007 |
Brain proton magnetic resonance spectroscopy and neuromuscular pathology in a patient with GM1 gangliosidosis.
Topics: Aspartic Acid; Axons; Biomarkers; Brain; Female; Gangliosidosis, GM1; Gliosis; Humans; Infant; Inosi | 2008 |
Clinical and molecular characterisation of a Parkinson family with a novel PINK1 mutation.
Topics: Adult; Aged; Basal Ganglia; Biomarkers; Cell Line; DNA Mutational Analysis; Energy Metabolism; Femal | 2008 |
Inflammatory CNS demyelination: histopathologic correlation with in vivo quantitative proton MR spectroscopy.
Topics: Adult; Aspartic Acid; Axons; Biopsy, Needle; Blood-Brain Barrier; Brain; Cell Division; Choline; Dem | 1999 |
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
Topics: Adolescent; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; | 2000 |