inositol has been researched along with Anaplastic Astrocytoma in 15 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inositol uptake was measured at concentrations of 25, 40 and 50 microM in human astrocytoma cell cultures treated for 1-3 weeks with pharmacologically relevant concentrations of LiCl, valproic acid or carbamazepine as well as in control cultures that had not been treated with any drug." | 7.70 | Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations. ( Belmaker, RH; Bersudsky, Y; Hertz, L; Simkin, M; Wolfson, M; Zinger, E, 2000) |
| "The coupling of muscarinic receptor-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis by phospholipase C to resynthesis of phosphatidylinositol (PtdIns) and the ability of Li+ to inhibit this after cellular inositol depletion were studied in 1321N1 astrocytoma cells cultured in medium +/- inositol (40 microM)." | 7.69 | The mechanism of muscarinic receptor-stimulated phosphatidylinositol resynthesis in 1321N1 astrocytoma cells and its inhibition by Li+. ( Batty, IH; Downes, CP, 1995) |
| "The uptake of inositol into 1321N1 astrocytoma cells was studied by measurement of the accumulation of free [3H]inositol within the intracellular pool." | 7.68 | The characteristics, capacity and receptor regulation of inositol uptake in 1321N1 astrocytoma cells. ( Batty, IH; Downes, CP; Fennel, M; Michie, A, 1993) |
| "In an inositol-depleted 1321 N1 astrocytoma cell line, propranolol at 0." | 7.68 | Subcellular distribution of agonist-stimulated phosphatidylinositol synthesis in 1321 N1 astrocytoma cells. ( Downes, CP; Sillence, DJ, 1993) |
| "The compartmentation of inositol phospholipids was examined by using a combination of radiolabelling approaches in intact and permeabilized 1321N1 astrocytoma cells." | 3.70 | Evidence for a model of integrated inositol phospholipid pools implies an essential role for lipid transport in the maintenance of receptor-mediated phospholipase C activity in 1321N1 cells. ( Batty, IH; Currie, RA; Downes, CP, 1998) |
| "Inositol uptake was measured at concentrations of 25, 40 and 50 microM in human astrocytoma cell cultures treated for 1-3 weeks with pharmacologically relevant concentrations of LiCl, valproic acid or carbamazepine as well as in control cultures that had not been treated with any drug." | 3.70 | Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations. ( Belmaker, RH; Bersudsky, Y; Hertz, L; Simkin, M; Wolfson, M; Zinger, E, 2000) |
| "The coupling of muscarinic receptor-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis by phospholipase C to resynthesis of phosphatidylinositol (PtdIns) and the ability of Li+ to inhibit this after cellular inositol depletion were studied in 1321N1 astrocytoma cells cultured in medium +/- inositol (40 microM)." | 3.69 | The mechanism of muscarinic receptor-stimulated phosphatidylinositol resynthesis in 1321N1 astrocytoma cells and its inhibition by Li+. ( Batty, IH; Downes, CP, 1995) |
| "The uptake of inositol into 1321N1 astrocytoma cells was studied by measurement of the accumulation of free [3H]inositol within the intracellular pool." | 3.68 | The characteristics, capacity and receptor regulation of inositol uptake in 1321N1 astrocytoma cells. ( Batty, IH; Downes, CP; Fennel, M; Michie, A, 1993) |
| "In an inositol-depleted 1321 N1 astrocytoma cell line, propranolol at 0." | 3.68 | Subcellular distribution of agonist-stimulated phosphatidylinositol synthesis in 1321 N1 astrocytoma cells. ( Downes, CP; Sillence, DJ, 1993) |
| "myo-Inositol plays a key role in signal transduction and osmotic regulation events in the CNS." | 1.30 | Differentiated human NT2-N neurons possess a high intracellular content of myo-inositol. ( Agranoff, BW; Fisher, SK; Novak, JE; Turner, RS, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murphy, M | 2 |
| Loosemore, A | 1 |
| Clifton, AG | 1 |
| Howe, FA | 2 |
| Tate, AR | 1 |
| Cudlip, SA | 2 |
| Wilkins, PR | 1 |
| Griffiths, JR | 2 |
| Bell, BA | 2 |
| Barton, SJ | 1 |
| Stubbs, M | 1 |
| Saunders, DE | 1 |
| Wilkins, P | 1 |
| Opstad, KS | 1 |
| Doyle, VL | 1 |
| McLean, MA | 1 |
| Bowen, BC | 1 |
| Londoño, A | 1 |
| Castillo, M | 2 |
| Armao, D | 1 |
| Kwock, L | 2 |
| Suzuki, K | 1 |
| Hagberg, G | 1 |
| Burlina, AP | 1 |
| Mader, I | 1 |
| Roser, W | 1 |
| Radue, EW | 1 |
| Seelig, J | 1 |
| Batty, IH | 3 |
| Downes, CP | 4 |
| Heuillet, E | 1 |
| Ménager, J | 1 |
| Fardin, V | 1 |
| Flamand, O | 1 |
| Bock, M | 1 |
| Garret, C | 1 |
| Crespo, A | 1 |
| Fallourd, AM | 1 |
| Doble, A | 1 |
| Michie, A | 1 |
| Fennel, M | 1 |
| Sillence, DJ | 1 |
| Currie, RA | 1 |
| Novak, JE | 1 |
| Turner, RS | 1 |
| Agranoff, BW | 1 |
| Fisher, SK | 1 |
| Wolfson, M | 1 |
| Bersudsky, Y | 1 |
| Zinger, E | 1 |
| Simkin, M | 1 |
| Belmaker, RH | 1 |
| Hertz, L | 1 |
| Smith, JK | 1 |
| Nakahata, N | 1 |
| Abe, MT | 1 |
| Nakanishi, H | 1 |
| Masters, SB | 1 |
| Quinn, MT | 1 |
| Brown, JH | 1 |
15 other studies available for inositol and Anaplastic Astrocytoma
| Article | Year |
|---|---|
The contribution of proton magnetic resonance spectroscopy (1HMRS) to clinical brain tumour diagnosis.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatinine; Humans; Inositol; Magn | 2002 |
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inosi | 2003 |
Glial neoplasms without elevated choline-creatine ratios.
Topics: Astrocytoma; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Humans; I | 2003 |
Unusual MR spectroscopic imaging pattern of an astrocytoma: lack of elevated choline and high myo-inositol and glycine levels.
Topics: Adult; Astrocytoma; Brain Neoplasms; Choline; Glycine; Humans; Inositol; Magnetic Resonance Spectros | 2003 |
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminan | 1995 |
The mechanism of muscarinic receptor-stimulated phosphatidylinositol resynthesis in 1321N1 astrocytoma cells and its inhibition by Li+.
Topics: Astrocytoma; CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase; Enzyme Activation; Inositol; Lit | 1995 |
Characterization of a human NK1 tachykinin receptor in the astrocytoma cell line U 373 MG.
Topics: Astrocytoma; Binding Sites; Humans; Inositol; Inositol Phosphates; Receptors, Neurokinin-2; Receptor | 1993 |
The characteristics, capacity and receptor regulation of inositol uptake in 1321N1 astrocytoma cells.
Topics: Astrocytoma; Carrier Proteins; Inositol; Kinetics; Receptors, Cell Surface; Receptors, Muscarinic; S | 1993 |
Subcellular distribution of agonist-stimulated phosphatidylinositol synthesis in 1321 N1 astrocytoma cells.
Topics: Astrocytoma; Carbachol; Humans; Inositol; Lithium; Phosphatidylinositols; Propranolol; Tumor Cells, | 1993 |
Evidence for a model of integrated inositol phospholipid pools implies an essential role for lipid transport in the maintenance of receptor-mediated phospholipase C activity in 1321N1 cells.
Topics: Astrocytoma; Carbachol; Cell Compartmentation; Cell Membrane Permeability; Cytosol; Guanosine 5'-O-( | 1998 |
Differentiated human NT2-N neurons possess a high intracellular content of myo-inositol.
Topics: Antineoplastic Agents; Astrocytoma; Biological Transport; Cell Differentiation; Cells, Cultured; Hum | 1999 |
Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations.
Topics: Antimanic Agents; Astrocytoma; Bipolar Disorder; Brain; Brain Neoplasms; Carbamazepine; Dose-Respons | 2000 |
Correlation of myo-inositol levels and grading of cerebral astrocytomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Child; Chil | 2000 |
PGJ2 and delta 12PGJ2 inhibit cell growth accompanied with inhibition of phosphoinositide turnover in human astrocytoma cells.
Topics: Astrocytoma; Carbachol; Cell Division; Cyclic AMP; DNA; GTP-Binding Proteins; Histamine; Humans; Ino | 1990 |
Agonist-induced desensitization of muscarinic receptor-mediated calcium efflux without concomitant desensitization of phosphoinositide hydrolysis.
Topics: Astrocytoma; Calcium; Carbachol; Cell Line; Chromatography, Ion Exchange; Humans; Hydrolysis; Inosit | 1985 |